{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T08:00:31Z","timestamp":1776412831361,"version":"3.51.2"},"reference-count":96,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Best Practice & Research Clinical Anaesthesiology"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1016\/j.bpa.2017.02.001","type":"journal-article","created":{"date-parts":[[2017,2,9]],"date-time":"2017-02-09T05:16:40Z","timestamp":1486617400000},"page":"107-124","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"title":["Managing major obstetric haemorrhage: Pharmacotherapy and transfusion"],"prefix":"10.1016","volume":"31","author":[{"given":"Rachel","family":"Collis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilia","family":"Guasch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bpa.2017.02.001_bib1","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1097\/ACO.0000000000000079","article-title":"Quantifying severe maternal morbidity in Scotland: a continuous audit since 2003","volume":"27","author":"Marr","year":"2014","journal-title":"Curr Opin Anaesthesiol"},{"issue":"Suppl. 4","key":"10.1016\/j.bpa.2017.02.001_bib2","first-page":"53","article-title":"National committee on confidential enquiries into maternal deaths in South Africa. The confidential enquiry into maternal deaths in South Africa: a case study","volume":"121","author":"J1","year":"2014","journal-title":"BJOG"},{"key":"10.1016\/j.bpa.2017.02.001_bib3","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.ajog.2013.07.007","article-title":"Incidence, risk factors, and temporal trends in severe postpartum hemorrhage","volume":"209","author":"Kramer","year":"2013","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.bpa.2017.02.001_bib4","article-title":"Prevention and management of postpartum haemorrhage","author":"Mavrides","year":"2016","journal-title":"BJOG"},{"issue":"9726","key":"10.1016\/j.bpa.2017.02.001_bib5","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1016\/S0140-6736(10)60518-1","article-title":"Maternal mortality for 181 countries, 1980\u20132008: a systematic analysis of progress towards Millennium Development Goal 5","volume":"375","author":"Hogan","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.bpa.2017.02.001_bib6","series-title":"Saving lives, improving mothers' care. Lessons learned to inform future maternity care from the UK and Ireland Confidential Enquiries into Maternal Deaths and Morbidity 2009\u20132012","year":"2014"},{"key":"10.1016\/j.bpa.2017.02.001_bib7","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1111\/1471-0528.13477","article-title":"Invasive therapies for primary postpartum haemorrhage: a population-based study in France","volume":"123","author":"Kayem","year":"2016","journal-title":"BJOG"},{"key":"10.1016\/j.bpa.2017.02.001_bib8","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1097\/AOG.0b013e31829fc38c","article-title":"Ten years of confidential inquiries into maternal deaths in France, 1998\u20132007","volume":"122","author":"Saucedo","year":"2013","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.bpa.2017.02.001_bib9","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1111\/j.1471-0528.2011.03097.x","article-title":"Saving mothers' lives. Reviewing maternal deaths to make motherhood safer: 2006\u20132008","volume":"118","author":"Wilkinson","year":"2011","journal-title":"BJOG"},{"key":"10.1016\/j.bpa.2017.02.001_bib10","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1111\/j.1471-0528.2009.02382.x","article-title":"Rise in maternal mortality in the Netherlands","volume":"117","author":"Schutte","year":"2010","journal-title":"BJOG"},{"key":"10.1016\/j.bpa.2017.02.001_bib11","series-title":"Rapport du Comit\u00e9 National d'experts sur la Mortalit\u00e9 Maternelle (CNEMM)","author":"Enqu\u00e8te Nationale Confidentielle sur les Morts Maternelles, France 2007\u20132009","year":"2013"},{"key":"10.1016\/j.bpa.2017.02.001_bib12","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.jogn.2015.12.003","article-title":"Postpartum hemorrhage preparedness elements vary among hospitals in New Jersey and Georgia","volume":"45","author":"Bingham","year":"2016","journal-title":"J\u00a0Obstet Gynecol Neonatal Nurs"},{"key":"10.1016\/j.bpa.2017.02.001_bib13","doi-asserted-by":"crossref","first-page":"368.e1","DOI":"10.1016\/j.ajog.2011.06.084","article-title":"Comprehensive maternal hemorrhage protocols improve patient safety and reduce utilization of blood products","volume":"205","author":"Shields","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.bpa.2017.02.001_bib14","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.ajog.2014.07.012","article-title":"Comprehensive maternal hemorrhage protocols reduce the use of blood products and improve patient safety","volume":"212","author":"Shields","year":"2015","journal-title":"Am J Obstet Gynecol"},{"issue":"Suppl. 