{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T15:39:38Z","timestamp":1787672378742,"version":"build-2736575974"},"reference-count":163,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T00:00:00Z","timestamp":1696550400000},"content-version":"am","delay-in-days":309,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["R01AR073156"],"award-info":[{"award-number":["R01AR073156"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["R01AR077534"],"award-info":[{"award-number":["R01AR077534"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["R21AR076671"],"award-info":[{"award-number":["R21AR076671"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["R01AR069562"],"award-info":[{"award-number":["R01AR069562"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bone"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.bone.2022.116576","type":"journal-article","created":{"date-parts":[[2022,10,3]],"date-time":"2022-10-03T03:40:40Z","timestamp":1664768440000},"page":"116576","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"special_numbering":"C","title":["Osteoclasts: Other functions"],"prefix":"10.1016","volume":"165","author":[{"given":"Kyung-Hyun","family":"Park-Min","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Lorenzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.bone.2022.116576_bb0005","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1038\/nri.2017.53","article-title":"Adult haematopoietic stem cell niches","volume":"17","author":"Crane","year":"2017","journal-title":"Nat. Rev. Immunol."},{"issue":"5","key":"10.1016\/j.bone.2022.116576_bb0010","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1038\/s41580-019-0103-9","article-title":"Haematopoietic stem cell activity and interactions with the niche","volume":"20","author":"Pinho","year":"2019","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"4","key":"10.1016\/j.bone.2022.116576_bb0015","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1038\/ni1331","article-title":"The hematopoietic stem cell in its place","volume":"7","author":"Adams","year":"2006","journal-title":"Nat. Immunol."},{"issue":"13","key":"10.1016\/j.bone.2022.116576_bb0020","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1016\/j.devcel.2021.05.018","article-title":"Niches that regulate stem cells and hematopoiesis in adult bone marrow","volume":"56","author":"Comazzetto","year":"2021","journal-title":"Dev. Cell"},{"issue":"4","key":"10.1016\/j.bone.2022.116576_bb0025","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1017\/S1461145713001569","article-title":"Decreased global methylation in patients with bipolar disorder who respond to lithium","volume":"17","author":"Huzayyin","year":"2014","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.bone.2022.116576_bb0030","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/bonekey.2012.46","article-title":"Osteoclasts and hematopoiesis","volume":"1","author":"Teti","year":"2012","journal-title":"Bonekey Rep."},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0035","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.bone.2007.08.029","article-title":"Genetics, pathogenesis and complications of osteopetrosis","volume":"42","author":"Del Fattore","year":"2008","journal-title":"Bone"},{"issue":"5","key":"10.1016\/j.bone.2022.116576_bb0040","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1182\/blood-2010-05-282855","article-title":"Inhibition of osteoclast function reduces hematopoietic stem cell numbers in vivo","volume":"117","author":"Lymperi","year":"2011","journal-title":"Blood"},{"issue":"3","key":"10.1016\/j.bone.2022.116576_bb0045","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1084\/jem.20110994","article-title":"Osteoclasts promote the formation of hematopoietic stem cell niches in the bone marrow","volume":"209","author":"Mansour","year":"2012","journal-title":"J. Exp. Med."},{"issue":"6274","key":"10.1016\/j.bone.2022.116576_bb0050","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1038\/345442a0","article-title":"The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene","volume":"345","author":"Yoshida","year":"1990","journal-title":"Nature"},{"issue":"21","key":"10.1016\/j.bone.2022.116576_bb0055","doi-asserted-by":"crossref","first-page":"12517","DOI":"10.1074\/jbc.271.21.12517","article-title":"Proteolytic activity of human osteoclast cathepsin K. Expression, purification, activation, and substrate identification","volume":"271","author":"Bossard","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bone.2022.116576_bb0060","doi-asserted-by":"crossref","first-page":"433","DOI":"10.3389\/fcell.2020.00433","article-title":"Cathepsin K: the action in and beyond bone","volume":"8","author":"Dai","year":"2020","journal-title":"Front. Cell Dev. Biol."},{"issue":"7","key":"10.1016\/j.bone.2022.116576_bb0065","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1038\/nrd.2016.132","article-title":"Two pioneering osteoporosis drugs finally approach approval","volume":"15","author":"Garber","year":"2016","journal-title":"Nat. Rev. Drug Discov."},{"issue":"6","key":"10.1016\/j.bone.2022.116576_bb0070","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1038\/nm1417","article-title":"Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells","volume":"12","author":"Kollet","year":"2006","journal-title":"Nat. Med."},{"issue":"11","key":"10.1016\/j.bone.2022.116576_bb0075","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1084\/jem.20101890","article-title":"Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilization","volume":"208","author":"Miyamoto","year":"2011","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.bone.2022.116576_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2020.112260","article-title":"Matrix metalloproteinase-9 (MMP-9) and its inhibitors in cancer: a minireview","volume":"194","author":"Mondal","year":"2020","journal-title":"Eur. J. Med. Chem."},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0085","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.yexcr.2006.10.001","article-title":"RANK ligand signaling modulates the matrix metalloproteinase-9 gene expression during osteoclast differentiation","volume":"313","author":"Sundaram","year":"2007","journal-title":"Exp. Cell Res."