{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T21:40:30Z","timestamp":1772314830622,"version":"3.50.1"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100006095","name":"South-Eastern Norway Regional Health Authority","doi-asserted-by":"publisher","award":["2014\/1403"],"award-info":[{"award-number":["2014\/1403"]}],"id":[{"id":"10.13039\/501100006095","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Oslo University Hospital"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bone"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.bone.2019.07.014","type":"journal-article","created":{"date-parts":[[2019,7,16]],"date-time":"2019-07-16T11:36:01Z","timestamp":1563276961000},"page":"436-445","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":44,"special_numbering":"C","title":["Bone metabolism, bone mineral density and low-energy fractures 10\u202fyears after Roux-en-Y gastric bypass"],"prefix":"10.1016","volume":"127","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2213-6545","authenticated-orcid":false,"given":"Ingvild Kristine","family":"Blom-H\u00f8gest\u00f8l","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Hewitt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica","family":"Chahal-Kummen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cathrine","family":"Brunborg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanne L\u00f8vdal","family":"Gulseth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jon A.","family":"Kristinsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik Fink","family":"Eriksen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom","family":"Mala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.bone.2019.07.014_bb0005","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.1007\/s11695-017-2666-x","article-title":"Bariatric surgery and endoluminal procedures: IFSO worldwide survey 2014","volume":"27","author":"Angrisani","year":"2017","journal-title":"Obes. Surg."},{"issue":"14","key":"10.1016\/j.bone.2019.07.014_bb0010","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1001\/jama.292.14.1724","article-title":"Bariatric surgery: a systematic review and meta-analysis","volume":"292","author":"Buchwald","year":"2004","journal-title":"Jama"},{"issue":"12","key":"10.1016\/j.bone.2019.07.014_bb0015","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1056\/NEJMoa1700459","article-title":"Weight and metabolic outcomes 12 years after gastric bypass","volume":"377","author":"Adams","year":"2017","journal-title":"N. Engl. J. Med."},{"issue":"8","key":"10.1016\/j.bone.2019.07.014_bb0020","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1056\/NEJMoa066603","article-title":"Long-term mortality after gastric bypass surgery","volume":"357","author":"Adams","year":"2007","journal-title":"N. Engl. J. Med."},{"issue":"1","key":"10.1016\/j.bone.2019.07.014_bb0025","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s11695-015-1724-5","article-title":"Changes in bone metabolism in morbidly obese patients after bariatric surgery: a meta-analysis","volume":"26","author":"Liu","year":"2016","journal-title":"Obes. Surg."},{"issue":"4","key":"10.1016\/j.bone.2019.07.014_bb0030","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1210\/jc.2014-4341","article-title":"Two-year changes in bone density after roux-en-Y gastric bypass surgery","volume":"100","author":"Yu","year":"2015","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"8","key":"10.1016\/j.bone.2019.07.014_bb0035","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1002\/jbmr.2467","article-title":"Intestinal calcium absorption decreases dramatically after gastric bypass surgery despite optimization of vitamin D status","volume":"30","author":"Schafer","year":"2015","journal-title":"J. Bone Min. Res."},{"key":"10.1016\/j.bone.2019.07.014_bb0040","series-title":"Changes in Bone Quality after Roux-En-Y Gastric Bypass: A Prospective Cohort Study in Subjects with and without Type 2 Diabetes","author":"Blom-H\u00f8gest\u00f8l","year":"2019"},{"issue":"11","key":"10.1016\/j.bone.2019.07.014_bb0045","doi-asserted-by":"crossref","first-page":"4104","DOI":"10.1210\/jc.2018-01496","article-title":"Longitudinal 5-year evaluation of bone density and microarchitecture after roux-en-Y gastric bypass surgery","volume":"103","author":"Lindeman","year":"2018","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"6","key":"10.1016\/j.bone.2019.07.014_bb0050","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1002\/jbmr.3101","article-title":"Fracture risk after bariatric surgery: roux-en-Y gastric bypass versus adjustable gastric banding","volume":"32","author":"Yu","year":"2017","journal-title":"J. Bone Min. Res."