{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:02:21Z","timestamp":1790740941702,"version":"4.1.0"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003356","name":"Gazi University","doi-asserted-by":"publisher","award":["7286"],"award-info":[{"award-number":["7286"]}],"id":[{"id":"10.13039\/501100003356","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bone"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.bone.2026.118036","type":"journal-article","created":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T15:28:12Z","timestamp":1785770892000},"page":"118036","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Prepubertal blue light exposure alters growth plate morphology and hormonal expression"],"prefix":"10.1016","volume":"213","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1265-4952","authenticated-orcid":false,"given":"Aylin K\u0131l\u0131n\u00e7","family":"U\u011furlu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duygu","family":"Dayan\u0131r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fclnur Take","family":"Kaplano\u011flu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fe M\u00fcr\u015fide","family":"Demirel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6zlem","family":"G\u00fclbahar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuba Saadet Deveci","family":"Bulut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esra","family":"D\u00f6\u011fer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Orhun","family":"\u00c7amurdan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aysun","family":"Bideci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bone.2026.118036_bb0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.dcn.2022.101150","article-title":"Youth screen use in the ABCD\u00ae study","volume":"57","author":"Bagot","year":"2022","journal-title":"Dev. Cogn. Neurosci."},{"key":"10.1016\/j.bone.2026.118036_bb0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/bmjopen-2016-014585","article-title":"Correlates of mobile screen media use among children aged 0-8: a systematic review","volume":"7","author":"Paudel","year":"2017","journal-title":"BMJ Open"},{"key":"10.1016\/j.bone.2026.118036_bb0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-022-05840-5","article-title":"Young children\u2019s screen time during the first COVID-19 lockdown in 12 countries","volume":"12","author":"Bergmann","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bone.2026.118036_bb0020","doi-asserted-by":"crossref","DOI":"10.1038\/s44323-025-00029-1","article-title":"Beyond vision: effects of light on the circadian clock and mood-related behaviours","volume":"2","author":"Stewart","year":"2025","journal-title":"Npj Biological Timing and Sleep"},{"key":"10.1016\/j.bone.2026.118036_bb0025","doi-asserted-by":"crossref","DOI":"10.3389\/fphot.2023.1272934","article-title":"Lights should support circadian rhythms: evidence-based scientific consensus","volume":"4","author":"Moore-Ede","year":"2023","journal-title":"Frontiers in Photonics"},{"key":"10.1016\/j.bone.2026.118036_bb0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13052-021-01015-6","article-title":"Impact of COVID-19 pandemic lockdown on early onset of puberty: experience of an Italian tertiary center","volume":"47","author":"Verzani","year":"2021","journal-title":"Ital. J. Pediatr."},{"key":"10.1016\/j.bone.2026.118036_bb0035","first-page":"1","article-title":"COVID-19 pandemic phases and female precocious puberty: the experience of the past 4 years (2019 through 2022) in an Italian tertiary center","author":"Chioma","year":"2023","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.bone.2026.118036_bb0040","doi-asserted-by":"crossref","DOI":"10.1530\/EC-21-0650","article-title":"Sedentary lifestyle and precocious puberty in girls during the COVID-19 pandemic: an Italian experience","volume":"11","author":"Chioma","year":"2022","journal-title":"Endocr. Connect."},{"key":"10.1016\/j.bone.2026.118036_bb0045","first-page":"1","article-title":"The reason of increasing puberty precocious cases during the pandemic period: obesity or not?","author":"G\u00fcndo\u011fan","year":"2023","journal-title":"Turk. J. Pediatr. Dis."},{"key":"10.1016\/j.bone.2026.118036_bb0050","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/9229153","article-title":"Analysis of the incidence and risk factors of precocious puberty in girls during the COVID-19 pandemic","volume":"2022","author":"Fu","year":"2022","journal-title":"Int. J. Endocrinol."},{"key":"10.1016\/j.bone.2026.118036_bb0055","doi-asserted-by":"crossref","first-page":"349","DOI":"10.5152\/TurkArchPediatr.2022.2101313","article-title":"Status of central precocious puberty cases at the onset of coronavirus disease 2019 pandemic: a single-center experience","volume":"57","author":"Orman","year":"2022","journal-title":"Turk. Arch. Pediatr."},{"key":"10.1016\/j.bone.2026.118036_bb0060","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1007\/s11914-020-00570-x","article-title":"The actions of IGF-1 in the growth plate and its role in postnatal bone elongation","volume":"18","author":"Racine","year":"2020","journal-title":"Curr. Osteoporos. Rep."},{"key":"10.1016\/j.bone.2026.118036_bb0065","article-title":"Annual review of nutrition nutrition, other environmental influences, and genetics in the determination of human stature","volume":"21","author":"Lui","year":"2025"},{"key":"10.1016\/j.bone.2026.118036_bb0070","doi-asserted-by":"crossref","first-page":"553","DOI":"10.3345\/cep.2023.00346","article-title":"Growth plate closure and therapeutic interventions","volume":"67","author":"Cho","year":"2024","journal-title":"Clin Exp Pediatr"},{"key":"10.1016\/j.bone.2026.118036_bb0075","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2023.1190445","article-title":"Is blue light exposure a cause of precocious puberty in male rats?","volume":"14","author":"U\u011furlu","year":"2023","journal-title":"Front. Endocrinol. (Lausanne)"},{"key":"10.1016\/j.bone.2026.118036_bb0080","doi-asserted-by":"crossref","first-page":"365","DOI":"10.4274\/jcrpe.galenos.2023.2022-12-1","article-title":"Effects of blue light on puberty and ovary in female rats","volume":"15","author":"U\u011furlu","year":"2023","journal-title":"J. Clin. Res. Pediatr. Endocrinol."