1","key":"10.1016\/j.bpa.2017.02.001_bib15","first-page":"S15","article-title":"The effects of audit and research in postpartum haemorrhage: benefits for all!","volume":"26","author":"Moses","year":"2016","journal-title":"Int J Obstet Anesth"},{"key":"10.1016\/j.bpa.2017.02.001_bib16","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1111\/j.1471-0528.2006.01018.x","article-title":"Improving the accuracy of estimated blood loss at obstetric haemorrhage using clinical reconstructions","volume":"113","author":"Bose","year":"2006","journal-title":"BJOG"},{"issue":"7294","key":"10.1016\/j.bpa.2017.02.001_bib17","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1136\/bmj.322.7294.1089","article-title":"Incidence and predictors of severe obstetric morbidity: case-control study","volume":"322","author":"Waterstone","year":"2001","journal-title":"BMJ"},{"key":"10.1016\/j.bpa.2017.02.001_bib18","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.ijoa.2010.12.002","article-title":"Standard haemostatic tests following major obstetric haemorrhage","volume":"20","author":"de Lloyd","year":"2011","journal-title":"Int J Obstet Anesth"},{"key":"10.1016\/j.bpa.2017.02.001_bib19","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ijoa.2014.07.009","article-title":"Measurement of blood loss during postpartum haemorrhage","volume":"24","author":"Lilley","year":"2015","journal-title":"Int J Obstet Anesth"},{"key":"10.1016\/j.bpa.2017.02.001_bib20","unstructured":"Association of Women's Health, Obstetric and Neonatal Nurses. Quantifying bloodloss video. https:\/\/www.awhonn.org\/?page=PPH. [accessed 8 January 2017]."},{"key":"10.1016\/j.bpa.2017.02.001_bib21","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1053\/j.semperi.2011.01.005","article-title":"The use of simulation to teach clinical skills in obstetrics","volume":"35","author":"Cass","year":"2011","journal-title":"Semin Perinatol"},{"key":"10.1016\/j.bpa.2017.02.001_bib22","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1053\/j.semperi.2013.02.004","article-title":"Moving forward in patient safety: multidisciplinary team training","volume":"37","author":"Daniels","year":"2013","journal-title":"Semin Perinatol"},{"key":"10.1016\/j.bpa.2017.02.001_bib23","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/aogs.12321","article-title":"Helping mothers survive bleeding after birth: an evaluation of simulation-based training in a low-resource setting","volume":"93","author":"Nelissen","year":"2014","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.bpa.2017.02.001_bib24","series-title":"World Health Organization recommendations for the prevention and treatment of postpartum haemorrhage","year":"2012"},{"key":"10.1016\/j.bpa.2017.02.001_bib25","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1097\/AOG.0000000000000869","article-title":"National partnership for maternal safety: consensus bundle on obstetric hemorrhage","volume":"121","author":"Main","year":"2015","journal-title":"Anesth Analg"},{"key":"10.1016\/j.bpa.2017.02.001_bib26","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1111\/anae.13489","article-title":"AAGBI guidelines: the use of blood components and their alternatives 2016","volume":"71","author":"Klein","year":"2016","journal-title":"Anaesthesia"},{"key":"10.1016\/j.bpa.2017.02.001_bib27","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1097\/EJA.0b013e32835f4d5b","article-title":"Management of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology","volume":"30","author":"Kozek-Langenecker","year":"2013","journal-title":"Eur J Anaesthesiol"},{"key":"10.1016\/j.bpa.2017.02.001_bib28","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.ejogrb.2015.12.012","article-title":"Postpartum hemorrhage: guidelines for clinical practice from the French College of Gynaecologists and Obstetricians (CNGOF) in collaboration with the French