{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T22:40:14Z","timestamp":1790980814588,"version":"4.1.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["17390416"],"award-info":[{"award-number":["17390416"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["17591563"],"award-info":[{"award-number":["17591563"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bone"],"published-print":{"date-parts":[[2007,2]]},"DOI":"10.1016\/j.bone.2006.09.019","type":"journal-article","created":{"date-parts":[[2006,10,28]],"date-time":"2006-10-28T07:19:00Z","timestamp":1162019940000},"page":"522-528","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":111,"title":["Transplantation of culture expanded bone marrow cells and platelet rich plasma in distraction osteogenesis of the long bones"],"prefix":"10.1016","volume":"40","author":[{"given":"Hiroshi","family":"Kitoh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiko","family":"Kitakoji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Tsuchiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuyasu","family":"Katoh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Ishiguro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bone.2006.09.019_bib1","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1126\/science.284.5411.143","article-title":"Multilineage potential of adult human mesenchymal stem cells","volume":"284","author":"Pittenger","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.bone.2006.09.019_bib2","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0278-2391(00)90058-2","article-title":"Quantification of growth factor levels using a simplified method of platelet-rich plasma gel preparation","volume":"58","author":"Landesberg","year":"2000","journal-title":"J. Oral Maxillofac. Surg."},{"key":"10.1016\/j.bone.2006.09.019_bib3","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1002\/jor.20112","article-title":"In vitro study on the healing of bone defects treated with bone marrow stromal cells, platelet-rich plasma, and freeze-dried bone allografts, alone and in combination","volume":"24","author":"Dallari","year":"2006","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.bone.2006.09.019_bib4","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1097\/01.blo.0000165736.87628.12","article-title":"Stromal stem cells and platelet-rich plasma improve bone allograft integration","volume":"435","author":"Lucarelli","year":"2005","journal-title":"Clin. Orthop."},{"key":"10.1016\/j.bone.2006.09.019_bib5","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1097\/00003086-200206000-00029","article-title":"Distraction osteogenesis enhanced by osteoblast-like cells and collagen gel","volume":"399","author":"Takamine","year":"2002","journal-title":"Clin. Orthop."},{"key":"10.1016\/j.bone.2006.09.019_bib6","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/j.bone.2004.06.013","article-title":"Transplantation of marrow-derived mesenchymal stem cells and platelet-rich plasma during distraction osteogenesis\u2014A preliminary result of three cases","volume":"35","author":"Kitoh","year":"2004","journal-title":"Bone"},{"key":"10.1016\/j.bone.2006.09.019_bib7","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/S1079-2104(98)90029-4","article-title":"Platelet-rich plasma: growth factor enhancement for bone grafts","volume":"85","author":"Marx","year":"1998","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endo."},{"key":"10.1016\/j.bone.2006.09.019_bib8","doi-asserted-by":"crossref","first-page":"624","DOI":"10.2106\/00004623-199905000-00004","article-title":"Distraction osteogenesis for lengthening of the tibia in patients who have limb-length discrepancy or short stature","volume":"81-A","author":"Aldegheri","year":"1999","journal-title":"J. Bone Joint Surg."},{"key":"10.1016\/j.bone.2006.09.019_bib9","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1097\/01241398-200307000-00012","article-title":"Effect of pulsed electromagnetic field stimulation on distraction osteogenesis in the rabbit tibial leg lengthening model","volume":"23","author":"Fredericks","year":"2003","journal-title":"J. Pediatr. Orthop."},{"key":"10.1016\/j.bone.2006.09.019_bib10","first-page":"165","article-title":"Effect of hyperbaric oxygenation treatment on lengthened callus","volume":"26","author":"Kitakoji","year":"1999","journal-title":"Undersea Hyperb. Med."},{"key":"10.1016\/j.bone.2006.09.019_bib11","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/S0736-0266(03)00181-5","article-title":"Effects of timing of low pulsed ultrasound on distraction osteogenesis","volume":"22","author":"Sakurakichi","year":"2003","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.bone.2006.09.019_bib12","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S8756-3282(98)00158-6","article-title":"Recombinant growth hormone accelerates bone regenerate consolidation in distraction osteogenesis","volume":"24","author":"Raschke","year":"1999","journal-title":"Bone"},{"key":"10.1016\/j.bone.2006.09.019_bib13","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1097\/00003086-199406000-00034","article-title":"Bone mineral density of lengthened rabbit tibia is enhanced by transplantation of fresh autologous bone marrow cells","volume":"303","author":"Hamanishi","year":"1994","journal-title":"Clin. Orthop."