{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T02:28:56Z","timestamp":1789698536252,"version":"4.0.1"},"reference-count":52,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2010,12,1]],"date-time":"2010-12-01T00:00:00Z","timestamp":1291161600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Best Practice & Research Clinical Gastroenterology"],"published-print":{"date-parts":[[2010,12]]},"DOI":"10.1016\/j.bpg.2010.09.005","type":"journal-article","created":{"date-parts":[[2010,12,1]],"date-time":"2010-12-01T04:49:35Z","timestamp":1291178975000},"page":"775-786","source":"Crossref","is-referenced-by-count":13,"title":["Endoscopy in gastro-oesophageal reflux disease"],"prefix":"10.1016","volume":"24","author":[{"given":"Jan G.","family":"Hatlebakk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bpg.2010.09.005_bib1","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.1111\/j.1572-0241.2006.00630.x","article-title":"The Montreal definition and classification of gastro-ooesophageal reflux disease: a global evidence-based consensus","volume":"101","author":"Vakil","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.bpg.2010.09.005_bib2","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1111\/j.1572-0241.2002.05902.x","article-title":"Hiatal hernia size, Barrett\u2019s length, and severity of acid reflux are all risk factors for esophageal adenocarcinoma","volume":"97","author":"Avidan","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.bpg.2010.09.005_bib3","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1136\/gut.2009.200063","article-title":"Accuracy of the diagnosis of GORD by questionnaire, physicians and a trial of proton pump inhibitor treatment: the Diamond Study","volume":"59","author":"Dent","year":"2010","journal-title":"Gut"},{"key":"10.1016\/j.bpg.2010.09.005_bib4","doi-asserted-by":"crossref","first-page":"2777","DOI":"10.1185\/03007990903314546","article-title":"Management of gastro-oesophageal reflux disease in primary care: a European observational study","volume":"25","author":"Gisbert","year":"2009","journal-title":"Curr Med Res Opin"},{"key":"10.1016\/j.bpg.2010.09.005_bib5","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1136\/bmj.319.7209.550","article-title":"Heartburn treatment in primary care: randomised, double blind study for 8 weeks","volume":"319","author":"Hatlebakk","year":"1999","journal-title":"Br Med J"},{"key":"10.1016\/j.bpg.2010.09.005_bib6","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1053\/j.gastro.2004.04.010","article-title":"A critical review of the diagnosis and management of Barrett\u2019s esophagus: the AGA Chicago workshop","volume":"127","author":"Sharma","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bpg.2010.09.005_bib7","doi-asserted-by":"crossref","first-page":"176","DOI":"10.7326\/0003-4819-138-3-200302040-00009","article-title":"Screening and surveillance for Barrett\u2019s esophagus in high-risk groups: a cost-utility analysis","volume":"138","author":"Inadomi","year":"2003","journal-title":"Ann Int Med"},{"key":"10.1016\/j.bpg.2010.09.005_bib8","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/1477-7525-7-60","article-title":"Impact of gastroesophageal reflux disease on patients\u2019 daily lives: a European observational study in the primary care setting","volume":"7","author":"Gisbert","year":"2009","journal-title":"Health Qual Life Outcome"},{"key":"10.1016\/j.bpg.2010.09.005_bib9","first-page":"29","article-title":"How satisfied are chronic heartburn sufferers with their prescription medications? Results of the patient unmet needs survey","volume":"7","author":"Crawley","year":"2000","journal-title":"J Clin Outcomes Manag"},{"key":"10.1016\/j.bpg.2010.09.005_bib10","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1053\/gast.2001.24840","article-title":"Simultaneous intraesophageal impedance and pH measurement of acid and nonacid reflux: effect of omeprazole","volume":"120","author":"Vela","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bpg.2010.09.005_bib11","first-page":"1398","article-title":"Acid and non-acid reflux in patients with persistent symptoms despite acid suppressive therapy: a multicentre study using combined ambulatory impedance pH-monitoring","volume":"55","author":"Mainie","year":"2006","journal-title":"Gur"},{"key":"10.1016\/j.bpg.2010.09.005_bib12","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/S0889-8553(05)70093-5","article-title":"Medical therapy: management of the refractory patient","volume":"28","author":"Hatlebakk","year":"1999","journal-title":"Gastroenterol Clin North Am"},{"key":"10.1016\/j.bpg.2010.09.005_bib13","doi-asserted-by":"crossref","first-page":"119","DOI":"10.3109\/00365529309096057","article-title":"Interobserver variation in the endoscopic diagnosis of reflux esophagitis","volume":"28","author":"Bytzer","year":"1993","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.bpg.2010.09.005_bib14","series-title":"The esophagus","article-title":"Endoscopy of the esophagus","author":"Miller","year":"1995"},{"key":"10.1016\/j.bpg.2010.09.005_bib15","doi-asserted-by":"crossref","first-page":"760","DOI":"10.3109\/00365529708996531","article-title":"Endoscopic grading of reflux oesophagitis: what observations correlate with gastro-oesophageal reflux?","volume":"32","author":"Hatlebakk","year":"1997","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.bpg.2010.09.005_bib16","first-page":"A36","article-title":"Serious complications - stenosis, ulcer and Barrett\u2019s epithelium - develop in 21.6% of adults with erosive reflux esophagitis","volume":"100","author":"Brossard","year":"1991","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bpg.2010.09.005_bib17","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1016\/j.gie.2008.07.024","article-title":"Risk factors for detection Barrett\u2019s esophagus patients erosive