Society of Anesthesiology and Intensive Care (SFAR)","volume":"198","author":"Sentilhes","year":"2016","journal-title":"Eur J Obstet Gynecol Rep Biol"},{"key":"10.1016\/j.bpa.2017.02.001_bib29","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1213\/ANE.0000000000001473","article-title":"National and international guidelines for patient blood management in obstetrics: a qualitative review","volume":"124","author":"Shaylor","year":"2017","journal-title":"Anesth Analg"},{"key":"10.1016\/j.bpa.2017.02.001_bib30","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1097\/GRF.0000000000000062","article-title":"Obstetric hemorrhage: recent advances","volume":"57","author":"Saad","year":"2014","journal-title":"Clin Obstet Gynecol"},{"key":"10.1016\/j.bpa.2017.02.001_bib31","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1097\/ACO.0000000000000180","article-title":"Transfusion and coagulation management in major obstetric hemorrhage","volume":"28","author":"Butwick","year":"2015","journal-title":"Curr Opin Anesthesiol"},{"key":"10.1016\/j.bpa.2017.02.001_bib32","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1053\/j.semperi.2015.11.015","article-title":"Care bundles for management of obstetrical haemorrhage","volume":"40","author":"Fleischer","year":"2016","journal-title":"Semin Perinatol"},{"key":"10.1016\/j.bpa.2017.02.001_bib33","first-page":"1039","article-title":"ACOG practice bulletin: clinical management guidelines for obstetrician-Gynecologists number 76, October 2006: postpartum haemorrhage","volume":"108","author":"American College of Obstetricians and Gynecologists","year":"2006","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.bpa.2017.02.001_bib34","article-title":"Treatment for primary postpartum haemorrhage","volume":"2","author":"Mousa","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.bpa.2017.02.001_bib35","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1097\/ACO.0000000000000081","article-title":"New approaches to obstetric hemorrhage: the postpartum hemorrhage consensus algorithm","volume":"27","author":"Girard","year":"2014","journal-title":"Curr Opin Anaesthesiol"},{"key":"10.1016\/j.bpa.2017.02.001_bib36","doi-asserted-by":"crossref","first-page":"642.e1","DOI":"10.1016\/j.ajog.2015.01.008","article-title":"Second-line uterotonics and the risk of hemorrhage-related morbidity","volume":"212","author":"Butwick","year":"2015","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.bpa.2017.02.001_bib37","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/j.1447-0756.2008.00975.x","article-title":"External aortic compression device: the first aid for postpartum hemorrhage control","volume":"35","author":"Soltan","year":"2009","journal-title":"J\u00a0Obstet Gynaecol Res"},{"key":"10.1016\/j.bpa.2017.02.001_bib38","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1111\/j.1471-0528.1997.tb11471.x","article-title":"The B-Lynch surgical technique for the control of massive postpartum haemorrhage: an alternative to hysterectomy? Five cases reported","volume":"104","author":"B-Lynch","year":"1997","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.bpa.2017.02.001_bib39","first-page":"502","article-title":"Uterine compression sutures: surgical management of postpartum hemorrhage","volume":"99","author":"Hayman","year":"2002","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.bpa.2017.02.001_bib40","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s00404-016-4015-z","article-title":"Which uterine sparing technique should be used for uterine atony during cesarean section? The Bakri balloon or the B-Lynch suture?","volume":"294","author":"Kaya","year":"2016","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.bpa.2017.02.001_bib41","doi-asserted-by":"crossref","first-page":"30342","DOI":"10.1038\/srep30342","article-title":"Surgical management of postpartum haemorrhage: survey of French obstetricians","volume":"6","author":"Bouet","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.bpa.2017.02.001_bib42","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1177\/1076029615573303","article-title":"Treatment of postpartum hemorrhage with blood products in a tertiary hospital: outcomes and predictive factors associated with severe hemorrhage","volume":"22","author":"Guasch","year":"2016","journal-title":"Clin Appl Thromb