{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T11:47:35Z","timestamp":1788608855893,"version":"build-2803163510"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["H28-Seisaku-Shitei-009"],"award-info":[{"award-number":["H28-Seisaku-Shitei-009"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["H29-Seisaku-Shitei-009"],"award-info":[{"award-number":["H29-Seisaku-Shitei-009"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bone"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1016\/j.bone.2019.115122","type":"journal-article","created":{"date-parts":[[2019,11,3]],"date-time":"2019-11-03T11:46:10Z","timestamp":1572781570000},"page":"115122","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Nationwide in-hospital mortality following major fractures among hemodialysis patients and the general population: An observational cohort study"],"prefix":"10.1016","volume":"130","author":[{"given":"Shintaro","family":"Mandai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidehiko","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soichiro","family":"Iimori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shotaro","family":"Naito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruna","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumiaki","family":"Ando","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichiro","family":"Susa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyoshi","family":"Isobe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takayasu","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naohiro","family":"Nomura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eisei","family":"Sohara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomokazu","family":"Okado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Uchida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyohide","family":"Fushimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatemitsu","family":"Rai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bone.2019.115122_bib0005","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1172\/JCI110039","article-title":"Differential changes in bone mineral density of the appendicular and axial skeleton with aging: relationship to spinal osteoporosis","volume":"67","author":"Riggs","year":"1981","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bone.2019.115122_bib0010","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1046\/j.1523-1755.1999.00617.x","article-title":"Bone mineral density and biochemical markers of bone turnover in patients with predialysis chronic renal failure","volume":"56","author":"Rix","year":"1999","journal-title":"Kidney Int."},{"key":"10.1016\/j.bone.2019.115122_bib0015","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1007\/s00198-006-0172-4","article-title":"An estimate of the worldwide prevalence and disability associated with osteoporotic fractures","volume":"17","author":"Johnell","year":"2006","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2019.115122_bib0020","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1359\/jbmr.2003.18.6.1139","article-title":"Adverse outcomes of osteoporotic fractures in the general population","volume":"18","author":"Melton","year":"2003","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2019.115122_bib0025","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1046\/j.1532-5415.2003.51110.x","article-title":"Estimating hip fracture morbidity, mortality and costs","volume":"51","author":"Braithwaite","year":"2003","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.bone.2019.115122_bib0030","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1093\/ageing\/afp221","article-title":"Excess mortality in men compared with women following a hip fracture. National analysis of comedications, comorbidity and survival","volume":"39","author":"Kannegaard","year":"2010","journal-title":"Age Ageing"},{"key":"10.1016\/j.bone.2019.115122_bib0035","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1186\/1471-2474-12-105","article-title":"Mortality and cause of death in hip fracture patients aged 65 or older: a population-based study","volume":"12","author":"Panula","year":"2011","journal-title":"BMC Musculoskelet Disord."},{"key":"10.1016\/j.bone.2019.115122_bib0040","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/S8756-3282(03)00061-9","article-title":"The components of excess mortality after hip fracture","volume":"32","author":"Kanis","year":"2003","journal-title":"Bone"},{"key":"10.1016\/j.bone.2019.115122_bib0045","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/S0140-6736(98)09075-8","article-title":"Mortality after all major types of osteoporotic fracture in men and women: an observational study","volume":"353","author":"Center","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.bone.2019.115122_bib0050","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1007\/s00198-003-1490-4","article-title":"Mortality after osteoporotic fractures","volume":"15","author":"Johnell","year":"2004","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2019.115122_bib0055","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1056\/NEJMoa041031","article-title":"Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization","volume":"351","author":"Go","year":"2004","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.bone.2019.115122_bib0060","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1111\/j.1523-1755.2000.00337.x","article-title":"Mortality caused by sepsis in patients with end-stage renal disease compared with the general population","volume":"58","author":"Sarnak","year":"2000","journal-title":"Kidney Int."},{"key":"10.1016\/j.bone.2019.115122_bib0065","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1053\/j.ajkd.2013.02.368","article-title":"Trends in hip fracture rates in US hemodialysis patients, 1993-2010","volume":"62","author":"Arneson","year":"2013","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.bone.2019.115122_bib0070","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1053\/j.ajkd.2013.07.002","article-title":"Hip fractures in hemodialysis patients","volume":"62","author":"Delgado","year":"2013","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.bone.2019.115122_bib0075","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1053\/j.ajkd.2005.09.024","article-title":"PTH and the risks for hip, vertebral, and pelvic fractures among patients on dialysis","volume":"47","author":"Danese","year":"2006","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.bone.2019.115122_bib0080","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1681\/ASN.2007010022","article-title":"Fracture risk after parathyroidectomy among chronic hemodialysis patients","volume":"18","author":"Rudser","year":"2007","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.bone.2019.115122_bib0085","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1093\/ndt\/gfr317","article-title":"Diagnostic usefulness of bone mineral density and biochemical markers of bone turnover in predicting fracture in CKD stage 5D patients--a single-center cohort study","volume":"27","author":"Iimori","year":"2012","journal-title":"Nephrol. Dial. Transplant."