{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T16:05:08Z","timestamp":1784649908214,"version":"3.55.0"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bone"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.bone.2026.117930","type":"journal-article","created":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T06:52:08Z","timestamp":1778482328000},"page":"117930","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Radiofrequency echographic multispectrometry assessment of osteoporosis in severe motor and intellectual disabilities: A cross-sectional study"],"prefix":"10.1016","volume":"210","author":[{"given":"Tomoko","family":"Sakai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanobu","family":"Hirao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasue","family":"Mizushima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Takashina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanae","family":"Matsuoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsutomu","family":"Oishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bone.2026.117930_bb0005","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1111\/jir.12581","article-title":"Vitamin D, bone mineral density and risk of fracture in people with intellectual disabilities","volume":"63","author":"Frighi","year":"2018","journal-title":"J. Intellect. Disabil. Res."},{"key":"10.1016\/j.bone.2026.117930_bb0010","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.braindev.2019.12.010","article-title":"Osteoporosis pathology in people with severe motor and intellectual disability","volume":"42","author":"Sakai","year":"2020","journal-title":"Brain Dev."},{"key":"10.1016\/j.bone.2026.117930_bb0015","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/j.1741-1130.2007.00104.x","article-title":"A need for a taxonomy for profound intellectual and multiple disabilities","volume":"4","author":"Nakken","year":"2007","journal-title":"J. Policy Pract. Intellect. Disabil."},{"key":"10.1016\/j.bone.2026.117930_bb0020","first-page":"42","article-title":"Report of questionnaire survey (in Japanese)","volume":"15","author":"Morishita","year":"2015","journal-title":"Bull. West. Jpn. Assoc. Inst. Children Severe Disabil."},{"key":"10.1016\/j.bone.2026.117930_bb0025","article-title":"Risk factors for long bone fractures in patients with severe motor and intellectual disabilities: a 6-year follow-up retrospective study","volume":"7","author":"Hagino","year":"2022","journal-title":"Prog. Rehabil. Med."},{"key":"10.1016\/j.bone.2026.117930_bb0030","doi-asserted-by":"crossref","DOI":"10.1542\/peds.110.1.e5","article-title":"Bone density and metabolism in children and adolescents with moderate to severe cerebral palsy","volume":"110","author":"Henderson","year":"2002","journal-title":"Pediatrics"},{"key":"10.1016\/j.bone.2026.117930_bb0035","doi-asserted-by":"crossref","DOI":"10.2340\/16501977-2789","article-title":"Bone quality in adults with severe motor and intellectual disabilities","volume":"53","author":"Sakai","year":"2021","journal-title":"J. Rehabil. Med."},{"key":"10.1016\/j.bone.2026.117930_bb0040","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1111\/j.1469-8749.2009.03384.x","article-title":"Epidemiology of low bone mineral density and fractures in children with severe cerebral palsy: a systematic review","volume":"51","author":"Mergler","year":"2009","journal-title":"Dev. Med. Child Neurol."},{"key":"10.1016\/j.bone.2026.117930_bb0045","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.braindev.2024.06.001","article-title":"Serum 25(OH)D and vitamin K1 levels in patients with severe motor and intellectual disability: a Japanese single-center experience","volume":"46","author":"Sakai","year":"2024","journal-title":"Brain Dev."},{"key":"10.1016\/j.bone.2026.117930_bb0050","doi-asserted-by":"crossref","first-page":"122","DOI":"10.3390\/nu16010122","article-title":"Vitamin D supplementation at a dose of 10 \u03bcg\/day in institutionalized children with severe motor and intellectual disabilities","volume":"16","author":"Sato","year":"2024","journal-title":"Nutrients"},{"key":"10.1016\/j.bone.2026.117930_bb0055","first-page":"1511","article-title":"How should clinicians manage osteoporosis in ankylosing spondylitis?","volume":"29","author":"Bessant","year":"2002","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.bone.2026.117930_bb0060","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1097\/01.brs.0000222030.32171.5f","article-title":"Discordantly high spinal bone mineral density values in patients with adult lumbar scoliosis","volume":"31","author":"Pappou","year":"2006","journal-title":"Spine"},{"key":"10.1016\/j.bone.2026.117930_bb0065","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1007\/s00774-004-0513-3","article-title":"Range of change of measured BMD in the femoral neck and total hip with rotation in women","volume":"22","author":"Rosenthall","year":"2004","journal-title":"J. Bone Miner. Metab."