},{"key":"10.1016\/j.bone.2006.09.019_bib14","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/S0736-0266(01)00166-8","article-title":"Bone consolidation is enhanced by rhBMP-2 in a rabbit model of distraction osteogenesis","volume":"20","author":"Li","year":"2002","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.bone.2006.09.019_bib15","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1006\/jsre.1998.5378","article-title":"Osteogenic potential of cultured periosteal cells in a distracted bone gap in rabbits","volume":"78","author":"Takushima","year":"1998","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.bone.2006.09.019_bib16","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.bbrc.2004.02.038","article-title":"Osteogenic potential of rat mesenchymal stem cells after several passages","volume":"316","author":"Sugiura","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bone.2006.09.019_bib17","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0278-2391(00)90058-2","article-title":"Quantification of growth factor levels using a simplified method of platelet-rich plasma gel preparation","volume":"58","author":"Landesberg","year":"2000","journal-title":"J. Oral Maxillofac. Surg."},{"key":"10.1016\/j.bone.2006.09.019_bib18","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.orthres.2004.08.015","article-title":"Autologous preparations rich in growth factors promote proliferation and induce VEGF and HGF production by human tendon cells in culture","volume":"23","author":"Anitua","year":"2005","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.bone.2006.09.019_bib19","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1054\/ijom.2003.0492","article-title":"Influence of platelet rich plasma (PRP) on osteogenic differentiation of rat bone marrow stromal cells. An in vitro study","volume":"33","author":"Arpornmaeklong","year":"2004","journal-title":"Int. J. Oral Maxillofac. Surg."},{"key":"10.1016\/j.bone.2006.09.019_bib20","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.tripleo.2005.03.007","article-title":"The effect of platelet-rich plasma on the cellular response of rat bone marrow cells in vitro","volume":"100","author":"Ogino","year":"2005","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endo."},{"key":"10.1016\/j.bone.2006.09.019_bib21","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.ijom.2004.10.018","article-title":"Effect of platelet-rich plasma (PRP) concentration on the viability and proliferation of alveolar bone cells: an in vitro study","volume":"34","author":"Choi","year":"2005","journal-title":"Int. J. Oral Maxillofac. Surg."},{"key":"10.1016\/j.bone.2006.09.019_bib22","doi-asserted-by":"crossref","first-page":"3095","DOI":"10.1016\/S0142-9612(03)00114-5","article-title":"Platelet-derived growth factors enhance proliferation of human stromal cells","volume":"24","author":"Lucarelli","year":"2003","journal-title":"Biomaterials"},{"key":"10.1016\/j.bone.2006.09.019_bib23","doi-asserted-by":"crossref","first-page":"18","DOI":"10.2106\/00004623-199801000-00005","article-title":"Complications of limb-lengthening in children who have an underlying bone disorder","volume":"80-A","author":"Naudie","year":"1998","journal-title":"J. Bone Joint Surg."},{"key":"10.1016\/j.bone.2006.09.019_bib24","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1097\/00003086-199001000-00011","article-title":"Problems, obstacles, and complications of limb lengthening by Illizarov technique","volume":"250","author":"Paley","year":"1990","journal-title":"Clin. Orthop."},{"key":"10.1016\/j.bone.2006.09.019_bib25","doi-asserted-by":"crossref","first-page":"793","DOI":"10.2106\/00004623-199806000-00003","article-title":"Distraction osteogenesis of the lower extremity with use of monolateral external fixation\u2014A study of two hundred and sixty-one femora and tibiae","volume":"80-A","author":"Noonan","year":"1998","journal-title":"J. Bone Joint Surg."},{"key":"10.1016\/j.bone.2006.09.019_bib26","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1097\/00003086-199404000-00006","article-title":"Variables affecting time to bone healing during distraction limb lengthening","volume":"301","author":"Fischgrund","year":"1994","journal-title":"Clin. Orthop."},{"key":"10.1016\/j.bone.2006.09.019_bib27","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1097\/01241398-200209000-00015","article-title":"Radiographic assessment of bone formation in tibia during distraction osteogenesis","volume":"22","author":"Donnan","year":"2002","journal-title":"J. Pediatr. Orthop."},{"key":"10.1016\/j.bone.2006.09.019_bib28","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/j.bone.2003.06.002","article-title":"Expression of angiogenic factors during distraction osteogenesis","volume":"33","author":"Pacicca","year":"2003","journal-title":"Bone"},{"key":"10.1016\/j.bone.2006.09.019_bib29","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1359\/JBMR.050301","article-title":"Angiogenesis is required for successful bone induction during distraction osteogenesis","volume":"20","author":"Fang","year":"2005","journal-title":"J. Bone Miner. Res."}],"container-title":["Bone"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S875632820600737X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S875632820600737X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T17:32:28Z","timestamp":1757611948000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S875632820600737X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,2]]}},"alternative-id":["S875632820600737X"],"URL":"https:\/\/doi.org\/10.1016\/j.bone.2006.09.019","relation":{},"ISSN":["8756-3282"],"issn-type":[{"value":"8756-3282","type":"print"}],"subject":[],"published":{"date-parts":[[2007,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transplantation of culture expanded bone marrow cells and platelet rich plasma in distraction osteogenesis of the long bones","name":"articletitle","label":"Article Title"},{"value":"Bone","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bone.2006.09.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}