{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:05:22Z","timestamp":1792098322981,"version":"4.4.0"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Korea Health Technology R&D Project, Ministry of Health & Welfare, Republic of Korea","award":["HI13C1432"],"award-info":[{"award-number":["HI13C1432"]}]},{"name":"Korea Health Technology R&D Project, Ministry of Health & Welfare, Republic of Korea","award":["HI14C2258"],"award-info":[{"award-number":["HI14C2258"]}]},{"name":"Takeda Pharmaceuticals Korea Co., Ltd., Seoul, Republic of Korea"}],"content-domain":{"domain":["clinicalkey.jp","thebonejournal.com","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bone"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.bone.2015.08.014","type":"journal-article","created":{"date-parts":[[2015,8,18]],"date-time":"2015-08-18T21:47:01Z","timestamp":1439934421000},"page":"435-441","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"special_numbering":"C","title":["Plasma periostin associates significantly with non-vertebral but not vertebral fractures in postmenopausal women: Clinical evidence for the different effects of periostin depending on the skeletal site"],"prefix":"10.1016","volume":"81","author":[{"given":"Beom-Jun","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumie","family":"Rhee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chong Hwa","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki Hyun","family":"Baek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Ki","family":"Min","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deog-Yoon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong Hee","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyeonmok","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Hun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun-Young","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moo-Il","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung-Min","family":"Koh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bone.2015.08.014_bb0005","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1007\/s00774-011-0280-x","article-title":"Burden of osteoporosis in adults in Korea: a national health insurance database study","volume":"30","author":"Choi","year":"2012","journal-title":"J. Bone Miner. Metab."},{"issue":"Suppl. 1","key":"10.1016\/j.bone.2015.08.014_bb0010","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/8756-3282(93)90341-7","article-title":"Hip fractures: a worldwide problem today and tomorrow","volume":"14","author":"Melton","year":"1993","journal-title":"Bone"},{"key":"10.1016\/j.bone.2015.08.014_bb0015","doi-asserted-by":"crossref","first-page":"17","DOI":"10.11005\/jbm.2013.20.1.17","article-title":"National healthcare budget impact analysis of the treatment for osteoporosis and fractures in Korea","volume":"20","author":"Yi","year":"2013","journal-title":"J. Bone Metab."},{"key":"10.1016\/j.bone.2015.08.014_bb0020","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1001\/jama.285.6.785","article-title":"Osteoporosis prevention, diagnosis, and therapy","volume":"285","year":"2001","journal-title":"JAMA"},{"key":"10.1016\/j.bone.2015.08.014_bb0025","doi-asserted-by":"crossref","first-page":"2787","DOI":"10.1210\/jc.2004-1568","article-title":"Hip fracture in women without osteoporosis","volume":"90","author":"Wainwright","year":"2005","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.bone.2015.08.014_bb0030","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.bone.2005.06.004","article-title":"Half the burden of fragility fractures in the community occur in women without osteoporosis. When is fracture prevention cost-effective?","volume":"38","author":"Sanders","year":"2006","journal-title":"Bone"},{"key":"10.1016\/j.bone.2015.08.014_bb0035","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/s00198-007-0543-5","article-title":"FRAX and the assessment of fracture probability in men and women from the UK","volume":"19","author":"Kanis","year":"2008","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2015.08.014_bb0040","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1007\/s00198-008-0712-1","article-title":"Case finding for the management of osteoporosis with FRAX \u2014 assessment and intervention thresholds for the UK","volume":"19","author":"Kanis","year":"2008","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2015.08.014_bb0045","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1002\/jbmr.215","article-title":"Evaluation of the FRAX and Garvan fracture risk calculators in older women","volume":"26","author":"Bolland","year":"2011","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2015.08.014_bb0050","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1002\/jbmr.12","article-title":"Fracture risk prediction using BMD and clinical risk factors in early postmenopausal women: sensitivity of the WHO FRAX tool","volume":"25","author":"Tremollieres","year":"2010","journal-title":"J. Bone Miner. Res."