{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:01:36Z","timestamp":1791356496414,"version":"4.3.1"},"reference-count":42,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bone"],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1016\/j.bone.2011.11.012","type":"journal-article","created":{"date-parts":[[2011,12,7]],"date-time":"2011-12-07T08:19:57Z","timestamp":1323245997000},"page":"224-231","source":"Crossref","is-referenced-by-count":14,"title":["Serum xylosyltransferase 1 level increases during early posttraumatic osteoarthritis in mice with high bone forming potential"],"prefix":"10.1016","volume":"51","author":[{"given":"Sarah Y.","family":"McCoy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerry A.","family":"Falgowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Padma P.","family":"Srinivasan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William R.","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica M.","family":"Selva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine B.","family":"Kirn-Safran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bone.2011.11.012_bb0005","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1097\/01.bot.0000246468.80635.ef","article-title":"Posttraumatic osteoarthritis: a first estimate of incidence, prevalence, and burden of disease","volume":"20","author":"Brown","year":"2006","journal-title":"J Orthop Trauma"},{"key":"10.1016\/j.bone.2011.11.012_bb0010","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.joca.2007.03.006","article-title":"The surgical destabilization of the medial meniscus (DMM) model of osteoarthritis in the 129\/SvEv mouse","volume":"15","author":"Glasson","year":"2007","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.bone.2011.11.012_bb0015","doi-asserted-by":"crossref","first-page":"R14","DOI":"10.1186\/ar2604","article-title":"The retinoic acid binding protein CRABP2 is increased in murine models of degenerative joint disease","volume":"11","author":"Welch","year":"2009","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.bone.2011.11.012_bb0020","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1136\/ard.2009.124586","article-title":"Inhibition of bone resorption blunts osteoarthritis in mice with high bone remodelling","volume":"69","author":"Kadri","year":"2010","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.bone.2011.11.012_bb0025","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.pmrj.2011.05.009","article-title":"Anabolic\/catabolic balance in pathogenesis of osteoarthritis: identifying molecular targets","volume":"3","author":"Mueller","year":"2011","journal-title":"Pm R"},{"key":"10.1016\/j.bone.2011.11.012_bb0030","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1002\/1529-0131(200003)43:3<664::AID-ANR24>3.0.CO;2-D","article-title":"Comparison of the degradation of type II collagen and proteoglycan in nasal and articular cartilages induced by interleukin-1 and the selective inhibition of type II collagen cleavage by collagenase","volume":"43","author":"Billinghurst","year":"2000","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.bone.2011.11.012_bb0035","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1172\/JCI119316","article-title":"Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage","volume":"99","author":"Billinghurst","year":"1997","journal-title":"J Clin Invest"},{"key":"10.1016\/j.bone.2011.11.012_bb0040","doi-asserted-by":"crossref","first-page":"2613","DOI":"10.1002\/art.10576","article-title":"Uncoupling of type II collagen synthesis and degradation predicts progression of joint damage in patients with knee osteoarthritis","volume":"46","author":"Garnero","year":"2002","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.bone.2011.11.012_bb0045","doi-asserted-by":"crossref","first-page":"2268","DOI":"10.1172\/JCI116113","article-title":"Studies of the articular cartilage proteoglycan aggrecan in health and osteoarthritis. Evidence for molecular heterogeneity and extensive molecular changes in disease","volume":"90","author":"Rizkalla","year":"1992","journal-title":"J Clin Invest"},{"key":"10.1016\/j.bone.2011.11.012_bb0050","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1096\/fj.08-118166","article-title":"Modulation of xylosyltransferase I expression provides a mechanism regulating glycosaminoglycan chain synthesis during cartilage destruction and repair","volume":"23","author":"Venkatesan","year":"2009","journal-title":"FASEB J"},{"key":"10.1016\/j.bone.2011.11.012_bb0055","doi-asserted-by":"crossref","first-page":"2252","DOI":"10.1634\/stemcells.2005-0508","article-title":"The formation of extracellular matrix during chondrogenic differentiation of mesenchymal stem cells correlates with increased levels of xylosyltransferase I","volume":"24","author":"Prante","year":"2006","journal-title":"Stem Cells"},{"key":"10.1016\/j.bone.2011.11.012_bb0060","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1046\/j.1523-1747.1999.00590.x","article-title":"Serum