{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T23:12:14Z","timestamp":1784243534903,"version":"3.55.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2004,7,1]],"date-time":"2004-07-01T00:00:00Z","timestamp":1088640000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bone"],"published-print":{"date-parts":[[2004,7]]},"DOI":"10.1016\/j.bone.2004.02.016","type":"journal-article","created":{"date-parts":[[2004,6,21]],"date-time":"2004-06-21T19:51:08Z","timestamp":1087847468000},"page":"320-325","source":"Crossref","is-referenced-by-count":39,"title":["The mineralization index\u2014A new approach to the histomorphometric appraisal of osteomalacia"],"prefix":"10.1016","volume":"35","author":[{"given":"A.M.","family":"Parfitt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shijing","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.S.","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bone.2004.02.016_BIB1","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/S0002-9343(99)00460-X","article-title":"Osteomalacia due to vitamin D depletion: a neglected consequence of intestinal malabsorption","volume":"108","author":"Basha","year":"2000","journal-title":"Am. J. Med."},{"key":"10.1016\/j.bone.2004.02.016_BIB2","series-title":"Osteoporosis","first-page":"501","article-title":"Clinical use of bone biopsy","author":"Chavassieux","year":"2001"},{"key":"10.1016\/j.bone.2004.02.016_BIB3","series-title":"Vitamin D.","first-page":"573","article-title":"Bone Histomorphometry","author":"Compston","year":"1997"},{"key":"10.1016\/j.bone.2004.02.016_BIB4","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1093\/clinchem\/45.9.1548","article-title":"Aluminum, iron, lead, cadmium, copper, zinc, chromium, magnesium, strontium, and calcium content in bone of end-stage renal failure patients","volume":"45","author":"D'Haese","year":"1999","journal-title":"Clin. Chem."},{"key":"10.1016\/j.bone.2004.02.016_BIB5","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1359\/jbmr.2002.17.12.2094","article-title":"Pathophysiology and recent advances in the management of renal osteodystrophy","volume":"17","author":"Elder","year":"2002","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2004.02.016_BIB6","series-title":"Handbook of Experimental Pharmacology","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/978-3-642-77991-6_2","article-title":"Bone remodeling and bone structure","volume":"vol. 107","author":"Eriksen","year":"1993"},{"key":"10.1016\/j.bone.2004.02.016_BIB7","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1002\/jbmr.5650111219","article-title":"Effect of ethnicity and age or menopause on the structure and geometry of iliac bone","volume":"11","author":"Han","year":"1996","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2004.02.016_BIB8","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1359\/jbmr.1997.12.4.498","article-title":"Effects of ethnicity and age or menopause on the remodeling and turnover of iliac bone: implications for mechanisms of bone loss","volume":"12","author":"Han","year":"1997","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2004.02.016_BIB9","first-page":"123","article-title":"A discriminant function for the biochemical diagnosis of osteomalacia in elderly subjects and its relevance to interpretation of borderline bone histological findings","volume":"2","author":"Hodkinson","year":"1980","journal-title":"J. Clin. Exp. Gerontol."},{"key":"10.1016\/j.bone.2004.02.016_BIB10","doi-asserted-by":"crossref","first-page":":949","DOI":"10.3928\/0147-7447-19890701-07","article-title":"Quantitative computed tomography reflects vertebral fracture morbidity in osteopenic patients","volume":"12","author":"Kaplan","year":"1989","journal-title":"Orthopedics"},{"key":"10.1016\/j.bone.2004.02.016_BIB11","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/BF01625446","article-title":"A randomized trial of sodium fluoride as a treatment for postmenopausal osteoporosis","volume":"1","author":"Kleerekoper","year":"1991","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2004.02.016_BIB12","series-title":"Metabolic Bone Disease and Clinically Related Disorders","first-page":"387","article-title":"Osteoporosis pathogenesis and therapy","author":"Kleerekoper","year":"1998"},{"key":"10.1016\/j.bone.2004.02.016_BIB13","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1002\/jbmr.5650020617","article-title":"Bone histomorphometry nomenclature, symbols and units. Report of the ASBMR Histomorphometry Nomenclature Committee","volume":"2","author":"Parfitt","year":"1987","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2004.02.016_BIB14","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1359\/jbmr.1997.12.11.1864","article-title":"Effects of ethnicity and age or menopause on osteoblast function, bone mineralization and osteoid accumulation in iliac