{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T21:03:03Z","timestamp":1792011783848,"version":"4.4.0"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bone"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.bone.2024.117114","type":"journal-article","created":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T02:55:18Z","timestamp":1715050518000},"page":"117114","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Berberine ameliorates nonalcoholic fatty liver disease-induced bone loss by inhibiting ferroptosis"],"prefix":"10.1016","volume":"185","author":[{"given":"Shaobo","family":"Gu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junzhuo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyi","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunyao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deyi","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Runxiang","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengli","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengli","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zongkai","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongze","family":"Lou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyun","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunxiao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.bone.2024.117114_bb0005","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1002\/hep.31173","article-title":"Changes in the global burden of chronic liver diseases from 2012 to 2017: the growing impact of NAFLD","volume":"72","author":"Paik","year":"2020","journal-title":"Hepatology"},{"issue":"7","key":"10.1016\/j.bone.2024.117114_bb0010","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1038\/s41577-021-00639-3","article-title":"Immune cell-mediated features of non-alcoholic steatohepatitis","volume":"22","author":"Huby","year":"2022","journal-title":"Nat. Rev. Immunol."},{"issue":"1","key":"10.1016\/j.bone.2024.117114_bb0015","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1038\/s41392-022-01119-3","article-title":"Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver\/steatohepatitis (NAFL\/NASH)","volume":"7","author":"Xu","year":"2022","journal-title":"Signal Transduct. Target. Ther."},{"issue":"1","key":"10.1016\/j.bone.2024.117114_bb0020","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1002\/hep.32534","article-title":"Relationship between NAFLD and coronary artery disease: a Mendelian randomization study","volume":"77","author":"Ren","year":"2023","journal-title":"Hepatology"},{"issue":"8","key":"10.1016\/j.bone.2024.117114_bb0025","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1038\/s41574-021-00507-z","article-title":"Emerging therapeutic approaches for the treatment of NAFLD and type 2 diabetes mellitus","volume":"17","author":"Ferguson","year":"2021","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.bone.2024.117114_bb0030","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.838079","article-title":"Inflammation and cancer: from the development of personalized indicators to novel therapeutic strategies","volume":"13","author":"Ballerini","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.bone.2024.117114_bb0035","doi-asserted-by":"crossref","first-page":"583","DOI":"10.2147\/CIA.S54614","article-title":"The epidemiology and management of postmenopausal osteoporosis: a viewpoint from Brazil","volume":"10","author":"Baccaro","year":"2015","journal-title":"Clin. Interv. Aging"},{"key":"10.1016\/j.bone.2024.117114_bb0040","series-title":"Prevalence and Trends in Low Bone Density, Osteopenia and Osteoporosis in U.S. Adults With Non-Alcoholic Fatty Liver Disease, 2005\u20132014. Front Endocrinol (Lausanne)","first-page":"825448","volume":"12","author":"Zhai","year":"2021"},{"issue":"7","key":"10.1016\/j.bone.2024.117114_bb0045","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001680","article-title":"Association of non-alcoholic fatty liver disease with chronic kidney disease: a systematic review and meta-analysis","volume":"11","author":"Musso","year":"2014","journal-title":"PLoS Med."},{"key":"10.1016\/j.bone.2024.117114_bb0050","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/9067610","article-title":"Melatonin suppresses Ferroptosis induced by high glucose via activation of the Nrf2\/HO-1 signaling pathway in type 2 diabetic osteoporosis","volume":"2020","author":"Ma","year":"2020","journal-title":"Oxidative Med. Cell. Longev."},{"issue":"2","key":"10.1016\/j.bone.2024.117114_bb0055","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/s41419-020-2298-2","article-title":"Ferroptosis: past, present and future","volume":"11","author":"Li","year":"2020","journal-title":"Cell Death Dis."},{"issue":"5","key":"10.1016\/j.bone.2024.117114_bb0060","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","article-title":"Ferroptosis: an iron-dependent form of nonapoptotic cell death","volume":"149","author":"Dixon","year":"2012","journal-title":"Cell"},{"issue":"Suppl. 