},{"issue":"12","key":"10.1016\/j.bone.2019.07.014_bb0055","doi-asserted-by":"crossref","first-page":"2122","DOI":"10.1002\/jbmr.3553","article-title":"Fracture risk after gastric bypass surgery: a retrospective cohort study","volume":"33","author":"Axelsson","year":"2018","journal-title":"J. Bone Min. Res."},{"issue":"3","key":"10.1016\/j.bone.2019.07.014_bb0060","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1111\/cen.13531","article-title":"Relationships of serum 25-hydroxyvitamin D, ionized calcium and parathyroid hormone after obesity surgery","volume":"88","author":"Hewitt","year":"2018","journal-title":"Clin. Endocrinol."},{"issue":"4","key":"10.1016\/j.bone.2019.07.014_bb0065","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1007\/s11695-007-9393-7","article-title":"Calcium intake and metabolic bone disease after eight years of Roux-en-Y gastric bypass","volume":"18","author":"Duran de Campos","year":"2008","journal-title":"Obes. Surg."},{"issue":"4","key":"10.1016\/j.bone.2019.07.014_bb0070","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1381\/096089292765559936","article-title":"Biochemical evidence of metabolic bone disease in women following roux-Y gastric bypass for morbid obesity","volume":"2","author":"Ott","year":"1992","journal-title":"Obes. Surg."},{"issue":"1","key":"10.1016\/j.bone.2019.07.014_bb0075","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.soard.2013.05.003","article-title":"Five-year outcome after gastric bypass for morbid obesity in a Norwegian cohort","volume":"10","author":"Aftab","year":"2014","journal-title":"Surg. Obes. Relat. Dis."},{"issue":"4","key":"10.1016\/j.bone.2019.07.014_bb0080","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1089\/109264203322333557","article-title":"Laparoscopic gastric bypass surgery: current technique","volume":"13","author":"Schauer","year":"2003","journal-title":"J. Laparoendosc. Adv. Surg. Tech. A"},{"issue":"4","key":"10.1016\/j.bone.2019.07.014_bb0085","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.jocd.2010.06.002","article-title":"In vivo precision of the GE Lunar iDXA densitometer for the measurement of total-body, lumbar spine, and femoral bone mineral density in adults","volume":"13","author":"Hind","year":"2010","journal-title":"J. Clin. Densitom."},{"issue":"1","key":"10.1016\/j.bone.2019.07.014_bb0090","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.jocd.2013.06.001","article-title":"In vivo precision of the GE lunar iDXA for the assessment of lumbar spine, total hip, femoral neck, and total body bone mineral density in severely obese patients","volume":"17","author":"Carver","year":"2014","journal-title":"J. Clin. Densitom."},{"issue":"12","key":"10.1016\/j.bone.2019.07.014_bb0095","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1515\/JPEM.2006.19.12.1413","article-title":"Serum osteocalcin and parathyroid hormone in healthy children assessed with two new automated assays","volume":"19","author":"Vietri","year":"2006","journal-title":"J. Pediatr. Endocrinol. Metab."},{"key":"10.1016\/j.bone.2019.07.014_bb0100","series-title":"Official Positions of the International Society for Clinical Densitometry","author":"ISCD","year":"2015"},{"key":"10.1016\/j.bone.2019.07.014_bb0105","series-title":"Assessment of Fracture Risk and its Application to Screening for Postmenopausal Osteoporosis. Report of a WHO Study Group, World Health Organization Technical Report Series","first-page":"1","volume":"vol. 843","year":"1994"},{"issue":"4","key":"10.1016\/j.bone.2019.07.014_bb0110","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/s001980050224","article-title":"Interim report and recommendations of the World Health Organization task-force for osteoporosis","volume":"10","author":"Genant","year":"1999","journal-title":"Osteoporos. Int."},{"issue":"7","key":"10.1016\/j.bone.2019.07.014_bb0115","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1210\/jc.2011-0385","article-title":"Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline","volume":"96","author":"Holick","year":"2011","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"2","key":"10.1016\/j.bone.2019.07.014_bb0120","doi-asserted-by":"crossref","first-page":"337","DOI":"10.4158\/EP12437.GL","volume":"19","author":"Mechanick","year":"2013","journal-title":"Endocr. Pract."