bone","volume":"12","author":"Parfitt","year":"1997","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2004.02.016_BIB15","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1093\/ajcn\/36.5.1014","article-title":"Vitamin D and bone health in the elderly","volume":"36","author":"Parfitt","year":"1982","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.bone.2004.02.016_BIB16","doi-asserted-by":"crossref","first-page":":387","DOI":"10.1097\/00041552-200307000-00007","article-title":"Renal bone disease\u2014A new conceptual framework for the interpretation of bone histomorphometry","volume":"12","author":"Parfitt","year":"2003","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"key":"10.1016\/j.bone.2004.02.016_BIB17","first-page":"3","article-title":"The cellular mechanisms of osteoid accumulation in metabolic bone disease","volume":"vol. 4","author":"Parfitt","year":"1984"},{"key":"10.1016\/j.bone.2004.02.016_BIB18","series-title":"Phosphate and Mineral Homeostasis","first-page":"283","article-title":"Comparison of aluminum related with vitamin D related osteomalacia by tetracycline based bone histomorphometry","volume":"vol. 208","author":"Parfitt","year":"1986"},{"key":"10.1016\/j.bone.2004.02.016_BIB19","series-title":"Nutritional aspects of osteoporosis","first-page":"197","article-title":"The evolution of vitamin d related bone disease: the importance of an early stage of increased bone turnover without impaired mineralization","author":"Parfitt","year":"2001"},{"key":"10.1016\/j.bone.2004.02.016_BIB20","series-title":"Bone histomorphometry. Techniques and interpretations","first-page":"143","article-title":"The physiologic and clinical significance of bone histomorphometric data","author":"Parfitt","year":"1983"},{"key":"10.1016\/j.bone.2004.02.016_BIB21","series-title":"Metabolic bone disease and clinically related disorders","first-page":"327","article-title":"Osteomalacia and related disorders","author":"Parfitt","year":"1998"},{"key":"10.1016\/j.bone.2004.02.016_BIB22","series-title":"Disorders of bone and mineral metabolism","first-page":"469","article-title":"The physiologic and pathogenetic significance of bone histomorphometric data","author":"Parfitt","year":"2002"},{"key":"10.1016\/j.bone.2004.02.016_BIB23","unstructured":"Parfitt,AM (200). Vitamin D and the pathogenesis of rickets and osteomalacia. In: Feldman D, Glorieux F, Pike W (eds). Vitamin D, Second ed. Academic Press, San Diego CA (in press)."},{"key":"10.1016\/j.bone.2004.02.016_BIB24","series-title":"Clinical disorders of bone and mineral metabolism","first-page":"209","article-title":"Osteoclastic resorption of osteoid in secondary hyperparathyroidism","author":"Qiu","year":"1983"},{"key":"10.1016\/j.bone.2004.02.016_BIB25","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1359\/jbmr.2003.18.9.1657","article-title":"Reduced iliac cancellous osteocyte density in patients with osteoporotic vertebral fracture","volume":"18","author":"Qui","year":"2003","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2004.02.016_BIB26","series-title":"Clinical disorders of bone and mineral metabolism","first-page":"224","article-title":"Histologic evolution of vitamin D depletion in patients with intestinal malabsorption or dietary deficiency","author":"Rao","year":"1983"},{"key":"10.1016\/j.bone.2004.02.016_BIB27","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1681\/ASN.V971225","article-title":"Mineralized bone loss at different sites in dialysis patients: implications for prevention","volume":"9","author":"Schober","year":"1998","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.bone.2004.02.016_BIB28","series-title":"Studying a study and testing a test, how to read the medical evidence","author":"Riegelman","year":"2000"},{"key":"10.1016\/j.bone.2004.02.016_BIB29","first-page":"1","article-title":"Nutritional osteomalacia (metabolic aspects with particular reference to serum vitamin D activity)","volume":"65","author":"Teotia","year":"1975","journal-title":"J. Indian Med. Assoc."},{"key":"10.1016\/j.bone.2004.02.016_BIB30","series-title":"Disorders of bone and mineral metabolism","first-page":"448","article-title":"Clinical use of bone biopsy","author":"Weinstein","year":"2002"}],"container-title":["Bone"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328204000857?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328204000857?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,6,23]],"date-time":"2021-06-23T15:19:45Z","timestamp":1624461585000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S8756328204000857"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,7]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,7]]}},"alternative-id":["S8756328204000857"],"URL":"https:\/\/doi.org\/10.1016\/j.bone.2004.02.016","relation":{},"ISSN":["8756-3282"],"issn-type":[{"value":"8756-3282","type":"print"}],"subject":[],"published":{"date-parts":[[2004,7]]}}}