},{"issue":"5","key":"10.1016\/j.bone.2022.116576_bb0090","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/S0092-8674(02)00754-7","article-title":"Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand","volume":"109","author":"Heissig","year":"2002","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0095","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1182\/blood-2003-04-1115","article-title":"Neutrophil-derived MMP-9 mediates synergistic mobilization of hematopoietic stem and progenitor cells by the combination of G-CSF and the chemokines GRObeta\/CXCL2 and GRObetaT\/CXCL2delta4","volume":"103","author":"Pelus","year":"2004","journal-title":"Blood"},{"issue":"4","key":"10.1016\/j.bone.2022.116576_bb0100","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1634\/stemcells.21-4-417","article-title":"Use of matrix metalloproteinase (MMP)-9 knockout mice demonstrates that MMP-9 activity is not absolutely required for G-CSF or Flt-3 ligand-induced hematopoietic progenitor cell mobilization or engraftment","volume":"21","author":"Robinson","year":"2003","journal-title":"Stem Cells"},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0105","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1182\/blood-2003-05-1589","article-title":"Characterization of hematopoietic progenitor mobilization in protease-deficient mice","volume":"104","author":"Levesque","year":"2004","journal-title":"Blood"},{"issue":"7076","key":"10.1016\/j.bone.2022.116576_bb0110","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/nature04247","article-title":"Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor","volume":"439","author":"Adams","year":"2006","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.bone.2022.116576_bb0115","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1182\/blood-2010-05-286294","article-title":"Pharmacologic modulation of the calcium-sensing receptor enhances hematopoietic stem cell lodgment in the adult bone marrow","volume":"117","author":"Lam","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.bone.2022.116576_bb0120","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.semcdb.2021.05.014","article-title":"Interaction between bone and immune cells: implications for postmenopausal osteoporosis","volume":"123","author":"Fischer","year":"2022","journal-title":"Semin. Cell Dev. Biol."},{"issue":"6","key":"10.1016\/j.bone.2022.116576_bb0125","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.immuni.2004.05.001","article-title":"Cellular niches controlling B lymphocyte behavior within bone marrow during development","volume":"20","author":"Tokoyoda","year":"2004","journal-title":"Immunity"},{"key":"10.1016\/j.bone.2022.116576_bb0130","doi-asserted-by":"crossref","first-page":"301","DOI":"10.3389\/fimmu.2015.00301","article-title":"CXCL12\/SDF-1 and CXCR4","volume":"6","author":"Nagasawa","year":"2015","journal-title":"Front. Immunol."},{"issue":"4","key":"10.1016\/j.bone.2022.116576_bb0135","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1084\/jem.181.4.1519","article-title":"Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine","volume":"181","author":"von Freeden-Jeffry","year":"1995","journal-title":"J. Exp. Med."},{"issue":"7","key":"10.1016\/j.bone.2022.116576_bb0140","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1038\/cr.2011.21","article-title":"Osteoclast activity modulates B-cell development in the bone marrow","volume":"21","author":"Mansour","year":"2011","journal-title":"Cell Res."},{"issue":"4","key":"10.1016\/j.bone.2022.116576_bb0145","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1038\/nri2062","article-title":"Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems","volume":"7","author":"Takayanagi","year":"2007","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bone.2022.116576_bb0150","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/j.0105-2896.2005.00340.x","article-title":"Osteoimmunology","volume":"208","author":"Lorenzo","year":"2005","journal-title":"Immunol. Rev."},{"issue":"4","key":"10.1016\/j.bone.2022.116576_bb0155","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1210\/er.2007-0038","article-title":"Osteoimmunology: interactions of the bone and immune system","volume":"29","author":"Lorenzo","year":"2008","journal-title":"Endocr. Rev."},{"issue":"9","key":"10.1016\/j.bone.2022.116576_bb0160","doi-asserted-by":"crossref","first-page":"5477","DOI":"10.4049\/jimmunol.0803897","article-title":"Cross-presentation by osteoclasts induces FoxP3 in CD8+ T cells","volume":"182","author":"Kiesel","year":"2009","journal-title":"J. Immunol."},{"issue":"2","key":"10.1016\/j.bone.2022.116576_bb0165","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1182\/blood-2009-11-255026","article-title":"Cross talk between the bone and immune systems: osteoclasts function as antigen-presenting cells and activate CD4+ and CD8+ T cells","volume":"116","author":"Li","year":"2010","journal-title":"Blood"},{"issue":"9","key":"10.1016\/j.bone.2022.116576_bb0170","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.it.2006.07.004","article-title":"T cells and their partners: the chemokine dating agency","volume":"27","author":"Viola","year":"2006","journal-title":"Trends Immunol."},{"issue":"11","key":"10.1016\/j.bone.2022.116576_bb0175","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1038\/nrd.2018.148","article-title":"Regulatory T cells in the treatment of disease","volume":"17","author":"Sharabi","year":"2018","journal-title":"Nat. Rev. Drug Discov."},{"issue":"5","key":"10.1016\/j.bone.2022.116576_bb0180","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.cell.2008.05.009","article-title":"Regulatory T cells and immune tolerance","volume":"133","author":"Sakaguchi","year":"2008","journal-title":"Cell"},{"issue":"4","key":"10.1016\/j.bone.2022.116576_bb0185","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/ni909","article-title":"An essential role for scurfin in CD4+CD25+ T regulatory cells","volume":"4","author":"Khattri","year":"2003","journal-title":"Nat. Immunol."},{"issue":"4","key":"10.1016\/j.bone.2022.116576_bb0190","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1038\/ni904","article-title":"Foxp3 programs the development and function of CD4+CD25+ regulatory T cells","volume":"4","author":"Fontenot","year":"2003","journal-title":"Nat. Immunol."},{"issue":"3","key":"10.1016\/j.bone.2022.116576_bb0195","doi-asserted-by":"crossref","first-page":"726","DOI":"10.4049\/jimmunol.1600253","article-title":"Osteoclast-primed Foxp3+ CD8 T cells induce T-bet, eomesodermin, and IFN-gamma to regulate bone resorption","volume":"197","author":"Shashkova","year":"2016","journal-title":"J. Immunol."