{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T17:03:24Z","timestamp":1791565404399,"version":"4.3.4"},"reference-count":72,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Ministry of Higher Education","award":["CEOR\/001-08"],"award-info":[{"award-number":["CEOR\/001-08"]}]},{"name":"Ministry of Higher Education","award":["CEOR\/004-08"],"award-info":[{"award-number":["CEOR\/004-08"]}]},{"name":"Ministry of Higher Education","award":["CEOR\/019-09"],"award-info":[{"award-number":["CEOR\/019-09"]}]}],"content-domain":{"domain":["thebonejournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bone"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1016\/j.bone.2013.06.029","type":"journal-article","created":{"date-parts":[[2013,7,9]],"date-time":"2013-07-09T03:15:26Z","timestamp":1373339726000},"page":"355-362","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":153,"title":["Increased serum sclerostin and decreased serum IGF-1 are associated with vertebral fractures among postmenopausal women with type-2 diabetes"],"prefix":"10.1016","volume":"56","author":[{"given":"Mohammed-Salleh M.","family":"Ardawi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daad H.","family":"Akhbar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulrahman","family":"AlShaikh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maimoona M.","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed H.","family":"Qari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulrahim A.","family":"Rouzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed Y.","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adel A.","family":"Abdulrafee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamdouh Y.","family":"Saeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bone.2013.06.029_bb0005","doi-asserted-by":"crossref","first-page":"3404","DOI":"10.1210\/jc.2006-0614","article-title":"Risk of fracture in women with type 2 diabetes: the women's health initiative observational study","volume":"91","author":"Bonds","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.bone.2013.06.029_bb0010","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s00198-006-0253-4","article-title":"Discrepancies in bone and mineral density and fracture risk in patients with type 1 and type 2 diabetes \u2014 a meta-analysis","volume":"18","author":"Vestergaard","year":"2007","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.bone.2013.06.029_bb0015","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.bone.2008.03.017","article-title":"Diabetes and fragility fractures: a burgeoning epidemic?","volume":"43","author":"Epstein","year":"2008","journal-title":"Bone"},{"key":"10.1016\/j.bone.2013.06.029_bb0020","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1002\/jbmr.556","article-title":"FRAX underestimates fracture risk in patients with diabetes","volume":"27","author":"Giangregorio","year":"2012","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.bone.2013.06.029_bb0025","doi-asserted-by":"crossref","first-page":"2184","DOI":"10.1001\/jama.2011.715","volume":"305","author":"Schwartz","year":"2011","journal-title":"JAMA"},{"key":"10.1016\/j.bone.2013.06.029_bb0365","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/2045-3701-2-28","article-title":"The involvement of the wnt signaling pathway and TCF7L2 in diabetes mellitus: the current understanding, dispute, and perspective","volume":"2","author":"Ip","year":"2012","journal-title":"Cell & Bioscience"},{"key":"10.1016\/j.bone.2013.06.029_bb0035","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.devcel.2005.03.016","article-title":"Wnt\/\u03b2-catenin in mesencymal progenitor's controls osteoblast and chondrocyte differentiation during vertebrae skeletogenesis","volume":"8","author":"Day","year":"2005","journal-title":"Dev Cell"},{"key":"10.1016\/j.bone.2013.06.029_bb0040","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1101\/gad.1388806","article-title":"Smad3-dependent nuclear translocation of \u03b2-catenin is required for TGF-\u03b21 induced proliferation of bone marrow- derived adult human mesenchymal stem cells","volume":"20","author":"Jian","year":"2006","journal-title":"Genes Dev"},{"key":"10.1016\/j.bone.2013.06.029_bb0045","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s12011-012-9333-9","article-title":"The influence of fluoride on the expression of inhibitors of Wnt\/\u03b2-catenin signaling pathway in rat skin fibroblast cells","volume":"148","author":"Liu","year":"2012","journal-title":"Biol Trace Elem Res"},{"key":"10.1016\/j.bone.2013.06.029_bb0050","doi-asserted-by":"crossref","first-page":"19883","DOI":"10.1074\/jbc.M413274200","article-title":"Sclerostin binds to LRP5\/6 and antagonizes canonical Wnt signaling","volume":"280","author":"Li","year":"2005","journal-title":"J Biol