{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T12:42:38Z","timestamp":1782736958332,"version":"3.54.5"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,7,5]],"date-time":"2023-07-05T00:00:00Z","timestamp":1688515200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry Letters"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.bmcl.2023.129391","type":"journal-article","created":{"date-parts":[[2023,6,25]],"date-time":"2023-06-25T10:15:39Z","timestamp":1687688139000},"page":"129391","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Synthesis and biological evaluation of 2-(Tetrazol-5-yl)sulfonylacetamides as inhibitors of Mycobacterium tuberculosis and Mycobacterium marinum"],"prefix":"10.1016","volume":"92","author":[{"given":"Robin","family":"Henches","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3205-7644","authenticated-orcid":false,"given":"Th\u00e9o","family":"Ozga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4131-3444","authenticated-orcid":false,"given":"Yamin","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengchao","family":"Tu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3814-8575","authenticated-orcid":false,"given":"Craig L.","family":"Francis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmcl.2023.129391_b0005","unstructured":"WHO, Global Tuberculosis Report 2022. https:\/\/www.who.int\/teams\/global-tuberculosis-programme\/tb-reports\/global-tuberculosis-report-2022 Retrieved 28 April 2023."},{"key":"10.1016\/j.bmcl.2023.129391_b0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmcl.2021.127784","article-title":"Synthesis of novel quinoxaline-alkynyl derivatives and their anti-mycobacterium tuberculosis activity","volume":"35","author":"Raphoko","year":"2021","journal-title":"Bioorg Med Chem Lett"},{"key":"10.1016\/j.bmcl.2023.129391_b0015","doi-asserted-by":"crossref","first-page":"811","DOI":"10.3390\/molecules24040811","article-title":"Identification of novel benzoxa-[2,1,3]-diazole substituted amino acid hydrazides as potential anti-tubercular agents","volume":"24","author":"Brown","year":"2019","journal-title":"Molecules"},{"key":"10.1016\/j.bmcl.2023.129391_b0020","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1071\/CH13325","article-title":"Construction of the CSIRO fragment library","volume":"66","author":"Francis","year":"2013","journal-title":"Austr J Chem"},{"key":"10.1016\/j.bmcl.2023.129391_b0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2022.114982","article-title":"1-Benzyloxy-5-phenyltetrazole derivatives highly active against androgen receptor-dependent prostate cancer cells","volume":"246","author":"Zhao","year":"2023","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.bmcl.2023.129391_b0030","doi-asserted-by":"crossref","first-page":"3152","DOI":"10.1016\/j.bmcl.2008.05.003","article-title":"Structure-based prediction of Mycobacterium tuberculosis shikimate kinase inhibitors by high-throughput virtual screening","volume":"18","author":"Segura-Cabrera","year":"2008","journal-title":"Bioorg Med Chem Lett"},{"key":"10.1016\/j.bmcl.2023.129391_b0035","first-page":"168","article-title":"Synthesis of some antifungal and anti-tubercular 1, 2, 4-triazole analogues","volume":"1","author":"Mali","year":"2009","journal-title":"Int J ChemTech Res"},{"key":"10.1016\/j.bmcl.2023.129391_b0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmcl.2023.129189","article-title":"2-[(2-Amino-6-methylpyrimidin-4-yl)sulfanyl]-N-arylacetamides: discovery of a new class of anti-tubercular agents and prospects for their further structural modification","volume":"83","author":"Erkin","year":"2023","journal-title":"Bioorg Med Chem Lett"},{"key":"10.1016\/j.bmcl.2023.129391_b0045","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.ejmech.2014.05.069","article-title":"1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria","volume":"82","author":"Karabanovich","year":"2014","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.bmcl.2023.129391_b0050","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1039\/C4MD00301B","article-title":"Tetrazole regioisomers in the development of nitro group-containing antitubercular