5","key":"10.1016\/j.bone.2024.117114_bb0065","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1093\/ndt\/11.supp5.48","article-title":"Lipoxidation products as biomarkers of oxidative damage to proteins during lipid peroxidation reactions","volume":"11","author":"Requena","year":"1996","journal-title":"Nephrol. Dial. Transplant."},{"issue":"8","key":"10.1016\/j.bone.2024.117114_bb0070","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1007\/s13238-020-00789-5","article-title":"Cystine transporter SLC7A11\/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy","volume":"12","author":"Koppula","year":"2021","journal-title":"Protein Cell"},{"issue":"3","key":"10.1016\/j.bone.2024.117114_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2017.11.048","article-title":"Selenium utilization by GPX4 is required to prevent Hydroperoxide-induced ferroptosis","volume":"172","author":"Ingold","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.bone.2024.117114_bb0080","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.canlet.2020.02.015","article-title":"Ferroptosis, a novel pharmacological mechanism of anti-cancer drugs","volume":"483","author":"Su","year":"2020","journal-title":"Cancer Lett."},{"issue":"1\u20132","key":"10.1016\/j.bone.2024.117114_bb0085","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.cell.2013.12.010","article-title":"Regulation of ferroptotic cancer cell death by GPX4","volume":"156","author":"Yang","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.bone.2024.117114_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101483","article-title":"Identification of Frataxin as a regulator of ferroptosis","volume":"32","author":"Du","year":"2020","journal-title":"Redox Biol."},{"issue":"5","key":"10.1016\/j.bone.2024.117114_bb0095","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/j.fitote.2012.04.012","article-title":"Phyto-chemical and pharmacological applications of Berberis aristata","volume":"83","author":"Potdar","year":"2012","journal-title":"Fitoterapia"},{"issue":"2","key":"10.1016\/j.bone.2024.117114_bb0100","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1080\/03602532.2017.1306544","article-title":"The metabolism of berberine and its contribution to the pharmacological effects","volume":"49","author":"Wang","year":"2017","journal-title":"Drug Metab. Rev."},{"issue":"17","key":"10.1016\/j.bone.2024.117114_bb0105","doi-asserted-by":"crossref","DOI":"10.3390\/nu14173459","article-title":"Berberine in non-alcoholic fatty liver disease-a review","volume":"14","author":"Koperska","year":"2022","journal-title":"Nutrients"},{"issue":"12","key":"10.1016\/j.bone.2024.117114_bb0110","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1038\/nm1135","article-title":"Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins","volume":"10","author":"Kong","year":"2004","journal-title":"Nat. Med."},{"issue":"1","key":"10.1016\/j.bone.2024.117114_bb0115","doi-asserted-by":"crossref","first-page":"11934","DOI":"10.1038\/s41598-019-48331-w","article-title":"Berberine improved experimental chronic colitis by regulating interferon-gamma- and IL-17A-producing lamina propria CD4(+) T cells through AMPK activation","volume":"9","author":"Takahara","year":"2019","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.bone.2024.117114_bb0120","first-page":"258","article-title":"Berberine ameliorates lipopolysaccharide-induced inflammatory responses in mouse inner medullary collecting duct-3 cells by downregulation of NF-kappaB pathway","volume":"21","author":"Kim","year":"2020","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.bone.2024.117114_bb0125","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/j.biopha.2018.04.161","article-title":"Berberine suppresses growth and metastasis of endometrial cancer cells via miR-101\/COX-2","volume":"103","author":"Wang","year":"2018","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.bone.2024.117114_bb0130","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1080\/13880209.2018.1548627","article-title":"Berberine inhibits angiogenesis in glioblastoma xenografts by targeting the VEGFR2\/ERK pathway","volume":"56","author":"Jin","year":"2018","journal-title":"Pharm. Biol."},{"issue":"7","key":"10.1016\/j.bone.2024.117114_bb0135","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.bcp.2009.11.017","article-title":"Modulation of glucagon-like peptide-1 release by berberine: in vivo and in vitro studies","volume":"79","author":"Yu","year":"2010","journal-title":"Biochem. Pharmacol."