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White amorphous powder. 1H NMR (300 MHz, [D6]DMSO): \u03b4\u202f=\u202f10.03 (1H, s), 9.40 (1H, s), 7.58 (2H, d, J\u202f=\u202f8.7 Hz), 6.90 (2H, d, J\u202f=\u202f8.7 Hz), 5.69 (2H, m), 5.20 (1H, t, J\u202f=\u202f5.0 Hz), 4.50 (2H, t, J\u202f=\u202f7.3 Hz), 3.97 (2H, t, J\u202f=\u202f6.4 Hz), 3.64 (2H, q, J\u202f=\u202f5.4 Hz), 3.02 (2H, t, J\u202f=\u202f5.6 Hz), 2.46 (3H, s), 1.70-1.95 (4H, m), 1.34 ppm (8H, m); 13C NMR (75.47 MHz, CD3OD): \u03b4\u202f=\u202f160.3, 153.9, 141.9, 135.9, 133.7, 127.1 (2C), 124.8, 113.9 (2C), 67.5, 59.9, 53.2, 29.4, 29.0, 28.7, 28.6, 28.5, 25.7, 25.4, 10.3 ppm; FT-IR (cm-1) \u03bd 3307, 3065, 2929, 2858, 1631, 1520, 1260, 1057, 840; MS C21H32N3O3S (ESI+) m\/z (%) : 203.6 ([(M+H)\/2]+, 100%), 406.2 (M+, 42%), 204.1 ([(M+2H)\/2]+, 39%), 407.3 ([M+H]+, 12%); HRMS calcd for C21H32N3O3S+ 406.2164, found 406.2183."},{"key":"10.1016\/j.bmcl.2019.06.045_b0130","doi-asserted-by":"crossref","first-page":"2590","DOI":"10.1128\/AAC.47.8.2590-2597.2003","article-title":"Potent inhibitors of Plasmodium phospholipid metabolism with a broad spectrum of in vitro antimalarial activities","volume":"47","author":"Ancelin","year":"2003","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.bmcl.2019.06.045_b0135","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1128\/AAC.16.6.710","article-title":"Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique","volume":"16","author":"Desjardins","year":"1979","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.bmcl.2019.06.045_b0140","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/S0020-7519(00)00035-7","article-title":"Optimisation of flow cytometric measurement of parasitaemia in plasmodium-infected mice","volume":"30","author":"Barkan","year":"2000","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.bmcl.2019.06.045_b0145","unstructured":"4a-c, 4g, 4i, 4l: ED50 i.p. > 20\u202fmg\/kg, ED50 p.o. > 90\u202fmg\/kg; 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