},{"issue":"6","key":"10.1016\/j.bone.2022.116576_bb0200","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0038199","article-title":"Osteoclast activated FoxP3+ CD8+ T-cells suppress bone resorption in vitro","volume":"7","author":"Buchwald","year":"2012","journal-title":"PloS one"},{"issue":"10","key":"10.1016\/j.bone.2022.116576_bb0205","doi-asserted-by":"crossref","first-page":"1899","DOI":"10.1002\/jbmr.2868","article-title":"Inflammatory osteoclasts prime TNF\u03b1-producing CD4(+) T cells and express CX(3) CR1","volume":"31","author":"Ib\u00e1\u00f1ez","year":"2016","journal-title":"J. Bone Miner. Res."},{"issue":"12","key":"10.1016\/j.bone.2022.116576_bb0210","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1016\/j.febslet.2015.04.008","article-title":"Deficiency of cathepsin K prevents inflammation and bone erosion in rheumatoid arthritis and periodontitis and reveals its shared osteoimmune role","volume":"589","author":"Hao","year":"2015","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bone.2022.116576_bb0215","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1146\/annurev.immunol.23.021704.115526","article-title":"NK cell recognition","volume":"23","author":"Lanier","year":"2005","journal-title":"Annu. Rev. Immunol."},{"issue":"3","key":"10.1016\/j.bone.2022.116576_bb0220","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1038\/s41573-019-0052-1","article-title":"NK cells for cancer immunotherapy","volume":"19","author":"Shimasaki","year":"2020","journal-title":"Nat. Rev. Drug Discov."},{"issue":"12","key":"10.1016\/j.bone.2022.116576_bb0225","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.it.2013.07.005","article-title":"Location and cellular stages of natural killer cell development","volume":"34","author":"Yu","year":"2013","journal-title":"Trends Immunol."},{"issue":"4","key":"10.1016\/j.bone.2022.116576_bb0230","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.immuni.2015.09.013","article-title":"Natural killer cell memory","volume":"43","author":"O'Sullivan","year":"2015","journal-title":"Immunity"},{"issue":"24","key":"10.1016\/j.bone.2022.116576_bb0235","doi-asserted-by":"crossref","first-page":"20002","DOI":"10.18632\/oncotarget.4755","article-title":"Bisphosphonate-induced differential modulation of immune cell function in gingiva and bone marrow in vivo: role in osteoclast-mediated NK cell activation","volume":"6","author":"Tseng","year":"2015","journal-title":"Oncotarget"},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0240","doi-asserted-by":"crossref","first-page":"20363","DOI":"10.1038\/s41598-020-76702-1","article-title":"Osteoclast-expanded super-charged NK-cells preferentially select and expand CD8+ T cells","volume":"10","author":"Kaur","year":"2020","journal-title":"Sci. Rep."},{"issue":"6","key":"10.1016\/j.bone.2022.116576_bb0245","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0038500","article-title":"Infection of RANKL-primed RAW-D macrophages with porphyromonas gingivalis promotes osteoclastogenesis in a TNF-\u03b1-independent manner","volume":"7","author":"Kukita","year":"2012","journal-title":"PloS one"},{"issue":"11","key":"10.1016\/j.bone.2022.116576_bb0250","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1016\/j.spinee.2019.05.002","article-title":"Spinal tuberculosis: a comprehensive review for the modern spine surgeon","volume":"19","author":"Khanna","year":"2019","journal-title":"Spine J."},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0255","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/2049-632X.12082","article-title":"Mycobacterium tuberculosis escapes from the phagosomes of infected human osteoclasts reprograms osteoclast development via dysregulation of cytokines and chemokines","volume":"70","author":"Hoshino","year":"2014","journal-title":"Pathog. Dis."},{"key":"10.1016\/j.bone.2022.116576_bb0260","doi-asserted-by":"crossref","first-page":"42918","DOI":"10.1038\/srep42918","article-title":"Interaction of cutibacterium ( formerly Propionibacterium) acnes with bone cells: a step toward understanding bone and joint infection development","volume":"7","author":"Aubin","year":"2017","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.bone.2022.116576_bb0265","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1128\/CMR.00111-13","article-title":"Prosthetic joint infection","volume":"27","author":"Tande","year":"2014","journal-title":"Clin. Microbiol. Rev."},{"issue":"9431","key":"10.1016\/j.bone.2022.116576_bb0270","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S0140-6736(04)16727-5","article-title":"Osteomyelitis","volume":"364","author":"Lew","year":"2004","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.bone.2022.116576_bb0275","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.02447-19","article-title":"Staphylococcus aureus infects osteoclasts and replicates intracellularly","volume":"10","author":"Krauss","year":"2019","journal-title":"MBio"},{"key":"10.1016\/j.bone.2022.116576_bb0280","doi-asserted-by":"crossref","first-page":"13601","DOI":"10.1038\/ncomms13601","article-title":"Blood flow controls bone vascular function and osteogenesis","volume":"7","author":"Ramasamy","year":"2016","journal-title":"Nat. Commun."},{"issue":"19","key":"10.1016\/j.bone.2022.116576_bb0285","doi-asserted-by":"crossref","first-page":"13491","DOI":"10.1074\/jbc.M708055200","article-title":"VEGF-C, a lymphatic growth factor, is a RANKL target gene in osteoclasts that enhances osteoclastic bone resorption through an autocrine mechanism","volume":"283","author":"Zhang","year":"2008","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.bone.2022.116576_bb0290","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1038\/s42255-018-0016-5","article-title":"A network of trans-cortical capillaries as mainstay for blood circulation in long bones","volume":"1","author":"Gruneboom","year":"2019","journal-title":"Nat. Metab."},{"issue":"11 Suppl A","key":"10.1016\/j.bone.2022.116576_bb0295","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1302\/0301-620X.95B11.32644","article-title":"Osteonecrosis of the femoral head: the total hip replacement solution","volume":"95-B","author":"Issa","year":"2013","journal-title":"Bone Joint J."},{"issue":"983","key":"10.1016\/j.bone.2022.116576_bb0300","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1038\/206489a0","article-title":"Suggested sequential mode of control of changes in cell behaviour in adult bone remodelling","volume":"206","author":"Hattner","year":"1965","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0305","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0221-8747(82)90002-9","article-title":"The coupling of bone formation to bone resorption: a critical analysis of the concept and of its relevance to the pathogenesis of osteoporosis","volume":"4","author":"Parfitt","year":"1982","journal-title":"Metab. Bone Dis. Relat. Res."