},{"key":"10.1016\/j.bone.2026.117930_bb0070","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1385\/JCD:6:2:143","article-title":"Prevalence of low bone density in institutionalized men with developmental disabilities","volume":"6","author":"Jaffe","year":"2003","journal-title":"J. Clin. Densitom."},{"key":"10.1016\/j.bone.2026.117930_bb0075","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.ultrasmedbio.2014.08.017","article-title":"A novel ultrasound methodology for estimating spine mineral density","volume":"41","author":"Conversano","year":"2015","journal-title":"Ultrasound Med. Biol."},{"key":"10.1016\/j.bone.2026.117930_bb0080","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s00198-018-4686-3","article-title":"Radiofrequency echographic multispectrometry compared with dual-energy X-ray absorptiometry for osteoporosis diagnosis on lumbar spine and femoral neck","volume":"30","author":"Di Paola","year":"2019","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2026.117930_bb0085","article-title":"Radiofrequency echographic multispectrometry (REMS) technology for bone health status evaluation in kidney transplant recipients","volume":"14","author":"Fassio","year":"2024","journal-title":"Diagnostics (Basel)"},{"key":"10.1016\/j.bone.2026.117930_bb0090","article-title":"Radiofrequency echographic multi-spectrometry-based measurement of bone mineral density in patients with severe motor and intellectual disability: an opportunity for patients with severe scoliosis and hip dislocation","volume":"22","author":"Sakai","year":"2024","journal-title":"Bone Rep."},{"key":"10.1016\/j.bone.2026.117930_bb0095","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.3758\/BRM.41.4.1149","article-title":"Statistical power analyses using G*Power 3.1: tests for correlation and regression analyses","volume":"41","author":"Faul","year":"2009","journal-title":"Behav. Res. Methods"},{"key":"10.1016\/j.bone.2026.117930_bb0100","doi-asserted-by":"crossref","first-page":"201","DOI":"10.5606\/tftrd.2017.595","article-title":"Effects of clinical reanalysis in dual energy X-ray absorptiometry reports","volume":"63","author":"Tuna","year":"2017","journal-title":"Turk. J. Phys. Med. Rehab."},{"key":"10.1016\/j.bone.2026.117930_bb0105","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1007\/s00198-015-3393-6","article-title":"Osteoporosis in adults with cerebral palsy: feasibility of DXA screening and risk factors for low bone density","volume":"27","author":"Marciniak","year":"2016","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.bone.2026.117930_bb0110","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/S8756-3282(00)00238-6","article-title":"Prediction of fracture from low bone mineral density measurements overestimates risk","volume":"26","author":"Kanis","year":"2000","journal-title":"Bone"},{"key":"10.1016\/j.bone.2026.117930_bb0115","doi-asserted-by":"crossref","first-page":"770","DOI":"10.5535\/arm.2012.36.6.770","article-title":"Factors affecting bone mineral density in adults with cerebral palsy","volume":"36","author":"Yoon","year":"2012","journal-title":"Ann. Rehabil. Med."},{"key":"10.1016\/j.bone.2026.117930_bb0120","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2021.733322","article-title":"Bone mineral density in adults with cerebral palsy","volume":"12","author":"Won","year":"2021","journal-title":"Front. Neurol."},{"key":"10.1016\/j.bone.2026.117930_bb0125","first-page":"573","article-title":"Bone\u2019s mechanostat: a 2003 update","volume":"33","author":"Frost","year":"2003","journal-title":"Anat Rec A Discov Mol Cell Evol Biol"},{"key":"10.1016\/j.bone.2026.117930_bb0130","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.jocd.2015.06.008","article-title":"Fracture risk prediction by non-BMD DXA measures: the 2015 ISCD official positions Part 2: trabecular bone score","volume":"18","author":"Silva","year":"2015","journal-title":"J. Clin. Densitom."}],"container-title":["Bone"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328226001560?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328226001560?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T15:27:40Z","timestamp":1784647660000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S8756328226001560"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":26,"alternative-id":["S8756328226001560"],"URL":"https:\/\/doi.org\/10.1016\/j.bone.2026.117930","relation":{},"ISSN":["8756-3282"],"issn-type":[{"value":"8756-3282","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Radiofrequency echographic multispectrometry assessment of osteoporosis in severe motor and intellectual disabilities: A cross-sectional study","name":"articletitle","label":"Article Title"},{"value":"Bone","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bone.2026.117930","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"117930"}}