{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T14:37:12Z","timestamp":1788878232694,"version":"build-2803163510"},"reference-count":37,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["30672702"],"award-info":[{"award-number":["30672702"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["30873276"],"award-info":[{"award-number":["30873276"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81273770"],"award-info":[{"award-number":["81273770"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Key Program of Traditional Chinese Medicine of Zhejiang Province, China","award":["2005Z003"],"award-info":[{"award-number":["2005Z003"]}]}],"content-domain":{"domain":["thebonejournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bone"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1016\/j.bone.2013.08.022","type":"journal-article","created":{"date-parts":[[2013,8,29]],"date-time":"2013-08-29T10:01:22Z","timestamp":1377770482000},"page":"509-516","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":70,"title":["The efficacy of targeted intraarterial delivery of concentrated autologous bone marrow containing mononuclear cells in the treatment of osteonecrosis of the femoral head: A five year follow-up study"],"prefix":"10.1016","volume":"57","author":[{"given":"Qiang","family":"Mao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongting","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luwei","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peijian","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bone.2013.08.022_bb0005","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1002\/jor.20802","article-title":"Distribution of TRAP-positive cells and expression of HIF-1alpha, VEGF, and FGF-2 in the reparative reaction in patients with osteonecrosis of the femoral head","volume":"27","author":"Li","year":"2009","journal-title":"J Orthop Res"},{"key":"10.1016\/j.bone.2013.08.022_bb0010","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1007\/s10067-008-0861-9","article-title":"The use of bisphosphonate in the treatment of avascular necrosis: a systematic review","volume":"27","author":"Cardozo","year":"2008","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.bone.2013.08.022_bb0015","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/s11999-011-2050-4","article-title":"Which factors influence preservation of the osteonecrotic femoral head?","volume":"470","author":"Lieberman","year":"2012","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.bone.2013.08.022_bb0020","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1007\/s10067-009-1231-y","article-title":"The use of extracorporeal shock waves in the treatment of osteonecrosis of the femoral head: a systematic review","volume":"28","author":"Alves","year":"2009","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.bone.2013.08.022_bb0025","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s00264-010-0979-7","article-title":"Osteonecrosis is not a predictor of poor outcomes in primary total hip arthroplasty: a systematic literature review","volume":"35","author":"Johannson","year":"2011","journal-title":"Int Orthop"},{"issue":"Suppl. 4","key":"10.1016\/j.bone.2013.08.022_bb0030","doi-asserted-by":"crossref","first-page":"175","DOI":"10.2106\/JBJS.H.00671","article-title":"Treatment of early stage osteonecrosis of the femoral head","volume":"90","author":"Marker","year":"2008","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.bone.2013.08.022_bb0035","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1002\/jor.20759","article-title":"Fate of mesenchymal stem cells transplanted to osteonecrosis of femoral head","volume":"27","author":"Yan","year":"2009","journal-title":"J Orthop Res"},{"key":"10.1016\/j.bone.2013.08.022_bb0040","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1097\/BTO.0b013e3181690814","article-title":"Bone marrow injection in hip osteonecrosis","volume":"23","author":"Hernigou","year":"2008","journal-title":"Tech Orthop"},{"key":"10.1016\/j.bone.2013.08.022_bb0045","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1038\/gt.2008.110","article-title":"Treatment of avascular necrosis of the femoral head by hepatocyte growth factor-transgenic bone marrow stromal stem cells","volume":"15","author":"Wen","year":"2008","journal-title":"Gene Ther"},{"key":"10.1016\/j.bone.2013.08.022_bb0050","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.bone.2011.11.002","article-title":"Treatment of early stage osteonecrosis of the femoral head with autologous implantation of bone marrow-derived and cultured mesenchymal stem cells","volume":"50","author":"Zhao","year":"2012","journal-title":"Bone"},{"key":"10.1016\/j.bone.2013.08.022_bb0055","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1007\/s00264-010-1009-5","article-title":"Cytotherapy