{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T21:27:53Z","timestamp":1793222873802,"version":"4.5.0"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,4,12]],"date-time":"2022-04-12T00:00:00Z","timestamp":1649721600000},"content-version":"am","delay-in-days":285,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100006754","name":"US Army Research Laboratory","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006754","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bone"],"published-print":{"date-parts":[[2021,7]]},"DOI":"10.1016\/j.bone.2021.115931","type":"journal-article","created":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T11:49:44Z","timestamp":1616500184000},"page":"115931","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Cortical and trabecular morphometric properties of the human calvarium"],"prefix":"10.1016","volume":"148","author":[{"given":"Kevin","family":"Adanty","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karyne N.","family":"Rabey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Doschak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kapil B.","family":"Bhagavathula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James D.","family":"Hogan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan L.","family":"Romanyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samer","family":"Adeeb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Ouellet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas A.","family":"Plaisted","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sikhanda S.","family":"Satapathy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher R.","family":"Dennison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bone.2021.115931_bb0005","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.jmbbm.2018.10.035","article-title":"Structural analysis of the frontal and parietal bones of the human skull","volume":"90","author":"Alexander","year":"2019","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.bone.2021.115931_bb0010","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.bone.2015.04.031","article-title":"Variation of bone layer thicknesses and trabecular volume fraction in the adult male human calvarium","volume":"77","author":"Boruah","year":"2015","journal-title":"Bone"},{"key":"10.1016\/j.bone.2021.115931_bb0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2019\/6515797","article-title":"An investigation on the correlation between the mechanical properties of human skull bone, its geometry, microarchitectural properties, and water content","volume":"2019","author":"Lee","year":"2019","journal-title":"J. Healthc. Eng."},{"key":"10.1016\/j.bone.2021.115931_bb0020","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1111\/joa.12259","article-title":"Estimation of skull table thickness with clinical CT and validation with microCT","volume":"226","author":"Lillie","year":"2015","journal-title":"J. Anat."},{"key":"10.1016\/j.bone.2021.115931_bb0025","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/0021-9290(70)90059-X","article-title":"Mechanical properties of cranial bone","volume":"3","author":"McElhaney","year":"1970","journal-title":"J. Biomech."},{"key":"10.1016\/j.bone.2021.115931_bb0030","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1016\/j.jbiomech.2009.05.030","article-title":"The mechanical properties of cranial bone: the effect of loading rate and cranial sampling position","volume":"42","author":"Motherway","year":"2009","journal-title":"J. Biomech."},{"key":"10.1016\/j.bone.2021.115931_bb0035","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/ar.10131","article-title":"Material properties of the inner and outer cortical tables of the human parietal bone","volume":"268","author":"Peterson","year":"2002","journal-title":"Anat. Rec."},{"key":"10.1016\/j.bone.2021.115931_bb0040","doi-asserted-by":"crossref","first-page":"103384","DOI":"10.1016\/j.jmbbm.2019.103384","article-title":"Skull fracture prediction through subject-specific finite element modelling is highly sensitive to model parameters","volume":"100","author":"De Kegel","year":"2019","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.bone.2021.115931_bb0045","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.jmbbm.2018.10.032","article-title":"The mechanical response of commercially available bone simulants for quasi-static and dynamic loading","volume":"90","author":"Brown","year":"2019","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.bone.2021.115931_bb0050","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.jmbbm.2017.02.023","article-title":"Investigation of the elastic modulus, tensile and flexural strength of five skull simulant materials for impact testing of a forensic skin\/skull\/brain model","volume":"68","author":"Falland-Cheung","year":"2017","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.bone.2021.115931_bb0055","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2013.00013","article-title":"Development of a human cranial bone surrogate for impact studies","volume":"1","author":"Roberts","year":"2013","journal-title":"Front. Bioeng. Biotechnol."