{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T20:27:13Z","timestamp":1792441633948,"version":"4.5.0"},"reference-count":88,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["bpgastro.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Best Practice & Research Clinical Gastroenterology"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1016\/j.bpg.2014.10.001","type":"journal-article","created":{"date-parts":[[2014,10,9]],"date-time":"2014-10-09T18:57:41Z","timestamp":1412881061000},"page":"967-979","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":59,"title":["The stomach\u2013brain axis"],"prefix":"10.1016","volume":"28","author":[{"given":"Gerald","family":"Holtmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas J.","family":"Talley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"12 Suppl.","key":"10.1016\/j.bpg.2014.10.001_bib1","doi-asserted-by":"crossref","first-page":"18S","DOI":"10.1007\/BF02300362","article-title":"Control of gastric emptying by gastric tone","volume":"39","author":"Azpiroz","year":"1994","journal-title":"Dig Dis Sci"},{"issue":"9 Suppl. 5","key":"10.1016\/j.bpg.2014.10.001_bib2","first-page":"S11","article-title":"Physiological regulation of gastric emptying and glucose absorption","volume":"13","author":"Macdonald","year":"1996","journal-title":"Diabet Med"},{"issue":"3","key":"10.1016\/j.bpg.2014.10.001_bib3","first-page":"R408","article-title":"Postpyloric regulation of gastric emptying in rhesus monkeys","volume":"243","author":"McHugh","year":"1982","journal-title":"Am J Physiol"},{"issue":"5","key":"10.1016\/j.bpg.2014.10.001_bib4","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1111\/j.1440-1746.1989.tb01741.x","article-title":"Motor mechanisms associated with slowing of the gastric emptying of a solid meal by an intraduodenal lipid infusion","volume":"4","author":"Heddle","year":"1989","journal-title":"J Gastroenterol Hepatol"},{"issue":"12","key":"10.1016\/j.bpg.2014.10.001_bib5","doi-asserted-by":"crossref","first-page":"2673","DOI":"10.1007\/BF02220459","article-title":"Perception of gastric distension. Influence of mode of distension on perception thresholds and gastric compliance","volume":"40","author":"Holtmann","year":"1995","journal-title":"Dig Dis Sci"},{"issue":"3","key":"10.1016\/j.bpg.2014.10.001_bib6","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1136\/gut.47.3.332","article-title":"Differences in gastric mechanosensory function after repeated ramp distensions in non-consulters with dyspepsia and healthy controls","volume":"47","author":"Holtmann","year":"2000","journal-title":"Gut"},{"issue":"2","key":"10.1016\/j.bpg.2014.10.001_bib7","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S0031-9384(99)00069-4","article-title":"Comparison of the effects of a high-fat and high-carbohydrate soup delivered orally and intragastrically on gastric emptying, appetite, and eating behaviour","volume":"67","author":"Cecil","year":"1999","journal-title":"Physiol Behav"},{"issue":"1","key":"10.1016\/j.bpg.2014.10.001_bib8","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1136\/gut.2004.062869","article-title":"Selective effects of nutrients on gut sensitivity and reflexes","volume":"56","author":"Caldarella","year":"2007","journal-title":"Gut"},{"issue":"3","key":"10.1016\/j.bpg.2014.10.001_bib9","doi-asserted-by":"crossref","first-page":"838S","DOI":"10.3945\/ajcn.2009.27462W","article-title":"Protein, amino acids, vagus nerve signaling, and the brain","volume":"90","author":"Tome","year":"2009","journal-title":"Am J Clin Nutr"},{"issue":"2","key":"10.1016\/j.bpg.2014.10.001_bib10","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/0016-5085(92)90825-J","article-title":"Cephalic stimulation of gastrointestinal secretory and motor responses in humans","volume":"103","author":"Katschinski","year":"1992","journal-title":"Gastroenterology"},{"issue":"6","key":"10.1016\/j.bpg.2014.10.001_bib11","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1210\/jcem-55-6-1114","article-title":"Effect of cephalic-vagal stimulation on insulin, gastric inhibitory polypeptide, and pancreatic polypeptide release in humans","volume":"55","author":"Taylor","year":"1982","journal-title":"J\u00a0Clin Endocrinol