{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T22:06:18Z","timestamp":1791324378105,"version":"4.3.1"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007710","name":"University of Connecticut","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01AR072052"],"award-info":[{"award-number":["R01AR072052"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bone"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.bone.2026.117829","type":"journal-article","created":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T08:19:28Z","timestamp":1770625168000},"page":"117829","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["The role of muscle fascia in heterotopic ossification and maintenance of skeletal muscle integrity in fibrodysplasia ossificans progressiva"],"prefix":"10.1016","volume":"207","author":[{"given":"L. Russell","family":"Hanson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine L.","family":"Scalise","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rayna M.","family":"Esch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liv","family":"Nevo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Goldhamer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bone.2026.117829_bb0005","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1080\/16501970510027628","article-title":"Heterotopic ossification: a review","volume":"37","author":"Bossche","year":"2005","journal-title":"J. Rehabil. Med."},{"key":"10.1016\/j.bone.2026.117829_bb0010","doi-asserted-by":"crossref","first-page":"686","DOI":"10.2106\/JBJS.I.00705","article-title":"Early mortality and cardiorespiratory failure in patients with fibrodysplasia ossificans progressiva","volume":"92","author":"Kaplan","year":"2010","journal-title":"J. Bone Jt. Surg. Am."},{"key":"10.1016\/j.bone.2026.117829_bb0015","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1002\/jbmr.2728","article-title":"The natural history of flare-ups in fibrodysplasia ossificans progressiva (FOP): a comprehensive global assessment","volume":"31","author":"Pignolo","year":"2016","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2026.117829_bb0020","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/ng1783","article-title":"A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva","volume":"38","author":"Shore","year":"2006","journal-title":"Nat. Genet."},{"key":"10.1016\/j.bone.2026.117829_bb0025","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1002\/humu.20868","article-title":"Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1","volume":"30","author":"Kaplan","year":"2009","journal-title":"Hum. Mutat."},{"key":"10.1016\/j.bone.2026.117829_bb0030","doi-asserted-by":"crossref","first-page":"2422","DOI":"10.1016\/j.gim.2022.08.013","article-title":"The natural history of fibrodysplasia ossificans progressiva: a prospective, global 36-month study","volume":"24","author":"Pignolo","year":"2022","journal-title":"Genet. Med."},{"key":"10.1016\/j.bone.2026.117829_bb0035","doi-asserted-by":"crossref","first-page":"15438","DOI":"10.1073\/pnas.1510540112","article-title":"Neofunction of ACVR1 in fibrodysplasia ossificans progressiva","volume":"112","author":"Hino","year":"2015","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bone.2026.117829_bb0040","doi-asserted-by":"crossref","first-page":"303ra137","DOI":"10.1126\/scitranslmed.aac4358","article-title":"ACVR1R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A","volume":"7","author":"Hatsell","year":"2015","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.bone.2026.117829_bb0045","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.bone.2017.11.014","article-title":"Activin A amplifies dysregulated BMP signaling and induces chondro-osseous differentiation of primary connective tissue progenitor cells in patients with fibrodysplasia ossificans progressiva (FOP)","volume":"109","author":"Wang","year":"2017","journal-title":"Bone"},{"key":"10.1016\/j.bone.2026.117829_bb0050","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1038\/s41467-018-02872-2","article-title":"Activin-dependent signaling in fibro\/adipogenic progenitors causes fibrodysplasia ossificans progressiva","volume":"9","author":"Lees-Shepard","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bone.2026.117829_bb0055","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1186\/1750-1172-6-80","article-title":"Fibrodysplasia ossificans progressiva: clinical and genetic aspects","volume":"6","author":"Pignolo","year":"2011","journal-title":"Orphanet J. Rare Dis."