},{"issue":"9","key":"10.1016\/j.bone.2022.116576_bb0310","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1038\/nrendo.2013.137","article-title":"Osteopetrosis: genetics, treatment and new insights into osteoclast function","volume":"9","author":"Sobacchi","year":"2013","journal-title":"Nat. Rev. Endocrinol."},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0315","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.ajhg.2008.06.015","article-title":"Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations","volume":"83","author":"Guerrini","year":"2008","journal-title":"Am. J. Hum. Genet."},{"issue":"4","key":"10.1016\/j.bone.2022.116576_bb0320","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1136\/jmg.2005.036673","article-title":"Clinical, genetic, and cellular analysis of 49 osteopetrotic patients: implications for diagnosis and treatment","volume":"43","author":"Del Fattore","year":"2006","journal-title":"J. Med. Genet."},{"issue":"9","key":"10.1016\/j.bone.2022.116576_bb0325","doi-asserted-by":"crossref","first-page":"7409","DOI":"10.1074\/jbc.R400029200","article-title":"Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability","volume":"280","author":"Rifkin","year":"2005","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.bone.2022.116576_bb0330","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/0006-291X(89)92795-2","article-title":"Activation of the bone-derived latent TGF beta complex by isolated osteoclasts","volume":"158","author":"Oreffo","year":"1989","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bone.2022.116576_bb0335","doi-asserted-by":"crossref","first-page":"2024","DOI":"10.1073\/pnas.84.7.2024","article-title":"Modulation of type beta transforming growth factor activity in bone cultures by osteotropic hormones","volume":"84","author":"Pfeilschifter","year":"1987","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bone.2022.116576_bb0340","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1002\/jbmr.5650090402","article-title":"Osteoclast synthesis and secretion and activation of latent transforming growth factor \u00e1","volume":"9","author":"Oursler","year":"1994","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2022.116576_bb0345","doi-asserted-by":"crossref","first-page":"2306","DOI":"10.1210\/endo-119-5-2306","article-title":"Human platelet-derived transforming growth factor-beta stimulates parameters of bone growth in fetal rat calvariae","volume":"119","author":"Centrella","year":"1986","journal-title":"Endocrinology"},{"key":"10.1016\/j.bone.2022.116576_bb0350","doi-asserted-by":"crossref","first-page":"2869","DOI":"10.1016\/S0021-9258(18)61587-X","article-title":"Transforming growth factor beta is a bifunctional regulator of replication and collagen synthesis in osteoblast-enriched cell cultures from fetal rat bone","volume":"262","author":"Centrella","year":"1987","journal-title":"J. Biol. Chem."},{"issue":"7","key":"10.1016\/j.bone.2022.116576_bb0355","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1038\/nm.1979","article-title":"TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation","volume":"15","author":"Tang","year":"2009","journal-title":"Nat. Med."},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0360","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.bone.2013.07.023","article-title":"Transforming growth factor beta 1 induces CXCL16 and leukemia inhibitory factor expression in osteoclasts to modulate migration of osteoblast progenitors","volume":"57","author":"Ota","year":"2013","journal-title":"Bone"},{"key":"10.1016\/j.bone.2022.116576_bb0365","first-page":"24","article-title":"Transforming growth factor-{beta} coordinately induces suppressor of cytokine signaling 3 and leukemia inhibitory factor to suppress osteoclast apoptosis","volume":"24","author":"Ruan","year":"2010","journal-title":"Endocrinology"},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0370","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1002\/jbmr.2586","article-title":"Osteoclast TGF-\u03b2 receptor signaling induces Wnt1 secretion and couples bone resorption to bone formation","volume":"31","author":"Weivoda","year":"2016","journal-title":"J. Bone Miner. Res."},{"issue":"10","key":"10.1016\/j.bone.2022.116576_bb0375","doi-asserted-by":"crossref","first-page":"3745","DOI":"10.1210\/en.2013-1272","article-title":"TGF-\u03b2 induces Wnt10b in osteoclasts from female mice to enhance coupling to osteoblasts","volume":"154","author":"Ota","year":"2013","journal-title":"Endocrinology"},{"issue":"Suppl. 1","key":"10.1016\/j.bone.2022.116576_bb0380","first-page":"49","article-title":"Growth hormone and bone","volume":"36","author":"Bouillon","year":"1991","journal-title":"Horm. Res."},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0385","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1210\/endo-122-1-254","article-title":"Insulin-like growth factor I has independent effects on bone matrix formation and cell replication","volume":"122","author":"Hock","year":"1988","journal-title":"Endocrinology"},{"key":"10.1016\/j.bone.2022.116576_bb0390","doi-asserted-by":"crossref","first-page":"6","DOI":"10.3389\/fendo.2013.00006","article-title":"Anabolic effects of IGF-1 signaling on the skeleton","volume":"4","author":"Tahimic","year":"2013","journal-title":"Front. Endocrinol. (Lausanne)"},{"issue":"2","key":"10.1016\/j.bone.2022.116576_bb0395","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/s00109-013-1084-3","article-title":"Function of matrix IGF-1 in coupling bone resorption and formation","volume":"92","author":"Crane","year":"2014","journal-title":"J. Mol. Med. (Berl)"},{"issue":"7","key":"10.1016\/j.bone.2022.116576_bb0400","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1038\/nm.2793","article-title":"Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells","volume":"18","author":"Xian","year":"2012","journal-title":"Nat. Med."},{"issue":"6","key":"10.1016\/j.bone.2022.116576_bb0405","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.133113","article-title":"Osteoclast-derived IGF1 is required for pagetic lesion formation in vivo","volume":"5","author":"Miyagawa","year":"2020","journal-title":"JCI Insight"},{"issue":"3\u20134","key":"10.1016\/j.bone.2022.116576_bb0410","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1002\/jcb.29861","article-title":"Increased S1P expression in osteoclasts enhances bone formation in an animal model of Paget's disease","volume":"122","author":"Nagata","year":"2021","journal-title":"J. Cell. Biochem."