Metab"},{"issue":"10","key":"10.1016\/j.bpg.2014.10.001_bib12","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1136\/gut.20.10.875","article-title":"Cephalic phase of gastric secretion in healthy subjects and duodenal ulcer patients: role of vagal innervation","volume":"20","author":"Konturek","year":"1979","journal-title":"Gut"},{"issue":"6","key":"10.1016\/j.bpg.2014.10.001_bib13","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1111\/j.1440-1746.2010.06269.x","article-title":"Association between clinical manifestations of complicated and uncomplicated peptic ulcer and visceral sensory dysfunction","volume":"25","author":"Gururatsakul","year":"2010","journal-title":"J Gastroenterol Hepatol"},{"issue":"5","key":"10.1016\/j.bpg.2014.10.001_bib14","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1053\/gast.2002.36556","article-title":"Do changes in visceral sensory function determine the development of dyspepsia during treatment with aspirin?","volume":"123","author":"Holtmann","year":"2002","journal-title":"Gastroenterology"},{"issue":"7","key":"10.1016\/j.bpg.2014.10.001_bib15","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1007\/BF02088548","article-title":"Association between H. pylori, duodenal mechanosensory thresholds, and small intestinal motility in chronic unexplained dyspepsia","volume":"41","author":"Holtmann","year":"1996","journal-title":"Dig Dis Sci"},{"issue":"2","key":"10.1016\/j.bpg.2014.10.001_bib16","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.neuroimage.2006.07.033","article-title":"Gastric fundic distension activates fronto-limbic structures but not primary somatosensory cortex: a functional magnetic resonance imaging study","volume":"34","author":"Ladabaum","year":"2007","journal-title":"Neuroimage"},{"key":"10.1016\/j.bpg.2014.10.001_bib17","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.neuroscience.2011.01.051","article-title":"Gastric distention induced functional magnetic resonance signal changes in the rodent brain","volume":"179","author":"Min","year":"2011","journal-title":"Neuroscience"},{"issue":"4","key":"10.1016\/j.bpg.2014.10.001_bib18","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1038\/ajg.2010.39","article-title":"Abnormal regional brain activity during rest and (anticipated) gastric distension in functional dyspepsia and the role of anxiety: a H(2)(15)O-PET study","volume":"105","author":"Van Oudenhove","year":"2010","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.bpg.2014.10.001_bib19","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.appet.2013.07.002","article-title":"Neuroimaging of gastric distension and gastric bypass surgery","volume":"71","author":"Geliebter","year":"2013","journal-title":"Appetite"},{"issue":"5900","key":"10.1016\/j.bpg.2014.10.001_bib20","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1126\/science.1161550","article-title":"Relation between obesity and blunted striatal response to food is moderated by TaqIA A1 allele","volume":"322","author":"Stice","year":"2008","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.bpg.2014.10.001_bib21","doi-asserted-by":"crossref","DOI":"10.1111\/j.1365-2982.2010.01642.x","article-title":"Different regional brain activity during physiological gastric distension compared to balloon distension: a H2 15O-PET study","volume":"23","author":"Geeraerts","year":"2011","journal-title":"Neurogastroenterol Motil"},{"issue":"3","key":"10.1016\/j.bpg.2014.10.001_bib22","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/j.1748-1716.2010.02219.x","article-title":"Plasticity in vagal afferent neurones during feeding and fasting: mechanisms and significance","volume":"201","author":"Dockray","year":"2011","journal-title":"Acta Physiol (Oxf)"},{"key":"10.1016\/j.bpg.2014.10.001_bib23","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1196\/annals.1296.008","article-title":"Integration of systemic and visceral sensory information by medullary catecholaminergic systems during peripheral inflammation","volume":"1018","author":"Hollis","year":"2004","journal-title":"Ann N Y Acad Sci"},{"issue":"6","key":"10.1016\/j.bpg.2014.10.001_bib24","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/S1091-255X(03)00071-4","article-title":"Functional neuroimaging of gastric distention","volume":"7","author":"Stephan","year":"2003","journal-title":"J Gastrointest