},{"key":"10.1016\/j.bone.2026.117829_bb0060","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-25610-7","article-title":"Diminished muscle integrity in patients with fibrodysplasia ossificans progressiva assessed with at-home electrical impedance myography","volume":"12","author":"Farid","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bone.2026.117829_bb0065","doi-asserted-by":"crossref","DOI":"10.1172\/JCI153795","article-title":"An anti-ACVR1 antibody exacerbates heterotopic ossification by fibro-adipogenic progenitors in fibrodysplasia ossificans progressiva mice","volume":"132","author":"Lees-Shepard","year":"2022","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bone.2026.117829_bb0070","doi-asserted-by":"crossref","first-page":"305","DOI":"10.7554\/eLife.40814","article-title":"Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity","volume":"7","author":"Lees-Shepard","year":"2018","journal-title":"eLife"},{"key":"10.1016\/j.bone.2026.117829_bb0075","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1002\/jbmr.4617","article-title":"Overexpression of wild-type ACVR1 in fibrodysplasia ossificans progressiva mice rescues perinatal lethality and inhibits heterotopic ossification","volume":"37","author":"Yamamoto","year":"2022","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2026.117829_bb0080","doi-asserted-by":"crossref","first-page":"177","DOI":"10.3390\/biom14020177","article-title":"Sex as a critical variable in basic and pre-clinical studies of fibrodysplasia ossificans progressiva","volume":"14","author":"Burdick","year":"2024","journal-title":"Biomolecules"},{"key":"10.1016\/j.bone.2026.117829_bb0085","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.scr.2016.06.007","article-title":"Pharmacological blockage of fibro\/adipogenic progenitor expansion and suppression of regenerative fibrogenesis is associated with impaired skeletal muscle regeneration","volume":"17","author":"Fiore","year":"2016","journal-title":"Stem Cell Res."},{"key":"10.1016\/j.bone.2026.117829_bb0090","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/ncb2015","article-title":"Muscle injury activates resident fibro\/adipogenic progenitors that facilitate myogenesis","volume":"12","author":"Joe","year":"2010","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.bone.2026.117829_bb0095","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/ncb2014","article-title":"Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle","volume":"12","author":"Uezumi","year":"2010","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.bone.2026.117829_bb0100","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1038\/nm.3869","article-title":"Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro\/adipogenic progenitors","volume":"21","author":"Lemos","year":"2015","journal-title":"Nat. Med."},{"key":"10.1016\/j.bone.2026.117829_bb0105","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.cell.2013.02.053","article-title":"Type 2 innate signals stimulate fibro\/adipogenic progenitors to facilitate muscle regeneration","volume":"153","author":"Heredia","year":"2013","journal-title":"Cell"},{"key":"10.1016\/j.bone.2026.117829_bb0110","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1038\/s41536-021-00201-8","article-title":"Dynamics of skeletal muscle-resident stem cells during myogenesis in fibrodysplasia ossificans progressiva","volume":"7","author":"Stanley","year":"2022","journal-title":"Npj Regen. Med."},{"key":"10.1016\/j.bone.2026.117829_bb0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1469-7580.2008.01011.x","article-title":"The fascia of the limbs and back \u2013 a review","volume":"214","author":"Benjamin","year":"2009","journal-title":"J. Anat."},{"key":"10.1016\/j.bone.2026.117829_bb0120","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2020.00253","article-title":"Skeletal muscle extracellular matrix \u2013 what do we know about its composition, regulation, and physiological roles? A narrative review","volume":"11","author":"Csapo","year":"2020","journal-title":"Front. Physiol."},{"key":"10.1016\/j.bone.2026.117829_bb0125","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aaf1090","article-title":"Two tissue-resident progenitor lineages drive distinct phenotypes of heterotopic ossification","volume":"8","author":"Dey","year":"2016","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.bone.2026.117829_bb0130","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1006\/dbio.2000.0106","article-title":"Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo","volume":"230","author":"Kisanuki","year":"2001","journal-title":"Dev. Biol."},{"key":"10.1016\/j.bone.2026.117829_bb0135","doi-asserted-by":"crossref","DOI":"10.1242\/dev.163014","article-title":"Niche-mediated BMP\/SMAD signaling regulates lung alveolar stem cell proliferation and differentiation","volume":"145","author":"Chung","year":"2018","journal-title":"Development"},{"key":"10.1016\/j.bone.2026.117829_bb0140","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1006\/bbrc.1997.7111","article-title":"A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission","volume":"237","author":"Sakai","year":"1997","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bone.2026.117829_bb0145","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1002\/gene.20104","article-title":"MyoD-Cre transgenic mice: a model for conditional mutagenesis and lineage tracing of skeletal muscle","volume":"41","author":"Chen","year":"2005","journal-title":"Genesis (New York, N.Y.: 2000)"},{"key":"10.1016\/j.bone.2026.117829_bb0150","doi-asserted-by":"crossref","first-page":"3625","DOI":"10.1242\/dev.064162","article-title":"Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration","volume":"138","author":"Murphy","year":"2011","journal-title":"Development"},{"key":"10.1016\/j.bone.2026.117829_bb0155","doi-asserted-by":"crossref","first-page":"4013","DOI":"10.1128\/MCB.23.11.4013-4025.2003","article-title":"Evolutionary divergence of