{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T17:06:34Z","timestamp":1763831194273,"version":"build-2065373602"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,12,7]],"date-time":"2020-12-07T00:00:00Z","timestamp":1607299200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bone Reports"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1016\/j.bonr.2020.100739","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T05:49:56Z","timestamp":1607579396000},"page":"100739","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Effect of ErhBMP-2-loaded \u03b2-tricalcium phosphate on ulna defects in the osteoporosis rabbit model"],"prefix":"10.1016","volume":"14","author":[{"given":"Tse-Yin","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang-Chin","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pei-Wei","family":"Weng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian-Ming","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Ling","family":"Yeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.bonr.2020.100739_bb0005","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.cden.2005.11.006","article-title":"The engineering of craniofacial tissues in the laboratory: a review of biomaterials for scaffolds and implant coatings","volume":"50","author":"Abukawa","year":"2006","journal-title":"Dent. Clin. N. Am."},{"key":"10.1016\/j.bonr.2020.100739_bb0010","doi-asserted-by":"crossref","unstructured":"Anon Osteoporosis prevention, diagnosis, and therapy. Jama, 2001. 285(6): p. 785\u201395.","DOI":"10.1001\/jama.285.6.785"},{"key":"10.1016\/j.bonr.2020.100739_bb0015","doi-asserted-by":"crossref","unstructured":"Benglis, D., M.Y. Wang, and A.D. Levi, A comprehensive review of the safety profile of bone morphogenetic protein in spine surgery. Neurosurgery, 2008. 62(5 Suppl 2): p. ONS423\u201331; discussion ONS431.","DOI":"10.1227\/01.neu.0000326030.24220.d8"},{"issue":"Suppl. 2","key":"10.1016\/j.bonr.2020.100739_bb0020","doi-asserted-by":"crossref","first-page":"S56","DOI":"10.1016\/j.injury.2011.06.011","article-title":"The use of bone-graft substitutes in large bone defects: any specific needs?","volume":"42","author":"Calori","year":"2011","journal-title":"Injury"},{"issue":"334","key":"10.1016\/j.bonr.2020.100739_bb0025","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.morpho.2017.09.001","article-title":"Beta-tricalcium phosphate and bone surgery: editorial","volume":"101","author":"Chappard","year":"2017","journal-title":"Morphologie"},{"issue":"Suppl. 2","key":"10.1016\/j.bonr.2020.100739_bb0030","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1016\/S0020-1383(16)47004-X","article-title":"Fracture healing in osteoporotic bone","volume":"47","author":"Cheung","year":"2016","journal-title":"Injury"},{"issue":"Suppl. 1","key":"10.1016\/j.bonr.2020.100739_bb0035","doi-asserted-by":"crossref","first-page":"S101","DOI":"10.1007\/s40520-013-0088-8","article-title":"Autograft, allograft and bone substitutes in reconstructive orthopedic surgery","volume":"25","author":"Chiarello","year":"2013","journal-title":"Aging Clin. Exp. Res."},{"issue":"5","key":"10.1016\/j.bonr.2020.100739_bb0040","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1111\/cid.12522","article-title":"Histologic and histomorphometric assessment of sinus-floor augmentation with beta-tricalcium phosphate alone or in combination with pure-platelet-rich plasma or platelet-rich fibrin: a randomized clinical trial","volume":"19","author":"Comert Kilic","year":"2017","journal-title":"Clin. Implant. Dent. Relat. Res."},{"issue":"1","key":"10.1016\/j.bonr.2020.100739_bb0045","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1002\/jbmr.1805","article-title":"Standardized nomenclature, symbols, and units for bone histomorphometry: a 2012 update of the report of the ASBMR histomorphometry nomenclature committee","volume":"28","author":"Dempster","year":"2013","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bonr.2020.100739_bb0050","doi-asserted-by":"crossref","unstructured":"Fillingham, Y. and J. Jacobs, Bone grafts and their substitutes. Bone Joint J, 2016. 98-b(1 Suppl A): p. 6\u20139.","DOI":"10.1302\/0301-620X.98B.36350"},{"issue":"11","key":"10.1016\/j.bonr.2020.100739_bb0055","doi-asserted-by":"crossref","first-page":"4605","DOI":"10.1210\/endo.137.11.8895323","article-title":"The effects of aging on the bone inductive activity of recombinant human bone morphogenetic protein-2","volume":"137","author":"Fleet","year":"1996","journal-title":"Endocrinology"},{"key":"10.1016\/j.bonr.2020.100739_bb0060","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1097\/00003086-199706000-00011","article-title":"Autogenous iliac crest bone graft","volume":"339","author":"Goulet","year":"1997","journal-title":"Complications and functional assessment. Clin Orthop Relat Res"},{"issue":"Suppl. 2","key":"10.1016\/j.bonr.2020.100739_bb0065","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.injury.2014.04.002","article-title":"Delayed union and nonunions: epidemiology, clinical issues, and financial aspects","volume":"45","author":"Hak","year":"2014","journal-title":"Injury"},{"issue":"334","key":"10.1016\/j.bonr.2020.100739_bb0070","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.morpho.2017.03.005","article-title":"Beta-tricalcium phosphate for orthopedic reconstructions as an alternative to autogenous bone graft","volume":"101","author":"Hernigou","year":"2017","journal-title":"Morphologie"},{"issue":"3","key":"10.1016\/j.bonr.2020.100739_bb0075","doi-asserted-by":"crossref","first-page":"161","DOI":"10.4047\/jap.2011.3.3.161","article-title":"Randomized clinical trial on the efficacy of Escherichia coli-derived rhBMP-2 with beta-TCP\/HA in extraction socket","volume":"3","author":"Huh","year":"2011","journal-title":"J Adv