of osteonecrosis of the femoral head: a mini review","volume":"34","author":"Gao","year":"2010","journal-title":"Int Orthop"},{"key":"10.1016\/j.bone.2013.08.022_bb0060","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/j.bone.2011.07.032","article-title":"Autologous bone marrow cell implantation in the treatment of non-traumatic osteonecrosis of the femoral head: five year follow-up of a prospective controlled study","volume":"49","author":"Gangji","year":"2011","journal-title":"Bone"},{"key":"10.1016\/j.bone.2013.08.022_bb0065","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1007\/s00402-009-0939-0","article-title":"Treatment of nontraumatic osteonecrosis of the femoral head with the implantation of core decompression and concentrated autologous bone marrow containing mononuclear cells","volume":"130","author":"Wang","year":"2010","journal-title":"Arch Orthop Trauma Surg"},{"key":"10.1016\/j.bone.2013.08.022_bb0070","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1586\/ehm.09.60","article-title":"Autologous hematopoietic stem cell transplantation in autoimmune diseases","volume":"2","author":"Annaloro","year":"2009","journal-title":"Expert Rev Hematol"},{"key":"10.1016\/j.bone.2013.08.022_bb0075","first-page":"251","article-title":"Current strategies for the treatment of autoimmune diseases","volume":"24","author":"Rosato","year":"2010","journal-title":"J Biol Regul Homeost Agents"},{"key":"10.1016\/j.bone.2013.08.022_bb0080","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1001\/archneurol.2010.248","article-title":"Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosis","volume":"67","author":"Karussis","year":"2010","journal-title":"Arch Neurol"},{"key":"10.1016\/j.bone.2013.08.022_bb0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/03009740903030324","article-title":"Autologous stem cell transplantation in autoimmune and rheumatic diseases: from the molecular background to clinical applications","volume":"39","author":"Szodoray","year":"2010","journal-title":"Scand J Rheumatol"},{"key":"10.1016\/j.bone.2013.08.022_bb0090","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.ejheart.2008.03.017","article-title":"Transplantation of adipose derived stromal cells is associated with functional improvement in a rat model of chronic myocardial infarction","volume":"10","author":"Mazo","year":"2008","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.bone.2013.08.022_bb0095","doi-asserted-by":"crossref","first-page":"313","DOI":"10.3727\/096368909X480323","article-title":"Transplantation of mesenchymal stem cells exerts a greater long-term effect than bone marrow mononuclear cells in a chronic myocardial infarction model in rat","volume":"19","author":"Mazo","year":"2010","journal-title":"Cell Transplant"},{"key":"10.1016\/j.bone.2013.08.022_bb0100","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1097\/SLA.0b013e3181f4e479","article-title":"Stem cell mobilization is life saving in an animal model of acute liver failure","volume":"252","author":"Mark","year":"2010","journal-title":"Ann Surg"},{"key":"10.1016\/j.bone.2013.08.022_bb0105","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.expneurol.2010.07.005","article-title":"Intravenous multipotent adult progenitor cell therapy for traumatic brain injury: pre-serving the blood brain barrier via an interaction with splenocytes","volume":"225","author":"Walker","year":"2010","journal-title":"Exp Neurol"},{"issue":"5","key":"10.1016\/j.bone.2013.08.022_bb0110","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1161\/STROKEAHA.107.502047","article-title":"Dual-modality monitoring of targeted intraarterial delivery of mesenchymal stem cells after transient ischemia","volume":"39","author":"Walczak","year":"2008","journal-title":"Stroke"},{"key":"10.1016\/j.bone.2013.08.022_bb0115","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1302\/0301-620X.67B1.3155745","article-title":"Idiopathic bone necrosis of femoral head. Early diagnosis and treatment","volume":"67","author":"Ficat","year":"1985","journal-title":"J Bone Joint Surg Br"},{"key":"10.1016\/j.bone.2013.08.022_bb0120","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/00003086-199204000-00015","article-title":"Free vascularized fibula grafting for the treatment of osteonecrosis of the femoral head","volume":"277","author":"Yoo","year":"1992","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.bone.2013.08.022_bb0125","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/00003086-199711000-00024","article-title":"Free vascularized fibula grafting for the treatment of osteonecrosis of the femoral