platelet-derived growth factor alpha receptor signaling mechanisms","volume":"23","author":"Hamilton","year":"2003","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bone.2026.117829_bb0160","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1002\/dvg.20474","article-title":"A multifunctional reporter mouse line for Cre- and FLP-dependent lineage analysis","volume":"47","author":"Yamamoto","year":"2009","journal-title":"Genesis (New York, N.Y.: 2000)"},{"key":"10.1016\/j.bone.2026.117829_bb0165","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1002\/gene.10015","article-title":"Removal of the floxed Neo gene from a conditional knockout allele by the adenoviral Cre recombinase in vivo","volume":"31","author":"Kaartinen","year":"2001","journal-title":"Genesis (New York, N.Y.: 2000)"},{"key":"10.1016\/j.bone.2026.117829_bb0170","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1038\/nature02876","article-title":"Mrf4 determines skeletal muscle identity in Myf5:Myod double-mutant mice","volume":"431","author":"Kassar-Duchossoy","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.bone.2026.117829_bb0175","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1016\/j.stemcr.2018.01.027","article-title":"Loss of MyoD and Myf5 in skeletal muscle stem cells results in altered myogenic programming and failed regeneration","volume":"10","author":"Yamamoto","year":"2018","journal-title":"Stem Cell Rep."},{"key":"10.1016\/j.bone.2026.117829_bb0180","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/0092-8674(92)90508-A","article-title":"Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development","volume":"71","author":"Rudnicki","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.bone.2026.117829_bb0185","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-74031-x","article-title":"A novel RGB-trichrome staining method for routine histological analysis of musculoskeletal tissues","volume":"10","author":"Gaytan","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bone.2026.117829_bb0190","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/nmeth.2019","article-title":"Fiji: an open-source platform for biological-image analysis","volume":"9","author":"Schindelin","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.bone.2026.117829_bb0195","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1038\/s41592-020-01018-x","article-title":"Cellpose: a generalist algorithm for cellular segmentation","volume":"18","author":"Stringer","year":"2021","journal-title":"Nat. Methods"},{"key":"10.1016\/j.bone.2026.117829_bb0200","first-page":"br4","article-title":"Samples in many cell-based experiments are matched\/paired but taking this into account does not always increase power of statistical tests for differences in means","volume":"35","author":"Zweifach","year":"2023","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.bone.2026.117829_bb0205","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1002\/jbmr.1562","article-title":"Multipotent progenitors resident in the skeletal muscle interstitium exhibit robust BMP-dependent osteogenic activity and mediate heterotopic ossification","volume":"27","author":"Wosczyna","year":"2012","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2026.117829_bb0210","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.bone.2018.01.029","article-title":"Stem cells and heterotopic ossification: lessons from animal models","volume":"109","author":"Lees-Shepard","year":"2018","journal-title":"Bone"},{"key":"10.1016\/j.bone.2026.117829_bb0215","doi-asserted-by":"crossref","DOI":"10.1002\/jbmr.4020","article-title":"Murine tissue-resident PDGFR\u03b1+ fibro-adipogenic progenitors spontaneously acquire osteogenic phenotype in an altered inflammatory environment","author":"Eisner","year":"2020","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bone.2026.117829_bb0220","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0147198","article-title":"Comparative study of injury models for studying muscle regeneration in mice","volume":"11","author":"Hardy","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.bone.2026.117829_bb0225","series-title":"Skeletal Muscle Regeneration in the Mouse","first-page":"255","article-title":"FACS fractionation and differentiation of skeletal-muscle resident multipotent Tie2+ progenitors","author":"Biswas","year":"2016"},{"key":"10.1016\/j.bone.2026.117829_bb0230","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1016\/j.celrep.2019.04.074","article-title":"Mesenchymal stromal cells are required for regeneration and homeostatic maintenance of skeletal muscle","volume":"27","author":"Wosczyna","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.bone.2026.117829_bb0235","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1038\/8792","article-title":"Sox9 is required for cartilage formation","volume":"22","author":"Bi","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1016\/j.bone.2026.117829_bb0240","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1152\/jappl.2001.91.2.534","article-title":"Myogenic satellite cells: physiology to molecular biology","volume":"91","author":"Hawke","year":"2001","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.bone.2026.117829_bb0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2022.101682","article-title":"Bidirectional roles of skeletal muscle fibro-adipogenic progenitors in homeostasis and disease","volume":"80","author":"Chen","year":"2022","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.bone.2026.117829_bb0250","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1242\/dmm.018424","article-title":"Animal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapy","volume":"8","author":"McGreevy","year":"2015","journal-title":"Dis. Model. Mech."