Hemost"},{"key":"10.1016\/j.bpa.2017.02.001_bib43","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijoa.2016.06.001","article-title":"Interventional radiology for abnormally invasive placenta: do we need an alternative?","volume":"27","author":"Heidemann","year":"2016","journal-title":"Int J Obstet Anesth"},{"key":"10.1016\/j.bpa.2017.02.001_bib44","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.ijoa.2015.12.001","article-title":"Prophylactic abdominal aorta balloon occlusion during caesarean section: a retrospective case series","volume":"27","author":"Wei","year":"2016","journal-title":"Int J Obstet Anesth"},{"key":"10.1016\/j.bpa.2017.02.001_bib45","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S1521-6934(03)00019-1","article-title":"Haemostasis in normal and abnormal pregnancy","volume":"17","author":"O'Riordan","year":"2003","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"10.1016\/j.bpa.2017.02.001_bib46","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.ijgo.2009.01.035","article-title":"Prospective, sequential, longitudinal study of coagulation changes during pregnancy in Chinese women","volume":"105","author":"Liu","year":"2009","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1016\/j.bpa.2017.02.001_bib47","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1160\/TH09-10-0704","article-title":"Haemostatic reference intervals in pregnancy","volume":"103","author":"Szecsi","year":"2010","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.bpa.2017.02.001_bib48","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0301-2115(97)02734-6","article-title":"Coagulation and fibrinolysis changes in normal pregnancy increased levels of procoagulants and reduced levels of inhibitors during pregnancy induce a hypercoagulable state, combined with a reactive fibrinolysis","volume":"73","author":"Cerneca","year":"1997","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.bpa.2017.02.001_bib49","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1213\/ANE.0b013e31826f084d","article-title":"An observational study of the fresh frozen plasma: red blood cell ratio in postpartum hemorrhage","volume":"116","author":"Pasquier","year":"2013","journal-title":"Anesth Analg"},{"key":"10.1016\/j.bpa.2017.02.001_bib50","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.ijoa.2011.09.009","article-title":"Transfusion practice in major obstetric haemorrhage: lessons from trauma","volume":"21","author":"Saule","year":"2012","journal-title":"Int J Obstet Anesth"},{"key":"10.1016\/j.bpa.2017.02.001_bib51","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1182\/blood-2014-04-567891","article-title":"Fibrin-based clot formation as an early and rapid biomarker for progression of postpartum hemorrhage: a prospective study","volume":"124","author":"Collins","year":"2014","journal-title":"Blood"},{"key":"10.1016\/j.bpa.2017.02.001_bib52","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1111\/bjh.13864","article-title":"The haematological features and transfusion management of women who required massive transfusion for major obstetric haemorrhage in the UK: a population based study","volume":"172","author":"Green","year":"2016","journal-title":"Br J Haematol"},{"key":"10.1016\/j.bpa.2017.02.001_bib53","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1111\/j.1538-7836.2007.02297.x","article-title":"The decrease of fibrinogen is an early predictor of the severity of postpartum hemorrhage","volume":"5","author":"Charbit","year":"2007","journal-title":"J\u00a0Thromb Haemost"},{"issue":"Suppl. 1","key":"10.1016\/j.bpa.2017.02.001_bib54","doi-asserted-by":"crossref","first-page":"S32","DOI":"10.1016\/S0049-3848(13)70017-3","article-title":"Pathogenesis and management of peripartum coagulopathic calamities (disseminated intravascular coagulation and amniotic fluid embolism)","volume":"131","author":"Levi","year":"2013","journal-title":"Thromb Res"},{"key":"10.1016\/j.bpa.2017.02.001_bib55","first-page":"360","article-title":"Hemostatic factors and replacement of major blood loss with plasma-poor red cell concentrates","volume":"81","author":"Hiippala","year":"1995","journal-title":"Anesth Analg"},{"key":"10.1016\/j.bpa.2017.02.001_bib56","doi-asserted-by":"crossref","first-page":"2571","DOI":"10.1111\/j.1537-2995.2010.02752.x","article-title":"Fibrinogen estimates are influenced by methods of measurement and hemodilution with