{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T14:15:59Z","timestamp":1791036959761,"version":"4.1.0"},"reference-count":63,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2009,4,1]],"date-time":"2009-04-01T00:00:00Z","timestamp":1238544000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Best Practice & Research Clinical Gastroenterology"],"published-print":{"date-parts":[[2009,4]]},"DOI":"10.1016\/j.bpg.2009.03.006","type":"journal-article","created":{"date-parts":[[2009,5,5]],"date-time":"2009-05-05T09:31:38Z","timestamp":1241515898000},"page":"209-218","source":"Crossref","is-referenced-by-count":58,"title":["MUTYH-associated polyposis"],"prefix":"10.1016","volume":"23","author":[{"given":"Julian R.","family":"Sampson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bpg.2009.03.006_bib1","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1038\/ng828","article-title":"Inherited variants of MYH associated with somatic G: C\u00a0\u2192\u00a0T: a mutations in colorectal tumors","volume":"30","author":"Al-Tassan","year":"2002","journal-title":"Nat Genet"},{"key":"10.1016\/j.bpg.2009.03.006_bib2","doi-asserted-by":"crossref","first-page":"2961","DOI":"10.1093\/hmg\/11.23.2961","article-title":"Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G:C\u00a0\u2192\u00a0T:A mutations","volume":"11","author":"Jones","year":"2002","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.bpg.2009.03.006_bib3","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1056\/NEJMoa025283","article-title":"Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH","volume":"348","author":"Sieber","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.bpg.2009.03.006_bib4","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0140-6736(03)13805-6","article-title":"Autosomal recessive colorectal adenomatous polyposis due to inherited mutations of MYH","volume":"362","author":"Sampson","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.bpg.2009.03.006_bib5","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.cgh.2006.01.005","article-title":"Novel findings in Swedish patients with MYH-associated polyposis: mutation detection and clinical characterization","volume":"4","author":"Kanter-Smoler","year":"2006","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.bpg.2009.03.006_bib6","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1111\/j.1399-0004.2005.00519.x","article-title":"Attenuated familial adenomatous polyposis and Muir-Torre syndrome linked to compound biallelic constitutional MYH gene mutations","volume":"68","author":"Ponti","year":"2005","journal-title":"Clin Genet"},{"key":"10.1016\/j.bpg.2009.03.006_bib7","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s10689-007-9161-9","article-title":"Sebaceous adenomas in an MYH associated polyposis patient of Indian (Gujarati) origin","volume":"7","author":"Kumar","year":"2008","journal-title":"Fam Cancer"},{"key":"10.1016\/j.bpg.2009.03.006_bib8","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1111\/j.1399-0004.2007.00900.x","article-title":"Germline mutation prevalence in the base excision repair gene, MYH, in patients with endometrial cancer","volume":"72","author":"Barnetson","year":"2007","journal-title":"Clin Genet"},{"key":"10.1016\/j.bpg.2009.03.006_bib9","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1093\/jnci\/djh288","article-title":"Association between biallelic and monoallelic germline MYH gene mutations and colorectal cancer risk","volume":"96","author":"Croitoru","year":"2004","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.bpg.2009.03.006_bib10","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1002\/ijc.20020","article-title":"Comprehensive analysis of the contribution of germline MYH variation to early-onset colorectal cancer","volume":"109","author":"Fleischmann","year":"2004","journal-title":"Int J Cancer"},{"key":"10.1016\/j.bpg.2009.03.006_bib11","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1053\/j.gastro.2004.03.070","article-title":"MYH mutations in patients with attenuated and classic polyposis and with young-onset colorectal cancer without polyps","volume":"127","author":"Wang","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bpg.2009.03.006_bib12","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1086\/431213","article-title":"Germline susceptibility to colorectal cancer due to base-excision repair gene defects","volume":"77","author":"Farrington","year":"2005","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.bpg.2009.03.006_bib13","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1038\/sj.bjc.6603239","article-title":"Association of MUTYH and colorectal cancer","volume":"95","author":"Tenesa","year":"2006","journal-title":"Br J Cancer"},{"key":"10.1016\/j.bpg.2009.03.006_bib14","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1038\/sj.bjc.6601747","article-title":"Increased frequency of the k-ras G12C mutation in MYH polyposis colorectal adenomas","volume":"90","author":"Jones","year":"2004","journal-title":"Br J Cancer"},{"key":"10.1016\/j.bpg.2009.03.006_bib15","first-page":"595","article-title":"Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway","volume":"63","author":"Lipton","year":"2003","journal-title":"Cancer