{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T02:50:30Z","timestamp":1787626230437,"version":"build-2736575974"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,12,7]],"date-time":"2021-12-07T00:00:00Z","timestamp":1638835200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011781","name":"Shriners Hospitals for Children","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011781","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bone"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.bone.2021.116282","type":"journal-article","created":{"date-parts":[[2021,12,8]],"date-time":"2021-12-08T12:20:18Z","timestamp":1638966018000},"page":"116282","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Fabric-elasticity relationships of tibial trabecular bone are similar in osteogenesis imperfecta and healthy individuals"],"prefix":"10.1016","volume":"155","author":[{"given":"Mathieu","family":"Simon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Indermaur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Schenk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyedmahdi","family":"Hosseinitabatabaei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bettina M.","family":"Willie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Zysset","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bone.2021.116282_bb0005","doi-asserted-by":"crossref","first-page":"2955","DOI":"10.1007\/s00198-016-3621-8","article-title":"In vivo assessment of bone structure and estimated bone strength by first- and second-generation HR-pQCT","volume":"27","author":"Agarwal","year":"2016","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2021.116282_bb0010","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1007\/s00198-019-04935-6","article-title":"Validation of distal radius failure load predictions by homogenized- and micro-finite element analyses based on second-generation high-resolution peripheral quantitative CT images","volume":"30","author":"Arias-Moreno","year":"2019","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2021.116282_bb0015","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1007\/s00198-021-05999-z","article-title":"The clinical application of high-resolution peripheral computed tomography (hr-pqct) in adults: state of the art and future directions","volume":"32","author":"Bergh","year":"2021","journal-title":"Osteoporosis Int."},{"key":"10.1016\/j.bone.2021.116282_bb0020","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1007\/s00198-017-4010-7","article-title":"The comparability of HR-pQCT bone measurements is improved by scanning anatomically standardized regions","volume":"28","author":"Bonaretti","year":"2017","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2021.116282_bb0025","doi-asserted-by":"crossref","first-page":"6508","DOI":"10.1210\/jc.2005-1258","article-title":"In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography","volume":"90","author":"Boutroy","year":"2005","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.bone.2021.116282_bb0030","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1359\/jbmr.071108","article-title":"Finite element analysis based on in vivo HR-pQCT images of the distal radius is associated with wrist fracture in postmenopausal women","volume":"23","author":"Boutroy","year":"2008","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2021.116282_bb0035","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/s002239900600","article-title":"The mineralization density of iliac crest bone from children with osteogenesis imperfecta","volume":"64","author":"Boyde","year":"1999","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.bone.2021.116282_bb0040","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0167-6636(85)90012-2","article-title":"The relationship between the elasticity tensor and the fabric tensor","volume":"4","author":"Cowin","year":"1985","journal-title":"Mech. Mater."},{"key":"10.1016\/j.bone.2021.116282_bb0045","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1007\/s10237-016-0849-3","article-title":"The effective elastic properties of human trabecular bone may be approximated using micro-finite element analyses of embedded volume elements","volume":"16","author":"Daszkiewicz","year":"2017","journal-title":"Biomech. Model. Mechanobiol."},{"key":"10.1016\/j.bone.2021.116282_bb0050","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1007\/s00198-006-0135-9","article-title":"The population burden of fractures originates in women with osteopenia, not osteoporosis","volume":"17","author":"Pasco","year":"2006","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2021.116282_bb0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmbbm.2020.103866","article-title":"Empirical relationships between bone density and ultimate strength: a literature review","volume":"110","author":"Fleps","year":"2020","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.bone.2021.116282_bb0060","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1002\/jbmr.1592","article-title":"Bone geometry, density, and microarchitecture in the distal radius and tibia in adults with osteogenesis imperfecta type i assessed by high-resolution pQCT","volume":"27","author":"Folkestad","year":"2012","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2021.116282_bb0065","series-title":"Fox, Applied Regressions Analysis and Linear Models","author":"Fox","year":"2016"},{"key":"10.1016\/j.bone.2021.116282_bb0070","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.bone.2017.05.010","article-title":"Quantifying sex, race, and age specific differences in bone microstructure requires measurement of anatomically equivalent regions","volume":"101","author":"Ghasem-Zadeh","year":"2017","journal-title":"Bone"},{"key":"10.1016\/j.bone.2021.116282_bb0075","article-title":"Morphology elasticity relationships using decreasing fabric information of human trabecular bone from three major anatomical locations","volume":"793\u2013800","author":"Gross","year":"2013","journal-title":"Biomech. Model. Mechanobiol."},{"key":"10.1016\/j.bone.2021.116282_bb0080","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1007\/BF00540446","article-title":"Characterization of microstructural anisotropy in cancellous bone using a second rank tensor","volume":"19","author":"Harrigan","year":"1985","journal-title":"J. Mater. Sci."