{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T21:28:26Z","timestamp":1785792506352,"version":"3.56.0"},"reference-count":69,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic & Medicinal Chemistry Letters"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.bmcl.2024.129709","type":"journal-article","created":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T17:31:38Z","timestamp":1710523898000},"page":"129709","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Hydrazyl hydroxycoumarins as new potential conquerors towards Pseudomonas aeruginosa"],"prefix":"10.1016","volume":"103","author":[{"given":"Jiang-Sheng","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nisar","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuo","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng-He","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bmcl.2024.129709_h0005","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1056\/NEJM196311072691907","article-title":"New penicillins","volume":"269","author":"Klein","year":"1963","journal-title":"N Engl J Med"},{"key":"10.1016\/j.bmcl.2024.129709_h0010","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1159\/000220427","article-title":"Prognostic significance of penicillin serum levels and protein binding in clinical medicine a review of current studies","volume":"10","author":"Warren","year":"1965","journal-title":"Chemotherapy"},{"key":"10.1016\/j.bmcl.2024.129709_h0015","doi-asserted-by":"crossref","first-page":"7138","DOI":"10.1039\/D2CS00460G","article-title":"Metal organic framework-based antibacterial agents and their underlying mechanisms","volume":"51","author":"Han","year":"2022","journal-title":"Chem Soc Rev"},{"key":"10.1016\/j.bmcl.2024.129709_h0020","doi-asserted-by":"crossref","first-page":"104","DOI":"10.2174\/1573406414666181106124852","article-title":"Design and synthesis of novel sulfonamide-derived triazoles and bioactivity exploration","volume":"16","author":"He","year":"2020","journal-title":"Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0025","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1038\/nature17042","article-title":"Antibacterial drug discovery in the resistance era","volume":"529","author":"Brown","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.bmcl.2024.129709_h0030","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1021\/acs.jmedchem.1c01592","article-title":"Natural berberine-derived azolyl ethanols as new structural antibacterial agents against drug-resistant Escherichia coli","volume":"65","author":"Sun","year":"2022","journal-title":"J Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0035","doi-asserted-by":"crossref","first-page":"239","DOI":"10.2174\/092986712803414213","article-title":"Recent researches in triazole compounds as medicinal drugs","volume":"19","author":"Zhou","year":"2012","journal-title":"Curr Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2019.111661","article-title":"Alkynyl gold(I) complexes derived from 3-hydroxyflavones as multi-targeted drugs against colon cancer","volume":"183","author":"Marmol","year":"2019","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0045","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1360\/SSC-2021-0003","article-title":"Synthesis of naphthalimide triazoles with a novel structural framework and their anti-Aspergillus fumigatus effects","volume":"51","author":"Zhang","year":"2021","journal-title":"Sci Sin Chim"},{"key":"10.1016\/j.bmcl.2024.129709_h0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2022.105718","article-title":"Novel metronidazole-derived three-component hybrids as promising broad-spectrum agents to combat oppressive bacterial resistance","volume":"122","author":"Li","year":"2022","journal-title":"Bioorg Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2023.115773","article-title":"Identification of unique indolylcyanoethylenyl sulfonylanilines as novel structural scaffolds of potential antibacterial agents","volume":"260","author":"Zhou","year":"2023","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0060","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1007\/s00203-023-03699-2","article-title":"A review of current antibiotic resistance and promising antibiotics with novel modes of action to combat antibiotic resistance","volume":"205","author":"Chen","year":"2023","journal-title":"Arch Microbiol"},{"key":"10.1016\/j.bmcl.2024.129709_h0065","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1080\/17460441.2023.2198701","article-title":"What is an ideal antibiotic and what does this mean for future drug discovery