},{"issue":"3","key":"10.1016\/j.bone.2022.116576_bb0415","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1172\/JCI82012","article-title":"Measles virus nucleocapsid protein increases osteoblast differentiation in Paget's disease","volume":"126","author":"Teramachi","year":"2016","journal-title":"J. Clin. Invest."},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0420","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s00223-014-9865-4","article-title":"A comparison of osteoclast-rich and osteoclast-poor osteopetrosis in adult mice sheds light on the role of the osteoclast in coupling bone resorption and bone formation","volume":"95","author":"Thudium","year":"2014","journal-title":"Calcif. Tissue Int."},{"issue":"11","key":"10.1016\/j.bone.2022.116576_bb0425","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1038\/nm.3668","article-title":"PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis","volume":"20","author":"Xie","year":"2014","journal-title":"Nat. Med."},{"key":"10.1016\/j.bone.2022.116576_bb0430","first-page":"30","article-title":"Non-resorbing osteoclasts induce migration and osteogenic differentiation of mesenchymal stem cells","volume":"30","author":"Kreja","year":"2009","journal-title":"J. Cell. Biochem."},{"issue":"2","key":"10.1016\/j.bone.2022.116576_bb0435","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1359\/jbmr.2002.17.2.257","article-title":"Platelet-derived growth factor BB secreted from osteoclasts acts as an osteoblastogenesis inhibitory factor","volume":"17","author":"Kubota","year":"2002","journal-title":"J. Bone Miner. Res."},{"issue":"10","key":"10.1016\/j.bone.2022.116576_bb0440","doi-asserted-by":"crossref","first-page":"4115","DOI":"10.1210\/endo.137.10.8828465","article-title":"Expression and growth factor regulation of platelet-derived growth factor B transcripts in primary osteoblast cell cultures","volume":"137","author":"Rydziel","year":"1996","journal-title":"Endocrinology"},{"key":"10.1016\/j.bone.2022.116576_bb0445","doi-asserted-by":"crossref","first-page":"12665","DOI":"10.1016\/S0021-9258(18)67143-1","article-title":"Growth factors in bone matrix. Isolation of multiple types by affinity chromatography on heparin-sepharose","volume":"261","author":"Hauschka","year":"1986","journal-title":"J. Biol. Chem."},{"issue":"6","key":"10.1016\/j.bone.2022.116576_bb0450","doi-asserted-by":"crossref","first-page":"2578","DOI":"10.1172\/JCI98857","article-title":"Macrophage-lineage TRAP+ cells recruit periosteum-derived cells for periosteal osteogenesis and regeneration","volume":"129","author":"Gao","year":"2019","journal-title":"J. Clin. Invest."},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0455","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/s41413-021-00161-1","article-title":"An antibody against Siglec-15 promotes bone formation and fracture healing by increasing TRAP(+) mononuclear cells and PDGF-BB secretion","volume":"9","author":"Zhen","year":"2021","journal-title":"Bone Res."},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0460","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1038\/s41413-020-00121-1","article-title":"Osteoclast-derived apoptotic bodies couple bone resorption and formation in bone remodeling","volume":"9","author":"Ma","year":"2021","journal-title":"Bone Res."},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0465","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/nyas.13629","article-title":"A novel role for cathepsin K in periosteal osteoclast precursors during fracture repair","volume":"1415","author":"Walia","year":"2018","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"6","key":"10.1016\/j.bone.2022.116576_bb0470","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0179248","article-title":"Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB","volume":"12","author":"Gao","year":"2017","journal-title":"PloS one"},{"issue":"7","key":"10.1016\/j.bone.2022.116576_bb0475","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1038\/nri1650","article-title":"Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network","volume":"5","author":"Rosen","year":"2005","journal-title":"Nat. Rev. Immunol."},{"issue":"52","key":"10.1016\/j.bone.2022.116576_bb0480","doi-asserted-by":"crossref","first-page":"20764","DOI":"10.1073\/pnas.0805133106","article-title":"Regulation of bone formation by osteoclasts involves Wnt\/BMP signaling and the chemokine sphingosine-1-phosphate","volume":"105","author":"Pederson","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S A"},{"issue":"24","key":"10.1016\/j.bone.2022.116576_bb0485","doi-asserted-by":"crossref","first-page":"5840","DOI":"10.1038\/sj.emboj.7601430","article-title":"Sphingosine 1-phosphate as a regulator of osteoclast differentiation and osteoclast-osteoblast coupling","volume":"25","author":"Ryu","year":"2006","journal-title":"Eur. Mol. Biol. J."},{"issue":"5279","key":"10.1016\/j.bone.2022.116576_bb0490","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1126\/science.273.5279.1236","article-title":"Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency","volume":"273","author":"Gelb","year":"1996","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.bone.2022.116576_bb0495","first-page":"666","article-title":"Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation","volume":"123","author":"Lotinun","year":"2013","journal-title":"J. Clin. Invest."},{"issue":"51","key":"10.1016\/j.bone.2022.116576_bb0500","doi-asserted-by":"crossref","first-page":"17713","DOI":"10.1074\/jbc.RA120.013573","article-title":"Hdac3 regulates bone modeling by suppressing osteoclast responsiveness to RANKL","volume":"295","author":"Molstad","year":"2020","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bone.2022.116576_bb0505","doi-asserted-by":"crossref","first-page":"5215","DOI":"10.1038\/ncomms6215","article-title":"Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts","volume":"5","author":"Keller","year":"2014","journal-title":"Nat. Commun."},{"issue":"7237","key":"10.1016\/j.bone.2022.116576_bb0510","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1038\/nature07713","article-title":"Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis","volume":"458","author":"Ishii","year":"2009","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.bone.2022.116576_bb0515","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1038\/s41591-018-0005-y","article-title":"Targeting sphingosine-1-phosphate lyase as an anabolic therapy for bone loss","volume":"24","author":"Weske","year":"2018","journal-title":"Nat. Med."