},{"key":"10.1016\/j.bone.2021.115931_bb0060","first-page":"821","article-title":"On the ability of morphometric indices of skull Diplo\u00eb to explain variation in bone fracture force and fracture strain in four-point bending: a preliminary step toward a simulant fracture model","volume":"2020","author":"Adanty","year":"2020","journal-title":"IRCOBI Conf."},{"key":"10.1016\/j.bone.2021.115931_bb0065","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1016\/j.jbiomech.2013.10.060","article-title":"Geometrical and material parameters to assess the macroscopic mechanical behaviour of fresh cranial bone samples","volume":"47","author":"Auperrin","year":"2014","journal-title":"J. Biomech."},{"key":"10.1016\/j.bone.2021.115931_bb0070","series-title":"Response of Human Skull Bone to Dynamic Compressive Loading","first-page":"12","author":"Boruah","year":"2013"},{"key":"10.1016\/j.bone.2021.115931_bb0075","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.mehy.2018.05.006","article-title":"Fractal dimension: a complementary diagnostic indicator of osteoporosis to bone mineral density","volume":"116","author":"Chen","year":"2018","journal-title":"Med. Hypotheses"},{"key":"10.1016\/j.bone.2021.115931_bb0080","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2015.00080","article-title":"Using micro-CT derived bone microarchitecture to analyze bone stiffness \u2013 a case study on osteoporosis rat bone","volume":"6","author":"Wu","year":"2015","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.bone.2021.115931_bb0085","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1002\/jbmr.141","article-title":"Guidelines for assessment of bone microstructure in rodents using micro\u2013computed tomography","volume":"25","author":"Bouxsein","year":"2010","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2021.115931_bb0090","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/213234","article-title":"Age-related changes in trabecular and cortical bone microstructure","volume":"2013","author":"Chen","year":"2013","journal-title":"Int. J. Endocrinol."},{"key":"10.1016\/j.bone.2021.115931_bb0095","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1007\/s00774-004-0557-4","article-title":"Regional variations in microstructural properties of vertebral trabeculae with aging","volume":"23","author":"Gong","year":"2005","journal-title":"J. Bone Miner. Metab."},{"key":"10.1016\/j.bone.2021.115931_bb0100","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.bonr.2015.10.001","article-title":"The micro-architecture of human cancellous bone from fracture neck of femur patients in relation to the structural integrity and fracture toughness of the tissue","volume":"3","author":"Greenwood","year":"2015","journal-title":"Bone Rep."},{"key":"10.1016\/j.bone.2021.115931_bb0105","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1016\/S0140-6736(10)60320-0","article-title":"Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study","volume":"375","author":"Zebaze","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.bone.2021.115931_bb0110","series-title":"Department of Health and Human Servies: Visible Human Database","author":"U.S National Library of Medicine","year":"2000"},{"key":"10.1016\/j.bone.2021.115931_bb0115","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1002\/ajpa.1330080113","article-title":"A study of the differences between male and female skulls","volume":"8","author":"Keen","year":"1950","journal-title":"Am. J. Phys. Anthropol."},{"key":"10.1016\/j.bone.2021.115931_bb0120","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1359\/JBMR.041005","article-title":"Males have larger skeletal size and bone mass than females, despite comparable body size","volume":"20","author":"Nieves","year":"2005","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2021.115931_bb0125","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1046\/j.1365-2818.1997.1340694.x","article-title":"A new method for the model-independent assessment of thickness in three-dimensional images","volume":"185","author":"Hildebrand","year":"1997","journal-title":"J. Microsc."},{"key":"10.1016\/j.bone.2021.115931_bb0130","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1002\/jbmr.5650020617","article-title":"Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee","volume":"2","author":"Parfitt","year":"1987","journal-title":"J. Bone Miner. Res. Off. J. Am. Soc. Bone Miner. Res."