esophagitis","volume":"69","author":"Modiano","year":"2009","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2010.09.005_bib18","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1136\/gut.45.2.172","article-title":"Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification","volume":"45","author":"Lundell","year":"1999","journal-title":"Gut"},{"key":"10.1016\/j.bpg.2010.09.005_bib19","series-title":"Barrett\u2019s esophagus","article-title":"Endoscopic classification of gastro-esophageal reflux disease","author":"Hatlebakk","year":"2001"},{"key":"10.1016\/j.bpg.2010.09.005_bib20","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1053\/j.gastro.2006.08.032","article-title":"The development and validation of an endoscopic grading system for Barrett\u2019s esophagus: the Prague C & M criteria","volume":"131","author":"Sharma","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bpg.2010.09.005_bib21","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1111\/j.1572-0241.2008.01835.x","article-title":"Updated guidelines 2008 for the diagnosis, surveillance and therapy of Barrett\u2019s esophagus","volume":"103","author":"Wang","year":"2008","journal-title":"Am J\u00a0Gastroenterol"},{"key":"10.1016\/j.bpg.2010.09.005_bib22","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1111\/j.1365-2036.2009.04142.x","article-title":"Development of the GerdQ, a tool for the diagnosis and management of gastro-oesophageal reflux disease in primary care","volume":"30","author":"Jones","year":"2009","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.bpg.2010.09.005_bib23","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1056\/NEJM199903183401101","article-title":"Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma","volume":"340","author":"Lagergren","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.bpg.2010.09.005_bib24","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1136\/gut.2008.148833","article-title":"Comparing laparoscopic antireflux surgery with esomeprazole in the management of patients with esomeprazole in the management of patients with chronic gastro-oesophageal reflux disease: a 3-year interim analysis of the LOTUS trial","volume":"57","author":"Lundell","year":"2008","journal-title":"Gut"},{"key":"10.1016\/j.bpg.2010.09.005_bib25","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1111\/j.1572-0241.2002.05532.x","article-title":"Esomeprazole (40\u00a0mg) compared with lansoprazole (30\u00a0mg) in the treatment of erosive esophagitis","volume":"97","author":"Castell","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.bpg.2010.09.005_bib26","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1159\/000080323","article-title":"Minimal change esophagitis: prospective comparison of endoscopic and histological markers between patients with non-erosive reflux disease and normal controls using magnification endoscopy","volume":"22","author":"Kiesslich","year":"2004","journal-title":"Dig Dis"},{"key":"10.1016\/j.bpg.2010.09.005_bib27","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1055\/s-2006-945112","article-title":"Magnification endoscopy for diagnosis of nonerosive reflux disease: a proposal of diagnostic criteria and critical analysis of observer variability","volume":"39","author":"Edebo","year":"2007","journal-title":"Endoscopy"},{"key":"10.1016\/j.bpg.2010.09.005_bib28","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1111\/j.1572-0241.2007.01731.x","article-title":"Screening for esophagitis and Barrett\u2019s esophagus with wireless esophageal capsule endoscopy: a multicenter prospective trial in patients with reflux symptoms","volume":"103","author":"Galmiche","year":"2008","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.bpg.2010.09.005_bib29","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1067\/mge.2002.123420","article-title":"Classification of Barrett\u2019s epithelium by magnifying endoscopy","volume":"55","author":"Endo","year":"2002","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2010.09.005_bib30","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/S0016-5107(03)02508-2","article-title":"Endoscopic classification of Barrett\u2019s esophagus","volume":"59","author":"Guelrud","year":"2004","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2010.09.005_bib31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.gie.2005.09.031","article-title":"Acetic acid-guided biopsies after magnifying endoscopy compared with random biopsies in the detection of Barrett\u2019s esophagus: a prospective randomized trial with crossover design","volume":"64","author":"Hoffman","year":"2006","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2010.09.005_bib32","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1055\/s-2006-944974","article-title":"Non-biopsy detection of intestinal metaplasia and dysplasia in Barrett\u2019s oesophagus: a prospective multicenter study","volume":"38","author":"Sharma","year":"2006","journal-title":"Endoscopy"},{"key":"10.1016\/j.bpg.2010.09.005_bib33","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.gie.2005.10.044","article-title":"The utility of a narrow band imaging endoscopy system in patients with Barrett\u2019s esophagus","volume":"64","author":"Sharma","year":"2006","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2010.09.005_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.cgh.2008.08.030","article-title":"The utility of narrow band imaging in improving the endoscopic diagnose of gastroesophageal reflux disease","author":"Fock","year":"2009","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.bpg.2010.09.005_bib35","doi-asserted-by":"crossref","first-page":"AB201","DOI":"10.1016\/j.gie.2010.03.361","article-title":"I-Scan is as effective as acetic acid guided chromoendoscopy and superior to random biopsies diagnosing Barrett\u2019s epithelium \u2013 a prospective randomized