},{"issue":"24","key":"10.1016\/j.bone.2022.116576_bb0520","doi-asserted-by":"crossref","first-page":"5840","DOI":"10.1038\/sj.emboj.7601430","article-title":"Sphingosine 1-phosphate as a regulator of osteoclast differentiation and osteoclast-osteoblast coupling","volume":"25","author":"Ryu","year":"2006","journal-title":"EMBO J."},{"issue":"52","key":"10.1016\/j.bone.2022.116576_bb0525","doi-asserted-by":"crossref","first-page":"20764","DOI":"10.1073\/pnas.0805133106","article-title":"Regulation of bone formation by osteoclasts involves Wnt\/BMP signaling and the chemokine sphingosine-1-phosphate","volume":"105","author":"Pederson","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"2","key":"10.1016\/j.bone.2022.116576_bb0530","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.bone.2013.04.008","article-title":"Sphingosine-1-phosphate promotes the nuclear translocation of beta-catenin and thereby induces osteoprotegerin gene expression in osteoblast-like cell lines","volume":"55","author":"Matsuzaki","year":"2013","journal-title":"Bone"},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0535","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.bbrc.2012.05.130","article-title":"Sphingosine 1-phosphate receptor activation enhances BMP-2-induced osteoblast differentiation","volume":"423","author":"Sato","year":"2012","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"5573","key":"10.1016\/j.bone.2022.116576_bb0540","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1126\/science.1071809","article-title":"Signal transduction by the TGF-beta superfamily","volume":"296","author":"Attisano","year":"2002","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.bone.2022.116576_bb0545","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1302\/0301-620X.88B6.17524","article-title":"The role of growth factors and related agents in accelerating fracture healing","volume":"88","author":"Simpson","year":"2006","journal-title":"J. Bone Joint Surg. (Br.)"},{"key":"10.1016\/j.bone.2022.116576_bb0550","article-title":"Bone morphogenetic proteins: their role in regulating osteoclast differentiation","volume":"10","author":"Huntley","year":"2019","journal-title":"Bone Rep."},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0555","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.gendis.2014.07.005","article-title":"Bone morphogenetic protein (BMP) signaling in development and human diseases","volume":"1","author":"Wang","year":"2014","journal-title":"Genes Dis."},{"issue":"6","key":"10.1016\/j.bone.2022.116576_bb0560","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1369\/jhc.2008.950394","article-title":"Expression and synthesis of bone morphogenetic proteins by osteoclasts: a possible path to anabolic bone remodeling","volume":"56","author":"Garimella","year":"2008","journal-title":"J. Histochem. Cytochem."},{"issue":"10","key":"10.1016\/j.bone.2022.116576_bb0565","doi-asserted-by":"crossref","first-page":"2977","DOI":"10.1242\/dev.122.10.2977","article-title":"Mice deficient for BMP2 are nonviable and have defects in amnion\/chorion and cardiac development","volume":"122","author":"Zhang","year":"1996","journal-title":"Development"},{"issue":"42","key":"10.1016\/j.bone.2022.116576_bb0570","doi-asserted-by":"crossref","first-page":"35704","DOI":"10.1074\/jbc.M505166200","article-title":"Involvement of endogenous bone morphogenetic protein (BMP) 2 and BMP6 in bone formation","volume":"280","author":"Kugimiya","year":"2005","journal-title":"J. Biol. Chem."},{"issue":"22","key":"10.1016\/j.bone.2022.116576_bb0575","doi-asserted-by":"crossref","first-page":"2795","DOI":"10.1101\/gad.9.22.2795","article-title":"A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye","volume":"9","author":"Dudley","year":"1995","journal-title":"Genes Dev."},{"issue":"3","key":"10.1016\/j.bone.2022.116576_bb0580","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/0092-8674(92)90510-J","article-title":"The mouse short ear skeletal morphogenesis locus is associated with defects in a bone morphogenetic member of the TGF beta superfamily","volume":"71","author":"Kingsley","year":"1992","journal-title":"Cell"},{"issue":"4","key":"10.1016\/j.bone.2022.116576_bb0585","first-page":"445","article-title":"Long bone geometry and strength in adult BMP-5 deficient mice","volume":"16","author":"Mikic","year":"1995","journal-title":"Bone"},{"issue":"5","key":"10.1016\/j.bone.2022.116576_bb0590","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1002\/jor.20359","article-title":"Distinct roles of bone morphogenetic proteins in osteogenic differentiation of mesenchymal stem cells","volume":"25","author":"Luu","year":"2007","journal-title":"J. Orthop. Res."},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0595","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1210\/me.2011-1168","article-title":"BMP3 suppresses osteoblast differentiation of bone marrow stromal cells via interaction with Acvr2b","volume":"26","author":"Kokabu","year":"2012","journal-title":"Mol. Endocrinol."},{"issue":"12","key":"10.1016\/j.bone.2022.116576_bb0600","doi-asserted-by":"crossref","first-page":"877","DOI":"10.7326\/0003-4819-158-12-201306180-00005","article-title":"Safety and effectiveness of recombinant human bone morphogenetic protein-2 for spinal fusion: a meta-analysis of individual-participant data","volume":"158","author":"Simmonds","year":"2013","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.bone.2022.116576_bb0605","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2020.586031","article-title":"The bone morphogenetic protein pathway: the osteoclastic perspective","volume":"8","author":"Lademann","year":"2020","journal-title":"Front. Cell Dev. Biol."},{"issue":"11","key":"10.1016\/j.bone.2022.116576_bb0610","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1002\/jbmr.5650101110","article-title":"Stimulatory effect of bone morphogenetic protein-2 on osteoclast-like cell formation and bone-resorbing activity","volume":"10","author":"Kanatani","year":"1995","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2022.116576_bb0615","doi-asserted-by":"crossref","DOI":"10.1016\/j.cyto.2021.155655","article-title":"Influences of the IL-6 cytokine family on bone structure and function","volume":"146","author":"Sims","year":"2021","journal-title":"Cytokine"},{"issue":"12","key":"10.1016\/j.bone.2022.116576_bb0620","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1359\/jbmr.080706","article-title":"Cardiotrophin-1 is an osteoclast-derived stimulus of bone formation required for Normal bone remodeling","volume":"23","author":"Walker","year":"2008","journal-title":"J. Bone Miner. Res."