},{"issue":"4","key":"10.1016\/j.bone.2019.07.014_bb0125","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1210\/jc.2011-3362","article-title":"Executive summary of the stages of reproductive aging workshop + 10: addressing the unfinished agenda of staging reproductive aging","volume":"97","author":"Harlow","year":"2012","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"2","key":"10.1016\/j.bone.2019.07.014_bb0130","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1037\/0033-2909.86.2.420","article-title":"Intraclass correlations: uses in assessing rater reliability","volume":"86","author":"Shrout","year":"1979","journal-title":"Psychol. Bull."},{"issue":"6","key":"10.1016\/j.bone.2019.07.014_bb0135","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s10654-009-9333-z","article-title":"Bone mineral density at the hip in Norwegian women and men--prevalence of osteoporosis depends on chosen references: the Tromso study","volume":"24","author":"Emaus","year":"2009","journal-title":"Eur. J. Epidemiol."},{"key":"10.1016\/j.bone.2019.07.014_bb0140","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.bone.2016.11.014","article-title":"Effects of Roux-en-Y gastric bypass and sleeve gastrectomy on bone mineral density and marrow adipose tissue","volume":"95","author":"Bredella","year":"2017","journal-title":"Bone"},{"issue":"6","key":"10.1016\/j.bone.2019.07.014_bb0145","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1002\/jbmr.3371","article-title":"Effects of gastric bypass surgery on bone mass and microarchitecture occur early and particularly impact postmenopausal women","volume":"33","author":"Schafer","year":"2018","journal-title":"J. Bone Miner. Res. Off. J. Am. Soc. Bone Miner. Res."},{"issue":"6","key":"10.1016\/j.bone.2019.07.014_bb0150","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1007\/s00198-009-0838-9","article-title":"Bone turnover markers: understanding their value in clinical trials and clinical practice","volume":"20","author":"Civitelli","year":"2009","journal-title":"Osteoporos. Int."},{"issue":"11","key":"10.1016\/j.bone.2019.07.014_bb0155","doi-asserted-by":"crossref","first-page":"1940","DOI":"10.1038\/oby.2006.226","article-title":"True fractional calcium absorption is decreased after Roux-en-Y gastric bypass surgery","volume":"14","author":"Riedt","year":"2006","journal-title":"Obesity (Silver Spring, Md.)"},{"issue":"19","key":"10.1016\/j.bone.2019.07.014_bb0160","first-page":"1887","article-title":"Follow-up after bariatric surgery","volume":"131","author":"Hofso","year":"2011","journal-title":"Tidsskr. Nor. Laegeforen."},{"issue":"6","key":"10.1016\/j.bone.2019.07.014_bb0165","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1159\/000481825","article-title":"Practical recommendations of the obesity management task force of the European Association for the Study of obesity for the post-bariatric surgery medical management","volume":"10","author":"Busetto","year":"2017","journal-title":"Obes. Facts"},{"issue":"5","key":"10.1016\/j.bone.2019.07.014_bb0170","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1007\/s11695-019-03711-z","article-title":"Patient perspectives on adherence with micronutrient supplementation after bariatric surgery","volume":"29","author":"Mahawar","year":"2019","journal-title":"Obes. Surg."},{"issue":"3","key":"10.1016\/j.bone.2019.07.014_bb0175","doi-asserted-by":"crossref","first-page":"E190","DOI":"10.1002\/oby.20031","article-title":"Adherence to vitamin supplementation following adolescent bariatric surgery","volume":"21","author":"Modi","year":"2013","journal-title":"Obesity (Silver Spring, Md.)"},{"issue":"2","key":"10.1016\/j.bone.2019.07.014_bb0180","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1210\/er.2015-1106","article-title":"Role of thyroid hormones in skeletal development and bone maintenance","volume":"37","author":"Bassett","year":"2016","journal-title":"Endocr. Rev."},{"issue":"2","key":"10.1016\/j.bone.2019.07.014_bb0185","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/8756-3282(86)90681-2","article-title":"Kinetics of trabecular bone resorption and formation in hypothyroidism: evidence for a positive balance per remodeling cycle","volume":"7","author":"Eriksen","year":"1986","journal-title":"Bone"},{"key":"10.1016\/j.bone.2019.07.014_bb0190","doi-asserted-by":"crossref","first-page":"796871","DOI":"10.1155\/2015\/796871","article-title":"Bone indices in thyroidectomized patients on long-term substitution therapy with levothyroxine assessed by DXA and HR-pQCT","volume":"2015","author":"Moser","year":"2015","journal-title":"J. Thyroid. Res."