colloid plasma expanders","volume":"50","author":"Fenger-Eriksen","year":"2010","journal-title":"Transfusion"},{"key":"10.1016\/j.bpa.2017.02.001_bib57","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1097\/SLA.0000000000000267","article-title":"Hydroxyethyl starch reduces coagulation competence and increases blood loss during major surgery: results from a randomized controlled trial","volume":"259","author":"Rasmussen","year":"2014","journal-title":"Ann Surg"},{"key":"10.1016\/j.bpa.2017.02.001_bib58","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.blre.2009.04.002","article-title":"Disseminated intravascular coagulation in obstetric disorders and its acute haematological management","volume":"23","author":"Thachil","year":"2009","journal-title":"Blood Rev"},{"key":"10.1016\/j.bpa.2017.02.001_bib59","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1136\/bmj.2.5703.200","article-title":"Coagulation and fibrinolytic mechanisms during and after normal childbirth","volume":"2","author":"Bonnar","year":"1970","journal-title":"Br Med J"},{"key":"10.1016\/j.bpa.2017.02.001_bib60","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1093\/bja\/aes096","article-title":"Association between fibrinogen level and severity of postpartum haemorrhage: secondary analysis of a prospective trial","volume":"108","author":"Cortet","year":"2012","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bpa.2017.02.001_bib61","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1007\/s00134-011-2315-0","article-title":"Predictive factors of advanced interventional procedures in a multicentre severe postpartum haemorrhage study","volume":"37","author":"Gayat","year":"2011","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.bpa.2017.02.001_bib62","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.ijgo.2011.11.025","article-title":"Predictive factors for failure of pelvic arterial embolization for postpartum hemorrhage","volume":"117","author":"Poujade","year":"2012","journal-title":"Int J Obstet Gynaecol"},{"key":"10.1016\/j.bpa.2017.02.001_bib63","first-page":"S13","article-title":"Early fibrinogen as a predictor of red cell requirements during postpartum haemorrhage","volume":"21","author":"De Lloyd","year":"2012","journal-title":"Int J Obstet Anesth"},{"key":"10.1016\/j.bpa.2017.02.001_bib64","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.jss.2016.06.103","article-title":"A\u00a0comparison of initial lactate and initial base deficit as predictors of mortality after severe blunt trauma","volume":"205","author":"Gale","year":"2016","journal-title":"J\u00a0Surg Res"},{"key":"10.1016\/j.bpa.2017.02.001_bib65","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1111\/1471-0528.12531","article-title":"Transfusion policy after severe postpartum haemorrhage: a randomised non-inferiority trial","volume":"121","author":"Prick","year":"2014","journal-title":"BJOG"},{"key":"10.1016\/j.bpa.2017.02.001_bib66","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1111\/1471-0528.13224","article-title":"Prediction of escape red blood cell transfusion in expectantly managed women with acute anaemia after postpartum haemorrhage","volume":"122","author":"Prick","year":"2015","journal-title":"BJOG"},{"key":"10.1016\/j.bpa.2017.02.001_bib67","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1213\/ANE.0000000000000786","article-title":"Cell salvage in obstetrics","volume":"121","author":"Goucher","year":"2015","journal-title":"Anesth Analg"},{"key":"10.1016\/j.bpa.2017.02.001_bib68","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1097\/AOG.0000000000000729","article-title":"Red blood cell salvage during obstetric hemorrhage","volume":"125","author":"Milne","year":"2015","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.bpa.2017.02.001_bib69","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1111\/j.1365-2044.2012.07247.x","article-title":"An evaluation of the ability of leucocyte depletion filters to remove components of amniotic fluid","volume":"67","author":"Campbell","year":"2012","journal-title":"Anaesthesia"},{"key":"10.1016\/j.bpa.2017.02.001_bib70","unstructured":"National Institute for Clinical Excellence. Intraoperative blood cell salvage in obstetrics (November 2005) https:\/\/www.nice.org.uk\/guidance\/ipg144. [accessed 8 January 2017]."