{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T21:03:38Z","timestamp":1787951018586,"version":"build-2784847793"},"reference-count":27,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100007112","name":"University of Cape Town","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007112","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001322","name":"South African Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001322","id-type":"DOI","asserted-by":"publisher"}]},{"name":"South African National Research Foundation"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry Letters"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1016\/j.bmcl.2016.11.077","type":"journal-article","created":{"date-parts":[[2016,11,25]],"date-time":"2016-11-25T03:45:15Z","timestamp":1480045515000},"page":"658-661","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Synthesis and biological characterisation of ester and amide derivatives of fusidic acid as antiplasmodial agents"],"prefix":"10.1016","volume":"27","author":[{"given":"Marlene","family":"Espinoza-Moraga","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kawaljit","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathew","family":"Njoroge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gurminder","family":"Kaur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Okombo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"De Kock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Wittlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Chibale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmcl.2016.11.077_b0005","series-title":"World Malaria Report 2015; Geneva","author":"World Health Organisation","year":"2015"},{"key":"10.1016\/j.bmcl.2016.11.077_b0010","series-title":"Guidelines for the treatment of malaria","author":"World Health Organization","year":"2015"},{"key":"10.1016\/j.bmcl.2016.11.077_b0015","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1172\/JCI21682","volume":"113","author":"White","year":"2004","journal-title":"J Clin Invest"},{"key":"10.1016\/j.bmcl.2016.11.077_b0020","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1056\/NEJMoa0808859","volume":"361","author":"Dondorp","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.bmcl.2016.11.077_b0025","doi-asserted-by":"crossref","first-page":"458","DOI":"10.2174\/09298673113206660291","volume":"21","author":"Negi","year":"2014","journal-title":"Curr Med Chem"},{"issue":"suppl 1","key":"10.1016\/j.bmcl.2016.11.077_b0030","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1186\/1475-2875-10-S1-S2","volume":"10","author":"Guantai","year":"2011","journal-title":"Malar J"},{"issue":"suppl 1","key":"10.1016\/j.bmcl.2016.11.077_b0035","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1186\/1475-2875-10-S1-S3","volume":"10","author":"Wells","year":"2011","journal-title":"Malar J"},{"key":"10.1016\/j.bmcl.2016.11.077_b0040","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.3390\/molecules16032146","volume":"16","author":"Nogueira","year":"2011","journal-title":"Molecules"},{"key":"10.1016\/j.bmcl.2016.11.077_b0045","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1038\/193987a0","volume":"193","author":"Godtfredsen","year":"1962","journal-title":"Nature"},{"key":"10.1016\/j.bmcl.2016.11.077_b0050","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1016\/S0140-6736(62)91968-2","volume":"279","author":"Godtfredsen","year":"1962","journal-title":"Lancet"},{"key":"10.1016\/j.bmcl.2016.11.077_b0055","doi-asserted-by":"crossref","first-page":"S45","DOI":"10.1016\/S0924-8579(98)00073-9","volume":"12","author":"Collignon","year":"1999","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.bmcl.2016.11.077_b0060","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1128\/jcm.33.7.1712-1715.1995","volume":"33","author":"Toma","year":"1995","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.bmcl.2016.11.077_b0065","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.ijantimicag.2009.10.023","volume":"35","author":"Pfaller","year":"2010","journal-title":"Int J Antimicrob Agents"},{"issue":"suppl 7","key":"10.1016\/j.bmcl.2016.11.077_b0070","doi-asserted-by":"crossref","first-page":"S477","DOI":"10.1093\/cid\/cir163","volume":"52","author":"Jones","year":"2011","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.bmcl.2016.11.077_b0075","doi-asserted-by":"crossref","first-page":"3320","DOI":"10.1021\/bi00874a034","volume":"5","author":"Harvey","year":"1966","journal-title":"Biochemistry"},{"key":"10.1016\/j.bmcl.2016.11.077_b0080","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/0006-291X(68)90226-X","volume":"33","author":"Kinoshita","year":"1968","journal-title":"Biochem Biophys Res Commun"},{"issue":"suppl 2","key":"10.1016\/j.bmcl.2016.11.077_b0085","doi-asserted-by":"crossref","first-page":"S23","DOI":"10.1016\/S0924-8579(98)00071-5","volume":"12","author":"Turnidge","year":"1999","journal-title":"Int J Antimicrob Agents"},{"issue":"suppl 7","key":"10.1016\/j.bmcl.2016.11.077_b0090","doi-asserted-by":"crossref","first-page":"S527","DOI":"10.1093\/cid\/cir168","volume":"52","author":"Kraus","year":"2011","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.bmcl.2016.11.077_b0095","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/S0140-6736(85)91234-6","volume":"325","author":"Black","year":"1985","journal-title":"Lancet"},{"key":"10.1016\/j.bmcl.2016.11.077_b0100","doi-asserted-by":"crossref","first-page":"e20633","DOI":"10.1371\/journal.pone.0020633","volume":"6","author":"Johnson","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1016\/j.bmcl.2016.11.077_b0105","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.molbiopara.2013.10.003","volume":"192","author":"Gupta","year":"2013","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.bmcl.2016.11.077_b0110","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1039\/C5MD00343A","volume":"6","author":"Kaur","year":"2015","journal-title":"Med Chem Commun"},{"key":"10.1016\/j.bmcl.2016.11.077_b0115","doi-asserted-by":"crossref","first-page":"739","DOI":"10.4269\/ajtmh.1993.48.739","volume":"48","author":"Makler","year":"1993","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.bmcl.2016.11.077_b0120","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1038\/nature02779","volume":"430","author":"Vennerstrom","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.bmcl.2016.11.077_b0125","doi-asserted-by":"crossref","first-page":"5536","DOI":"10.1016\/j.bmc.2008.04.006","volume":"16","author":"Mishra","year":"2008","journal-title":"Bioorg Med Chem"},{"key":"10.1016\/j.bmcl.2016.11.077_b0130","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1021\/jm00319a004","volume":"9","author":"Godtfredsen","year":"1966","journal-title":"J Med Chem"},{"key":"10.1016\/j.bmcl.2016.11.077_b0135","series-title":"Advances in applied microbiology","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0065-2164(08)70148-5","volume":"Vol. 25","author":"Von Daehne","year":"1979"}],"container-title":["Bioorganic & Medicinal Chemistry Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X16312410?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X16312410?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T07:15:47Z","timestamp":1760771747000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960894X16312410"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["S0960894X16312410"],"URL":"https:\/\/doi.org\/10.1016\/j.bmcl.2016.11.077","relation":{},"ISSN":["0960-894X"],"issn-type":[{"value":"0960-894X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Synthesis and biological characterisation of ester and amide derivatives of fusidic acid as antiplasmodial agents","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmcl.2016.11.077","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}