and design?","volume":"18","author":"Sandiford","year":"2023","journal-title":"Expert Opin Drug Discov"},{"key":"10.1016\/j.bmcl.2024.129709_h0070","doi-asserted-by":"crossref","first-page":"10403","DOI":"10.1021\/acs.chemrev.9b00145","article-title":"Correction to coumarin-based small-molecule fluorescent chemosensors","volume":"119","author":"Cao","year":"2019","journal-title":"Chem Rev"},{"key":"10.1016\/j.bmcl.2024.129709_h0075","doi-asserted-by":"crossref","first-page":"3884","DOI":"10.2174\/1381612811319210013","article-title":"Current developments of coumarin compounds in medicinal chemistry","volume":"19","author":"Peng","year":"2013","journal-title":"Curr Pharm Des"},{"key":"10.1016\/j.bmcl.2024.129709_h0080","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.ejmech.2019.01.072","article-title":"Design and synthesis of aminothiazolyl norfloxacin analogues as potential antimicrobial agents and their biological evaluation","volume":"1667","author":"Wang","year":"2019","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2019.103434","article-title":"Ethylenic conjugated coumarin thiazolidinediones as new efficient antimicrobial modulators against clinical methicillin-resistant Staphylococcus aureus","volume":"94","author":"Hu","year":"2020","journal-title":"Bioorg Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2022.114192","article-title":"Discovery of unique thiazolidinone-conjugated coumarins as novel broad spectrum antibacterial agents","volume":"232","author":"Yang","year":"2022","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2024.116219","article-title":"Novel aminothiazoximone-corbelled ethoxycarbonylpyrimidones with antibiofilm activity to conquer gram-negative bacteria through potential multitargeting effects","volume":"268","author":"Li","year":"2024","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0100","doi-asserted-by":"crossref","first-page":"4225","DOI":"10.1021\/acs.jmedchem.8b01928","article-title":"Structural basis for DNA gyrase interaction with coumermycin A1","volume":"62","author":"Broeck","year":"2019","journal-title":"J Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2020.112832","article-title":"Antibacterial activities with the structure-activity relationship of coumarin derivatives","volume":"207","author":"Qin","year":"2020","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0110","article-title":"Benzopyrone-mediated quinolones as potential multitargeting antibacterial agents","volume":"263","author":"Li","year":"2023","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2022.105855","article-title":"Coumarin thiazoles as unique structural skeleton of potential antimicrobial agents","volume":"124","author":"Yang","year":"2022","journal-title":"Bioorg Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0120","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1038\/s41586-020-2761-3","article-title":"Synthetic group a streptogramin antibiotics that overcome vat resistance","volume":"586","author":"Li","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.bmcl.2024.129709_h0125","article-title":"Antibacterial plant compounds, extracts and essential oils: an updated review on their effects and putative mechanisms of action","volume":"90","author":"Alvarez","year":"2021","journal-title":"Phytomedicine"},{"key":"10.1016\/j.bmcl.2024.129709_h0130","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/ptr.6532","article-title":"Aloe-emodin: a review of its pharmacology, toxicity, and pharmacokinetics","volume":"34","author":"Dong","year":"2019","journal-title":"Phytother Res"},{"key":"10.1016\/j.bmcl.2024.129709_h0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmcl.2021.128198","article-title":"A facile reaction to access novel structural sulfonyl-hybridized imidazolyl ethanols as potential DNA-targeting antibacterial agents","volume":"47","author":"Bheemanaboina","year":"2021","journal-title":"Bioorg Med Chem Lett"},{"key":"10.1016\/j.bmcl.2024.129709_h0140","doi-asserted-by":"crossref","first-page":"4391","DOI":"10.1021\/acsbiomaterials.8b00972","article-title":"Aloe emodin\/carbon nanoparticle hybrid gels with lightinduced and long-term antibacterial activity","volume":"4","author":"Xi","year":"2018","journal-title":"ACS Biomater Sci Eng"},{"key":"10.1016\/j.bmcl.2024.129709_h0145","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.biopha.2017.10.080","article-title":"Inhibitory effect of aloe emodin mediated photodynamic therapy on human oral mucosa carcinoma in vitro and in