},{"key":"10.1016\/j.bone.2021.115931_bb0135","series-title":"Morphometric Parameters in CT_ANALYSER 36","author":"Salmon","year":"2009"},{"key":"10.1016\/j.bone.2021.115931_bb0140","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1111\/joa.12446","article-title":"A review of trabecular bone functional adaptation: what have we learned from trabecular analyses in extant hominoids and what can we apply to fossils?","volume":"228","author":"Kivell","year":"2016","journal-title":"J. Anat."},{"key":"10.1016\/j.bone.2021.115931_bb0145","series-title":"Micro-Computed Tomography (Micro-CT) in Medicine and Engineering","first-page":"49","article-title":"Application of bone morphometry and densitometry by X-ray micro-CT to bone disease models and phenotypes","author":"Salmon","year":"2020"},{"key":"10.1016\/j.bone.2021.115931_bb0150","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/8756-3282(92)90078-B","article-title":"Trabecular bone pattern factor\u2014a new parameter for simple quantification of bone microarchitecture","volume":"13","author":"Hahn","year":"1992","journal-title":"Bone"},{"key":"10.1016\/j.bone.2021.115931_bb0155","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1145\/37402.37422","article-title":"Marching cubes: a high resolution 3D surface construction algorithm","volume":"21","author":"Lorensen","year":"1987","journal-title":"ACM SIGGRAPH Comput. Graph."},{"key":"10.1016\/j.bone.2021.115931_bb0160","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2015.00162","article-title":"Structure model index does not measure rods and plates in trabecular bone","volume":"6","author":"Salmon","year":"2015","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.bone.2021.115931_bb0165","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1002\/path.970","article-title":"Fractal dimension of trabecular bone: comparison of three histomorphometric computed techniques for measuring the architectural two-dimensional complexity","volume":"195","author":"Chappard","year":"2001","journal-title":"J. Pathol."},{"issue":"2","key":"10.1016\/j.bone.2021.115931_bb0170","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1148\/radiol.2272012051","article-title":"Sample size estimation: how many individuals should be studied?1","volume":"227","author":"Eng","year":"2003","journal-title":"Radiology."},{"key":"10.1016\/j.bone.2021.115931_bb0175","doi-asserted-by":"crossref","first-page":"2659","DOI":"10.1016\/j.jbiomech.2013.07.047","article-title":"Measurement of structural anisotropy in femoral trabecular bone using clinical-resolution CT images","volume":"46","author":"Kersh","year":"2013","journal-title":"J. Biomech."},{"key":"10.1016\/j.bone.2021.115931_bb0180","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1111\/cid.12109","article-title":"Micro-computed tomography assessment of human alveolar bone: bone density and three-dimensional micro-architecture","volume":"17","author":"Kim","year":"2015","journal-title":"Clin. Implant. Dent. Relat. Res."},{"key":"10.1016\/j.bone.2021.115931_bb0185","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1016\/j.jmbbm.2011.07.010","article-title":"Principal stiffness orientation and degree of anisotropy of human osteons based on nanoindentation in three distinct planes","volume":"4","author":"Reisinger","year":"2011","journal-title":"J. Mech. Behav. Biomed. Mater., Special Issue Soft Tissues"},{"key":"10.1016\/j.bone.2021.115931_bb0190","first-page":"411","article-title":"Quantification of bone quality using different cone beam computed tomography devices: accuracy assessment for edentulous human mandibles","volume":"9","author":"Van Dessel","year":"2016","journal-title":"Eur. J. Oral Implantol."},{"key":"10.1016\/j.bone.2021.115931_bb0195","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1359\/JBMR.040819","article-title":"Additive protective effects of estrogen and androgen treatment on trabecular bone in ovariectomized rats","volume":"19","author":"Tivesten","year":"2004","journal-title":"J. Bone Miner. Res. Off. J. Am. Soc. Bone Miner. Res."},{"key":"10.1016\/j.bone.2021.115931_bb0200","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1002\/ca.1076","article-title":"Fractal analysis of lumbar vertebral cancellous bone architecture","volume":"14","author":"Feltrin","year":"2001","journal-title":"Clin. Anat."