{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T17:12:34Z","timestamp":1779297154228,"version":"3.51.4"},"reference-count":38,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T00:00:00Z","timestamp":1772409600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["2021_GNT2011217"],"award-info":[{"award-number":["2021_GNT2011217"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004097","name":"Fondation ARC pour la Recherche sur Le Cancer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005189","name":"Leukemia and Lymphoma Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005189","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021839","name":"Snowdome Foundation","doi-asserted-by":"publisher","award":["6605-20"],"award-info":[{"award-number":["6605-20"]}],"id":[{"id":"10.13039\/501100021839","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004224","name":"Peter MacCallum Cancer Centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004224","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"Agence nationale de la recherche","doi-asserted-by":"publisher","award":["ANR-15-IDEX-01"],"award-info":[{"award-number":["ANR-15-IDEX-01"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004099","name":"La Ligue Contre Le Cancer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004099","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013371","name":"Universit\u00e9 C\u00f4te d\u2019Azur","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013371","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Blood Neoplasia"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.bneo.2026.100214","type":"journal-article","created":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T17:15:13Z","timestamp":1772471713000},"page":"100214","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Enhanced efficacy of a specific HDAC3 inhibitor in combination with 5-azacitidine against diffuse large B-cell lymphoma"],"prefix":"10.1016","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-8942-3062","authenticated-orcid":false,"given":"Calixte","family":"Calaud","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8003-4117","authenticated-orcid":false,"given":"Emilio M.","family":"Serrano-Lopez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8613-0508","authenticated-orcid":false,"given":"Leonie A.","family":"Cluse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9488-7508","authenticated-orcid":false,"given":"Izabela","family":"Todorovski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8636-8346","authenticated-orcid":false,"given":"Thomas","family":"Mardivirin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9415-1659","authenticated-orcid":false,"given":"Matt R.","family":"Teater","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-9331-3753","authenticated-orcid":false,"given":"Abdelillah","family":"Maarad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3331-2320","authenticated-orcid":false,"given":"Noura","family":"Tawfic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6955-4955","authenticated-orcid":false,"given":"Peter J.","family":"Fraser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Killian","family":"Guiraud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8115-9278","authenticated-orcid":false,"given":"Coralie","family":"Dupont","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6028-0281","authenticated-orcid":false,"given":"Corinne","family":"Menigot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0060-0594","authenticated-orcid":false,"given":"Ana Carolina B.","family":"Sant\u2019Anna-Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9591-1349","authenticated-orcid":false,"given":"David","family":"Yoannidis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4048-1553","authenticated-orcid":false,"given":"Tim","family":"Semple","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4349-1931","authenticated-orcid":false,"given":"Emeline","family":"Kerreneur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0943-1304","authenticated-orcid":false,"given":"St\u00e9phane","family":"Rocchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5062-8048","authenticated-orcid":false,"given":"Arnaud","family":"Jacquel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8074-2287","authenticated-orcid":false,"given":"Ari M.","family":"Melnick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7053-9237","authenticated-orcid":false,"given":"Ricky W.","family":"Johnstone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5775-4351","authenticated-orcid":false,"given":"Pilar M.","family":"Dominguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6769","key":"10.1016\/j.bneo.2026.100214_bib1","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1038\/35000501","article-title":"Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling","volume":"403","author":"Alizadeh","year":"2000","journal-title":"Nature"},{"issue":"7","key":"10.1016\/j.bneo.2026.100214_bib2","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1038\/s41375-022-01620-2","article-title":"The 5th edition of the World Health Organization classification of haematolymphoid tumours: lymphoid neoplasms","volume":"36","author":"Alaggio","year":"2022","journal-title":"Leukemia"},{"issue":"9","key":"10.1016\/j.bneo.2026.100214_bib3","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1056\/NEJMra2027612","article-title":"Diffuse large B-cell lymphoma","volume":"384","author":"Sehn","year":"2021","journal-title":"N Engl J Med"},{"issue":"16","key":"10.1016\/j.bneo.2026.100214_bib4","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1182\/blood-2017-03-769620","article-title":"Outcomes in refractory diffuse large B-cell lymphoma: results from the international SCHOLAR-1 