vivo","volume":"97","author":"Liu","year":"2018","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.bmcl.2024.129709_h0150","doi-asserted-by":"crossref","first-page":"157","DOI":"10.3389\/fcimb.2019.00157","article-title":"Aloe-emodin attenuates Staphylococcus aureus pathogenicity by interfering with the oligomerization of \u03b1-toxin","volume":"9","author":"Jiang","year":"2019","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.bmcl.2024.129709_b0055","article-title":"Beyond silver sulfadiazine: a dive into more than 50 years of research and development on metal complexes of sulfanilamides in medicinal inorganic chemistry","volume":"490","author":"Nunes","year":"2023","journal-title":"Coord Chem Rev"},{"key":"10.1016\/j.bmcl.2024.129709_h0160","doi-asserted-by":"crossref","first-page":"4488","DOI":"10.1021\/acs.jmedchem.5b01678","article-title":"Novel 3-aminothiazolquinolones: design, synthesis, bioactive evaluation, SARs, and preliminary antibacterial mechanism","volume":"59","author":"Cui","year":"2016","journal-title":"J Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0165","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1039\/C8MD00301G","article-title":"Novel organophosphorus aminopyrimidines as unique structural DNA-targeting membrane active inhibitors towards drug-resistant methicillinresistant Staphylococcus aureus","volume":"9","author":"Li","year":"2018","journal-title":"Med Chem Commun"},{"key":"10.1016\/j.bmcl.2024.129709_h0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2022.106035","article-title":"Aloe emodin-conjugated sulfonyl hydrazones as novel type of antibacterial modulators against S. aureus 25923 through multifaceted synergistic effects","volume":"127","author":"Deng","year":"2022","journal-title":"Bioorg Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0175","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.ijantimicag.2018.11.010","article-title":"Antibiotic discovery: history, methods and perspectives","volume":"53","author":"Durand","year":"2019","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.bmcl.2024.129709_h0180","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1360\/N032018-00098","article-title":"Researches and applications of nitroimidazole heterocycles in medicinal chemistry","volume":"49","author":"Li","year":"2019","journal-title":"Sci Sin Chim"},{"key":"10.1016\/j.bmcl.2024.129709_h0185","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1002\/med.21290","article-title":"Comprehensive review in current developments of imidazole-based medicinal chemistry","volume":"34","author":"Zhang","year":"2014","journal-title":"Med Res Rev"},{"key":"10.1016\/j.bmcl.2024.129709_h0190","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1021\/bm2017959","article-title":"Molecular spectroscopy evidence of berberine binding to DNA: comparative binding and thermodynamic profile of intercalation","volume":"13","author":"Li","year":"2012","journal-title":"Biomacromolecules"},{"key":"10.1016\/j.bmcl.2024.129709_h0195","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1039\/C6MD00688D","article-title":"Design, synthesis and biological evaluation of novel schiff base-bridged tetrahydroprotoberberine triazoles as a new type of potential antimicrobial agents","volume":"8","author":"Duan","year":"2017","journal-title":"Med Chem Commun"},{"key":"10.1016\/j.bmcl.2024.129709_h0200","doi-asserted-by":"crossref","first-page":"2768","DOI":"10.1016\/j.bmcl.2016.04.070","article-title":"Discovery of novel berberine imidazoles as safe antimicrobial agents by down regulating ROS generation","volume":"26","author":"Wen","year":"2016","journal-title":"Bioorg Med Chem Lett"},{"key":"10.1016\/j.bmcl.2024.129709_b0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2022.114521","article-title":"Discovery of novel phenylhydrazyl-based oxindole-thiolazoles as potent antibacterial agents toward Pseudomonas aeruginosa","volume":"239","author":"Li","year":"2022","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0210","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2022.114188","article-title":"Dihydropyrimidinone imidazoles as unique structural antibacterial agents for drug-resistant gram-negative pathogens","volume":"232","author":"Yang","year":"2022","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0215","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1002\/asia.202100146","article-title":"Pyrimidinetrione-imidazoles as a unique structural type of potential agents towards Candida albicans: design, synthesis and biological evaluation","volume":"16","author":"Sui","year":"2021","journal-title":"Chem Asian J"},{"key":"10.1016\/j.bmcl.2024.129709_h0220","doi-asserted-by":"crossref","first-page":"2322","DOI":"10.1021\/acs.jafc.2c08293","article-title":"New