},{"issue":"3","key":"10.1016\/j.bone.2024.117114_bb0140","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1208\/s12249-010-9520-y","article-title":"Physicochemical characterization of berberine chloride: a perspective in the development of a solution dosage form for oral delivery","volume":"11","author":"Battu","year":"2010","journal-title":"AAPS PharmSciTech"},{"issue":"8","key":"10.1016\/j.bone.2024.117114_bb0145","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1517\/14712598.2012.704014","article-title":"Berberine on metabolic and cardiovascular risk factors: an analysis from preclinical evidences to clinical trials","volume":"12","author":"Derosa","year":"2012","journal-title":"Expert. Opin. Biol. Ther."},{"issue":"6","key":"10.1016\/j.bone.2024.117114_bb0150","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1536\/ihj.17-458","article-title":"Increased bioavailable Berberine protects against myocardial ischemia reperfusion injury through attenuation of NFkappaB and JNK signaling pathways","volume":"59","author":"Yu","year":"2018","journal-title":"Int. Heart J."},{"issue":"4","key":"10.1016\/j.bone.2024.117114_bb0155","doi-asserted-by":"crossref","first-page":"E812","DOI":"10.1152\/ajpendo.90710.2008","article-title":"Berberine improves lipid dysregulation in obesity by controlling central and peripheral AMPK activity","volume":"296","author":"Kim","year":"2009","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"issue":"7","key":"10.1016\/j.bone.2024.117114_bb0160","doi-asserted-by":"crossref","first-page":"2559","DOI":"10.1210\/jc.2007-2404","article-title":"Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine","volume":"93","author":"Zhang","year":"2008","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.bone.2024.117114_bb0165","article-title":"Effects of Berberine on the gastrointestinal microbiota","volume":"10","author":"Zhang","year":"2020","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.bone.2024.117114_bb0170","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.freeradbiomed.2019.06.019","article-title":"Berberine attenuates nonalcoholic hepatic steatosis through the AMPK-SREBP-1c-SCD1 pathway","volume":"141","author":"Zhu","year":"2019","journal-title":"Free Radic. Biol. Med."},{"issue":"7","key":"10.1016\/j.bone.2024.117114_bb0175","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1002\/jbmr.141","article-title":"Guidelines for assessment of bone microstructure in rodents using micro-computed tomography","volume":"25","author":"Bouxsein","year":"2010","journal-title":"J. Bone Miner. Res."},{"issue":"6937","key":"10.1016\/j.bone.2024.117114_bb0180","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/nature01658","article-title":"Osteoclast differentiation and activation","volume":"423","author":"Boyle","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.bone.2024.117114_bb0185","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.ejphar.2015.05.068","article-title":"Current knowledge and pharmacological profile of berberine: an update","volume":"761","author":"Kumar","year":"2015","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bone.2024.117114_bb0190","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.jep.2014.09.049","article-title":"Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension","volume":"161","author":"Lan","year":"2015","journal-title":"J. Ethnopharmacol."},{"issue":"5","key":"10.1016\/j.bone.2024.117114_bb0195","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1007\/s00774-021-01225-2","article-title":"Protective effects of berberine on senile osteoporosis in mice","volume":"39","author":"Chen","year":"2021","journal-title":"J. Bone Miner. Metab."},{"key":"10.1016\/j.bone.2024.117114_bb0200","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.phrs.2017.03.002","article-title":"Berberine bioisostere Q8 compound stimulates osteoblast differentiation and function in vitro","volume":"119","author":"Han","year":"2017","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.bone.2024.117114_bb0205","article-title":"Ferroptosis: a trigger of proinflammatory state progression to immunogenicity in necroinflammatory disease","volume":"12","author":"Li","year":"2021","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.bone.2024.117114_bb0210","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/s41392-020-00428-9","article-title":"Ferroptosis: mechanisms and links with diseases","volume":"6","author":"Yan","year":"2021","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.bone.2024.117114_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155342","article-title":"Poliumoside protects against type 2 diabetes-related osteoporosis by suppressing ferroptosis via activation of the Nrf2\/GPX4 pathway","volume":"125","author":"Xu","year":"2024","journal-title":"Phytomedicine"},{"key":"10.1016\/j.bone.2024.117114_bb0220","article-title":"Polyphenols synergistic drugs to ameliorate non-alcoholic fatty liver disease via signal pathway and gut microbiota: a review","author":"Li","year":"2024","journal-title":"J. Adv. Res."