},{"key":"10.1016\/j.bpa.2017.02.001_bib71","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1097\/GCO.0000000000000116","article-title":"Does current evidence support the use of intraoperative cell salvage in reducing the need for blood transfusion in caesarean section?","volume":"26","author":"Dhariwal","year":"2014","journal-title":"Curr Opin Obstet Gynecol"},{"key":"10.1016\/j.bpa.2017.02.001_bib72","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.ijoa.2015.03.002","article-title":"Cell salvage for vaginal delivery \u2013 is it time we considered it?","volume":"24","author":"Wilson","year":"2015","journal-title":"Int J Obstet Anesth"},{"key":"10.1016\/j.bpa.2017.02.001_bib73","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1093\/bja\/aeu086","article-title":"Theoretical modelling of fibrinogen supplementation with therapeutic plasma, cryoprecipitate, or fibrinogen concentrate","volume":"113","author":"Collins","year":"2014","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bpa.2017.02.001_bib74","unstructured":"National Institute for Clinical Excellence. Detecting, managing and monitoring haemostasis: viscoelastometric point-of-care testing (ROTEM, TEG and Sonoclot systems) NICE guidance 2014. https:\/\/www.nice.org.uk\/guidance\/dg13. [accessed 8 January 2017]."},{"key":"10.1016\/j.bpa.2017.02.001_bib75","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1111\/bjh.13580","article-title":"British Committee for Standards in Haematology. A practical guideline for the haematological management of major haemorrhage","volume":"170","author":"Hunt","year":"2015","journal-title":"Br J Haematol"},{"key":"10.1016\/j.bpa.2017.02.001_bib76","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1111\/j.1365-3148.2012.01178.x","article-title":"The efficacy of fibrinogen concentrate compared with cryoprecipitate in major obstetric haemorrhage \u2013 an observational study","volume":"22","author":"Ahmed","year":"2012","journal-title":"Transfus Med"},{"key":"10.1016\/j.bpa.2017.02.001_bib77","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1111\/anae.13448","article-title":"Platelet count and transfusion requirements during moderate or severe postpartum haemorrhage","volume":"71","author":"Jones","year":"2016","journal-title":"Anaesthesia"},{"key":"10.1016\/j.bpa.2017.02.001_bib78","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.jemermed.2015.09.017","article-title":"Commentary on reconstituting fibrinogen concentrate to maintain blinding in a double-blind, randomized trial in an emergency setting","volume":"50","author":"Bruynseels","year":"2016","journal-title":"J\u00a0Emerg Med"},{"key":"10.1016\/j.bpa.2017.02.001_bib79","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1111\/j.1365-3148.2012.01168.x","article-title":"National audit of the use of fibrinogen concentrate to correct hypofibrinogenaemia","volume":"22","author":"Gollop","year":"2012","journal-title":"Transfus Med"},{"key":"10.1016\/j.bpa.2017.02.001_bib80","series-title":"National Institute of Clinical Excellence. Intrapartum care: care of healthy women and their babies during childbirth","author":"Kenyon","year":"2007"},{"key":"10.1016\/j.bpa.2017.02.001_bib81","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD001886.pub3","article-title":"Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion","volume":"3","author":"Henry","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.bpa.2017.02.001_bib82","first-page":"23","article-title":"Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial","volume":"376","author":"Shakur","year":"2011","journal-title":"Lancet"},{"key":"10.1016\/j.bpa.2017.02.001_bib83","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.thromres.2014.11.012","article-title":"Tranexamic acid\u2013an old drug still going strong and making a revival","volume":"135","author":"Tengborn","year":"2015","journal-title":"Thromb Res"},{"key":"10.1016\/j.bpa.2017.02.001_bib84","doi-asserted-by":"crossref","first-page":"R117","DOI":"10.1186\/cc10143","article-title":"High-dose tranexamic acid reduces blood loss in postpartum haemorrhage","volume":"15","author":"Ducloy-Bouthors","year":"2011","journal-title":"Crit Care"},{"key":"10.1016\/j.bpa.2017.02.001_bib85","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.medin.2015.05.002","article-title":"Multidisciplinary consensus document on the management of massive haemorrhage (HEMOMAS