trial","volume":"71","author":"Hoffman","year":"2010","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2010.09.005_bib36","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1097\/MEG.0b013e3283271e87","article-title":"Zooming in on Barrett\u2019s oesophagus using narrow-band imaging: an international observer agreement study","volume":"21","author":"Herrero","year":"2009","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.bpg.2010.09.005_bib37","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/S0016-5107(00)70450-0","article-title":"High-resolution endoscopic imaging of the GI tract using optical coherence tomography","volume":"51","author":"Sivak","year":"2000","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2010.09.005_bib38","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.giec.2005.08.010","article-title":"Confocal laser endomicroscopy","volume":"15","author":"Kiesslich","year":"2005","journal-title":"Gastrointest Endosc Clin N Am"},{"key":"10.1016\/j.bpg.2010.09.005_bib39","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1016\/j.cgh.2007.05.019","article-title":"In vivo histopathology for detection of gastrointestinal neoplasia with a portable, confocal miniprobe: an examiner blinded analysis","volume":"5","author":"Meining","year":"2007","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.bpg.2010.09.005_bib40","series-title":"Atlas of endomicroscopy","article-title":"Barrett\u2019s oesophagus","author":"Kiesslich","year":"2008"},{"key":"10.1016\/j.bpg.2010.09.005_bib41","doi-asserted-by":"crossref","first-page":"AB351","DOI":"10.1016\/j.gie.2010.03.941","article-title":"Confocal endomicroscopy for the diagnosis of ultrastructural changes in non-erosive reflux disease","volume":"71","author":"Goetz","year":"2010","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2010.09.005_bib42","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/j.cgh.2006.05.010","article-title":"In vivo histology of Barrett\u2019s oesophagus and associated neoplasias by confocal laser endomicroscopy","volume":"8","author":"Kiesslich","year":"2006","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.bpg.2010.09.005_bib43","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.cgh.2006.08.006","article-title":"Microscopic esophageal mucosal injury in nonerosive reflux disease","volume":"5","author":"Dent","year":"2007","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.bpg.2010.09.005_bib44","series-title":"The esophagus","article-title":"Role of histology and cytology in esophageal disease","author":"Geisinger","year":"1999"},{"key":"10.1016\/j.bpg.2010.09.005_bib45","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0016-5085(70)80004-X","article-title":"Histological consequences of gastroesophageal reflux in man","volume":"58","author":"Ismail-Beigi","year":"1970","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bpg.2010.09.005_bib46","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1053\/gast.1996.v111.pm8898633","article-title":"Dilated intercellular spaces: a morphological feature of acid reflux-damaged human esophageal epithelium","volume":"111","author":"Tobey","year":"1996","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bpg.2010.09.005_bib47","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s004280050032","article-title":"Altered intercellular glycoconjugates and dilated intercellular spaces of esophageal epithelium in reflux disease","volume":"436","author":"Solcia","year":"2000","journal-title":"Virchows Arch"},{"key":"10.1016\/j.bpg.2010.09.005_bib48","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1159\/000007730","article-title":"Gastroesophageal reflux disease: prevalence, clinical, endoscopic and histopathological findings in 1,128 consecutive patients referred for endoscopy due to dyspeptic and reflux symptoms","volume":"61","author":"Voutilainen","year":"2000","journal-title":"Digestion"},{"key":"10.1016\/j.bpg.2010.09.005_bib49","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1046\/j.1365-2036.2003.01713.x","article-title":"Dilated intercellular spaces as a marker of oesophageal damage in gastro-oesophageal reflux disease with or without bile reflux","volume":"18","author":"Calabrese","year":"2003","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.bpg.2010.09.005_bib50","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1159\/000080319","article-title":"What parameters are relevant for the histological diagnosis of gastroesophageal reflux disease without Barrett\u2019s metaplasia?","volume":"22","author":"Vieth","year":"2004","journal-title":"Dig Dis"},{"key":"10.1016\/j.bpg.2010.09.005_bib51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1572-0241.2005.50209.x","article-title":"Reassessment of the diagnostic value of histology in patients with GORD, using multiple biopsy sites and an appropriate control group","volume":"100","author":"Zentilin","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.bpg.2010.09.005_bib52","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1038\/ajg.2009.631","article-title":"Long-term outcome of microscopic esophagitis in chronic GORD patients treated with esomeprazole or laparoscopic antireflux surgery in the LOTUS trial","volume":"105","author":"Fiocca","year":"2010","journal-title":"Am J Gastroenterol"}],"container-title":["Best Practice & Research Clinical Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521691810001149?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521691810001149?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,6]],"date-time":"2019-06-06T14:21:29Z","timestamp":1559830889000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521691810001149"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,12]]},"references-count":52,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["S1521691810001149"],"URL":"https:\/\/doi.org\/10.1016\/j.bpg.2010.09.005","relation":{},"ISSN":["1521-6918"],"issn-type":[{"value":"1521-6918","type":"print"}],"subject":[],"published":{"date-parts":[[2010,12]]}}}