Res"},{"key":"10.1016\/j.bpg.2009.03.006_bib16","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1038\/362709a0","article-title":"Instability and decay of the primary structure of DNA","volume":"362","author":"Lindahl","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.bpg.2009.03.006_bib17","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0891-5849(90)90091-V","article-title":"Free radicals and the etiology of colon cancer","volume":"8","author":"Babbs","year":"1990","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.bpg.2009.03.006_bib18","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/0027-5107(91)90157-J","article-title":"Endogenous mutagens and the causes of aging and cancer","volume":"250","author":"Ames","year":"1991","journal-title":"Mutat Res"},{"key":"10.1016\/j.bpg.2009.03.006_bib19","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1177\/153537020422900702","article-title":"Commensal bacteria, redox stress, and colorectal cancer: mechanisms and models","volume":"229","author":"Huycke","year":"2004","journal-title":"Exp Biol Med (Maywood)"},{"key":"10.1016\/j.bpg.2009.03.006_bib20","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1515\/BC.2002.098","article-title":"Exocyclic DNA adducts as oxidative stress markers in colon carcinogenesis: potential role of lipid peroxidation, dietary fat and antioxidants","volume":"383","author":"Bartsch","year":"2002","journal-title":"Biol Chem"},{"key":"10.1016\/j.bpg.2009.03.006_bib21","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1136\/gut.2007.145748","article-title":"Inherited predisposition to colorectal adenomas caused by multiple rare alleles of MUTYH but not OGG1, NUDT1, NTH1 or NEIL 1, 2 or 3","volume":"57","author":"Dallosso","year":"2008","journal-title":"Gut"},{"key":"10.1016\/j.bpg.2009.03.006_bib22","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1016\/S0002-9440(10)64288-5","article-title":"Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers","volume":"162","author":"Halford","year":"2003","journal-title":"Am J Pathol"},{"key":"10.1016\/j.bpg.2009.03.006_bib23","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/S0002-9440(10)63443-8","article-title":"Proportion and phenotype of MYH-associated colorectal neoplasia in a population-based series of Finnish colorectal cancer patients","volume":"163","author":"Enholm","year":"2003","journal-title":"Am J Pathol"},{"key":"10.1016\/j.bpg.2009.03.006_bib24","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1002\/ijc.20054","article-title":"Prevalence of the Y165C, G382D and 1395delGGA germline mutations of the MYH gene in Italian patients with adenomatous polyposis coli and colorectal adenomas","volume":"109","author":"Gismondi","year":"2004","journal-title":"Int J Cancer"},{"key":"10.1016\/j.bpg.2009.03.006_bib25","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1002\/humu.9282","article-title":"Germline MUTYH (MYH) mutations in Portuguese individuals with multiple colorectal adenomas","volume":"24","author":"Isidro","year":"2004","journal-title":"Hum Mutat"},{"key":"10.1016\/j.bpg.2009.03.006_bib26","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1002\/humu.9370","article-title":"Mutations of APC and MYH in unrelated Italian patients with adenomatous polyposis coli","volume":"26","author":"Aceto","year":"2005","journal-title":"Hum Mutat"},{"key":"10.1016\/j.bpg.2009.03.006_bib27","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1002\/humu.9224","article-title":"Molecular analysis of the APC and MYH genes in Czech families affected by FAP or multiple adenomas: 13 novel mutations","volume":"23","author":"Vandrovcov\u00e1","year":"2004","journal-title":"Hum Mutat"},{"key":"10.1016\/j.bpg.2009.03.006_bib28","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.mrfmmm.2005.01.017","article-title":"Germline mutations of the MYH gene in Japanese patients with multiple colorectal adenomas","volume":"578","author":"Miyaki","year":"2005","journal-title":"Mutat Res"},{"key":"10.1016\/j.bpg.2009.03.006_bib29","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1002\/ijc.20983","article-title":"Mutation analysis of the MYH gene in an Australian series of colorectal polyposis patients with or without germline APC mutations","volume":"116","author":"Kairupan","year":"2005","journal-title":"Int J Cancer"},{"key":"10.1016\/j.bpg.2009.03.006_bib30","doi-asserted-by":"crossref","first-page":"e54","DOI":"10.1136\/jmg.2005.033217","article-title":"Multiplicity in polyp count and extracolonic manifestations in 40 Dutch patients with MYH associated polyposis coli (MAP)","volume":"42","author":"Nielsen","year":"2005","journal-title":"J Med Genet"},{"key":"10.1016\/j.bpg.2009.03.006_bib31","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1002\/ijc.21905","article-title":"MUTYH-associated polyposis: 70 of 71 patients with biallelic mutations present with an attenuated or atypical phenotype","volume":"119","author":"Aretz","year":"2006","journal-title":"Int J Cancer"},{"key":"10.1016\/j.bpg.2009.03.006_bib32","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1053\/j.gastro.2008.10.056","article-title":"Analysis of MUTYH genotypes and colorectal phenotypes in patients with MUTYH-associated polyposis","volume":"136","author":"Nielsen","year":"2009","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bpg.2009.03.006_bib33","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.cgh.2006.12.025","article-title":"Identification of MYH mutation carriers in colorectal cancer: a multicenter, case\u2013control, population-based study","volume":"5","author":"Balaguer","year":"2007","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.bpg.2009.03.006_bib34","unstructured":"Jones N. Molecular genetic and phenotypic characteristics of patients with adenomatous colorectal polyposis. PhD Thesis, Cardiff University; 2007."