},{"key":"10.1016\/j.bone.2026.117829_bb0255","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/2044-5040-1-21","article-title":"Aberrant repair and fibrosis development in skeletal muscle","volume":"1","author":"Mann","year":"2011","journal-title":"Skelet. Muscle"},{"key":"10.1016\/j.bone.2026.117829_bb0260","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.ydbio.2007.08.059","article-title":"A role for the myogenic determination gene Myf5 in adult regenerative myogenesis","volume":"312","author":"Gayraud-Morel","year":"2007","journal-title":"Dev. Biol."},{"key":"10.1016\/j.bone.2026.117829_bb0265","doi-asserted-by":"crossref","first-page":"R331","DOI":"10.1152\/ajpregu.00427.2011","article-title":"Increased fat deposition in injured skeletal muscle is regulated by sex-specific hormones","volume":"302","author":"McHale","year":"2012","journal-title":"Am. J. Physiol. Regul., Integr. Comp. Physiol."},{"key":"10.1016\/j.bone.2026.117829_bb0270","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.cell.2017.06.035","article-title":"Ciliary hedgehog signaling restricts injury-induced adipogenesis","volume":"170","author":"Kopinke","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.bone.2026.117829_bb0275","doi-asserted-by":"crossref","first-page":"3766","DOI":"10.1038\/s41467-023-39506-1","article-title":"Hedgehog signaling via its ligand DHH acts as cell fate determinant during skeletal muscle regeneration","volume":"14","author":"Norris","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bone.2026.117829_bb0280","doi-asserted-by":"crossref","first-page":"611","DOI":"10.3390\/biomedicines8120611","article-title":"Genetic and acquired heterotopic ossification: a translational tale of mice and men","volume":"8","author":"Cappato","year":"2020","journal-title":"Biomedicines"},{"key":"10.1016\/j.bone.2026.117829_bb0285","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.jbmt.2016.11.003","article-title":"Defining the fascial system","volume":"21","author":"Adstrum","year":"2017","journal-title":"J. Bodyw. Mov. Ther."},{"key":"10.1016\/j.bone.2026.117829_bb0290","doi-asserted-by":"crossref","first-page":"135","DOI":"10.4103\/0970-0358.73424","article-title":"Detail microscopic analysis of deep fascia of lower limb and its surgical implication","volume":"43","author":"Bhattacharya","year":"2010","journal-title":"Indian J. Plast. Surg."},{"key":"10.1016\/j.bone.2026.117829_bb0295","article-title":"Furnishing wound repair by the subcutaneous fascia","volume":"22","author":"D","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bone.2026.117829_bb0300","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-17852-2","article-title":"Matrix stiffness and architecture drive fibro-adipogenic progenitors\u2019 activation into myofibroblasts","volume":"12","author":"Loomis","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bone.2026.117829_bb0305","doi-asserted-by":"crossref","first-page":"592","DOI":"10.3389\/fphys.2020.00592","article-title":"Structural and functional changes in the coupling of fascial tissue, skeletal muscle, and nerves during aging","volume":"11","author":"Zullo","year":"2020","journal-title":"Front. Physiol."},{"key":"10.1016\/j.bone.2026.117829_bb0310","doi-asserted-by":"crossref","DOI":"10.1016\/j.mam.2024.101277","article-title":"Fibro-adipogenic progenitors in physiological adipogenesis and intermuscular adipose tissue remodeling","volume":"97","author":"Flores-Opazo","year":"2024","journal-title":"Mol. Asp. Med."},{"key":"10.1016\/j.bone.2026.117829_bb0315","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s13395-021-00265-6","article-title":"Origins, potency, and heterogeneity of skeletal muscle fibro-adipogenic progenitors\u2014time for new definitions","volume":"11","author":"Contreras","year":"2021","journal-title":"Skelet. Muscle"}],"container-title":["Bone"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328226000554?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328226000554?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T19:25:05Z","timestamp":1776885905000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S8756328226000554"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":63,"alternative-id":["S8756328226000554"],"URL":"https:\/\/doi.org\/10.1016\/j.bone.2026.117829","relation":{},"ISSN":["8756-3282"],"issn-type":[{"value":"8756-3282","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The role of muscle fascia in heterotopic ossification and maintenance of skeletal muscle integrity in fibrodysplasia ossificans progressiva","name":"articletitle","label":"Article Title"},{"value":"Bone","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bone.2026.117829","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"117829"}}