efforts toward aminothiazolylquinolones with multitargeting antibacterial potential","volume":"71","author":"Zhang","year":"2023","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0225","doi-asserted-by":"crossref","first-page":"2511","DOI":"10.3390\/molecules28062511","article-title":"Synthesis and biological evaluation of piperazine hybridized coumarin indolylcyanoenones with antibacterial potential","volume":"28","author":"Zeng","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.bmcl.2024.129709_h0230","doi-asserted-by":"crossref","first-page":"3645","DOI":"10.1002\/cjoc.202300429","article-title":"Discovery of alkaloid quinazolone-derived imidazolenones with novel structural scaffolds of multitargeting antibacterial potential","volume":"41","author":"Dai","year":"2023","journal-title":"Chin J Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0235","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1080\/14756360802447636","article-title":"Metal based isatinderived sulfonamides: their synthesis, characterization, coordination behavior and biological activity","volume":"24","author":"Chohan","year":"2009","journal-title":"J Enzyme Inhib Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2019.111348","article-title":"Bio-sensing of organophosphorus pesticides: a review","volume":"140","author":"Pundir","year":"2019","journal-title":"Biosens Bioelectron"},{"key":"10.1016\/j.bmcl.2024.129709_h0245","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/j.ejmech.2009.12.022","article-title":"Synthesis and antimicrobial studies on novel sulfonamides containing 4-azidomethyl coumarin","volume":"45","author":"Basanagouda","year":"2010","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2023.115452","article-title":"Thiazolyl hydrazineylidenyl indolones as unique potential multitargeting broad-spectrum antimicrobial agents","volume":"256","author":"Zhao","year":"2023","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0255","doi-asserted-by":"crossref","first-page":"4910","DOI":"10.1021\/acs.jmedchem.2c02042","article-title":"Azolylpyrimidinediols as novel structural scaffolds of DNA-groove binders against intractable acinetobacter baumannii","volume":"66","author":"Tan","year":"2023","journal-title":"J Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0260","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmcl.2022.128695","article-title":"Natural aloe emodin-hybridized sulfonamide aminophosphates as novel potential membrane-perturbing and DNA-intercalating agents against enterococcus faecalis","volume":"64","author":"Deng","year":"2022","journal-title":"Bioorg Med Chem Lett"},{"key":"10.1016\/j.bmcl.2024.129709_b0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2023.115088","article-title":"Benzenesulfonyl thiazoloimines as unique multitargeting antibacterial agents towards enterococcus faecalis","volume":"248","author":"Zhou","year":"2023","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0270","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2020.152478","article-title":"Dual mechanisms suppress meloxicam bioactivation relative to sudoxicam","volume":"440","author":"Barnette","year":"2020","journal-title":"Toxicology"},{"key":"10.1016\/j.bmcl.2024.129709_h0275","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2023.116107","article-title":"Discovery of benzopyridone cyanoacetates as new type of potential broad-spectrum antibacterial candidates","volume":"265","author":"Zhang","year":"2024","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0280","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.jpha.2020.05.004","article-title":"Current status and future directions of high-throughput ADME screening in drug discovery","volume":"10","author":"Shou","year":"2020","journal-title":"J Pharm Anal"},{"key":"10.1016\/j.bmcl.2024.129709_h0285","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmcl.2022.128885","article-title":"Pyrimidineconjugated fluoroquinolones as new potential broad-spectrum antibacterial agents","volume":"73","author":"Tan","year":"2022","journal-title":"Bioorg Med Chem Lett"},{"key":"10.1016\/j.bmcl.2024.129709_h0290","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmcl.2021.127995","article-title":"Unique para-aminobenzenesulfonyl oxadiazoles as novel structural potential membrane active antibacterial agents towards drug resistant methicillin resistant Staphylococcus aureus","volume":"41","author":"Wang","year":"2021","journal-title":"Bioorg Med Chem