Surg"},{"issue":"1","key":"10.1016\/j.bpg.2014.10.001_bib25","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1002\/cne.10120","article-title":"Visceral region in the rat primary somatosensory cortex identified by vagal evoked potential","volume":"444","author":"Ito","year":"2002","journal-title":"J\u00a0Comp Neurol"},{"issue":"21","key":"10.1016\/j.bpg.2014.10.001_bib26","doi-asserted-by":"crossref","first-page":"7067","DOI":"10.1523\/JNEUROSCI.0252-14.2014","article-title":"Gut vagal afferents differentially modulate innate anxiety and learned fear","volume":"34","author":"Klarer","year":"2014","journal-title":"J Neurosci"},{"issue":"4","key":"10.1016\/j.bpg.2014.10.001_bib27","doi-asserted-by":"crossref","first-page":"1824","DOI":"10.1016\/j.neuroimage.2007.11.008","article-title":"Gastric distention activates satiety circuitry in the human brain","volume":"39","author":"Wang","year":"2008","journal-title":"Neuroimage"},{"issue":"2","key":"10.1016\/j.bpg.2014.10.001_bib28","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1677\/joe.0.1800273","article-title":"Vagal stimulation exaggerates the inhibitory ghrelin response to oral fat in humans","volume":"180","author":"Heath","year":"2004","journal-title":"J Endocrinol"},{"issue":"11","key":"10.1016\/j.bpg.2014.10.001_bib29","doi-asserted-by":"crossref","first-page":"2248","DOI":"10.1016\/j.peptides.2011.05.014","article-title":"Central mechanisms involved in the orexigenic actions of ghrelin","volume":"32","author":"Andrews","year":"2011","journal-title":"Peptides"},{"issue":"4","key":"10.1016\/j.bpg.2014.10.001_bib30","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1006\/frne.1994.1012","article-title":"The area postrema and vomiting","volume":"15","author":"Miller","year":"1994","journal-title":"Front Neuroendocrinol"},{"issue":"5","key":"10.1016\/j.bpg.2014.10.001_bib31","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1053\/j.gastro.2007.03.037","article-title":"Regional cerebral blood flow during gastric balloon distention in functional dyspepsia","volume":"132","author":"Vandenberghe","year":"2007","journal-title":"Gastroenterology"},{"issue":"7","key":"10.1016\/j.bpg.2014.10.001_bib32","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1111\/nmo.12362","article-title":"Antiemesis effect and brain fMRI response of gastric electrical stimulation with different parameters in dogs","volume":"26","author":"Yu","year":"2014","journal-title":"Neurogastroenterol Motil"},{"issue":"2","key":"10.1016\/j.bpg.2014.10.001_bib33","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.nlm.2006.09.004","article-title":"Involvement of the rostral anterior cingulate cortex in consolidation of inhibitory avoidance memory: interaction with the basolateral amygdala","volume":"87","author":"Malin","year":"2007","journal-title":"Neurobiol Learn Mem"},{"issue":"3","key":"10.1016\/j.bpg.2014.10.001_bib34","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1002\/cne.10978","article-title":"Rostral agranular insular cortex and pain areas of the central nervous system: a tract-tracing study in the rat","volume":"468","author":"Jasmin","year":"2004","journal-title":"J Comp Neurol"},{"issue":"Pt 9","key":"10.1016\/j.bpg.2014.10.001_bib35","doi-asserted-by":"crossref","first-page":"2532","DOI":"10.1093\/brain\/awu183","article-title":"Impact of brain tumour location on emotion and personality: a voxel-based lesion-symptom mapping study on mentalization processes","volume":"137","author":"Campanella","year":"2014","journal-title":"Brain"},{"issue":"10","key":"10.1016\/j.bpg.2014.10.001_bib36","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1248\/bpb.31.1827","article-title":"Brain activation by umami substances via gustatory and visceral signaling pathways, and physiological significance","volume":"31","author":"Kondoh","year":"2008","journal-title":"Biol Pharm Bull"},{"issue":"3","key":"10.1016\/j.bpg.2014.10.001_bib37","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1002\/brb3.226","article-title":"Candidate gene associations with mood disorder, cognitive vulnerability, and fronto-limbic volumes","volume":"4","author":"Frazier","year":"2014","journal-title":"Brain Behav"},{"issue":"3","key":"10.1016\/j.bpg.2014.10.001_bib38","doi-asserted-by":"crossref","DOI":"10.1111\/j.1365-2982.2009.01415.x","article-title":"Is