agents","volume":"6","author":"Karabanovich","year":"2015","journal-title":"Med Chem Commun"},{"key":"10.1016\/j.bmcl.2023.129391_b0055","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.ejmech.2016.11.041","article-title":"S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents","volume":"126","author":"Karabanovich","year":"2017","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.bmcl.2023.129391_b0060","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.ejmech.2017.02.058","article-title":"Structure-activity relationship studies on 3,5-dinitrophenyl tetrazoles as antitubercular agents","volume":"130","author":"N\u011bme\u010dek","year":"2017","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.bmcl.2023.129391_b0065","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1080\/10426507.2022.2117812","article-title":"Synthesis, and docking studies of novel tetrazole-S-alkyl derivatives as antimicrobial agents","volume":"198","author":"\u00c7evik","year":"2023","journal-title":"Phosphorus, Sulfur Silicon Related Elements"},{"key":"10.1016\/j.bmcl.2023.129391_b0070","first-page":"453","article-title":"Phenyl vinyl sulfone and sulfoxide","volume":"7","author":"Paquette","year":"1990","journal-title":"Org Synth Coll."},{"key":"10.1016\/j.bmcl.2023.129391_b0075","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1055\/s-2001-17519","article-title":"Synthesis of rofecoxib, (MK 0966, Vioxx\u00ae 4-(4\u2019-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone), a selective and orally active inhibitor of cyclooxygenase-2","volume":"12","author":"Th\u00e9rien","year":"2001","journal-title":"Synthesis"},{"key":"10.1016\/j.bmcl.2023.129391_b0080","doi-asserted-by":"crossref","first-page":"5518","DOI":"10.1016\/j.bmcl.2008.09.004","article-title":"Synthesis and use of sulfonamide-, sulfoxide-, or sulfone-containing aminoglycoside\u2013CoA bisubstrates as mechanistic probes for aminoglycoside N-6\u2019-acetyltransferase","volume":"18","author":"Gao","year":"2008","journal-title":"Bioorg Med Chem Lett"},{"key":"10.1016\/j.bmcl.2023.129391_b0085","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1080\/00397919908086223","article-title":"A mild and efficient procedure for the oxidation of organic sulfides to sulfones by use of urea-hydrogen peroxide\/trifluoroacetic anhydride system","volume":"29","author":"Balicki","year":"1999","journal-title":"Synth Commun"},{"key":"10.1016\/j.bmcl.2023.129391_b0090","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1071\/CH9780397","article-title":"Purine analogues as amplifiers of phleomycin. II. Some s-triazolo[4,3-a]pyridines, s-triazolo[4,3- or 1,5-a]pyrimidines and s-triazolo[3,4-b]benzothiazoles","volume":"31","author":"Brown","year":"1978","journal-title":"Austr J Chem"},{"key":"10.1016\/j.bmcl.2023.129391_b0095","unstructured":"K. Ashton, M. P. Bourbeau, F.\u2013T. Hong, L. Liu, N. Nishimura, M. H. Norman, S. F. Poon, M. M. Stec, D. J. St Jean Jr, N. A. Tamayo, K. C. Yang (Amgen Inc.) \u201cSulfonyl compounds that interact with glucokinase regulatory protein\u201d WO 2013 123444 A1 (p217)."},{"key":"10.1016\/j.bmcl.2023.129391_b0100","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1038\/s41467-019-08464-y","article-title":"The compound TB47 is highly bactericidal against Mycobacterium ulcerans in a Buruli ulcer mouse model","volume":"10","author":"Liu","year":"2019","journal-title":"Nat Commun"},{"key":"10.1016\/j.bmcl.2023.129391_b0105","doi-asserted-by":"crossref","first-page":"6322","DOI":"10.1128\/JB.182.22.6322-6330.2000","article-title":"Comparative genetic analysis of Mycobacterium ulcerans and Mycobacterium marinum reveals evidence of recent divergence","volume":"182","author":"Stinear","year":"2000","journal-title":"J Bacteriol"},{"key":"10.1016\/j.bmcl.2023.129391_b0110","doi-asserted-by":"crossref","first-page":"e29774","DOI":"10.1371\/journal.pone.0029774","article-title":"Autoluminescent Mycobacterium tuberculosis for rapid, real-time, non-invasive assessment of drug and vaccine efficacy","volume":"7","author":"Zhang","year":"2012","journal-title":"PLoS One1"},{"key":"10.1016\/j.bmcl.2023.129391_b0115","first-page":"1","article-title":"Engineering more stable, selectable marker-free