Prosthodont"},{"issue":"3","key":"10.1016\/j.bonr.2020.100739_bb0080","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.jds.2017.01.003","volume":"12","author":"Kim","year":"2017","journal-title":"J Dent Sci"},{"issue":"3","key":"10.1016\/j.bonr.2020.100739_bb0085","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1002\/jbm.a.36833","article-title":"Local application of alendronate controls bone formation and beta-tricalcium phosphate resorption induced by recombinant human bone morphogenetic protein-2","volume":"108","author":"Kitasato","year":"2019","journal-title":"J. Biomed. Mater. Res. A"},{"issue":"29","key":"10.1016\/j.bonr.2020.100739_bb0090","doi-asserted-by":"crossref","first-page":"5118","DOI":"10.1016\/j.biomaterials.2006.05.031","article-title":"Repair of segmental bone defects in rabbit tibiae using a complex of beta-tricalcium phosphate, type I collagen, and fibroblast growth factor-2","volume":"27","author":"Komaki","year":"2006","journal-title":"Biomaterials"},{"issue":"5\u20136","key":"10.1016\/j.bonr.2020.100739_bb0095","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0960-0760(99)00032-1","article-title":"Osteoporosis influences the late period of fracture healing in a rat model prepared by ovariectomy and low calcium diet","volume":"68","author":"Kubo","year":"1999","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.bonr.2020.100739_bb0100","first-page":"10(4)","author":"Lowery","year":"2018","journal-title":"Cold Spring Harb. Perspect. Biol."},{"issue":"3","key":"10.1016\/j.bonr.2020.100739_bb0105","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1034\/j.1600-0765.2001.360306.x","article-title":"Effect of aging on bone formation induced by recombinant human bone morphogenetic protein-2 combined with fibrous collagen membranes at subperiosteal sites","volume":"36","author":"Matsumoto","year":"2001","journal-title":"J. Periodontal Res."},{"issue":"10","key":"10.1016\/j.bonr.2020.100739_bb0110","doi-asserted-by":"crossref","first-page":"e15","DOI":"10.1016\/j.spinee.2013.05.024","article-title":"Acute epidural lipedema: a novel entity and potential complication of bone morphogenetic protein use in lumbar spine fusion","volume":"13","author":"Merrick","year":"2013","journal-title":"Spine J."},{"issue":"1","key":"10.1016\/j.bonr.2020.100739_bb0115","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/S8756-3282(00)00414-2","article-title":"Osteoporosis influences the early period of fracture healing in a rat osteoporotic model","volume":"28","author":"Namkung-Matthai","year":"2001","journal-title":"Bone"},{"issue":"5","key":"10.1016\/j.bonr.2020.100739_bb0120","first-page":"490","article-title":"Donor site morbidity following iliac crest bone graft","volume":"57","author":"Palmer","year":"2008","journal-title":"West Indian Med J"},{"issue":"4","key":"10.1016\/j.bonr.2020.100739_bb0125","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/s00774-019-01007-x","article-title":"Rabbit as model for osteoporosis research","volume":"37","author":"Permuy","year":"2019","journal-title":"J. Bone Miner. Metab."},{"year":"2017","series-title":"BMP delivery systems for bone regeneration: Healthy vs osteoporotic population","author":"Segredo-Morales","key":"10.1016\/j.bonr.2020.100739_bb0130"},{"issue":"5","key":"10.1016\/j.bonr.2020.100739_bb0135","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.joca.2008.01.002","article-title":"Animal models for osteoarthritis: the effect of ovariectomy and estrogen treatment - a systematic approach","volume":"16","author":"Sniekers","year":"2008","journal-title":"Osteoarthr. Cartil."},{"issue":"6","key":"10.1016\/j.bonr.2020.100739_bb0140","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.21873\/invivo.11398","article-title":"Application of platelet-rich plasma and tricalcium phosphate in the treatment of comminuted fractures in animals","volume":"32","author":"Szponder","year":"2018","journal-title":"In Vivo"},{"key":"10.1016\/j.bonr.2020.100739_bb0145","doi-asserted-by":"crossref","first-page":"98","DOI":"10.2174\/1874120701206010098","article-title":"Use of an injectable complex of beta-tricalcium phosphate granules, hyaluronate, and fibroblast growth Factor-2 on repair of unstable intertrochanteric fractures","volume":"6","author":"Tanaka","year":"2012","journal-title":"Open Biomed Eng J"},{"issue":"1","key":"10.1016\/j.bonr.2020.100739_bb0150","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/s11657-018-0422-z","article-title":"Microstructural properties of trabecular bone autografts: comparison of men and women with and without osteoporosis","volume":"13","author":"Xie","year":"2018","journal-title":"Arch. Osteoporos."},{"key":"10.1016\/j.bonr.2020.100739_bb0155","doi-asserted-by":"crossref","unstructured":"Zhou, S., et al., Estrogen modulates estrogen receptor alpha and beta expression, osteogenic activity, and apoptosis in mesenchymal stem cells (MSCs) of osteoporotic mice. J Cell Biochem Suppl, 2001. Suppl 36: p. 144\u201355.","DOI":"10.1002\/jcb.1096"}],"container-title":["Bone Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S235218722030499X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S235218722030499X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T16:24:56Z","timestamp":1762446296000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S235218722030499X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":31,"alternative-id":["S235218722030499X"],"URL":"https:\/\/doi.org\/10.1016\/j.bonr.2020.100739","relation":{},"ISSN":["2352-1872"],"issn-type":[{"type":"print","value":"2352-1872"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of ErhBMP-2-loaded \u03b2-tricalcium phosphate on ulna defects in the osteoporosis rabbit model","name":"articletitle","label":"Article Title"},{"value":"Bone Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bonr.2020.100739","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100739"}}