},{"issue":"Pt 2","key":"10.1016\/j.bone.2024.117114_bb0225","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.freeradbiomed.2022.11.013","article-title":"VDR activation attenuates osteoblastic ferroptosis and senescence by stimulating the Nrf2\/GPX4 pathway in age-related osteoporosis","volume":"193","author":"Xu","year":"2022","journal-title":"Free Radic. Biol. Med."},{"issue":"1","key":"10.1016\/j.bone.2024.117114_bb0230","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1038\/s12276-023-01125-7","article-title":"Vitamin D ameliorates age-induced nonalcoholic fatty liver disease by increasing the mitochondrial contact site and cristae organizing system (MICOS) 60 level","volume":"56","author":"Kim","year":"2024","journal-title":"Exp. Mol. Med."},{"issue":"1","key":"10.1016\/j.bone.2024.117114_bb0235","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1186\/s13046-024-03039-2","article-title":"Augmented ERO1alpha upon mTORC1 activation induces ferroptosis resistance and tumor progression via upregulation of SLC7A11","volume":"43","author":"Wang","year":"2024","journal-title":"J. Exp. Clin. Cancer Res."},{"key":"10.1016\/j.bone.2024.117114_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.jare.2024.04.009","article-title":"Tanshinone IIA destabilizes SLC7A11 by regulating PIAS4-mediated SUMOylation of SLC7A11 through KDM1A, and promotes ferroptosis in breast cancer","author":"Luo","year":"2024","journal-title":"J. Adv. Res."},{"issue":"1","key":"10.1016\/j.bone.2024.117114_bb0245","doi-asserted-by":"crossref","first-page":"2260646","DOI":"10.1080\/13510002.2023.2260646","article-title":"Slc7a11 stimulates glutathione synthesis to preserve fatty acid metabolism in primary hepatocytes","volume":"28","author":"Liu","year":"2023","journal-title":"Redox Rep."},{"key":"10.1016\/j.bone.2024.117114_bb0250","doi-asserted-by":"crossref","first-page":"1191826","DOI":"10.3389\/fimmu.2023.1191826","article-title":"The mechanism of ferroptosis in early brain injury after subarachnoid hemorrhage","volume":"14","author":"Deng","year":"2023","journal-title":"Front. Immunol."},{"issue":"2","key":"10.1016\/j.bone.2024.117114_bb0255","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s00535-023-02054-y","article-title":"Induction of ferroptosis by photodynamic therapy and enhancement of antitumor effect with ferroptosis inducers","volume":"59","author":"Kojima","year":"2023","journal-title":"J. Gastroenterol."},{"key":"10.1016\/j.bone.2024.117114_bb0260","doi-asserted-by":"crossref","first-page":"1237153","DOI":"10.3389\/fnins.2023.1237153","article-title":"Attenuation of ferroptosis as a potential therapeutic target for neuropsychiatric manifestations of post-COVID syndrome","volume":"17","author":"Sousa","year":"2023","journal-title":"Front. Neurosci."},{"issue":"6","key":"10.1016\/j.bone.2024.117114_bb0265","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202201958R","article-title":"Interaction between ferroptosis and TNF-alpha: impact in obesity-related osteoporosis","volume":"37","author":"Chen","year":"2023","journal-title":"FASEB J."},{"key":"10.1016\/j.bone.2024.117114_bb0270","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/9872243","article-title":"ATF3 regulates osteogenic function by mediating osteoblast ferroptosis in type 2 diabetic osteoporosis","volume":"2022","author":"Zhao","year":"2022","journal-title":"Dis. Markers"},{"key":"10.1016\/j.bone.2024.117114_bb0275","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.jare.2023.02.007","article-title":"Bavachinin protects the liver in NAFLD by promoting regeneration via targeting PCNA","volume":"55","author":"Dong","year":"2024","journal-title":"J. Adv. Res."},{"issue":"5","key":"10.1016\/j.bone.2024.117114_bb0280","doi-asserted-by":"crossref","first-page":"2036","DOI":"10.7150\/thno.91084","article-title":"Depletion of ApoA5 aggravates spontaneous and diet-induced nonalcoholic fatty liver disease by reducing hepatic NR1D1 in hamsters","volume":"14","author":"Guo","year":"2024","journal-title":"Theranostics"}],"container-title":["Bone"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328224001030?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328224001030?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T01:19:15Z","timestamp":1718587155000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S8756328224001030"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":56,"alternative-id":["S8756328224001030"],"URL":"https:\/\/doi.org\/10.1016\/j.bone.2024.117114","relation":{},"ISSN":["8756-3282"],"issn-type":[{"value":"8756-3282","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Berberine ameliorates nonalcoholic fatty liver disease-induced bone loss by inhibiting ferroptosis","name":"articletitle","label":"Article Title"},{"value":"Bone","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bone.2024.117114","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117114"}}