there any association between disturbed gastrointestinal visceromotor and sensory function and impaired quality of life in functional dyspepsia?","volume":"22","author":"Haag","year":"2010","journal-title":"Neurogastroenterol Motil"},{"issue":"9","key":"10.1016\/j.bpg.2014.10.001_bib39","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1136\/gutjnl-2011-300474","article-title":"The brain\u2013gut pathway in functional gastrointestinal disorders is bidirectional: a 12-year prospective population-based study","volume":"61","author":"Koloski","year":"2012","journal-title":"Gut"},{"issue":"5","key":"10.1016\/j.bpg.2014.10.001_bib40","doi-asserted-by":"crossref","first-page":"G850","DOI":"10.1152\/ajpgi.2001.280.5.G850","article-title":"Modulation of gastric motor activity by a centrally acting stimulus, circular vection, in humans","volume":"280","author":"Faas","year":"2001","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"issue":"4","key":"10.1016\/j.bpg.2014.10.001_bib41","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/j.1365-2982.1991.tb00068.x","article-title":"Stress and gastrointestinal motility in humans: a review of the literature","volume":"3","author":"Holtmann","year":"1991","journal-title":"Neurogastroenterol Motil"},{"issue":"7","key":"10.1016\/j.bpg.2014.10.001_bib42","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1177\/070674378803300715","article-title":"Beaumont's contribution to gastric psychophysiology: a reappraisal","volume":"33","author":"Mai","year":"1988","journal-title":"Can J Psychiatry"},{"issue":"11","key":"10.1016\/j.bpg.2014.10.001_bib43","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1007\/BF01540047","article-title":"Differential effects of acute mental stress on interdigestive secretion of gastric acid, pancreatic enzymes, and gastroduodenal motility","volume":"34","author":"Holtmann","year":"1989","journal-title":"Dig Dis Sci"},{"issue":"8","key":"10.1016\/j.bpg.2014.10.001_bib44","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1007\/BF01537249","article-title":"Mental stress and gastric acid secretion. Do personality traits influence the response?","volume":"35","author":"Holtmann","year":"1990","journal-title":"Dig Dis Sci"},{"issue":"1","key":"10.1016\/j.bpg.2014.10.001_bib45","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0016-5085(94)90061-2","article-title":"Relaxation training reduces symptom reports and acid exposure in patients with gastroesophageal reflux disease","volume":"107","author":"McDonald-Haile","year":"1994","journal-title":"Gastroenterology"},{"issue":"11","key":"10.1016\/j.bpg.2014.10.001_bib46","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1136\/gutjnl-2012-302634","article-title":"A multidimensional model of psychobiological interactions in functional dyspepsia: a structural equation modelling approach","volume":"62","author":"Jones","year":"2013","journal-title":"Gut"},{"issue":"4","key":"10.1016\/j.bpg.2014.10.001_bib47","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1111\/j.1572-0241.2001.03605.x","article-title":"Psychological distress is linked to gastrointestinal symptoms in diabetes mellitus","volume":"96","author":"Talley","year":"2001","journal-title":"Am J Gastroenterol"},{"issue":"12","key":"10.1016\/j.bpg.2014.10.001_bib48","doi-asserted-by":"crossref","DOI":"10.1111\/j.1365-2982.2012.01985.x","article-title":"Associations between gastric sensorimotor function, depression, somatization, and symptom-based subgroups in functional gastroduodenal disorders: are all symptoms equal?","volume":"24","author":"Clauwaert","year":"2012","journal-title":"Neurogastroenterol Motil"},{"issue":"6","key":"10.1016\/j.bpg.2014.10.001_bib49","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1016\/0016-5085(89)90502-7","article-title":"Modulation of gastric acid secretion by hypnosis","volume":"96","author":"Klein","year":"1989","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.bpg.2014.10.001_bib50","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1097\/00004836-199309000-00006","article-title":"The effect of acute emotional stress on gastric acid secretion in normal subjects and duodenal ulcer patients","volume":"17","author":"Bresnick","year":"1993","journal-title":"J Clin