Chem"},{"key":"10.1016\/j.bone.2013.06.029_bb0055","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1086\/318811","article-title":"Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein","volume":"68","author":"Brunkow","year":"2001","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.bone.2013.06.029_bb0060","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1093\/hmg\/10.5.537","article-title":"Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)","volume":"10","author":"Balemans","year":"2001","journal-title":"Hum Mol Genet"},{"issue":"4","key":"10.1016\/j.bone.2013.06.029_bb0065","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1359\/jbmr.081206","article-title":"Sclerostin antibody treatment increases bone formation, bone mass and bone strength in a rat model of postmenopausal osteoporosis","volume":"24","author":"Li","year":"2009","journal-title":"J Bone Miner Res"},{"issue":"5","key":"10.1016\/j.bone.2013.06.029_bb0070","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1002\/jbmr.14","article-title":"Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength","volume":"25","author":"Ominsky","year":"2010","journal-title":"J Bone Miner Res"},{"issue":"1","key":"10.1016\/j.bone.2013.06.029_bb0075","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/jbmr.173","article-title":"Single-dose, placebo-controlled, randomized study of AMG785, a sclerostin monoclonal antibody","volume":"26","author":"Padhi","year":"2011","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.bone.2013.06.029_bb0080","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.tem.2008.08.004","article-title":"Wnt signaling: relevance to \u03b2-cell biology and diabetes","volume":"19","author":"Welters","year":"2008","journal-title":"Trends Endocrinol Metab"},{"key":"10.1016\/j.bone.2013.06.029_bb0085","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1086\/425340","article-title":"Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes","volume":"75","author":"Kanazawa","year":"2004","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.bone.2013.06.029_bb0090","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1530\/EJE-11-1061","article-title":"Distinct effects of pioglitazone and metformin on circulating sclerostin and biochemical markers of bone turnover in men with type 2 diabetes mellitus","volume":"166","author":"van Lierop","year":"2012","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.bone.2013.06.029_bb0095","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1210\/jc.2011-2958","article-title":"Circulating sclerostin levels and bone turnover in type 1 and type 2 diabetes","volume":"97","author":"Gennari","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.bone.2013.06.029_bb0100","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.2174\/1381612043383764","article-title":"The anabolic effects of GH\/IGF system on bone","volume":"10","author":"Kasukawa","year":"2005","journal-title":"Curr Pharm Des"},{"key":"10.1016\/j.bone.2013.06.029_bb0105","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.gene.2005.07.016","article-title":"The insulin-like growth factor-1 gene and osteoporosis: a critical appraisal","volume":"361","author":"Niu","year":"2005","journal-title":"Gene"},{"key":"10.1016\/j.bone.2013.06.029_bb0110","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1016\/S0140-6736(99)05463-X","article-title":"Low serum IGF-1 and occurrence of osteoporotic fractures in postmenopausal women","volume":"355","author":"Garnero","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.bone.2013.06.029_bb0115","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1359\/jbmr.1997.12.8.1272","article-title":"Serum levels of insulin-like growth factor (IGF) 1, IGF-binding protein (IGFBP)-2, and IGFBP-3 in osteoporotic patients with and without spinal fractures","volume":"12","author":"Sugimoto","year":"1997","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.bone.2013.06.029_bb0120","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/s00223-005-0163-z","article-title":"Serum levels of insulin-like growth factor (IGF); IGF-binding proteins-3, -4 and -5; and their relationships to bone mineral density and the risk of vertebral fractures in postmenopausal women","volume":"78","author":"Yamaguchi","year":"2006","journal-title":"Calcif Tissue Int"},{"key":"10.1016\/j.bone.2013.06.029_bb0125","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1007\/s00198-007-0430-0","article-title":"Serum insulin-like growth factor-1 is associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes mellitus","volume":"18","author":"Kanazawa","year":"2007","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.bone.2013.06.029_bb0130","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1007\/s00198-010-1310-6","article-title":"Serum insulin-like growth factor-1 is a marker for assessing the severity of vertebral fractures in postmenopausal women with type 2 diabetes mellitus","volume":"22","author":"Kanazawa","year":"2011","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.bone.2013.06.029_bb0135","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1007\/s00198-008-0744-6","article-title":"Morphometric vertebral fractures