Lett"},{"key":"10.1016\/j.bmcl.2024.129709_h0295","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/antibiotics10060701","article-title":"Donnan potential across the outer membrane of gram-negative bacteria and its effect on the permeability of antibiotics","volume":"10","author":"Alegun","year":"2021","journal-title":"Antibiotics"},{"key":"10.1016\/j.bmcl.2024.129709_h0300","doi-asserted-by":"crossref","DOI":"10.3390\/membranes11120947","article-title":"A brief introduction to some aspects of the fluid-mosaic model of cell membrane structure and its importance in membrane lipid replacement","volume":"11","author":"Nicolson","year":"2021","journal-title":"Membranes"},{"key":"10.1016\/j.bmcl.2024.129709_b0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2020.103629","article-title":"Novel diindoloazepinone derivatives as DNA minor groove binding agents with selective topoisomerase I inhibition: design, synthesis, biological evaluation and docking studies","volume":"99","author":"Kadagathur","year":"2020","journal-title":"Bioorg Chem"},{"key":"10.1016\/j.bmcl.2024.129709_b0125","doi-asserted-by":"crossref","first-page":"7831","DOI":"10.1021\/acs.jafc.1c02545","article-title":"Natural berberine-hybridized benzimidazoles as novel unique bactericides against Staphylococcus aureus","volume":"69","author":"Sun","year":"2021","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h9000","doi-asserted-by":"crossref","first-page":"5776","DOI":"10.1039\/C4NJ01932F","article-title":"Synthesis of novel sulfonamide azoles via C-N cleavage of sulfonamides by azole ring and relational antimicrobial study","volume":"39","author":"Zhang","year":"2015","journal-title":"New J Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h9005","doi-asserted-by":"crossref","first-page":"711","DOI":"10.4155\/fmc-2017-0160","article-title":"Novel naphthalimide nitroimidazoles as multitargeting antibacterial agents against resistant Acinetobacter baumannii","volume":"10","author":"Kang","year":"2018","journal-title":"Future Med Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h9010","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1021\/acs.molpharmaceut.8b01021","article-title":"Sulfonamide-derived four-component molecular hybrids as novel DNA-targeting membrane active potentiators against clinical Escherichia coli","volume":"16","author":"Hu","year":"2019","journal-title":"Mol Pharm"},{"key":"10.1016\/j.bmcl.2024.129709_h0320","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1039\/C4MD00266K","article-title":"Synthesis of tetrazole compounds as a novel type of potential antimicrobial agents and their synergistic effects with clinical drugs and interactions with calf thymus DNA","volume":"6","author":"Dai","year":"2015","journal-title":"Med Chem Commun"},{"key":"10.1016\/j.bmcl.2024.129709_h0325","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1039\/C4MD00281D","article-title":"Synthesis and biological evaluation of a new class of quinazolinone azoles as potential antimicrobial agents and their interactions with calf thymus DNA and human serum albumin","volume":"6","author":"Peng","year":"2015","journal-title":"Med Chem Commun"},{"key":"10.1016\/j.bmcl.2024.129709_h0330","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1007\/s11426-015-0351-0","article-title":"Coumarin-derived azolyl ethanols: synthesis, antimicrobial evaluation and preliminary action mechanism study","volume":"59","author":"Peng","year":"2016","journal-title":"Sci China Chem"},{"key":"10.1016\/j.bmcl.2024.129709_h0335","article-title":"Discovery of benzopyridone cyanoacetates as new type of potential broad-spectrum antibacterial candidates","volume":"265","author":"Zhang","year":"2023","journal-title":"Eur J Med Chem"}],"container-title":["Bioorganic & Medicinal Chemistry Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X24001112?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960894X24001112?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T18:52:29Z","timestamp":1712170349000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960894X24001112"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":69,"alternative-id":["S0960894X24001112"],"URL":"https:\/\/doi.org\/10.1016\/j.bmcl.2024.129709","relation":{},"ISSN":["0960-894X"],"issn-type":[{"value":"0960-894X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hydrazyl hydroxycoumarins as new potential conquerors towards Pseudomonas aeruginosa","name":"articletitle","label":"Article Title"},{"value":"Bioorganic & Medicinal Chemistry Letters","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bmcl.2024.129709","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"129709"}}