},{"key":"10.1016\/j.bpg.2009.03.006_bib35","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1016\/S1542-3565(05)00411-8","article-title":"Correlation of polyp number and family history of colon cancer with germline MYH mutations","volume":"3","author":"Jo","year":"2005","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.bpg.2009.03.006_bib36","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1007\/s10350-007-9027-0","article-title":"Colorectal adenomatous polyposis associated with MYH mutations: genotype and phenotype characteristics","volume":"50","author":"Bouguen","year":"2007","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.bpg.2009.03.006_bib37","doi-asserted-by":"crossref","first-page":"1937","DOI":"10.1002\/ijc.21470","article-title":"Prevalence of MYH germline mutations in Swiss APC mutation-negative polyposis patients","volume":"118","author":"Russell","year":"2006","journal-title":"Int J Cancer"},{"key":"10.1016\/j.bpg.2009.03.006_bib38","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1038\/sj.ejhg.5201584","article-title":"Phenotypic and genotypic heterogeneity in the Lynch syndrome: diagnostic, surveillance and management implications","volume":"14","author":"Lynch","year":"2006","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.bpg.2009.03.006_bib39","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/j.1399-0004.2008.01125.x","article-title":"Cumulative lifetime incidence of extracolonic cancers in Lynch syndrome: a report of 121 families with proven mutations","volume":"75","author":"Barrow","year":"2009","journal-title":"Clin Genet"},{"key":"10.1016\/j.bpg.2009.03.006_bib40","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1136\/gut.2005.087106","article-title":"Disease severity and genetic pathways in attenuated familial adenomatous polyposis vary greatly but depend on the site of the germline mutation","volume":"55","author":"Sieber","year":"2006","journal-title":"Gut"},{"key":"10.1016\/j.bpg.2009.03.006_bib41","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1111\/j.1572-0241.2006.00375.x","article-title":"Familial adenomatous polyposis","volume":"101","author":"Galiatsatos","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.bpg.2009.03.006_bib42","doi-asserted-by":"crossref","first-page":"1822","DOI":"10.1111\/j.1572-0241.2002.05850.x","article-title":"Challenge in the differentiation between attenuated familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer: case report with review of the literature","volume":"97","author":"Cao","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.bpg.2009.03.006_bib43","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1053\/j.gastro.2007.08.019","article-title":"Development of colorectal tumours in colonoscopic surveillance in Lynch syndrome","volume":"133","author":"Mecklin","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bpg.2009.03.006_bib44","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1023\/A:1023286520725","article-title":"Attenuated familial adenomatous polyposis (AFAP). A review of the literature","volume":"2","author":"Knudsen","year":"2003","journal-title":"Fam Cancer"},{"key":"10.1016\/j.bpg.2009.03.006_bib45","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1053\/j.gastro.2006.03.046","article-title":"Hyperplastic polyposis syndrome: phenotypic presentations and the role of MBD4 and MYH","volume":"131","author":"Chow","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bpg.2009.03.006_bib46","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1002\/jso.20724","article-title":"Germline MYH mutations in a clinic-based series of Canadian multiple colorectal adenoma patients","volume":"95","author":"Croitoru","year":"2007","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.bpg.2009.03.006_bib47","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1053\/j.gastro.2008.09.020","article-title":"Hyperplastic polyps and sessile serrated adenomas as a phenotypic expression of MYH-associated polyposis","volume":"135","author":"Boparai","year":"2008","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bpg.2009.03.006_bib48","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1002\/humu.9460","article-title":"Low frequency of AXIN2 mutations and high frequency of MUTYH mutations in patients with multiple polyposis","volume":"27","author":"Lejeune","year":"2006","journal-title":"Hum Mutat"},{"key":"10.1016\/j.bpg.2009.03.006_bib49","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1089\/gte.2007.9995","article-title":"Similar colorectal cancer risk in patients with monoallelic