of the lower thoracic and lumbar spine, physical function and quality of life in men","volume":"20","author":"Pasco","year":"2009","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.bone.2013.06.029_bb0140","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/S0140-6736(98)09075-8","article-title":"Mortality after all major types of osteoporotic fracture in men and women: an observational study","volume":"353","author":"Center","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.bone.2013.06.029_bb0145","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1007\/s001980070075","article-title":"Risk of mortality following clinical fractures","volume":"11","author":"Cauley","year":"2000","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.bone.2013.06.029_bb0150","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/S8756-3282(03)00241-2","article-title":"Severity of prevalent vertebral fractures and the risk of subsequent vertebral and nonvertebral fractures: results from the MORE trial","volume":"33","author":"Delmas","year":"2003","journal-title":"Bone"},{"key":"10.1016\/j.bone.2013.06.029_bb0155","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0002-9343(99)00028-5","article-title":"The association between low bone mass at the menopause and cardiovascular mortality","volume":"106","author":"von der Recke","year":"1999","journal-title":"Am J Med"},{"key":"10.1016\/j.bone.2013.06.029_bb0160","doi-asserted-by":"crossref","first-page":"S37","DOI":"10.2337\/diacare.28.suppl_1.S37","article-title":"Diagnosis and classification of diabetes mellitus","volume":"28","author":"American Diabetes Association","year":"2005","journal-title":"Diabetes Care"},{"key":"10.1016\/j.bone.2013.06.029_bb0165","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1016\/0002-8703(86)90022-0","article-title":"Assessment methods for physical activity and physical fitness in population studies: report of a NHLBI workshop","volume":"111","author":"Wilson","year":"1986","journal-title":"Am Heart J"},{"issue":"12","key":"10.1016\/j.bone.2013.06.029_bb0170","doi-asserted-by":"crossref","first-page":"2812","DOI":"10.1002\/jbmr.479","article-title":"Determinants of serum sclerostin in healthy pre- and postmenopausal women","volume":"26","author":"Ardawi","year":"2011","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.bone.2013.06.029_bb0175","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1002\/jbmr.5650110716","article-title":"Comparison of semiquantitative visual and quantitative morphometric assessment of prevalent and incident vertebral fractures in osteoporosis. The Study of Osteoporotic Fractures Research Group","volume":"11","author":"Genant","year":"2006","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.bone.2013.06.029_bb0180","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1007\/s00198-008-0832-7","article-title":"Spinal deformity index (SDI) is a good predictor of incident vertebral fractures","volume":"20","author":"Kerkeni","year":"2009","journal-title":"Osteoporos Int"},{"issue":"1","key":"10.1016\/j.bone.2013.06.029_bb0185","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1002\/jbmr.128","article-title":"Regulation of circulating sclerostin levels by sex steroids in women and men","volume":"26","author":"Modder","year":"2011","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.bone.2013.06.029_bb0190","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/j.bone.2010.07.017","article-title":"Reference intervals of biochemical bone turnover markers for Saudi Arabian women: a cross-sectional study","volume":"47","author":"Ardawi","year":"2010","journal-title":"Bone"},{"key":"10.1016\/j.bone.2013.06.029_bb0195","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1210\/jcem.86.1.7139","article-title":"Older women with diabetes have an increased risk of fracture: a prospective study","volume":"86","author":"Schwartz","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.bone.2013.06.029_bb0200","first-page":"68","article-title":"Osteoporosis and osteoporotic fractures in postmenopausal women with type 2 diabetic compared with non-diabetic cases","volume":"4","author":"Mobini","year":"2012","journal-title":"Iran J Diab Obes"},{"key":"10.1016\/j.bone.2013.06.029_bb0205","article-title":"Type 2 diabetes is associated with vertebral fractures in a sample of clinic- and hospital-based Latinos","author":"Kilpadi","year":"2013","journal-title":"J Immigr Minor Health"},{"key":"10.1016\/j.bone.2013.06.029_bb0210","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s00774-012-0398-5","article-title":"The prevalence and risk factors of vertebral fractures in Korean patients with type 2 diabetes","volume":"31","author":"Chung","year":"2013","journal-title":"J Bone Miner Metab"},{"key":"10.1016\/j.bone.2013.06.029_bb0215","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1359\/jbmr.081207","article-title":"Diabetic patients have an increased risk of vertebral fractures independent of BMD or diabetic