head","volume":"344","author":"Sotereanos","year":"1997","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.bone.2013.08.022_bb0130","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1302\/0301-620X.91B8.21518","article-title":"The use of alendronate in the treatment of avascular necrosis of the femoral head: follow-up to eight years","volume":"91","author":"Agarwala","year":"2009","journal-title":"J Bone Joint Surg Br"},{"key":"10.1016\/j.bone.2013.08.022_bb0135","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.bone.2009.09.001","article-title":"Decreased in the number and function of circulation endothelial progenitor cells in patients with avascular necrosis of the femoral head","volume":"46","author":"Feng","year":"2010","journal-title":"Bone"},{"key":"10.1016\/j.bone.2013.08.022_bb0140","doi-asserted-by":"crossref","first-page":"2665","DOI":"10.1007\/s11999-010-1738-1","article-title":"Treatment of precollapse osteonecrosis using stem cells and growth factors","volume":"469","author":"Cui","year":"2011","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.bone.2013.08.022_bb0145","doi-asserted-by":"crossref","first-page":"74","DOI":"10.7150\/ijms.8.74","article-title":"Intravenous transplantation of allogeneic bone marrow mesenchymal stem cells and its directional migration to the necrotic femoral head","volume":"8","author":"Li","year":"2011","journal-title":"Int J Med Sci"},{"key":"10.1016\/j.bone.2013.08.022_bb0150","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1302\/0301-620X.47B4.612","article-title":"Idiopathic necrosis of the femoral head in adults","volume":"47","author":"Merle D'Aubign\u00e9","year":"1965","journal-title":"J Bone Joint Surg Br"},{"key":"10.1016\/j.bone.2013.08.022_bb0155","doi-asserted-by":"crossref","first-page":"267","DOI":"10.2106\/00004623-196446020-00004","article-title":"Idiopathic necrosis of the head of femur: a study of fifty-two cases","volume":"46","author":"Patterson","year":"1964","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.bone.2013.08.022_bb0160","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.2106\/JBJS.D.02959","article-title":"The use of alendronate to prevent early collapse of femoral head in patients with non traumatic osteonecrosis: a randomized clinical study","volume":"87","author":"Lai","year":"2005","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.bone.2013.08.022_bb0165","doi-asserted-by":"crossref","first-page":"459","DOI":"10.2106\/00004623-199503000-00018","article-title":"Non-traumatic avascular necrosis of the femoral head","volume":"77-A","author":"Mont","year":"1995","journal-title":"J Bone Joint Surg Am"},{"key":"10.1016\/j.bone.2013.08.022_bb0170","doi-asserted-by":"crossref","first-page":"S46","DOI":"10.1016\/j.bone.2007.04.050","article-title":"Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow cells: five- year follow-up","volume":"40","author":"Gangji","year":"2007","journal-title":"Bone"},{"key":"10.1016\/j.bone.2013.08.022_bb0175","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1089\/scd.2006.15.349","article-title":"Ex vivo expansion and in vivo infusion of bone marrow-derived Flk-1+CD31-CD34- mesenchymal stem cells: feasibility and safety from monkey to human","volume":"15","author":"Liu","year":"2006","journal-title":"Stem Cells Dev"},{"key":"10.1016\/j.bone.2013.08.022_bb0180","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1634\/stemcells.2007-0197","article-title":"Concise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homing","volume":"25","author":"Chamberlain","year":"2007","journal-title":"Stem Cells"},{"key":"10.1016\/j.bone.2013.08.022_bb0185","doi-asserted-by":"crossref","first-page":"667","DOI":"10.3727\/096368910X508762","article-title":"Mesenchymal stem cells: mechanisms of immunomodulation and homing","volume":"19","author":"Yagi","year":"2010","journal-title":"Cell Transplant"}],"container-title":["Bone"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328213003372?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328213003372?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T02:52:35Z","timestamp":1646448755000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S8756328213003372"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["S8756328213003372"],"URL":"https:\/\/doi.org\/10.1016\/j.bone.2013.08.022","relation":{},"ISSN":["8756-3282"],"issn-type":[{"value":"8756-3282","type":"print"}],"subject":[],"published":{"date-parts":[[2013,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The efficacy of targeted intraarterial delivery of concentrated autologous bone marrow containing mononuclear cells in the treatment of osteonecrosis of the femoral head: A five year follow-up study","name":"articletitle","label":"Article Title"},{"value":"Bone","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bone.2013.08.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}