},{"key":"10.1016\/j.bone.2019.115122_bib0090","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1038\/ki.2013.279","article-title":"High rates of death and hospitalization follow bone fracture among hemodialysis patients","volume":"85","author":"Tentori","year":"2014","journal-title":"Kidney Int."},{"key":"10.1016\/j.bone.2019.115122_bib0095","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2012-002412","article-title":"Incidence and risk factors for mortality of vertebral osteomyelitis: a retrospective analysis using the Japanese diagnosis procedure combination database","volume":"3","author":"Akiyama","year":"2013","journal-title":"BMJ Open"},{"key":"10.1016\/j.bone.2019.115122_bib0100","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.ekir.2017.10.015","article-title":"Dialysis case volume associated with in-hospital mortality in maintenance Dialysis patients","volume":"3","author":"Mandai","year":"2017","journal-title":"Kidney Int. Rep."},{"key":"10.1016\/j.bone.2019.115122_bib0105","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1001\/jama.2009.50","article-title":"Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women","volume":"301","author":"Bliuc","year":"2009","journal-title":"JAMA"},{"key":"10.1016\/j.bone.2019.115122_bib0110","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0143800","article-title":"The epidemiology of hip and major osteoporotic fractures in a Dutch population of community-dwelling elderly: implications for the Dutch FRAX\u00ae algorithm","volume":"10","author":"Klop","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.bone.2019.115122_bib0115","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1093\/aje\/kwq433","article-title":"Updating and validating the Charlson comorbidity index and score for risk adjustment in hospital discharge abstracts using data from 6 countries","volume":"173","author":"Quan","year":"2011","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.bone.2019.115122_bib0120","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1177\/1536867X1201200209","article-title":"Using the margins command to estimate and interpret adjusted predictions and marginal effects","volume":"12","author":"Williams","year":"2012","journal-title":"Stata J."},{"key":"10.1016\/j.bone.2019.115122_bib0125","article-title":"Association between body mass index and all-cause death in Japanese population: pooled individual participant data analysis of 13 cohort studies","author":"Hozawa","year":"2018","journal-title":"J. Epidemiol."},{"key":"10.1016\/j.bone.2019.115122_bib0130","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2017-018836","article-title":"Incidence and mortality of fractures by frailty level over 80 years of age: cohort study using UK electronic health records","volume":"8","author":"Ravindrarajah","year":"2018","journal-title":"BMJ Open"},{"key":"10.1016\/j.bone.2019.115122_bib0135","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1111\/1744-9987.12378","article-title":"An overview of regular Dialysis treatment in Japan (As of 31 December 2013)","volume":"19","author":"Masakane","year":"2015","journal-title":"Ther. Apher. Dial."},{"key":"10.1016\/j.bone.2019.115122_bib0140","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1111\/j.1744-9987.2012.01144.x","article-title":"Cause-specific excess mortality among dialysis patients: comparison with the general population in Japan","volume":"17","author":"Wakasugi","year":"2013","journal-title":"Ther. Apher. Dial."},{"key":"10.1016\/j.bone.2019.115122_bib0145","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1111\/nep.12830","article-title":"Impact of end-stage renal disease on hospital outcomes among patients admitted to intensive care units: a retrospective matched-pair cohort study","volume":"22","author":"Iwagami","year":"2017","journal-title":"Nephrology (Carlton)"},{"key":"10.1016\/j.bone.2019.115122_bib0150","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1111\/nep.13242","article-title":"Association of dialysis with in-hospital disability progression and mortality in community-onset stroke","volume":"24","author":"Usui","year":"2019","journal-title":"Nephrology (Carlton)"},{"key":"10.1016\/j.bone.2019.115122_bib0155","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1097\/01.bot.0000155311.04886.7e","article-title":"Mortality after low-energy fractures in patients aged at least 45 years old","volume":"19","author":"Shortt","year":"2005","journal-title":"J. Orthop. Trauma"},{"key":"10.1016\/j.bone.2019.115122_bib0160","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1302\/0301-620X.96B7.32894","article-title":"The outcome of proximal humeral fractures in the elderly: predictors of mortality and function","volume":"96-B","author":"Clement","year":"2014","journal-title":"Bone Joint J."},{"issue":"Suppl. 1","key":"10.1016\/j.bone.2019.115122_bib0165","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/1744-9987.12296","volume":"19","author":"Kukita","year":"2015","journal-title":"Ther. Apher. Dial."},{"key":"10.1016\/j.bone.2019.115122_bib0170","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.je.2016.09.009","article-title":"Validity of diagnoses, procedures, and laboratory data in Japanese administrative data","volume":"27","author":"Yamana","year":"2017","journal-title":"J. Epidemiol."},{"key":"10.1016\/j.bone.2019.115122_bib0175","doi-asserted-by":"crossref","first-page":"955","DOI":"10.2215\/CJN.12181116","article-title":"Examining the association between hemodialysis access type and mortality: the role of access complications","volume":"12","author":"Ravani","year":"2017","journal-title":"Clin. J. Am. Soc. Nephrol."}],"container-title":["Bone"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328219304156?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328219304156?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T03:39:39Z","timestamp":1762659579000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S8756328219304156"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":35,"alternative-id":["S8756328219304156"],"URL":"https:\/\/doi.org\/10.1016\/j.bone.2019.115122","relation":{},"ISSN":["8756-3282"],"issn-type":[{"value":"8756-3282","type":"print"}],"subject":[],"published":{"date-parts":[[2020,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nationwide in-hospital mortality following major fractures among hemodialysis patients and the general population: An observational cohort study","name":"articletitle","label":"Article Title"},{"value":"Bone","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bone.2019.115122","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"115122"}}