{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T22:33:56Z","timestamp":1793572436488,"version":"4.5.0"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T00:00:00Z","timestamp":1750204800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004092","name":"Kuopion Yliopistollinen Sairaala","doi-asserted-by":"publisher","award":["5203101"],"award-info":[{"award-number":["5203101"]}],"id":[{"id":"10.13039\/501100004092","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002341","name":"Research Council of Finland","doi-asserted-by":"publisher","award":["2021\/338647"],"award-info":[{"award-number":["2021\/338647"]}],"id":[{"id":"10.13039\/501100002341","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002341","name":"Research Council of Finland","doi-asserted-by":"publisher","award":["2023\/356743"],"award-info":[{"award-number":["2023\/356743"]}],"id":[{"id":"10.13039\/501100002341","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bone"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.bone.2025.117564","type":"journal-article","created":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T02:53:20Z","timestamp":1750128800000},"page":"117564","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Relation of lateral lumbar spine DXA to age-related bone loss, aortic calcification, scoliosis and vertebral degeneration: Analysis of over 10,000 patients"],"prefix":"10.1016","volume":"199","author":[{"given":"Nina E.","family":"H\u00e4nninen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antti","family":"Voss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suvi","family":"Hartikainen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomi","family":"Nissinen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pentti","family":"Rautio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reijo","family":"Sund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sami P.","family":"V\u00e4\u00e4n\u00e4nen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bone.2025.117564_bb0005","doi-asserted-by":"crossref","DOI":"10.1007\/s11657-020-00871-9","article-title":"SCOPE 2021: a new scorecard for osteoporosis in Europe","volume":"16","author":"Kanis","year":"2021","journal-title":"Arch. Osteoporos."},{"key":"10.1016\/j.bone.2025.117564_bb0010","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1172\/JCI110667","article-title":"Changes in bone mineral density of the proximal femur and spine with aging: differences between the postmenopausal and senile osteoporosis syndromes","volume":"70","author":"Riggs","year":"1982","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bone.2025.117564_bb0015","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1007\/s00774-011-0305-5","article-title":"Body mass index and bone loss among postmenopausal women: the 10-year follow-up of the OSTPRE cohort","volume":"30","author":"Saarelainen","year":"2012","journal-title":"J. Bone Miner. Metab."},{"key":"10.1016\/j.bone.2025.117564_bb0020","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/jbmr.4444","article-title":"Characteristics of long-term femoral neck bone loss in postmenopausal women: a 25-year follow-up","volume":"37","author":"Moilanen","year":"2022","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2025.117564_bb0025","author":"International Society for Clinical Densitometry (ISCD)"},{"key":"10.1016\/j.bone.2025.117564_bb0030","series-title":"Prevention and Management of Osteoporosis: Report of A WHO Scientific Group","author":"WHO Study Group","year":"2003"},{"key":"10.1016\/j.bone.2025.117564_bb0035","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1007\/s00198-004-1780-5","article-title":"Assessment of fracture risk","volume":"16","author":"Kanis","year":"2005","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2025.117564_bb0040","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/0140-6736(93)92555-8","article-title":"Bone density at various sites for prediction of hip fractures","volume":"341","author":"Cummings","year":"1993","journal-title":"Lancet"},{"key":"10.1016\/j.bone.2025.117564_bb0045","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1002\/jbmr.3194","article-title":"The ability of a single BMD and fracture history assessment to predict fracture over 25 years in postmenopausal women: the study of osteoporotic fractures","volume":"33","author":"Black","year":"2018","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2025.117564_bb0050","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1007\/s00198-003-1463-7","article-title":"The risk and burden of vertebral fractures in Sweden","volume":"15","author":"Kanis","year":"2004","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2025.117564_bb0055","first-page":"2015","article-title":"Different approaches to bone densitometry","volume":"41","author":"Fogelman","year":"2000","journal-title":"The J. Nucl. Med."