autoluminescent mycobacteria by one step","volume":"10","author":"Yang","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.bmcl.2023.129391_b0120","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1039\/C8MD00389K","article-title":"Design, synthesis, and in vitro biological evaluation of novel benzimidazole tethered allylidenehydrazinylmethylthiazole derivatives as potent inhibitors of Mycobacterium tuberculosis","volume":"10","author":"Surineni","year":"2019","journal-title":"Med Chem Commun"},{"key":"10.1016\/j.bmcl.2023.129391_b0125","doi-asserted-by":"crossref","first-page":"12592","DOI":"10.1002\/anie.201306241","article-title":"Rapid, stable, chemoselective labeling of thiols with Julia-Kocie\u0144ski like reagents: a serum-stable alternative to maleimide-based protein conjugation","volume":"52","author":"Toda","year":"2013","journal-title":"Angew Chem, Int Ed"},{"key":"10.1016\/j.bmcl.2023.129391_b0130","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1016\/j.tetlet.2019.05.007","article-title":"1-Methyl-1H-tetrazol-5-yl (MT) sulfones in the Julia-Kocienski olefination: comparison with the PT and the TBT sulfones","volume":"60","author":"Ando","year":"2019","journal-title":"Tetrahedron Lett"},{"key":"10.1016\/j.bmcl.2023.129391_b0135","doi-asserted-by":"crossref","first-page":"2875","DOI":"10.1016\/j.bmcl.2018.07.028","article-title":"Development of a new thiol-reactive prosthetic group for site-specific labeling of biomolecules with radioactive iodine","volume":"28","author":"Shim","year":"2018","journal-title":"Bioorg Med Chem Lett"},{"key":"10.1016\/j.bmcl.2023.129391_b0140","doi-asserted-by":"crossref","first-page":"5673","DOI":"10.1021\/acs.jmedchem.8b01153","article-title":"Emerging and re-emerging warheads for targeted covalent inhibitors: applications in medicinal chemistry and chemical biology","volume":"62","author":"Gehringer","year":"2019","journal-title":"J Med Chem"},{"key":"10.1016\/j.bmcl.2023.129391_b0145","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1021\/jm901137j","article-title":"New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays","volume":"53","author":"Baell","year":"2010","journal-title":"J Med Chem"},{"key":"10.1016\/j.bmcl.2023.129391_b0150","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1021\/acschembio.7b00903","article-title":"Seven year itch: pan-assay interference compounds (PAINS) in 2017\u2013utility and limitations","volume":"13","author":"Baell","year":"2018","journal-title":"ACS Chem Biol"},{"key":"10.1016\/j.bmcl.2023.129391_b0155","doi-asserted-by":"crossref","first-page":"2893","DOI":"10.1073\/pnas.81.9.2893","article-title":"Mechanism of the inhibition of the y-carboxylation of glutamic acid by N-methylthiotetrazole-containing antibiotics","volume":"81","author":"Lipsky","year":"1984","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.bmcl.2023.129391_b0160","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1002\/j.1552-4604.1990.tb03476.x","article-title":"Third generation cephalosporins: safety profiles after 10 years of clinical use","volume":"30","author":"Neu","year":"1990","journal-title":"J Clin Pharmacol"}],"container-title":["Bioorganic & Medicinal Chemistry Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X2300269X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X2300269X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T07:49:03Z","timestamp":1760773743000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960894X2300269X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":32,"alternative-id":["S0960894X2300269X"],"URL":"https:\/\/doi.org\/10.1016\/j.bmcl.2023.129391","relation":{},"ISSN":["0960-894X"],"issn-type":[{"value":"0960-894X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Synthesis and biological evaluation of 2-(Tetrazol-5-yl)sulfonylacetamides as inhibitors of Mycobacterium tuberculosis and Mycobacterium marinum","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmcl.2023.129391","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 My employer is CSIRO, other authors' employer is Guangzhou Institutes of Biomedicine & Health, CAS. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"129391"}}