complications","volume":"24","author":"Yamamoto","year":"2009","journal-title":"J Bone Miner Res"},{"issue":"3","key":"10.1016\/j.bone.2013.06.029_bb0220","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1210\/jc.2007-1270","article-title":"Serum pentosidine levels are positively associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes","volume":"93","author":"Yamamoto","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.bone.2013.06.029_bb0225","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s00198-008-0657-4","article-title":"The prevalence of radiographic vertebral fractures in Latin American countries: the Latin American vertebral osteoporosis study (LAVOS)","volume":"20","author":"Clark","year":"2009","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.bone.2013.06.029_bb0230","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1007\/s12020-012-9848-z","article-title":"Spinal deformity index in patients with type 2 diabetes","volume":"43","author":"Di Somma","year":"2013","journal-title":"Endocrine"},{"key":"10.1016\/j.bone.2013.06.029_bb0370","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1210\/jc.2011-2186","article-title":"Circulating levels of sclerostin are increased in patients with type 2 diabetes mellitus","volume":"97","author":"Garcia-Martin","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.bone.2013.06.029_bb0240","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1530\/EJE-11-1061","article-title":"Distinct effects of pioglitazone and metformin on circulating sclerostin and biochemical markers of bone turnover in menwith type 2 diabetes mellitus","volume":"166","author":"van Lierop","year":"2012","journal-title":"Eur J Endocrinol"},{"issue":"10","key":"10.1016\/j.bone.2013.06.029_bb0245","doi-asserted-by":"crossref","first-page":"3744","DOI":"10.1210\/jc.2012-1901","article-title":"Sclerostin levels associated with inhibition of the Wnt\/\u03b2-catenin signaling and reduced bone turnover in type 2 diabetes mellitus","volume":"97","author":"Gaudio","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.bone.2013.06.029_bb0250","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1210\/jc.2011-2537","article-title":"Decreased PTH levels accompanied by low bone formation are associated with vertebral fractures in postmenopausal women with type 2 diabetes","volume":"97","author":"Yamamoto","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.bone.2013.06.029_bb0255","doi-asserted-by":"crossref","first-page":"2804","DOI":"10.1002\/jbmr.474","article-title":"Patients with sclerosteosis and disease carriers: human models of the effect of sclerostin on bone turnover","volume":"26","author":"van Lierop","year":"2011","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.bone.2013.06.029_bb0260","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1359\/jbmr.090411","article-title":"Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt\/\u03b2-catenin signaling","volume":"24","author":"Lin","year":"2009","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.bone.2013.06.029_bb0265","doi-asserted-by":"crossref","first-page":"2248","DOI":"10.1210\/jc.2010-0067","article-title":"Increased sclerostin serum levels associated with bone formation and resorption markers in patients with immobilization-induced bone loss","volume":"95","author":"Gaudio","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.bone.2013.06.029_bb0270","doi-asserted-by":"crossref","first-page":"5056","DOI":"10.1210\/jc.2010-0720","article-title":"Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women","volume":"95","author":"Drake","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.bone.2013.06.029_bb0275","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1210\/jc.2011-1534","article-title":"Acute decline in serum sclerostin in response to PTH infusion in healthy men","volume":"96","author":"Yu","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.bone.2013.06.029_bb0280","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1002\/jbmr.217","article-title":"Relation of age, gender and bone mass to circulating sclerostin levels in women and men","volume":"26","author":"Modder","year":"2011","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.bone.2013.06.029_bb0285","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.ghir.2004.06.002","article-title":"Bone metabolism is relation to alterations in systemic growth hormone","volume":"14","author":"Ueland","year":"2004","journal-title":"Growth Horm IGF Res"},{"key":"10.1016\/j.bone.2013.06.029_bb0290","doi-asserted-by":"crossref","first-page":"277","DOI":"10.3109\/03008208909023897","article-title":"Insulin-like growth factor (IGF) and bone","volume":"20","author":"McCarthy","year":"1989","journal-title":"Connect Tissue Res"},{"key":"10.1016\/j.bone.2013.06.029_bb0295","first-page":"67","article-title":"Insulin-like growth factor binding proteins in bone cell regulation","volume":"3","author":"Mohan","year":"1993","journal-title":"Growth