},{"issue":"40568","key":"10.1016\/j.bone.2022.116576_bb0625","article-title":"Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice","volume":"4","author":"Walker","year":"2010","journal-title":"J. Clin. Invest."},{"issue":"6","key":"10.1016\/j.bone.2022.116576_bb0630","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1006\/cyto.1999.0635","article-title":"Stimulation of osteoclast differentiation in vitro by mouse oncostatin M, leukaemia inhibitory factor, cardiotrophin-1 and interleukin 6: synergy with dexamethasone","volume":"12","author":"Richards","year":"2000","journal-title":"Cytokine"},{"issue":"2","key":"10.1016\/j.bone.2022.116576_bb0635","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1111\/odi.13745","article-title":"HIF-1\u03b1 regulates osteoclast activation and mediates osteogenesis during mandibular bone repair via CT-1","volume":"28","author":"Tian","year":"2022","journal-title":"Oral Dis."},{"issue":"9","key":"10.1016\/j.bone.2022.116576_bb0640","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0073266","article-title":"Cord blood-derived macrophage-lineage cells rapidly stimulate osteoblastic maturation in mesenchymal stem cells in a glycoprotein-130 dependent manner","volume":"8","author":"Fernandes","year":"2013","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.bone.2022.116576_bb0645","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1002\/stem.1040","article-title":"Induction of osteogenesis in mesenchymal stem cells by activated monocytes\/macrophages depends on oncostatin M signaling","volume":"30","author":"Guihard","year":"2012","journal-title":"Stem Cells"},{"key":"10.1016\/j.bone.2022.116576_bb0650","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1210\/endo.132.3.8440191","article-title":"The effect of leukemia inhibitory factor on bone in vivo","volume":"132","author":"Cornish","year":"1993","journal-title":"Endocrinology"},{"issue":"3","key":"10.1016\/j.bone.2022.116576_bb0655","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1002\/jbmr.1485","article-title":"Contrasting roles of leukemia inhibitory factor in murine bone development and remodeling involve region-specific changes in vascularization","volume":"27","author":"Poulton","year":"2012","journal-title":"J. Bone Miner. Res."},{"issue":"10","key":"10.1016\/j.bone.2022.116576_bb0660","doi-asserted-by":"crossref","first-page":"2074","DOI":"10.1002\/jbmr.3175","article-title":"Bone formation is coupled to resorption via suppression of sclerostin expression by osteoclasts","volume":"32","author":"Koide","year":"2017","journal-title":"J. Bone Miner. Res."},{"issue":"2","key":"10.1016\/j.bone.2022.116576_bb0665","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1161\/01.RES.0000154262.07264.12","article-title":"Collagen triple helix repeat containing 1, a novel secreted protein in injured and diseased arteries, inhibits collagen expression and promotes cell migration","volume":"96","author":"Pyagay","year":"2005","journal-title":"Circ. Res."},{"issue":"6","key":"10.1016\/j.bone.2022.116576_bb0670","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.tcm.2007.05.004","article-title":"The role of collagen triple helix repeat containing 1 in injured arteries, collagen expression, and transforming growth factor beta signaling","volume":"17","author":"LeClair","year":"2007","journal-title":"Trends Cardiovasc. Med."},{"issue":"9","key":"10.1016\/j.bone.2022.116576_bb0675","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0003174","article-title":"Cthrc1 is a positive regulator of osteoblastic bone formation","volume":"3","author":"Kimura","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.bone.2022.116576_bb0680","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.bone.2017.01.022","article-title":"Inhibition of osteoclast differentiation and collagen antibody-induced arthritis by CTHRC1","volume":"97","author":"Jin","year":"2017","journal-title":"Bone"},{"issue":"9","key":"10.1016\/j.bone.2022.116576_bb0685","doi-asserted-by":"crossref","first-page":"3914","DOI":"10.1172\/JCI69493","article-title":"Osteoclast-secreted CTHRC1 in the coupling of bone resorption to formation","volume":"123","author":"Takeshita","year":"2013","journal-title":"J. Clin. Invest."},{"issue":"8","key":"10.1016\/j.bone.2022.116576_bb0690","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1002\/jbmr.3436","article-title":"WAIF1 is a cell-surface CTHRC1 binding protein coupling bone resorption and formation","volume":"33","author":"Matsuoka","year":"2018","journal-title":"J. Bone Miner. Res."},{"issue":"10","key":"10.1016\/j.bone.2022.116576_bb0695","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0047142","article-title":"Cthrc1, a novel circulating hormone regulating metabolism","volume":"7","author":"Stohn","year":"2012","journal-title":"PLoS One"},{"issue":"31","key":"10.1016\/j.bone.2022.116576_bb0700","doi-asserted-by":"crossref","first-page":"11772","DOI":"10.1074\/jbc.RA119.007660","article-title":"Deficiency in the phosphatase PHLPP1 suppresses osteoclast-mediated bone resorption and enhances bone formation in mice","volume":"294","author":"Mattson","year":"2019","journal-title":"J. Biol. Chem."},{"issue":"5","key":"10.1016\/j.bone.2022.116576_bb0705","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1002\/jbm.a.36626","article-title":"Effect of calcium phosphate phases affecting the crosstalk between osteoblasts and osteoclasts in vitro","volume":"107","author":"Shiwaku","year":"2019","journal-title":"J. Biomed. Mater. Res. A"},{"issue":"2","key":"10.1016\/j.bone.2022.116576_bb0710","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.cmet.2006.05.012","article-title":"Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis","volume":"4","author":"Zhao","year":"2006","journal-title":"Cell Metab."},{"issue":"10","key":"10.1016\/j.bone.2022.116576_bb0715","doi-asserted-by":"crossref","first-page":"4482","DOI":"10.1096\/fj.14-254300","article-title":"EphrinB2 signaling in osteoblasts promotes bone mineralization by preventing apoptosis","volume":"28","author":"Tonna","year":"2014","journal-title":"FASEB J."},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0720","doi-asserted-by":"crossref","first-page":"3436","DOI":"10.1038\/s41467-019-11373-9","article-title":"Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone","volume":"10","author":"Vrahnas","year":"2019","journal-title":"Nat. Commun."