},{"key":"10.1016\/j.bone.2021.116282_bb0085","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.bone.2017.01.003","article-title":"Fast estimation of colles\u2019 fracture load of the distal section of the radius by homogenized finite element analysis based on HR-pQCT","volume":"97","author":"Hosseini","year":"2017","journal-title":"Bone"},{"key":"10.1016\/j.bone.2021.116282_bb0090","article-title":"Compressive strength of iliac bone ECM is not reduced in osteogenesis imperfecta and increases with mineralization","author":"Indermaur","year":"2021","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2021.116282_bb0095","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1007\/s00198-015-3156-4","article-title":"Bone structure assessed by HR-pQCT, TBS and DXL in adult patients with different types of osteogenesis imperfecta","volume":"26","author":"Kocijan","year":"2015","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2021.116282_bb0100","doi-asserted-by":"crossref","first-page":"963","DOI":"10.2307\/2529876","article-title":"Random-effects models for longitudinal data","volume":"38","author":"Laird","year":"1982","journal-title":"Biometrics"},{"key":"10.1016\/j.bone.2021.116282_bb0105","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.bone.2017.02.004","article-title":"Genetic causes and mechanisms of osteogenesis imperfecta.","volume":"102","author":"Lim","year":"2017","journal-title":"Bone"},{"key":"10.1016\/j.bone.2021.116282_bb0110","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1038\/ejhg.2015.81","article-title":"Genetic epidemiology, prevalence, and genotype-phenotype correlations in the swedish population with osteogenesis imperfecta","volume":"23","author":"Lindahl","year":"2015","journal-title":"Eur. J. Hum. Genet."},{"key":"10.1016\/j.bone.2021.116282_bb0115","first-page":"273","article-title":"Generalisation de la theorie de plasticite de w. t. koiter","volume":"1","author":"Mandel","year":"1965"},{"key":"10.1016\/j.bone.2021.116282_bb0120","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s11914-007-0023-z","article-title":"Osteogenesis imperfecta: epidemiology and pathophysiology","volume":"5","author":"Martin","year":"2007","journal-title":"Curr Osteoporos Rep"},{"key":"10.1016\/j.bone.2021.116282_bb0125","article-title":"Techniques for computing fabric tensors: a review","volume":"271\u2013292","author":"Moreno","year":"2014","journal-title":"Math. Vis."},{"key":"10.1016\/j.bone.2021.116282_bb0130","doi-asserted-by":"crossref","first-page":"2393","DOI":"10.1002\/ajmg.a.61366","article-title":"Nosology and classification of genetic skeletal disorders: 2019 revision","volume":"179","author":"Mortier","year":"2019","journal-title":"Am. J. Med. Genet. A"},{"key":"10.1016\/j.bone.2021.116282_bb0135","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.jbiomech.2008.11.028","article-title":"A comparison of enhanced continuum FE with micro FE models of human vertebral bodies","volume":"42","author":"Pahr","year":"2009","journal-title":"Journal of Biomechanics"},{"key":"10.1016\/j.bone.2021.116282_bb0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1115\/1.4028968","article-title":"Comparison of mixed and kinematic uniform boundary conditions in homogenized elasticity of femoral trabecular bone using microfinite element analyses","volume":"137","author":"Panyasantisuk","year":"2015","journal-title":"J. Biomech. Eng."},{"key":"10.1016\/j.bone.2021.116282_bb0145","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.bone.2011.10.003","article-title":"Visual grading of motion induced image degradation in high resolution peripheral computed tomography: impact of image quality on measures of bone density and micro-architecture","volume":"50","author":"Pialat","year":"2012","journal-title":"Bone"},{"key":"10.1016\/j.bone.2021.116282_bb0150","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1007\/s00223-018-0447-8","article-title":"Comparison of bone microarchitecture between adult osteogenesis imperfecta and early-onset osteoporosis","volume":"103","author":"Rolvien","year":"2018","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.bone.2021.116282_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.bone.2020.115575","article-title":"In vivo repeatability of homogenized finite element analysis based on multiple HR-pQCT sections for assessment of distal radius and tibia strength","volume":"141","author":"Schenk","year":"2020","journal-title":"Bone"},{"key":"10.1016\/j.bone.2021.116282_bb0160","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.bonr.2018.04.009","article-title":"Adults with osteogenesis imperfecta: clinical characteristics of 151 patients with a focus on bisphosphonate use and bone density measurements","volume":"8","author":"Scheres","year":"2018","journal-title":"Bone Rep."},{"key":"10.1016\/j.bone.2021.116282_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.bone.2020.115598","article-title":"Conventional finite element models estimate the strength of metastatic human vertebrae despite alterations of the bone\u2019s tissue and structure","volume":"141","author":"Stadelmann","year":"2020","journal-title":"Bone"},{"key":"10.1016\/j.bone.2021.116282_bb0170","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1214\/09-STS313","article-title":"Matching methods for causal inference: a review and a look forward","volume":"25","author":"Stuart","year":"2010","journal-title":"Stat. Sci."},{"key":"10.1016\/j.bone.2021.116282_bb0175","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.metabol.2017.06.001","article-title":"Osteogenesis imperfecta a clinical update","volume":"80","author":"Tournis","year":"2018","journal-title":"Metab. Clin. Exp."},{"key":"10.1016\/j.bone.2021.116282_bb0180","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/s10237-010-0245-3","article-title":"Validation of an HR-pQCT-based homogenized finite element approach using mechanical testing of ultra-distal radius sections","volume":"10","author":"Varga","year":"2011","journal-title":"Biomechanics and Modeling in Mechanobiology"},{"key":"10.1016\/j.bone.2021.116282_bb0185","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/0167-6636(95)00018-6","article-title":"An alternative model for anisotropic elasticity based on fabric tensors","volume":"21","author":"Zysset","year":"1995","journal-title":"Mech. Mater."},{"key":"10.1016\/j.bone.2021.116282_bb0190","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1115\/1.2834756","article-title":"A global relationship between trabecular bone morphology and homogenized elastic properties","volume":"120","author":"Zysset","year":"1998","journal-title":"J. Biomech. Eng."}],"container-title":["Bone"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328221004488?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328221004488?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T17:59:39Z","timestamp":1757613579000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S8756328221004488"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":38,"alternative-id":["S8756328221004488"],"URL":"https:\/\/doi.org\/10.1016\/j.bone.2021.116282","relation":{},"ISSN":["8756-3282"],"issn-type":[{"value":"8756-3282","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fabric-elasticity relationships of tibial trabecular bone are similar in osteogenesis imperfecta and healthy individuals","name":"articletitle","label":"Article Title"},{"value":"Bone","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bone.2021.116282","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"116282"}}