Gastroenterol"},{"issue":"6","key":"10.1016\/j.bpg.2014.10.001_bib51","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1097\/MOG.0b013e328365efc7","article-title":"Gastric secretion","volume":"29","author":"Chu","year":"2013","journal-title":"Curr Opin Gastroenterol"},{"issue":"6","key":"10.1016\/j.bpg.2014.10.001_bib52","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1097\/MOG.0b013e328331b62a","article-title":"Gastric exocrine and endocrine secretion","volume":"25","author":"Schubert","year":"2009","journal-title":"Curr Opin Gastroenterol"},{"issue":"1","key":"10.1016\/j.bpg.2014.10.001_bib53","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/j.1399-6576.1998.tb05088.x","article-title":"Propofol sedation and gastric emptying in volunteers","volume":"42","author":"Hammas","year":"1998","journal-title":"Acta Anaesthesiol Scand"},{"issue":"8","key":"10.1016\/j.bpg.2014.10.001_bib54","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1111\/j.1365-2044.1994.tb04395.x","article-title":"A\u00a0comparison of the effect on gastric emptying of either enflurane or propofol given during maintenance of anaesthesia for minor surgery","volume":"49","author":"Bennett","year":"1994","journal-title":"Anaesthesia"},{"issue":"4 Pt 1","key":"10.1016\/j.bpg.2014.10.001_bib55","first-page":"G767","article-title":"Effects of gastric pacing on canine gastric motility and emptying","volume":"265","author":"Eagon","year":"1993","journal-title":"Am J Physiol"},{"issue":"5","key":"10.1016\/j.bpg.2014.10.001_bib56","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1177\/000313481307900519","article-title":"Gastric electrical stimulation for abdominal pain in patients with symptoms of gastroparesis","volume":"79","author":"Lahr","year":"2013","journal-title":"Am Surg"},{"issue":"12","key":"10.1016\/j.bpg.2014.10.001_bib57","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0047849","article-title":"Gastric electrical stimulation decreases gastric distension-induced central nociception response through direct action on primary afferents","volume":"7","author":"Ouelaa","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.bpg.2014.10.001_bib58","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/1744-9081-9-46","article-title":"Experimental gastritis leads to anxiety- and depression-like behaviors in female but not male rats","volume":"9","author":"Luo","year":"2013","journal-title":"Behav Brain Funct"},{"issue":"5","key":"10.1016\/j.bpg.2014.10.001_bib59","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0019498","article-title":"Transient gastric irritation in the neonatal rats leads to changes in hypothalamic CRF expression, depression- and anxiety-like behavior as adults","volume":"6","author":"Liu","year":"2011","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.bpg.2014.10.001_bib60","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/0016-5085(95)90308-9","article-title":"Gastrointestinal sensory function in functional dyspepsia","volume":"109","author":"Holtmann","year":"1995","journal-title":"Gastroenterology"},{"issue":"6","key":"10.1016\/j.bpg.2014.10.001_bib61","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0065870","article-title":"Whole-brain functional connectivity identification of functional dyspepsia","volume":"8","author":"Nan","year":"2013","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.bpg.2014.10.001_bib62","doi-asserted-by":"crossref","first-page":"13","DOI":"10.5056\/jnm.2012.18.1.13","article-title":"Psychological co-morbidity in functional gastrointestinal disorders: epidemiology, mechanisms and management","volume":"18","author":"Wu","year":"2012","journal-title":"J\u00a0Neurogastroenterol Motil"},{"issue":"1","key":"10.1016\/j.bpg.2014.10.001_bib63","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1365-2982.2008.01178.x","article-title":"Influence of abuse history on gastric sensorimotor function in functional dyspepsia","volume":"21","author":"Geeraerts","year":"2009","journal-title":"Neurogastroenterol Motil"},{"issue":"6","key":"10.1016\/j.bpg.2014.10.001_bib64","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1176\/appi.ajp.2013.12070950","article-title":"Decreased cortical representation of genital somatosensory field after childhood sexual abuse","volume":"170","author":"Heim","year":"2013","journal-title":"Am J