},{"key":"10.1016\/j.bone.2025.117564_bb0060","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1002\/jbmr.5650050515","article-title":"Lateral dual-photon absorptiometry: a new technique to measure the bone mineral density at the lumbar spine","volume":"5","author":"Uebelhart","year":"1990","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2025.117564_bb0065","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1210\/jcem-70-4-1202","article-title":"The impact of osteophytic and vascular calcifications on vertebral mineral density measurements in men","volume":"70","author":"Orwoll","year":"1990","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.bone.2025.117564_bb0070","doi-asserted-by":"crossref","first-page":"119","DOI":"10.2215\/CJN.03410708","article-title":"Determination and validation of aortic calcification measurement from lateral bone densitometry in Dialysis patients","volume":"4","author":"Toussaint","year":"2009","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"10.1016\/j.bone.2025.117564_bb0075","doi-asserted-by":"crossref","DOI":"10.1007\/s11657-013-0136-1","article-title":"Osteoporosis in the European Union: medical management, epidemiology and economic burden: a report prepared in collaboration with the international osteoporosis foundation (IOF) and the European Federation of Pharmaceutical Industry Associations (EFPIA)","volume":"8","author":"Hernlund","year":"2013","journal-title":"Arch Osteoporos"},{"key":"10.1016\/j.bone.2025.117564_bb0080","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1053\/j.semnuclmed.2010.12.002","article-title":"Bone densitometry","volume":"41","author":"Chun","year":"2011","journal-title":"Semin. Nucl. Med."},{"key":"10.1016\/j.bone.2025.117564_bb0085","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/s00223-012-9643-0","article-title":"Diagnostic performance of vertebral fracture assessment by the lunar iDXA scanner compared to conventional radiography","volume":"91","author":"Diacinti","year":"2012","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.bone.2025.117564_bb0090","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1007\/s00198-015-3395-4","article-title":"Accuracy of densitometric vertebral fracture assessment when performed by DXA technicians\u2014a cross-sectional, multiobserver study","volume":"27","author":"Rud","year":"2016","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2025.117564_bb0095","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.bone.2017.01.025","article-title":"Abdominal aortic calcification on dual-energy X-ray absorptiometry: methods of assessment and clinical significance","volume":"104","author":"Schousboe","year":"2017","journal-title":"Bone"},{"key":"10.1016\/j.bone.2025.117564_bb0100","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.jocd.2006.05.007","article-title":"Detection of abdominal aortic calcification with lateral spine imaging using DXA","volume":"9","author":"Schousboe","year":"2006","journal-title":"J. Clin. Densitom."},{"issue":"Suppl. 1","key":"10.1016\/j.bone.2025.117564_bb0105","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/BF02375932","article-title":"Lateral scanning of the lumbar spine: bone mineral density determination with dual energy X-ray absorptiometry","volume":"9","author":"Fukunaga","year":"1991","journal-title":"J. Bone Miner. Metab."},{"key":"10.1016\/j.bone.2025.117564_bb0110","article-title":"A comparison of lateral versus anterior-posterior spine dual energy X-ray absorptiometry for the diagnosis of osteopenia","volume":"78","author":"Finkelstein","year":"1994","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.bone.2025.117564_bb0115","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1359\/jbmr.2000.15.7.1417","article-title":"Posterior-anterior and lateral dual-energy X-ray absorptiometry for the assessment of vertebral osteoporosis and bone loss among older men","volume":"15","author":"Zmuda","year":"2000","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2025.117564_bb0120","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1007\/BF01626604","article-title":"Spinal bone mineral assessment in postmenopausal women: a comparison between dual X-ray absorptiometry and quantitative computed tomography","volume":"5","author":"Yu","year":"1995","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2025.117564_bb0125","doi-asserted-by":"crossref","first-page":"959","DOI":"10.3928\/0147-7447-20011001-15","article-title":"Evaluation of lumbar spine bone mineral density in anteroposterior lateral projections by dual-energy X-ray absorptiometry","volume":"24","author":"Sapkas","year":"2001","journal-title":"Orthopedics"},{"key":"10.1016\/j.bone.2025.117564_bb0130","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1259\/0007-1285-67-794-157","article-title":"An investigation of spinal bone mineral density measured laterally: a normal range for UK women","volume":"67","author":"Lilley","year":"1994","journal-title":"Br. J. Radiol."},{"key":"10.1016\/j.bone.2025.117564_bb0135","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/BF00298610","article-title":"Age changes of spine density in posterior-anterior projections in normal women","volume":"56","author":"Mazess","year":"1995","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.bone.2025.117564_bb0140","series-title":"X-ray Bone Densitometer with enCORE v17 Software - User Manual","author":"GE Healthcare","year":"2023"},{"key":"10.1016\/j.bone.2025.117564_bb0145","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0021-9150(97)00106-8","article-title":"New indices to classify location, severity and progression of calcific lesions in the abdominal aorta: a 25-year follow-up study","volume":"132","author":"Kauppila","year":"1997","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.bone.2025.117564_bb0150","article-title":"Deep learning ensemble for abdominal aortic calcification scoring from lumbar spine X-ray and DXA