},{"issue":"Pt 1","key":"10.1016\/j.bone.2015.08.014_bb0055","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1042\/bj2940271","article-title":"Osteoblast-specific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I","volume":"294","author":"Takeshita","year":"1993","journal-title":"Biochem. J."},{"key":"10.1016\/j.bone.2015.08.014_bb0060","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1359\/jbmr.1999.14.7.1239","article-title":"Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor beta","volume":"14","author":"Horiuchi","year":"1999","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2015.08.014_bb0065","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.humpath.2008.07.008","article-title":"Periostin, a novel marker of intramembranous ossification, is expressed in fibrous dysplasia and in c-Fos-overexpressing bone lesions","volume":"40","author":"Kashima","year":"2009","journal-title":"Hum. Pathol."},{"key":"10.1016\/j.bone.2015.08.014_bb0070","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1007\/s00198-011-1892-7","article-title":"The multiple facets of periostin in bone metabolism","volume":"23","author":"Merle","year":"2012","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2015.08.014_bb0075","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1002\/jcb.20115","article-title":"Expression and function of periostin-isoforms in bone","volume":"92","author":"Litvin","year":"2004","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.bone.2015.08.014_bb0080","doi-asserted-by":"crossref","first-page":"35939","DOI":"10.1074\/jbc.M109.060335","article-title":"The matricellular protein periostin is required for Sost inhibition and the anabolic response to mechanical loading and physical activity","volume":"284","author":"Bonnet","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bone.2015.08.014_bb0085","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.bone.2014.10.011","article-title":"Periostin expression contributes to cortical bone loss during unloading","volume":"71","author":"Gerbaix","year":"2015","journal-title":"Bone"},{"key":"10.1016\/j.bone.2015.08.014_bb0090","doi-asserted-by":"crossref","first-page":"15048","DOI":"10.1073\/pnas.1203085109","article-title":"Regulation of beta catenin signaling and parathyroid hormone anabolic effects in bone by the matricellular protein periostin","volume":"109","author":"Bonnet","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bone.2015.08.014_bb0095","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1210\/jc.2013-3893","article-title":"Serum periostin is associated with fracture risk in postmenopausal women: a 7-year prospective analysis of the OFELY study","volume":"99","author":"Rousseau","year":"2014","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.bone.2015.08.014_bb0100","first-page":"113","article-title":"Osteophyte formation in the vertebral column: a review of the etiologic factors \u2014 Part II","volume":"29","author":"Nathan","year":"1994","journal-title":"Contemp. Orthop."},{"key":"10.1016\/j.bone.2015.08.014_bb0105","first-page":"518","article-title":"Assessing vertebral fractures. National Osteoporosis Foundation Working Group on Vertebral Fractures","volume":"10","author":"Kiel","year":"1995","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2015.08.014_bb0110","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1002\/jbmr.5650080915","article-title":"Vertebral fracture assessment using a semiquantitative technique","volume":"8","author":"Genant","year":"1993","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2015.08.014_bb0115","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1159\/000180580","article-title":"Prediction of creatinine clearance from serum creatinine","volume":"16","author":"Cockcroft","year":"1976","journal-title":"Nephron"},{"key":"10.1016\/j.bone.2015.08.014_bb0120","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0078347","article-title":"Periostin deficiency increases bone damage and impairs injury response to fatigue loading in adult mice","volume":"8","author":"Bonnet","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.bone.2015.08.014_bb0125","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.orthres.2003.10.007","article-title":"Gene expression of periostin in the early stage of fracture healing detected by cDNA microarray analysis","volume":"22","author":"Nakazawa","year":"2004","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.bone.2015.08.014_bb0130","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1359\/JBMR.041207","article-title":"Bone resorption and osteoporotic fractures in elderly men: the dubbo osteoporosis epidemiology study","volume":"20","author":"Meier","year":"2005","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2015.08.014_bb0135","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s00198-010-1501-1","article-title":"Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: a need for international reference standards","volume":"22","author":"Vasikaran","year":"2011","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2015.08.014_bb0140","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.bone.2014.05.016","article-title":"New developments in biological markers of bone metabolism in osteoporosis","volume":"66","author":"Garnero","year":"2014","journal-title":"Bone"},{"key":"10.1016\/j.bone.2015.08.014_bb0145","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.bbrc.2006.02.016","article-title":"Periostin is an extracellular matrix protein required for eruption of incisors in mice","volume":"342","author":"Kii","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bone.2015.08.014_bb0150","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.jaci.2006.02.046","article-title":"Periostin: a novel component of subepithelial fibrosis of bronchial asthma downstream of IL-4 and IL-13 signals","volume":"118","author":"Takayama","year":"2006","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.bone.2015.08.014_bb0155","doi-asserted-by":"crossref","first-page":"13294","DOI":"10.1074\/jbc.M109.088864","article-title":"Interaction between periostin and BMP-1 promotes proteolytic activation of lysyl oxidase","volume":"285","author":"Maruhashi","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bone.2015.08.014_bb0160","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0058726","article-title":"Zoledronate effects on systemic and jaw osteopenias in ovariectomized periostin-deficient mice","volume":"8","author":"Bonnet","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.bone.2015.08.014_bb0165","doi-asserted-by":"crossref","first-page":"2028","DOI":"10.1074\/jbc.M109.051961","article-title":"Incorporation of tenascin-C into the extracellular matrix by periostin underlies an extracellular meshwork architecture","volume":"285","author":"Kii","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bone.2015.08.014_bb0170","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.matbio.2014.04.007","article-title":"Periostin, a multifunctional matricellular protein in inflammatory and tumor microenvironments","volume":"37","author":"Liu","year":"2014","journal-title":"Matrix Biol."},{"key":"10.1016\/j.bone.2015.08.014_bb0175","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1186\/1476-4598-6-80","article-title":"Human periostin gene expression in normal tissues, tumors and melanoma: evidences for periostin production by both stromal and melanoma cells","volume":"6","author":"Tilman","year":"2007","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.bone.2015.08.014_bb0180","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1002\/ijc.25591","article-title":"Increased expression and serum levels of the stromal cell-secreted protein periostin in breast cancer bone metastases","volume":"128","author":"Contie","year":"2011","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.bone.2015.08.014_bb0185","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1002\/jcb.22214","article-title":"Role of hypoxia in the hallmarks of human cancer","volume":"107","author":"Ruan","year":"2009","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.bone.2015.08.014_bb0190","doi-asserted-by":"crossref","first-page":"3992","DOI":"10.1128\/MCB.24.9.3992-4003.2004","article-title":"Acquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expression","volume":"24","author":"Shao","year":"2004","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bone.2015.08.014_bb0195","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1023\/A:1021899904332","article-title":"Elevated serum periostin levels in patients with bone metastases from breast but not lung cancer","volume":"77","author":"Sasaki","year":"2003","journal-title":"Breast Cancer Res. Treat."}],"container-title":["Bone"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328215003257?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328215003257?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,7,18]],"date-time":"2018-07-18T20:50:33Z","timestamp":1531947033000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S8756328215003257"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":39,"alternative-id":["S8756328215003257"],"URL":"https:\/\/doi.org\/10.1016\/j.bone.2015.08.014","relation":{},"ISSN":["8756-3282"],"issn-type":[{"value":"8756-3282","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Plasma periostin associates significantly with non-vertebral but not vertebral fractures in postmenopausal women: Clinical evidence for the different effects of periostin depending on the skeletal site","name":"articletitle","label":"Article Title"},{"value":"Bone","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bone.2015.08.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}