Psychiatry"},{"issue":"4","key":"10.1016\/j.bpg.2014.10.001_bib65","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.eurpsy.2012.03.002","article-title":"Reduced thalamic volume in men with antisocial personality disorder or schizophrenia and a history of serious violence and childhood abuse","volume":"28","author":"Kumari","year":"2013","journal-title":"Eur Psychiatry"},{"issue":"7","key":"10.1016\/j.bpg.2014.10.001_bib66","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/BF01700162","article-title":"Gastric emptying following brain injury: effects of choice of sedation and intracranial pressure","volume":"21","author":"McArthur","year":"1995","journal-title":"Intensive Care Med"},{"issue":"9","key":"10.1016\/j.bpg.2014.10.001_bib67","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1111\/j.1365-2826.2009.01896.x","article-title":"Ghrelin and dopamine: new insights on the peripheral regulation of appetite","volume":"21","author":"Abizaid","year":"2009","journal-title":"J\u00a0Neuroendocrinol"},{"issue":"5","key":"10.1016\/j.bpg.2014.10.001_bib68","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.physbeh.2004.04.014","article-title":"Gastric capacity, test meal intake, and appetitive hormones in binge eating disorder","volume":"81","author":"Geliebter","year":"2004","journal-title":"Physiol Behav"},{"key":"10.1016\/j.bpg.2014.10.001_bib69","doi-asserted-by":"crossref","first-page":"638203","DOI":"10.1155\/2014\/638203","article-title":"Comparison of the effectiveness of four bariatric surgery procedures in obese patients with type 2 diabetes: a retrospective study","volume":"2014","author":"Pham","year":"2014","journal-title":"J Obes"},{"issue":"1","key":"10.1016\/j.bpg.2014.10.001_bib70","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1159\/000360433","article-title":"Gastric bypass: current results and different techniques","volume":"31","author":"Vines","year":"2014","journal-title":"Dig Surg"},{"key":"10.1016\/j.bpg.2014.10.001_bib71","doi-asserted-by":"crossref","DOI":"10.1038\/nutd.2014.24","article-title":"Long-term changes in the ghrelin-CB1R axis associated with the maintenance of lower body weight after sleeve gastrectomy","volume":"4","author":"Fedonidis","year":"2014","journal-title":"Nutr Diabetes"},{"issue":"8","key":"10.1016\/j.bpg.2014.10.001_bib72","doi-asserted-by":"crossref","first-page":"2553","DOI":"10.1007\/s00221-014-4007-9","article-title":"Gastric dysrhythmias: a potential objective measure of nausea","volume":"232","author":"Koch","year":"2014","journal-title":"Exp Brain Res"},{"issue":"3","key":"10.1016\/j.bpg.2014.10.001_bib73","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s11154-014-9289-5","article-title":"Effects of GLP-1 on appetite and weight","volume":"15","author":"Shah","year":"2014","journal-title":"Rev Endocr Metab Disord"},{"issue":"1","key":"10.1016\/j.bpg.2014.10.001_bib74","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.brainres.2006.06.090","article-title":"Central glucagon like peptide-1 delays solid gastric emptying via central CRF and peripheral sympathetic pathway in rats","volume":"1111","author":"Nakade","year":"2006","journal-title":"Brain Res"},{"issue":"4","key":"10.1016\/j.bpg.2014.10.001_bib75","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1023\/B:DDAS.0000026317.00071.75","article-title":"Clinical presentation and personality factors are predictors of the response to treatment in patients with functional dyspepsia: a randomized, double-blind placebo-controlled crossover study","volume":"49","author":"Holtmann","year":"2004","journal-title":"Dig Dis Sci"},{"issue":"8","key":"10.1016\/j.bpg.2014.10.001_bib76","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1007\/s10620-014-3063-0","article-title":"Prevalence of Helicobacter pylori infection worldwide: a systematic review of studies with national coverage","volume":"59","author":"Peleteiro","year":"2014","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.bpg.2014.10.001_bib77","series-title":"Digestive tract microbiota in healthy volunteers","first-page":"47","author":"Zilberstein","year":"2007"},{"issue":"10","key":"10.1016\/j.bpg.2014.10.001_bib78","doi-asserted-by":"crossref","first-page":"e25792","DOI":"10.1371\/journal.pone.0025792","article-title":"Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes","volume":"6","author":"Brown","year":"2011","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.bpg.2014.10.001_bib79","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1053\/j.gastro.2007.01.046","article-title":"Immune