document)","volume":"39","author":"Llau","year":"2015","journal-title":"Med Intensiva"},{"key":"10.1016\/j.bpa.2017.02.001_bib86","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1093\/bja\/aes361","article-title":"Haemostatic monitoring during postpartum haemorrhage and implications for management","volume":"109","author":"Solomon","year":"2012","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bpa.2017.02.001_bib87","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta19580","article-title":"Viscoelastic point-of-care testing to assist with the diagnosis, management and monitoring of haemostasis: a systematic review and cost-effectiveness analysis","volume":"19","author":"Whiting","year":"2015","journal-title":"Health Technol Assess"},{"issue":"3","key":"10.1016\/j.bpa.2017.02.001_bib88","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD007871.pub2","article-title":"Thrombelastography (TEG) or thromboelastometry (ROTEM) to monitor haemotherapy versus usual care in patients with massive transfusion","author":"Afshari","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.bpa.2017.02.001_bib89","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1111\/j.1471-0528.2009.02187.x","article-title":"Bedside assessment of fibrinogen level in postpartum haemorrhage by thrombelastometry","volume":"116","author":"C1","year":"2009","journal-title":"BJOG"},{"key":"10.1016\/j.bpa.2017.02.001_bib90","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/anae.12859","article-title":"Introduction of an algorithm for ROTEM-guided fibrinogen concentrate administration in major obstetric haemorrhage","volume":"70","author":"Mallaiah","year":"2015","journal-title":"Anaesthesia"},{"key":"10.1016\/j.bpa.2017.02.001_bib91","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1111\/anae.13128","article-title":"A\u00a0reply","volume":"70","author":"Mallaiah","year":"2015","journal-title":"Anaesthesia"},{"key":"10.1016\/j.bpa.2017.02.001_bib92","doi-asserted-by":"crossref","first-page":"2759","DOI":"10.1182\/blood-2014-10-512608","article-title":"How I treat postpartum hemorrhage","volume":"125","author":"Pavord","year":"2015","journal-title":"Blood"},{"key":"10.1016\/j.bpa.2017.02.001_bib93","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1093\/bja\/aeu444","article-title":"FIB-PPH trial group. Pre-emptive treatment with fibrinogen concentrate for postpartum haemorrhage: randomized controlled trial","volume":"114","author":"Wikkels\u00f8","year":"2015","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.bpa.2017.02.001_bib94","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1186\/s13063-015-0670-9","article-title":"Fibrinogen concentrate versus placebo for treatment of postpartum haemorrhage: study protocol for a randomised controlled trial","volume":"16","author":"Aawar","year":"2015","journal-title":"Trials"},{"key":"10.1016\/j.bpa.2017.02.001_bib95","first-page":"S6","article-title":"Fibrinogen concentrate versus placebo for treatment of postpartum haemorrhage: a multicentre, prospective, double-blind randomised control study (OBS2)","volume":"26","author":"Bruynseels","year":"2016","journal-title":"Int J Obst Anesth"},{"issue":"Suppl. 1","key":"10.1016\/j.bpa.2017.02.001_bib96","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/anae.12913","article-title":"Haemostatic management of obstetric haemorrhage","volume":"70","author":"Collis","year":"2015","journal-title":"Anaesthesia"}],"container-title":["Best Practice & Research Clinical Anaesthesiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S152168961730006X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S152168961730006X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T07:20:17Z","timestamp":1776410417000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S152168961730006X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":96,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["S152168961730006X"],"URL":"https:\/\/doi.org\/10.1016\/j.bpa.2017.02.001","relation":{},"ISSN":["1753-3740"],"issn-type":[{"value":"1753-3740","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Managing major obstetric haemorrhage: Pharmacotherapy and transfusion","name":"articletitle","label":"Article Title"},{"value":"Best Practice & Research Clinical Anaesthesiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bpa.2017.02.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}