},{"key":"10.1016\/j.bone.2021.115931_bb0205","series-title":"Using Cereal Science and Technology for the Benefit of Consumers","first-page":"395","article-title":"A comparison of visual assessment and digital fractal texture analysis of bread-crumb features","author":"Gonzales-Barron","year":"2005"},{"key":"10.1016\/j.bone.2021.115931_bb0210","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1359\/jbmr.2000.15.4.691","article-title":"Fractal dimension of trabecular bone projection texture is related to three-dimensional microarchitecture","volume":"15","author":"Pothuaud","year":"2000","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2021.115931_bb0215","first-page":"110","article-title":"The fractal dimension correlated to the bone mineral density","volume":"4","author":"Harrar","year":"2008","journal-title":"WSEAS Trans. Signal Process."},{"key":"10.1016\/j.bone.2021.115931_bb0220","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1533\/ijcr.2003.0243","article-title":"The creation of three-dimensional finite element models for simulating head impact biomechanics","volume":"8","author":"Horgan","year":"2003","journal-title":"Int. J. Crashworthiness"},{"key":"10.1016\/j.bone.2021.115931_bb0225","first-page":"123","article-title":"Correlation of an FE model of the human head with local brain motion--consequences for injury prediction","volume":"46","author":"Kleiven","year":"2002","journal-title":"Stapp Car Crash J."},{"key":"10.1016\/j.bone.2021.115931_bb0230","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.jmbbm.2013.08.022","article-title":"Development and validation of an advanced anisotropic visco-hyperelastic human brain FE model","volume":"33","author":"Sahoo","year":"2014","journal-title":"J. Mech. Behav. Biomed. Mater., Forensic Biomechanics"},{"key":"10.1016\/j.bone.2021.115931_bb0235","first-page":"1","article-title":"Investigation of traumatic brain injuries using the next generation of simulated injury monitor (SIMon) finite element head model","volume":"52","author":"Takhounts","year":"2008","journal-title":"Stapp Car Crash J."},{"key":"10.1016\/j.bone.2021.115931_bb0240","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0021-9290(71)90031-5","article-title":"Flexure of layered cranial bone","volume":"4","author":"Hubbard","year":"1971","journal-title":"J. Biomech."},{"key":"10.1016\/j.bone.2021.115931_bb0245","article-title":"The effects of embalming using a 4% formalin solution on the compressive mechanical properties of human cortical bone","author":"Ohman","year":"2008","journal-title":"Clin. Biomech."},{"key":"10.1016\/j.bone.2021.115931_bb0250","doi-asserted-by":"crossref","first-page":"543","DOI":"10.3109\/17453674.2012.727079","article-title":"Embalmed and fresh frozen human bones in orthopedic cadaveric studies: which bone is authentic and feasible?","volume":"83","author":"Topp","year":"2012","journal-title":"Acta Orthop."},{"key":"10.1016\/j.bone.2021.115931_bb0255","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s00223-008-9158-x","article-title":"Quantitative assessment of bone tissue mineralization with polychromatic micro-computed tomography","volume":"83","author":"Burghardt","year":"2008","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.bone.2021.115931_bb0260","doi-asserted-by":"crossref","first-page":"5138","DOI":"10.1118\/1.3480507","article-title":"Improved accuracy of cortical bone mineralization measured by polychromatic microcomputed tomography using a novel high mineral density composite calibration phantom","volume":"37","author":"Deuerling","year":"2010","journal-title":"Med. Phys."},{"key":"10.1016\/j.bone.2021.115931_bb0265","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1039\/b703220j","article-title":"Preparation and characterization of calibration standards for bone density determination by micro-computed tomography","volume":"132","author":"Schweizer","year":"2007","journal-title":"Analyst"},{"key":"10.1016\/j.bone.2021.115931_bb0270","doi-asserted-by":"crossref","first-page":"400","DOI":"10.4103\/0973-029X.102496","article-title":"Chemical and physical basics of routine formaldehyde fixation","volume":"16","author":"Thavarajah","year":"2012","journal-title":"J. Oral Maxillofac. Pathol. JOMFP"}],"container-title":["Bone"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328221000934?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328221000934?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T17:52:37Z","timestamp":1757613157000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S8756328221000934"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":54,"alternative-id":["S8756328221000934"],"URL":"https:\/\/doi.org\/10.1016\/j.bone.2021.115931","relation":{},"ISSN":["8756-3282"],"issn-type":[{"value":"8756-3282","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cortical and trabecular morphometric properties of the human calvarium","name":"articletitle","label":"Article Title"},{"value":"Bone","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bone.2021.115931","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown Copyright \u00a9 2021 Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"115931"}}