study","volume":"130","author":"Crump","year":"2017","journal-title":"Blood"},{"issue":"12","key":"10.1016\/j.bneo.2026.100214_bib5","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1038\/s41408-020-00389-w","article-title":"Genetic and epigenetic determinants of diffuse large B-cell lymphoma","volume":"10","author":"Bakhshi","year":"2020","journal-title":"Blood Cancer J"},{"issue":"1","key":"10.1016\/j.bneo.2026.100214_bib6","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1111\/imr.12755","article-title":"Germinal center-derived lymphomas: the darkest side of humoral immunity","volume":"288","author":"Mlynarczyk","year":"2019","journal-title":"Immunol Rev"},{"issue":"8","key":"10.1016\/j.bneo.2026.100214_bib7","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1038\/s41571-019-0190-8","article-title":"Emerging epigenetic-modulating therapies in lymphoma","volume":"16","author":"Sermer","year":"2019","journal-title":"Nat Rev Clin Oncol"},{"issue":"9","key":"10.1016\/j.bneo.2026.100214_bib8","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1158\/2159-8290.CD-13-0117","article-title":"Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma","volume":"3","author":"Clozel","year":"2013","journal-title":"Cancer Discov"},{"issue":"8","key":"10.1016\/j.bneo.2026.100214_bib9","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1182\/blood.2021011679","article-title":"Phase 1 study of oral azacitidine (CC-486) plus R-CHOP in previously untreated intermediate- to high-risk DLBCL","volume":"139","author":"Martin","year":"2022","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.bneo.2026.100214_bib10","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s13148-023-01452-6","article-title":"Clinical advances in epigenetic therapies for lymphoma","volume":"15","author":"Rosenthal","year":"2023","journal-title":"Clin Epigenetics"},{"issue":"20","key":"10.1016\/j.bneo.2026.100214_bib11","doi-asserted-by":"crossref","first-page":"5506","DOI":"10.1182\/blood-2011-02-336891","article-title":"HDAC inhibitors and decitabine are highly synergistic and associated with unique gene-expression and epigenetic profiles in models of DLBCL","volume":"118","author":"Kalac","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.bneo.2026.100214_bib12","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/s13148-016-0245-y","article-title":"Combinatorial epigenetic therapy in diffuse large B cell lymphoma pre-clinical models and patients","volume":"8","author":"Pera","year":"2016","journal-title":"Clin Epigenetics"},{"issue":"34","key":"10.1016\/j.bneo.2026.100214_bib13","doi-asserted-by":"crossref","first-page":"19571","DOI":"10.1039\/C9RA02985K","article-title":"Next-generation of selective histone deacetylase inhibitors","volume":"9","author":"Yang","year":"2019","journal-title":"RSC Adv"},{"issue":"3","key":"10.1016\/j.bneo.2026.100214_bib14","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.celrep.2013.06.016","article-title":"A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters","volume":"4","author":"Hatzi","year":"2013","journal-title":"Cell Rep"},{"issue":"1","key":"10.1016\/j.bneo.2026.100214_bib15","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1158\/2159-8290.CD-16-0975","article-title":"CREBBP inactivation promotes the development of HDAC3-dependent lymphomas","volume":"7","author":"Jiang","year":"2017","journal-title":"Cancer Discov"},{"issue":"3","key":"10.1016\/j.bneo.2026.100214_bib16","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1158\/2159-8290.CD-16-1417","article-title":"The CREBBP acetyltransferase is a haploinsufficient tumor suppressor in B-cell lymphoma","volume":"7","author":"Zhang","year":"2017","journal-title":"Cancer Discov"},{"issue":"3","key":"10.1016\/j.bneo.2026.100214_bib17","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1158\/2159-8290.CD-19-0116","article-title":"Selective inhibition of HDAC3 targets synthetic vulnerabilities and activates immune surveillance in lymphoma","volume":"10","author":"Mondello","year":"2020","journal-title":"Cancer Discov"},{"issue":"12","key":"10.1016\/j.bneo.2026.100214_bib18","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1158\/2159-8290.CD-18-0657","article-title":"TET2 deficiency causes germinal center hyperplasia, impairs plasma cell differentiation and promotes B-cell lymphomagenesis","volume":"8","author":"Dominguez","year":"2018","journal-title":"Cancer Discov"},{"issue":"2","key":"10.1016\/j.bneo.2026.100214_bib19","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1021\/acschembio.5b00640","article-title":"An isochemogenic set of inhibitors to define the therapeutic potential of histone deacetylases in \u03b2-cell protection","volume":"11","author":"Wagner","year":"2016","journal-title":"ACS Chem Biol"},{"issue":"9","key":"10.1016\/j.bneo.2026.100214_bib20","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1158\/2159-8290.CD-13-0117","article-title":"Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma","volume":"3","author":"Clozel","year":"2013","journal-title":"Cancer Discov"},{"key":"10.1016\/j.bneo.2026.100214_bib21","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.imlet.2023.01.005","article-title":"The cellular biology of plasma cells: unmet challenges and opportunities","volume":"254","author":"Bonaud","year":"2023","journal-title":"Immunol Lett"},{"issue":"2","key":"10.1016\/j.bneo.2026.100214_bib22","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1182\/blood-2002-10-3161","article-title":"Gene expression profiling of plasma cells and plasmablasts: toward a better understanding of the late stages of B-cell differentiation","volume":"102","author":"Tarte","year":"2003","journal-title":"Blood"},{"issue":"6","key":"10.1016\/j.bneo.2026.100214_bib23","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1038\/ni.3154","article-title":"Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells","volume":"16","author":"Shi","year":"2015","journal-title":"Nat