{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T14:49:42Z","timestamp":1792594182737,"version":"4.5.0"},"reference-count":19,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003593","name":"National Council for Scientific and Technological Development","doi-asserted-by":"publisher","award":["403656\/2021-4"],"award-info":[{"award-number":["403656\/2021-4"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bone"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.bone.2024.117349","type":"journal-article","created":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T09:40:19Z","timestamp":1732786819000},"page":"117349","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Morphology and spatial distribution of cortical bone canals: Evaluation of shape parameters, lacunarity, and fractal dimension in the human irradiated mandible"],"prefix":"10.1016","volume":"192","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7395-6597","authenticated-orcid":false,"given":"Karin Berria","family":"Tomazelli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3793-4240","authenticated-orcid":false,"given":"Bianca Carla","family":"Bianco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6307-9698","authenticated-orcid":false,"given":"Barbara Rech","family":"de Castro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2019-1687","authenticated-orcid":false,"given":"Isabela","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6891-8176","authenticated-orcid":false,"given":"Vith\u00f3ria Rabelo","family":"Zimmer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4492-8957","authenticated-orcid":false,"given":"Priscila Barbosa Ferreira","family":"Soares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6876-1151","authenticated-orcid":false,"given":"Liliane Janete","family":"Grando","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9511-5078","authenticated-orcid":false,"given":"Gustavo Davi","family":"Rabelo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bone.2024.117349_bb0005","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1080\/09553002.2022.2013568","article-title":"Irradiation affects the structural, cellular and molecular components of jawbones","volume":"98","author":"Padala","year":"2022","journal-title":"Int. J. Radiat. Biol."},{"key":"10.1016\/j.bone.2024.117349_bb0010","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.joms.2015.07.009","article-title":"Histopathologic and histomorphometric analysis of irradiation injury in bone and the surrounding soft tissues of the jaws","volume":"74","author":"Curi","year":"2016","journal-title":"J. Oral Maxillofac. Surg."},{"key":"10.1016\/j.bone.2024.117349_bb0015","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s13014-019-1219-y","article-title":"Ionizing radiation and bone quality: time-dependent effects","volume":"14","author":"Limirio","year":"2019","journal-title":"Radiat. Oncol."},{"key":"10.1016\/j.bone.2024.117349_bb0020","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1002\/jemt.20826","article-title":"Histological analysis of the alterations on cortical bone channels network after radiotherapy: a rabbit study","volume":"73","author":"Rabelo","year":"2010","journal-title":"Microsc. Res. Tech."},{"key":"10.1016\/j.bone.2024.117349_bb0025","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1590\/0103-6440202103384","article-title":"Cortical bone modifications after radiotherapy: cortex porosity and osteonal changes evaluated over time","volume":"32","author":"Borges","year":"2021","journal-title":"Braz. Dent. J."},{"key":"10.1016\/j.bone.2024.117349_bb0030","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/BF00125351","article-title":"Lacunarity indices as measures of landscape texture","volume":"8","author":"Plotnick","year":"1993","journal-title":"Landsc. Ecol."},{"key":"10.1016\/j.bone.2024.117349_bb0035","first-page":"20","article-title":"Lacunarity for spatial heterogeneity measurement in GIS, Geographic","volume":"6","author":"Dong","year":"2000","journal-title":"Inf. Sci."},{"key":"10.1016\/j.bone.2024.117349_bb0040","doi-asserted-by":"crossref","DOI":"10.1259\/dmfr.20180457","article-title":"Use of fractal analysis in dental images: a systematic review","volume":"49","author":"Kato","year":"2020","journal-title":"Dentomaxillofac. Radiol."},{"key":"10.1016\/j.bone.2024.117349_bb0045","doi-asserted-by":"crossref","first-page":"153","DOI":"10.5624\/isd.20230042","article-title":"Fractal dimension, lacunarity, and cortical thickness in the mandible: analyzing differences between healthy men and women with cone-beam computed tomography","volume":"53","author":"Santos","year":"2023","journal-title":"Imaging Science in Dentistry."},{"issue":"1","key":"10.1016\/j.bone.2024.117349_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.jocd.2024.101531","article-title":"Fractal analysis of mandible in panoramic radiographs of patients received radiotherapy for nasopharyngeal carcinoma","volume":"28","author":"Tepe","year":"2024","journal-title":"J. Clin. Densitom."},{"issue":"3","key":"10.1016\/j.bone.2024.117349_bb0055","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1590\/0103-6440201801979","article-title":"Use of micro-computed tomography for bone evaluation in dentistry","volume":"29","author":"Irie","year":"2018","journal-title":"Braz. Dent. J."},{"key":"10.1016\/j.bone.2024.117349_bb0060","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1007\/s00784-017-2153-8","article-title":"Evaluation of cortical mandibular bone in patients with oral squamous cell carcinoma","volume":"22","author":"Rabelo","year":"2018","journal-title":"Clin. Oral Investig."},{"key":"10.1016\/j.bone.2024.117349_bb0065","author":"Karperien"},{"key":"10.1016\/j.bone.2024.117349_bb0070","doi-asserted-by":"crossref","unstructured":"D.B. Burr, O. Akkus, Chapter 1 - bone morphology and organization, Editor(s): D.B. Burr, M.R. Allen, Basic and Applied Bone Biology, Academic Press, 2014, pp. 3\u201325, ISBN 9780124160156, doi:https:\/\/doi.org\/10.1016\/B978-0-12-416015-6.00001-0.","DOI":"10.1016\/B978-0-12-416015-6.00001-0"},{"key":"10.1016\/j.bone.2024.117349_bb0075","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1111\/jre.12416","article-title":"Implant osseointegration in irradiated bone: an experimental study","volume":"52","author":"Oca\u00f1a","year":"2017","journal-title":"J. Periodontal Res."},{"issue":"6","key":"10.1016\/j.bone.2024.117349_bb0080","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1080\/03008207.2018.1439482","article-title":"Therapeutic ionizing radiation induced bone loss: a review of in vivo and in vitro findings","volume":"59","author":"Zhang","year":"2018","journal-title":"Connect. Tissue Res."},{"key":"10.1016\/j.bone.2024.117349_bb0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00774-007-0793-5","article-title":"Bone quality: the material and structural basis of bone strength","volume":"26","author":"Seeman","year":"2008","journal-title":"J. Bone Miner. Metab."},{"key":"10.1016\/j.bone.2024.117349_bb0090","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1080\/01913123.2023.2295458","article-title":"Microstructural changes in the irradiated and osteoradionecrotic bone: a SEM study","volume":"48","author":"Reddy","year":"2024","journal-title":"Ultrastruct. Pathol."},{"key":"10.1016\/j.bone.2024.117349_bb0095","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1119\/1.13295","article-title":"The Fractal Geometry of Nature","volume":"51","author":"Mandelbrot","year":"1983","journal-title":"Am. J. Phys."}],"container-title":["Bone"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328224003387?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328224003387?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T22:08:02Z","timestamp":1737756482000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S8756328224003387"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":19,"alternative-id":["S8756328224003387"],"URL":"https:\/\/doi.org\/10.1016\/j.bone.2024.117349","relation":{},"ISSN":["8756-3282"],"issn-type":[{"value":"8756-3282","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Morphology and spatial distribution of cortical bone canals: Evaluation of shape parameters, lacunarity, and fractal dimension in the human irradiated mandible","name":"articletitle","label":"Article Title"},{"value":"Bone","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bone.2024.117349","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117349"}}