images","author":"Voss","year":"2025","journal-title":"MedRxiv"},{"key":"10.1016\/j.bone.2025.117564_bb0155","article-title":"Detecting pathological features and predicting fracture risk from dual-energy X-ray absorptiometry images using deep learning","volume":"14","author":"Nissinen","year":"2021","journal-title":"Bone Rep"},{"key":"10.1016\/j.bone.2025.117564_bb0160","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1002\/jbmr.5650071014","article-title":"Lateral spine densitometry is a more sensitive indicator of glucocorticoid-induced bone loss","volume":"7","author":"Reid","year":"1992","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2025.117564_bb0165","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s002239900510","article-title":"Lateral spine densitometry in obese women","volume":"63","author":"Brooks","year":"1998","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.bone.2025.117564_bb0170","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1007\/s001980070080","article-title":"Cross-sectional versus longitudinal evaluation of bone loss in men and women","volume":"11","author":"Melton","year":"2000","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2025.117564_bb0175","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s001980200001","article-title":"Changes in bone mineral density with age in men and women: a longitudinal study","volume":"13","author":"Warming","year":"2002","journal-title":"Osteoporos. Int."},{"issue":"Suppl. 3","key":"10.1016\/j.bone.2025.117564_bb0180","doi-asserted-by":"crossref","first-page":"S43","DOI":"10.1007\/s00198-002-1348-1","article-title":"Assessment of prevalent and incident vertebral fractures in osteoporosis research","volume":"14","author":"Genant","year":"2003","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2025.117564_bb0185","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2023.104676","article-title":"Machine learning for abdominal aortic calcification assessment from bone density machine-derived lateral spine images","volume":"94","author":"Sharif","year":"2023","journal-title":"EBioMedicine"},{"key":"10.1016\/j.bone.2025.117564_bb0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.bone.2021.115943","article-title":"Machine learning for automated abdominal aortic calcification scoring of DXA vertebral fracture assessment images: a pilot study","volume":"148","author":"Reid","year":"2021","journal-title":"Bone"},{"key":"10.1016\/j.bone.2025.117564_bb0195","series-title":"Medical Imaging 2019: Computer-Aided Diagnosis, Progress in Biomedical Optics and Imaging - Proceedings of SPIE","article-title":"Automated scoring of aortic calcification in vertebral fracture assessment images","author":"Chaplin","year":"2019"},{"key":"10.1016\/j.bone.2025.117564_bb0200","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.molmed.2009.07.001","article-title":"Vascular calcification and bone disease: the calcification paradox","volume":"15","author":"Persy","year":"2009","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.bone.2025.117564_bb0205","doi-asserted-by":"crossref","first-page":"e131","DOI":"10.5114\/pjr.2019.84060","article-title":"Evaluation of vertebral bone mineral density in scoliosis by using quantitative computed tomography","volume":"84","author":"Sarioglu","year":"2019","journal-title":"Pol. J. Radiol."},{"key":"10.1016\/j.bone.2025.117564_bb0210","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/BF00334484","article-title":"Reproducibility of lateral spine scans using dual energy X-ray absorptiometry","volume":"51","author":"Larnach","year":"1992","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.bone.2025.117564_bb0215","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/jbmr.5650070114","article-title":"Lateral dual-energy radiography: artifact error from rib and pelvic bone","volume":"7","author":"Rupich","year":"1992","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2025.117564_bb0220","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s001980050008","article-title":"Long-term precision of DXA scanning assessed over seven years in forty postmenopausal women","volume":"11","author":"Patel","year":"2000","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2025.117564_bb0225","doi-asserted-by":"crossref","first-page":"2707","DOI":"10.1007\/s00330-010-1845-0","article-title":"Radiation exposure in X-ray-based imaging techniques used in osteoporosis","volume":"20","author":"Damilakis","year":"2010","journal-title":"Eur. Radiol."}],"container-title":["Bone"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328225001760?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328225001760?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T14:16:39Z","timestamp":1778940999000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S8756328225001760"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":45,"alternative-id":["S8756328225001760"],"URL":"https:\/\/doi.org\/10.1016\/j.bone.2025.117564","relation":{},"ISSN":["8756-3282"],"issn-type":[{"value":"8756-3282","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Relation of lateral lumbar spine DXA to age-related bone loss, aortic calcification, scoliosis and vertebral degeneration: Analysis of over 10,000 patients","name":"articletitle","label":"Article Title"},{"value":"Bone","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bone.2025.117564","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"117564"}}