and biallelic mutations in the MYH gene identified in a population with adenomatous polyposis","volume":"11","author":"Olschwang","year":"2007","journal-title":"Genet Test"},{"key":"10.1016\/j.bpg.2009.03.006_bib50","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1136\/jcp.2005.031757","article-title":"Duodenal carcinoma in MUTYH-associated polyposis","volume":"59","author":"Nielsen","year":"2006","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.bpg.2009.03.006_bib51","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1093\/jnci\/djm291","article-title":"The frequency of Muir-Torre syndrome among Lynch syndrome families","volume":"100","author":"South","year":"2008","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.bpg.2009.03.006_bib52","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1038\/sj.jid.5700723","article-title":"BRAF mutations in multiple sebaceous hyperplasias of patients belonging to MYH-associated polyposis pedigrees","volume":"127","author":"Ponti","year":"2007","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.bpg.2009.03.006_bib53","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.canlet.2008.09.022","article-title":"Endometrial cancer and somatic G\u00a0>\u00a0T KRAS transversion in patients with constitutional MUTYH biallelic mutations","volume":"274","author":"Tricarico","year":"2009","journal-title":"Cancer Lett"},{"key":"10.1016\/j.bpg.2009.03.006_bib54","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1093\/carcin\/bgi166","article-title":"Cells with pathogenic biallelic mutations in the human MUTYH gene are defective in DNA damage binding and repair","volume":"26","author":"Parker","year":"2005","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.bpg.2009.03.006_bib55","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1177\/000313480707301212","article-title":"Variable phenotypic expression of identical MYH germline mutations in siblings with attenuated familial adenomatous polyposis","volume":"73","author":"Raoof","year":"2007","journal-title":"Am Surg"},{"key":"10.1016\/j.bpg.2009.03.006_bib56","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1136\/gut.51.3.420","article-title":"Explaining variation in familial adenomatous polyposis: relationship between genotype and phenotype and evidence for modifier genes","volume":"51","author":"Crabtree","year":"2002","journal-title":"Gut"},{"key":"10.1016\/j.bpg.2009.03.006_bib57","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/gcc.20011","article-title":"Role of inherited defects of MYH in the development of sporadic colorectal cancer","volume":"40","author":"Kambara","year":"2004","journal-title":"Genes Chromosomes Cancer"},{"key":"10.1016\/j.bpg.2009.03.006_bib58","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1086\/507912","article-title":"Colorectal cancer risk in monoallelic carriers of MYH variants","volume":"79","author":"Webb","year":"2006","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.bpg.2009.03.006_bib59","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1089\/gte.2005.9.147","article-title":"Germline mutations in the MYH gene in Swedish familial and sporadic colorectal cancer","volume":"9","author":"Zhou","year":"2005","journal-title":"Genet Test"},{"key":"10.1016\/j.bpg.2009.03.006_bib60","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1089\/gte.2007.0029","article-title":"The thorough screening of the MUTYH gene in a large French cohort of sporadic colorectal cancers","volume":"11","author":"K\u00fcry","year":"2007","journal-title":"Genet Test"},{"key":"10.1016\/j.bpg.2009.03.006_bib61","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1002\/ijc.20767","article-title":"Colorectal cancer risk in individuals with biallelic or monoallelic mutations of MYH","volume":"114","author":"Peterlongo","year":"2005","journal-title":"Int J Cancer"},{"key":"10.1016\/j.bpg.2009.03.006_bib62","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1111\/j.1399-0004.2007.00766.x","article-title":"Germline mutations in APC and MUTYH are responsible for the majority of families with attenuated familial adenomatous polyposis","volume":"71","author":"Nielsen","year":"2007","journal-title":"Clin Genet"},{"key":"10.1016\/j.bpg.2009.03.006_bib63","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1136\/gut.2007.136127","article-title":"Guidelines for the clinical management of familial adenomatous polyposis (FAP)","volume":"57","author":"Vasen","year":"2008","journal-title":"Gut"}],"container-title":["Best Practice & Research Clinical Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521691809000444?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521691809000444?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,4]],"date-time":"2021-10-04T23:40:40Z","timestamp":1633390840000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521691809000444"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4]]},"references-count":63,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,4]]}},"alternative-id":["S1521691809000444"],"URL":"https:\/\/doi.org\/10.1016\/j.bpg.2009.03.006","relation":{},"ISSN":["1521-6918"],"issn-type":[{"value":"1521-6918","type":"print"}],"subject":[],"published":{"date-parts":[[2009,4]]}}}