{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T16:53:07Z","timestamp":1791996787058,"version":"4.4.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100005054","name":"Nantong University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bone"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.bone.2026.118029","type":"journal-article","created":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T00:44:26Z","timestamp":1784853866000},"page":"118029","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Potential physiological determinants of diagnostic discordance between an MRI-derived lumbar vertebral bone quality score and DXA T-scores"],"prefix":"10.1016","volume":"212","author":[{"given":"Jie","family":"Hao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fayao","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongqi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tongrui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4823-0587","authenticated-orcid":false,"given":"Xingjie","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.bone.2026.118029_bb0005","doi-asserted-by":"crossref","first-page":"84","DOI":"10.3171\/2023.8.SPINE23450","article-title":"Evaluating alternatives to dual-energy X-ray absorptiometry for assessing bone quality in patients undergoing spine surgery","volume":"40","author":"Courtois","year":"2024","journal-title":"J. Neurosurg. Spine"},{"issue":"4","key":"10.1016\/j.bone.2026.118029_bb0010","doi-asserted-by":"crossref","first-page":"436","DOI":"10.3171\/2022.11.SPINE22875","article-title":"Alternatives to DXA for the assessment of bone density: a systematic review of the literature and future recommendations","volume":"38","author":"Deshpande","year":"2023","journal-title":"J. Neurosurg. Spine"},{"issue":"9","key":"10.1016\/j.bone.2026.118029_bb0015","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1007\/s11547-025-02029-4","article-title":"Emerging MRI-based spine scoring techniques targeting bone quality to assess osteoporosis, vertebral fracture risk, other spinal degenerative diseases, and postsurgical outcomes","volume":"130","author":"Din","year":"2025","journal-title":"Radiol. Med."},{"issue":"1","key":"10.1016\/j.bone.2026.118029_bb0020","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1007\/s11657-025-01509-4","article-title":"Assessment of osteoporosis and vertebral fractures with T1- and T2-weighted MRI scans","volume":"20","author":"Din","year":"2025","journal-title":"Arch. Osteoporos."},{"issue":"4","key":"10.1016\/j.bone.2026.118029_bb0025","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1007\/s00198-012-2048-0","article-title":"Degenerative changes at the lumbar spine\u2014implications for bone mineral density measurement in elderly women","volume":"24","author":"Tenne","year":"2013","journal-title":"Osteoporos. Int."},{"issue":"9","key":"10.1016\/j.bone.2026.118029_bb0030","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1016\/j.acra.2020.07.028","article-title":"Operator-related errors and pitfalls in dual energy X-ray absorptiometry: how to recognize and avoid them","volume":"28","author":"Albano","year":"2021","journal-title":"Acad. Radiol."},{"issue":"3","key":"10.1016\/j.bone.2026.118029_bb0035","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1002\/mp.16057","article-title":"Quantifying misdiagnosis rates from cross-calibration biases and precision errors in dual-energy X-ray absorptiometry of the femoral neck","volume":"50","author":"Fahrenholtz","year":"2023","journal-title":"Med. Phys."},{"issue":"1","key":"10.1016\/j.bone.2026.118029_bb0040","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.spinee.2020.05.540","article-title":"Vertebral bone quality score predicts fragility fractures independently of bone mineral density","volume":"21","author":"Ehresman","year":"2021","journal-title":"Spine J."},{"issue":"12","key":"10.1016\/j.bone.2026.118029_bb0045","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1016\/j.spinee.2022.08.002","article-title":"Vertebral bone quality score independently predicts cage subsidence following transforaminal lumbar interbody fusion","volume":"22","author":"Soliman","year":"2022","journal-title":"Spine J."},{"issue":"2","key":"10.1016\/j.bone.2026.118029_bb0050","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1227\/neu.0000000000002864","article-title":"Vertebral bone quality score as a predictor of adjacent segment disease after lumbar interbody fusion","volume":"95","author":"Kuo","year":"2024","journal-title":"Neurosurgery"},{"issue":"5","key":"10.1016\/j.bone.2026.118029_bb0055","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1227\/neu.0000000000002291","article-title":"Vertebral bone quality score independently predicts proximal junctional kyphosis and\/or failure after adult spinal deformity surgery","volume":"92","author":"Kuo","year":"2023","journal-title":"Neurosurgery"},{"issue":"23","key":"10.1016\/j.bone.2026.118029_bb0060","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1097\/BRS.0000000000004577","article-title":"Vertebral bone quality score as a predictor of pedicle screw loosening following surgery for degenerative lumbar disease","volume":"48","author":"Li","year":"2023","journal-title":"Spine"},{"issue":"11","key":"10.1016\/j.bone.2026.118029_bb0065","doi-asserted-by":"crossref","first-page":"1866","DOI":"10.1016\/j.spinee.2022.06.003","article-title":"Patient physiology influences the MRI-based vertebral bone quality score","volume":"22","author":"Aynaszyan","year":"2022","journal-title":"Spine J."},{"issue":"6","key":"10.1016\/j.bone.2026.118029_bb0070","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1007\/s11914-016-0332-1","article-title":"Advanced glycation end products, diabetes, and bone strength","volume":"14","author":"Yamamoto","year":"2016","journal-title":"Curr. Osteoporos. Rep."},{"issue":"11","key":"10.1016\/j.bone.2026.118029_bb0075","doi-asserted-by":"crossref","first-page":"2767","DOI":"10.1111\/liv.14630","article-title":"Bilirubin and bile acids in osteocytes and bone tissue: potential role in cholestatic-induced osteoporosis","volume":"40","author":"Ruiz-Gasp\u00e0","year":"2020","journal-title":"Liver Int."