},{"key":"10.1016\/j.bone.2026.118036_bb0085","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1258\/la.2012.150312","article-title":"Guide for the care and use of laboratory animals (8th edn)","volume":"46","author":"Albus","year":"2012","journal-title":"Lab. Anim."},{"key":"10.1016\/j.bone.2026.118036_bb0090","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.brainresrev.2005.07.002","article-title":"A model of phototransduction by the human circadian system","volume":"50","author":"Rea","year":"2005","journal-title":"Brain Res. Rev."},{"key":"10.1016\/j.bone.2026.118036_bb0095","first-page":"1","article-title":"Regulation of the mammalian pineal","volume":"284","author":"Lucas","year":"1999","journal-title":"Science (1979)"},{"key":"10.1016\/j.bone.2026.118036_bb0100","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/eye.1999.142","article-title":"Blue light induced apoptosis in rat retina","volume":"13","author":"Wu","year":"1999","journal-title":"Eye"},{"issue":"6","key":"10.1016\/j.bone.2026.118036_bb0105","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1093\/sleep\/33.6.833","article-title":"Endogenous melatonin is not obligatory for the regulation of the rat sleep-wake cycle","volume":"33","author":"Fisher","year":"2010","journal-title":"Sleep"},{"key":"10.1016\/j.bone.2026.118036_bb0110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep46381","article-title":"Development and validation of a method for precise dating of female puberty in laboratory rodents: the puberty ovarian maturation score (pub-score)","volume":"7","author":"Gaytan","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bone.2026.118036_bb0115","first-page":"41","article-title":"Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring","author":"Avci","year":"2013","journal-title":"Semin. Cutan. Med. Surg."},{"key":"10.1016\/j.bone.2026.118036_bb0120","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1016\/j.jaad.2021.02.048","article-title":"Visible light. Part I: properties and cutaneous effects of visible light","volume":"84","author":"Austin","year":"2021","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1016\/j.bone.2026.118036_bb0125","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1002\/lsm.20952","article-title":"Prophylactic low-level light therapy for the treatment of hypertrophic scars and keloids: a case series","volume":"42","author":"Barolet","year":"2010","journal-title":"Lasers Surg. Med."},{"key":"10.1016\/j.bone.2026.118036_bb0130","doi-asserted-by":"crossref","DOI":"10.1100\/2012\/231723","article-title":"The effects of low-level laser therapy, 670nm, on epiphyseal growth in rats","volume":"2012","author":"De Andrade","year":"2012","journal-title":"Sci. World J."},{"issue":"8","key":"10.1016\/j.bone.2026.118036_bb0135","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1097\/SCS.0000000000003068","article-title":"The comparison of the efficacy of blue light-emitting diode light and 980-nm low-level laser light on bone regeneration","volume":"27","author":"Dereci","year":"2016","journal-title":"J. Craniofac. Surg."},{"key":"10.1016\/j.bone.2026.118036_bb0140","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1139\/bcb-2023-0025","article-title":"Dysregulation of insulin-like growth factor-1 signaling in postnatal bone elongation","volume":"101","author":"White","year":"2023","journal-title":"Biochem. Cell Biol."},{"issue":"4","key":"10.1016\/j.bone.2026.118036_bb0145","first-page":"157","article-title":"Endocrine regulation of the growth plate","volume":"64","author":"Nilsson","year":"2005","journal-title":"Horm. Res."},{"issue":"17","key":"10.1016\/j.bone.2026.118036_bb0150","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202401298R","article-title":"IGF signaling pathway in bone and cartilage development, homeostasis, and disease","volume":"38","author":"Ruan","year":"2024","journal-title":"FASEB J."},{"key":"10.1016\/j.bone.2026.118036_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.ghir.2026.101679","article-title":"The growth plate: zonal architecture, plasticity, and endocrine control of linear growth","volume":"83","author":"Ostria","year":"2026","journal-title":"Growth Hormon. IGF Res."},{"issue":"5","key":"10.1016\/j.bone.2026.118036_bb0160","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1210\/endrev\/bnad008","article-title":"Signaling pathways of the insulin-like growth factor binding proteins","volume":"44","author":"Baxter","year":"2023","journal-title":"Endocr. Rev."}],"container-title":["Bone"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328226002620?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S8756328226002620?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:41:21Z","timestamp":1790739681000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S8756328226002620"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":32,"alternative-id":["S8756328226002620"],"URL":"https:\/\/doi.org\/10.1016\/j.bone.2026.118036","relation":{},"ISSN":["8756-3282"],"issn-type":[{"value":"8756-3282","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prepubertal blue light exposure alters growth plate morphology and hormonal expression","name":"articletitle","label":"Article Title"},{"value":"Bone","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bone.2026.118036","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"118036"}}