},{"issue":"10","key":"10.1016\/j.bone.2022.116576_bb0725","article-title":"Suppression of bone formation by osteoclastic expression of semaphorin 4D","volume":"23","author":"Negishi-Koga","year":"2011","journal-title":"Nat. Med."},{"issue":"11","key":"10.1016\/j.bone.2022.116576_bb0730","doi-asserted-by":"crossref","first-page":"4321","DOI":"10.1182\/blood-2004-07-2885","article-title":"Sema4D induces angiogenesis through met recruitment by plexin B1","volume":"105","author":"Conrotto","year":"2005","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0735","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S1359-6101(02)00073-4","article-title":"CD100\/Sema4D, a lymphocyte semaphorin involved in the regulation of humoral and cellular immune responses","volume":"14","author":"Suzuki","year":"2003","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.bone.2022.116576_bb0740","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1146\/annurev-physiol-021119-034425","article-title":"Osteoclasts provide coupling signals to osteoblast lineage cells through multiple mechanisms","volume":"82","author":"Sims","year":"2020","journal-title":"Annu. Rev. Physiol."},{"issue":"9","key":"10.1016\/j.bone.2022.116576_bb0745","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1091\/mbc.e12-08-0572","article-title":"Extracellular vesicles: communication, coercion, and conditioning","volume":"24","author":"Shifrin","year":"2013","journal-title":"Mol. Biol. Cell"},{"issue":"3","key":"10.1016\/j.bone.2022.116576_bb0750","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1124\/pr.112.005983","article-title":"Classification, functions, and clinical relevance of extracellular vesicles","volume":"64","author":"van der Pol","year":"2012","journal-title":"Pharmacol. Rev."},{"issue":"7722","key":"10.1016\/j.bone.2022.116576_bb0755","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1038\/s41586-018-0482-7","article-title":"Coupling of bone resorption and formation by RANKL reverse signalling","volume":"561","author":"Ikebuchi","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.bone.2022.116576_bb0760","doi-asserted-by":"crossref","first-page":"10872","DOI":"10.1038\/ncomms10872","article-title":"Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation","volume":"7","author":"Li","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bone.2022.116576_bb0765","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/j.omtn.2021.01.031","article-title":"Osteoclast-derived small extracellular vesicles induce osteogenic differentiation via inhibiting ARHGAP1","volume":"23","author":"Liang","year":"2021","journal-title":"Mol. Ther.\u2013Nucleic Acids"},{"key":"10.1016\/j.bone.2022.116576_bb0770","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.abb.2014.06.017","article-title":"The great beauty of the osteoclast","volume":"558","author":"Cappariello","year":"2014","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.bone.2022.116576_bb0775","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.bone.2019.06.023","article-title":"The osteoclast, a target cell for microorganisms","volume":"127","author":"Raynaud-Messina","year":"2019","journal-title":"Bone"},{"issue":"8","key":"10.1016\/j.bone.2022.116576_bb0780","first-page":"3046","article-title":"COVID-19 illness and treatment decrease bone mineral density of surviving hospitalized patients","volume":"26","author":"Berktas","year":"2022","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"10.1016\/j.bone.2022.116576_bb0785","doi-asserted-by":"crossref","DOI":"10.1016\/j.bone.2020.115790","article-title":"Early extrapulmonary prognostic features in chest computed tomography in COVID-19 pneumonia: bone mineral density is a relevant predictor for the clinical outcome - a multicenter feasibility study","volume":"144","author":"Kottlors","year":"2021","journal-title":"Bone"},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0790","doi-asserted-by":"crossref","first-page":"2539","DOI":"10.1038\/s41467-022-30195-w","article-title":"SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters","volume":"13","author":"Qiao","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bone.2022.116576_bb0795","doi-asserted-by":"crossref","DOI":"10.1016\/j.bone.2021.116227","article-title":"Osteoclast-mediated bone loss observed in a COVID-19 mouse model","volume":"154","author":"Awosanya","year":"2022","journal-title":"Bone"},{"issue":"2","key":"10.1016\/j.bone.2022.116576_bb0800","doi-asserted-by":"crossref","first-page":"155","DOI":"10.4103\/2231-0746.92783","article-title":"Osteopetrosis-A rare entity with osteomyelitis","volume":"1","author":"Bedi","year":"2011","journal-title":"Ann. Maxillofac. Surg."},{"issue":"1","key":"10.1016\/j.bone.2022.116576_bb0805","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1038\/s41413-022-00206-z","article-title":"Specific inflammatory osteoclast precursors induced during chronic inflammation give rise to highly active osteoclasts associated with inflammatory bone loss","volume":"10","author":"Meirow","year":"2022","journal-title":"Bone Res."},{"issue":"12","key":"10.1016\/j.bone.2022.116576_bb0810","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1038\/s41590-019-0526-7","article-title":"Identification of a novel arthritis-associated osteoclast precursor macrophage regulated by FoxM1","volume":"20","author":"Hasegawa","year":"2019","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.bone.2022.116576_bb0815","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/164_2019_346","article-title":"Cytokines and bone: osteoimmunology","volume":"262","author":"Lorenzo","year":"2020","journal-title":"Handb. Exp. Pharmacol."}],"container-title":["Bone"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328222002538?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328222002538?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T14:15:43Z","timestamp":1778940943000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S8756328222002538"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":163,"alternative-id":["S8756328222002538"],"URL":"https:\/\/doi.org\/10.1016\/j.bone.2022.116576","relation":{},"ISSN":["8756-3282"],"issn-type":[{"value":"8756-3282","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Osteoclasts: Other functions","name":"articletitle","label":"Article Title"},{"value":"Bone","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bone.2022.116576","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"116576"}}