Immunol"},{"issue":"20","key":"10.1016\/j.bneo.2026.100214_bib24","doi-asserted-by":"crossref","first-page":"10934","DOI":"10.1093\/nar\/gkad841","article-title":"Expanding the coverage of regulons from high-confidence prior knowledge for accurate estimation of transcription factor activities","volume":"51","author":"Muller-Dott","year":"2023","journal-title":"Nucleic Acids Res"},{"issue":"12","key":"10.1016\/j.bneo.2026.100214_bib25","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.1038\/s41418-022-01037-5","article-title":"Epigenetic modulators of B cell fate identified through coupled phenotype-transcriptome analysis","volume":"29","author":"Kong","year":"2022","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.bneo.2026.100214_bib26","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/978-1-0716-3331-1_22","article-title":"MAC-seq: coupling low-cost, high-throughput RNA-seq with image-based phenotypic screening in 2D and 3D cell models","volume":"2691","author":"Li","year":"2023","journal-title":"Methods Mol Biol"},{"issue":"1","key":"10.1016\/j.bneo.2026.100214_bib27","doi-asserted-by":"crossref","first-page":"4307","DOI":"10.1038\/s41467-018-06500-x","article-title":"DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery","volume":"9","author":"Ye","year":"2018","journal-title":"Nat Commun"},{"issue":"11","key":"10.1016\/j.bneo.2026.100214_bib28","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1038\/nmeth.4463","article-title":"SCENIC: single-cell regulatory network inference and clustering","volume":"14","author":"Aibar","year":"2017","journal-title":"Nat Methods"},{"issue":"1","key":"10.1016\/j.bneo.2026.100214_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.esmoop.2022.100750","article-title":"How I treat diffuse large B-cell lymphoma","volume":"8","author":"Melchardt","year":"2023","journal-title":"ESMO Open"},{"issue":"1","key":"10.1016\/j.bneo.2026.100214_bib30","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1111\/imr.13012","article-title":"The special unfolded protein response in plasma cells","volume":"303","author":"Ricci","year":"2021","journal-title":"Immunol Rev"},{"issue":"1","key":"10.1016\/j.bneo.2026.100214_bib31","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1038\/s41392-023-01570-w","article-title":"Endoplasmic reticulum stress: molecular mechanism and therapeutic targets","volume":"8","author":"Chen","year":"2023","journal-title":"Signal Transduct Target Ther"},{"issue":"12","key":"10.1016\/j.bneo.2026.100214_bib32","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1038\/s41408-021-00584-3","article-title":"Differentiation therapy for myeloid malignancies: beyond cytotoxicity","volume":"11","author":"Stubbins","year":"2021","journal-title":"Blood Cancer J"},{"issue":"9","key":"10.1016\/j.bneo.2026.100214_bib33","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1182\/blood-2013-03-488114","article-title":"Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors","volume":"123","author":"Bots","year":"2014","journal-title":"Blood"},{"issue":"6","key":"10.1016\/j.bneo.2026.100214_bib34","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1158\/2159-8290.CD-20-1145","article-title":"Epigenetic activation of plasmacytoid DCs drives IFNAR-dependent therapeutic differentiation of AML","volume":"12","author":"Salmon","year":"2022","journal-title":"Cancer Discov"},{"issue":"16","key":"10.1016\/j.bneo.2026.100214_bib35","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1182\/blood.2024025500","article-title":"Targeting DOT1L and EZH2 synergizes in breaking the germinal center identity of diffuse large B-cell lymphoma","volume":"145","author":"Gobel","year":"2025","journal-title":"Blood"},{"issue":"24","key":"10.1016\/j.bneo.2026.100214_bib36","doi-asserted-by":"crossref","first-page":"2873","DOI":"10.1182\/blood.2024026534","article-title":"Synergistic antitumor effect of combined EZH2 and DOT1L inhibition in B-cell lymphoma","volume":"145","author":"Nguyen","year":"2025","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.bneo.2026.100214_bib37","first-page":"186","article-title":"Hypomethylating agent decitabine sensitizes diffuse large B-cell lymphoma to venetoclax","volume":"109","author":"Zhu","year":"2024","journal-title":"Haematologica"},{"issue":"3","key":"10.1016\/j.bneo.2026.100214_bib38","doi-asserted-by":"crossref","first-page":"229","DOI":"10.4161\/epi.5.3.11409","article-title":"5-azacytidine treatment reorganizes genomic histone modification patterns","volume":"5","author":"Komashko","year":"2010","journal-title":"Epigenetics"}],"container-title":["Blood Neoplasia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2950328026000257?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2950328026000257?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T16:24:04Z","timestamp":1779294244000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2950328026000257"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":38,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S2950328026000257"],"URL":"https:\/\/doi.org\/10.1016\/j.bneo.2026.100214","relation":{},"ISSN":["2950-3280"],"issn-type":[{"value":"2950-3280","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Enhanced efficacy of a specific HDAC3 inhibitor in combination with 5-azacitidine against diffuse large B-cell lymphoma","name":"articletitle","label":"Article Title"},{"value":"Blood Neoplasia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bneo.2026.100214","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 American Society of Hematology. Published by Elsevier Inc. Licensed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0), permitting only noncommercial, nonderivative use with attribution. All other rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"100214"}}