xylosyltransferase: a new biochemical marker of the sclerotic process in systemic sclerosis","volume":"112","author":"Gotting","year":"1999","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.bone.2011.11.012_bb0065","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.joca.2005.11.004","article-title":"Mutational and functional analyses of xylosyltransferases and their implication in osteoarthritis","volume":"14","author":"Schon","year":"2006","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.bone.2011.11.012_bb0070","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/j.bone.2004.05.013","article-title":"In vivo and in vitro evidence that the high osteoblastic activity in C3H\/HeJ mice compared to C57BL\/6J mice is intrinsic to bone cells","volume":"35","author":"Sheng","year":"2004","journal-title":"Bone"},{"key":"10.1016\/j.bone.2011.11.012_bb0215","series-title":"Handbook of histology methods for bone and cartilage","first-page":"209","article-title":"Histological techniques for decalcified bone and cartilage","author":"Kang","year":"2003"},{"key":"10.1016\/j.bone.2011.11.012_bb0080","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.joca.2005.07.014","article-title":"Osteoarthritis cartilage histopathology: grading and staging","volume":"14","author":"Pritzker","year":"2006","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.bone.2011.11.012_bb0085","series-title":"Handbook of biological statistics","author":"McDonald","year":"2009"},{"key":"10.1016\/j.bone.2011.11.012_bb0090","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.1016\/j.joca.2010.05.027","article-title":"Recommendations for the use of preclinical models in the study and treatment of osteoarthritis","volume":"18","author":"Poole","year":"2010","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.bone.2011.11.012_bb0095","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s00774-003-0432-8","article-title":"Lower bone cellular activities in male and female mature C3H\/HeJ mice are associated with higher bone mass and different pyridinium crosslink profiles compared to C57BL\/6J mice","volume":"21","author":"Amblard","year":"2003","journal-title":"J Bone Miner Metab"},{"key":"10.1016\/j.bone.2011.11.012_bb0100","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1359\/JBMR.050707","article-title":"Genetic variation in bone growth patterns defines adult mouse bone fragility","volume":"20","author":"Price","year":"2005","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.bone.2011.11.012_bb0105","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.bone.2005.05.001","article-title":"Bone mineral density and vertebral fracture history are associated with incident and progressive radiographic knee osteoarthritis in elderly men and women: the Rotterdam Study","volume":"37","author":"Bergink","year":"2005","journal-title":"Bone"},{"key":"10.1016\/j.bone.2011.11.012_bb0110","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1016\/j.joca.2008.04.012","article-title":"A pilot study of the reproducibility and validity of measuring knee subchondral bone density in the tibia","volume":"16","author":"Dore","year":"2008","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.bone.2011.11.012_bb0115","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S8756-3282(03)00059-0","article-title":"Subchondral tibial bone mineral density predicts future joint space narrowing at the medial femoro-tibial compartment in patients with knee osteoarthritis","volume":"32","author":"Bruyere","year":"2003","journal-title":"Bone"},{"key":"10.1016\/j.bone.2011.11.012_bb0120","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/ard.52.8.557","article-title":"Prediction of the progression of joint space narrowing in osteoarthritis of the knee by bone scintigraphy","volume":"52","author":"Dieppe","year":"1993","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.bone.2011.11.012_bb0220","first-page":"34","article-title":"Role of subchondral bone in the initiation and progression of cartilage damage","author":"Radin","year":"1986","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.bone.2011.11.012_bb0130","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1359\/jbmr.2003.18.3.561","article-title":"Tail suspension induces bone loss in skeletally mature mice in the C57BL\/6J strain but not in the C3H\/HeJ strain","volume":"18","author":"Amblard","year":"2003","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.bone.2011.11.012_bb0135","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/S8756-3282(02)00871-2","article-title":"Mechanotransduction in bone: genetic effects on mechanosensitivity in mice","volume":"31","author":"Robling","year":"2002","journal-title":"Bone"},{"key":"10.1016\/j.bone.2011.11.012_bb0140","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1111\/j.1749-6632.2009.05240.x","article-title":"Articular cartilage and subchondral