},{"issue":"3","key":"10.1016\/j.bone.2026.118029_bb0080","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1097\/BRS.0000000000005406","article-title":"Potential physiological factors underlying diagnostic discrepancies between MRI-based cervical vertebral bone quality scores and dual-energy X-ray absorptiometry T-scores","volume":"51","author":"Wang","year":"2026","journal-title":"Spine"},{"issue":"4","key":"10.1016\/j.bone.2026.118029_bb0085","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.spinee.2019.10.018","article-title":"Novel MRI-based score for assessment of bone density in operative spine patients","volume":"20","author":"Ehresman","year":"2020","journal-title":"Spine J."},{"issue":"4","key":"10.1016\/j.bone.2026.118029_bb0090","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1177\/21925682221138261","article-title":"Preoperative assessment of bone density using MRI-based vertebral bone quality score modified for patients undergoing cervical spine surgery","volume":"14","author":"Huang","year":"2024","journal-title":"Global Spine Journal."},{"issue":"1","key":"10.1016\/j.bone.2026.118029_bb0095","article-title":"MRI-based vertebral bone quality score for the assessment of osteoporosis in patients undergoing surgery for lumbar degenerative diseases","volume":"18","author":"Chen","year":"2023","journal-title":"J. Orthop. Surg. Res."},{"issue":"10","key":"10.1016\/j.bone.2026.118029_bb0100","doi-asserted-by":"crossref","first-page":"7561","DOI":"10.21037\/qims-24-532","article-title":"Diagnostic value of a magnetic resonance imaging-based vertebral bone quality score for bone mineral density assessment: an updated systematic review and meta-analysis","volume":"14","author":"Yang","year":"2024","journal-title":"Quant. Imaging Med. Surg."},{"issue":"1","key":"10.1016\/j.bone.2026.118029_bb0105","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1007\/s00586-022-07484-5","article-title":"Comparison of cervical, thoracic, and lumbar vertebral bone quality scores for increased utility of bone mineral density screening","volume":"32","author":"Razzouk","year":"2023","journal-title":"Eur. Spine J."},{"key":"10.1016\/j.bone.2026.118029_bb0110","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2015.00165","article-title":"High cholesterol deteriorates bone health: new insights into molecular mechanisms","volume":"6","author":"Mandal","year":"2015","journal-title":"Front. Endocrinol."},{"issue":"12","key":"10.1016\/j.bone.2026.118029_bb0115","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1007\/s10654-004-1706-8","article-title":"Atherogenic lipid profile and elevated lipoprotein(a) are associated with lower bone mineral density in early postmenopausal overweight women","volume":"19","author":"Orozco","year":"2004","journal-title":"Eur. J. Epidemiol."},{"key":"10.1016\/j.bone.2026.118029_bb0120","article-title":"High cholesterol and low triglycerides are associated with total lumbar bone mineral density among adults aged 50 years and over: NHANES 2017\u20132020","volume":"9","author":"Wang","year":"2022","journal-title":"Front. Med."},{"issue":"4","key":"10.1016\/j.bone.2026.118029_bb0125","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1172\/JCI77716","article-title":"MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation","volume":"125","author":"Li","year":"2015","journal-title":"J. Clin. Invest."},{"issue":"2","key":"10.1016\/j.bone.2026.118029_bb0130","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1007\/s11914-015-0260-5","article-title":"Diabetes, diabetic complications, and fracture risk","volume":"13","author":"Oei","year":"2015","journal-title":"Curr. Osteoporos. Rep."},{"issue":"5","key":"10.1016\/j.bone.2026.118029_bb0135","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s10654-012-9674-x","article-title":"Association between bone mineral density and type 2 diabetes mellitus: a meta-analysis of observational studies","volume":"27","author":"Ma","year":"2012","journal-title":"Eur. J. Epidemiol."},{"issue":"15","key":"10.1016\/j.bone.2026.118029_bb0140","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.2106\/JBJS.18.01297","article-title":"Bone quality and fracture healing in type 1 and type 2 diabetes mellitus","volume":"101","author":"Henderson","year":"2019","journal-title":"J. Bone Joint Surg. Am."},{"issue":"7","key":"10.1016\/j.bone.2026.118029_bb0145","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1007\/s00198-014-2704-7","article-title":"Bone quality assessment in type 2 diabetes mellitus","volume":"25","author":"Dhaliwal","year":"2014","journal-title":"Osteoporos. Int."},{"issue":"2","key":"10.1016\/j.bone.2026.118029_bb0150","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1210\/jc.2012-3118","article-title":"TBS (trabecular bone score) and diabetes-related fracture risk","volume":"98","author":"Leslie","year":"2013","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.bone.2026.118029_bb0155","article-title":"The association between total bile acid and bone mineral density among patients with type 2 diabetes","volume":"14","author":"Yang","year":"2023","journal-title":"Front. Endocrinol."}],"container-title":["Bone"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328226002553?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328226002553?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T16:39:46Z","timestamp":1791995986000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S8756328226002553"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":31,"alternative-id":["S8756328226002553"],"URL":"https:\/\/doi.org\/10.1016\/j.bone.2026.118029","relation":{},"ISSN":["8756-3282"],"issn-type":[{"value":"8756-3282","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Potential physiological determinants of diagnostic discordance between an MRI-derived lumbar vertebral bone quality score and DXA T-scores","name":"articletitle","label":"Article Title"},{"value":"Bone","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bone.2026.118029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"118029"}}