activation in patients with irritable bowel syndrome","volume":"132","author":"Liebregts","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bpg.2014.10.001_bib80","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/1745-0179-4-15","article-title":"Psychological problems in gastroenterology outpatients: a South Australian experience. Psychological co-morbidity in IBD, IBS and hepatitis C","volume":"4","author":"Mikocka-Walus","year":"2008","journal-title":"Clin Pract Epidemiol Ment Health"},{"issue":"2","key":"10.1016\/j.bpg.2014.10.001_bib81","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S1542-3565(03)00315-X","article-title":"Determinants of health-related quality of life in patients with chronic liver diseases","volume":"2","author":"Hauser","year":"2004","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"2","key":"10.1016\/j.bpg.2014.10.001_bib82","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0016-5085(87)91028-6","article-title":"Gastric campylobacter-like organisms, gastritis, and peptic ulcer disease","volume":"93","author":"Blaser","year":"1987","journal-title":"Gastroenterology"},{"issue":"7","key":"10.1016\/j.bpg.2014.10.001_bib83","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1111\/j.1742-1241.2008.01763.x","article-title":"State and trait anxiety and depression in patients affected by gastrointestinal diseases: psychometric evaluation of 1641 patients referred to an internal medicine outpatient setting","volume":"62","author":"Addolorato","year":"2008","journal-title":"Int J Clin Pract"},{"issue":"1","key":"10.1016\/j.bpg.2014.10.001_bib84","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1111\/apt.12790","article-title":"Review article: associations between Helicobacter pyloriand obesity \u2013 an ecological study","volume":"40","author":"Lender","year":"2014","journal-title":"Aliment Pharmacol Ther"},{"issue":"1471","key":"10.1016\/j.bpg.2014.10.001_bib85","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1098\/rstb.2006.1856","article-title":"Gastrointestinal hormones regulating appetite","volume":"361","author":"Chaudhri","year":"2006","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"issue":"11","key":"10.1016\/j.bpg.2014.10.001_bib86","doi-asserted-by":"crossref","first-page":"2256","DOI":"10.1016\/j.peptides.2011.04.010","article-title":"Ghrelin-mediated appetite regulation in the central nervous system","volume":"32","author":"Kirsz","year":"2011","journal-title":"Peptides"},{"issue":"Suppl. 2","key":"10.1016\/j.bpg.2014.10.001_bib87","first-page":"7","article-title":"Brain-gut and appetite regulating hormones in the control of gastric secretion and mucosal protection","volume":"59","author":"Konturek","year":"2008","journal-title":"J Physiol Pharmacol"},{"issue":"3","key":"10.1016\/j.bpg.2014.10.001_bib88","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.nut.2010.07.004","article-title":"Diverse roles of leptin in the gastrointestinal tract: modulation of motility, absorption, growth, and inflammation","volume":"27","author":"Yarandi","year":"2011","journal-title":"Nutrition"}],"container-title":["Best Practice & Research Clinical Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521691814001528?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521691814001528?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T19:06:28Z","timestamp":1717441588000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521691814001528"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12]]},"references-count":88,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["S1521691814001528"],"URL":"https:\/\/doi.org\/10.1016\/j.bpg.2014.10.001","relation":{},"ISSN":["1521-6918"],"issn-type":[{"value":"1521-6918","type":"print"}],"subject":[],"published":{"date-parts":[[2014,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The stomach\u2013brain axis","name":"articletitle","label":"Article Title"},{"value":"Best Practice & Research Clinical Gastroenterology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bpg.2014.10.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}