bone in the pathogenesis of osteoarthritis","volume":"1192","author":"Goldring","year":"2010","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.bone.2011.11.012_bb0145","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.matbio.2007.09.005","article-title":"Increased levels of xylosyltransferase I correlate with the mineralization of the extracellular matrix during osteogenic differentiation of mesenchymal stem cells","volume":"27","author":"Muller","year":"2008","journal-title":"Matrix Biol"},{"key":"10.1016\/j.bone.2011.11.012_bb0150","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s10719-008-9180-2","article-title":"High xylosyltransferase activity in children and during mineralization of osteoblast-like SAOS-2 cells","volume":"26","author":"Prante","year":"2009","journal-title":"Glycoconj J"},{"key":"10.1016\/j.bone.2011.11.012_bb0155","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/ar630","article-title":"Aggrecanases and cartilage matrix degradation","volume":"5","author":"Nagase","year":"2003","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.bone.2011.11.012_bb0160","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1016\/j.joca.2008.03.008","article-title":"Changes in synovial fluid and serum biomarkers with exercise and early osteoarthritis in horses","volume":"16","author":"Frisbie","year":"2008","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.bone.2011.11.012_bb0165","doi-asserted-by":"crossref","first-page":"R229","DOI":"10.1186\/ar3216","article-title":"Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254)","volume":"12","author":"Catterall","year":"2010","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.bone.2011.11.012_bb0170","series-title":"Changes in serum biomarkers of cartilage turnover following ACL reconstruction","author":"Svoboda","year":"2010"},{"key":"10.1016\/j.bone.2011.11.012_bb0175","doi-asserted-by":"crossref","first-page":"3452","DOI":"10.1002\/art.11355","volume":"48","author":"Clements","year":"2003","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.bone.2011.11.012_bb0180","doi-asserted-by":"crossref","first-page":"14224","DOI":"10.1074\/jbc.M510690200","article-title":"Cloning and recombinant expression of active full-length xylosyltransferase I (XT-I) and characterization of subcellular localization of XT-I and XT-II","volume":"281","author":"Schon","year":"2006","journal-title":"J Biol Chem"},{"key":"10.1016\/j.bone.2011.11.012_bb0185","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.bbrc.2009.08.038","article-title":"Articular cartilage vesicles contain RNA","volume":"388","author":"Mitton","year":"2009","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.bone.2011.11.012_bb0190","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1016\/j.bone.2005.02.013","article-title":"Loading induces site-specific increases in mineral content assessed by microcomputed tomography of the mouse tibia","volume":"36","author":"Fritton","year":"2005","journal-title":"Bone"},{"key":"10.1016\/j.bone.2011.11.012_bb0195","doi-asserted-by":"crossref","first-page":"R102","DOI":"10.1186\/ar2494","article-title":"Biochemical markers of bone turnover and their association with bone marrow lesions","volume":"10","author":"Hunter","year":"2008","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.bone.2011.11.012_bb0200","doi-asserted-by":"crossref","first-page":"R50","DOI":"10.1186\/ar3293","article-title":"The role of synovial fluid markers of catabolism and anabolism in osteoarthritis, rheumatoid arthritis and asymptomatic organ donors","volume":"13","author":"Kokebie","year":"2011","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.bone.2011.11.012_bb0205","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1359\/jbmr.2001.16.2.386","article-title":"Postnatal and pubertal skeletal changes contribute predominantly to the differences in peak bone density between C3H\/HeJ and C57BL\/6J mice","volume":"16","author":"Richman","year":"2001","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.bone.2011.11.012_bb0210","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1186\/ar3135","article-title":"Bone and cartilage in osteoarthritis: is what's best for one good or bad for the other?","volume":"12","author":"Goldring","year":"2010","journal-title":"Arthritis Res Ther"}],"container-title":["Bone"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328211013512?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328211013512?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T22:59:57Z","timestamp":1543359597000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S8756328211013512"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":42,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["S8756328211013512"],"URL":"https:\/\/doi.org\/10.1016\/j.bone.2011.11.012","relation":{},"ISSN":["8756-3282"],"issn-type":[{"value":"8756-3282","type":"print"}],"subject":[],"published":{"date-parts":[[2012,8]]}}}