},{"issue":"20","key":"10.1016\/j.bone.2019.07.014_bb0195","doi-asserted-by":"crossref","first-page":"2688","DOI":"10.1001\/jama.1991.03460200068037","article-title":"Bone mineral density in premenopausal women receiving long-term physiological doses of levothyroxine","volume":"265","author":"Kung","year":"1991","journal-title":"Jama"},{"issue":"21","key":"10.1016\/j.bone.2019.07.014_bb0200","doi-asserted-by":"crossref","first-page":"3137","DOI":"10.1001\/jama.1988.03720210027023","article-title":"Long-term L-thyroxine therapy is associated with decreased hip bone density in premenopausal women","volume":"259","author":"Paul","year":"1988","journal-title":"Jama"},{"issue":"5","key":"10.1016\/j.bone.2019.07.014_bb0205","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1002\/jbmr.5650080507","article-title":"Effects of weight and body mass index on bone mineral density in men and women: the Framingham study","volume":"8","author":"Felson","year":"1993","journal-title":"J. Bone Miner. Res. Off. J. Am. Soc. Bone Miner. Res."},{"issue":"2","key":"10.1016\/j.bone.2019.07.014_bb0210","first-page":"128","article-title":"Biological underpinnings of Frost's mechanostat thresholds: the important role of osteocytes","volume":"10","author":"Hughes","year":"2010","journal-title":"J. Musculoskelet. Neuronal Interact."},{"issue":"1","key":"10.1016\/j.bone.2019.07.014_bb0215","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/jbmr.2017","article-title":"A meta-analysis of the association of fracture risk and body mass index in women","volume":"29","author":"Johansson","year":"2014","journal-title":"J. Bone Miner. Res."},{"issue":"6","key":"10.1016\/j.bone.2019.07.014_bb0220","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/j.soard.2009.05.014","article-title":"Obesity in orthopedic patients","volume":"5","author":"Bergkvist","year":"2009","journal-title":"Surg. Obes. Relat. Dis."},{"issue":"1","key":"10.1016\/j.bone.2019.07.014_bb0225","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s00198-017-4223-9","article-title":"Effects of obesity and diabetes on rate of bone density loss, osteoporosis international: a journal established as result of cooperation between the European Foundation for Osteoporosis and the","volume":"29","author":"Leslie","year":"2018","journal-title":"National Osteoporosis Foundation of the USA"},{"key":"10.1016\/j.bone.2019.07.014_bb0230","doi-asserted-by":"crossref","first-page":"i3794","DOI":"10.1136\/bmj.i3794","article-title":"Change in fracture risk and fracture pattern after bariatric surgery: nested case-control study","volume":"354","author":"Rousseau","year":"2016","journal-title":"BMJ"},{"issue":"3","key":"10.1016\/j.bone.2019.07.014_bb0235","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1002\/art.21984","article-title":"Population-based assessment of adverse events associated with long-term glucocorticoid use","volume":"55","author":"Curtis","year":"2006","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.bone.2019.07.014_bb0240","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1471-2474-13-3","article-title":"Prevalence of vertebral fractures in women and men in the population-based Tromso study","volume":"13","author":"Waterloo","year":"2012","journal-title":"BMC Musculoskelet. Disord."},{"issue":"3","key":"10.1016\/j.bone.2019.07.014_bb0245","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1359\/jbmr.081103","article-title":"Vertebral fracture status and the World Health Organization risk factors for predicting osteoporotic fracture risk","volume":"24","author":"Chen","year":"2009","journal-title":"J. Bone Miner. Res."}],"container-title":["Bone"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328219302881?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328219302881?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T17:49:21Z","timestamp":1757612961000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S8756328219302881"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":49,"alternative-id":["S8756328219302881"],"URL":"https:\/\/doi.org\/10.1016\/j.bone.2019.07.014","relation":{},"ISSN":["8756-3282"],"issn-type":[{"value":"8756-3282","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bone metabolism, bone mineral density and low-energy fractures 10\u202fyears after Roux-en-Y gastric bypass","name":"articletitle","label":"Article Title"},{"value":"Bone","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bone.2019.07.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}