Regul"},{"key":"10.1016\/j.bone.2013.06.029_bb0300","doi-asserted-by":"crossref","first-page":"44005","DOI":"10.1074\/jbc.M208265200","article-title":"Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals and essential role of IGF signaling in bone matrix mineralization","volume":"277","author":"Zhang","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1016\/j.bone.2013.06.029_bb0305","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1007\/s00198-006-0155-5","article-title":"Role of collagen enzymatic and glycation induced cross-links as a determinant of bone quality in spontaneously diabetic WBN\/Kob rats","volume":"17","author":"Saito","year":"2006","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.bone.2013.06.029_bb0310","doi-asserted-by":"crossref","first-page":"4139","DOI":"10.1210\/jcem.86.9.7868","article-title":"Association of IGF-1 levels with muscle strength and mobility in older women","volume":"86","author":"Cappola","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.bone.2013.06.029_bb0315","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1007\/s00198-005-2023-0","article-title":"The severity of vertebral fractures and health-related quality of life in osteoporotic postmenopausal women","volume":"16","author":"Fechtenbaum","year":"2005","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.bone.2013.06.029_bb0375","first-page":"569","article-title":"NIH Consensus Development Panel on Osteoporosis Prevention, Diagnosis, Therapy2001 Osteoporosis prevention, diagnosis, and therapy, March 7\u201329: highlights of the conference","volume":"94","year":"2000","journal-title":"South Med J"},{"key":"10.1016\/j.bone.2013.06.029_bb0325","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1007\/s00198-005-1877-5","article-title":"Increased bone density and decreased bone turnover, but no evident alteration of fracture susceptibility in elderly women with diabetes mellitus","volume":"16","author":"Gerdhem","year":"2005","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.bone.2013.06.029_bb0330","doi-asserted-by":"crossref","first-page":"477","DOI":"10.2337\/diab.39.4.477","article-title":"Bone and mineral metabolism in BB rats with long-term diabetes. Decreased bone turnover and osteoporosis","volume":"39","author":"Verhaeghe","year":"1990","journal-title":"Diabetes"},{"key":"10.1016\/j.bone.2013.06.029_bb0335","first-page":"1315","article-title":"Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications","volume":"318","author":"Brownlee","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1016\/j.bone.2013.06.029_bb0340","first-page":"160","article-title":"Age-related changes in the collagen crosslinking in the femoral neck cancellous bone in cases of hip fracture and controls","volume":"79","author":"Wang","year":"2002","journal-title":"Calcif Tissue Int"},{"key":"10.1016\/j.bone.2013.06.029_bb0345","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1007\/s00223-006-0035-1","article-title":"Degree of mineralization-related collagen crosslinking in the femoral neck cancellous bone in cases of hip fracture and controls","volume":"79","author":"Saito","year":"2006","journal-title":"Calcif Tissue Int"},{"key":"10.1016\/j.bone.2013.06.029_bb0350","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1007\/s00223-003-0023-7","article-title":"Diabetes mellitus: does it affect bone?","volume":"73","author":"Schwartz","year":"2003","journal-title":"Calcif Tissue Int"},{"key":"10.1016\/j.bone.2013.06.029_bb0355","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.2337\/diacare.23.9.1272","article-title":"Diabetes and physical disability among older U.S. adults","volume":"23","author":"Gregg","year":"2000","journal-title":"Diabetes Care"},{"key":"10.1016\/j.bone.2013.06.029_bb0360","doi-asserted-by":"crossref","first-page":"E1159","DOI":"10.1210\/jc.2011-0254","article-title":"Determination of serum and plasma sclerostin concentrations by enzyme-linked immunoassays","volume":"96","author":"McNulty","year":"2011","journal-title":"J Clin Endocrinol Metab"}],"container-title":["Bone"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328213002470?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328213002470?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T17:51:15Z","timestamp":1588960275000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S8756328213002470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":72,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["S8756328213002470"],"URL":"https:\/\/doi.org\/10.1016\/j.bone.2013.06.029","relation":{},"ISSN":["8756-3282"],"issn-type":[{"value":"8756-3282","type":"print"}],"subject":[],"published":{"date-parts":[[2013,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Increased serum sclerostin and decreased serum IGF-1 are associated with vertebral fractures among postmenopausal women with type-2 diabetes","name":"articletitle","label":"Article Title"},{"value":"Bone","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bone.2013.06.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}