{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T08:48:07Z","timestamp":1787993287008,"version":"build-2784847793"},"reference-count":77,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Best Practice & Research Clinical Gastroenterology"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.bpg.2025.102058","type":"journal-article","created":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T17:58:41Z","timestamp":1761674321000},"page":"102058","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Endoscopic ultrasound through-the-needle biopsy of pancreatic cystic neoplasms: Update on indications, safety profile, and research directions"],"prefix":"10.1016","volume":"81","author":[{"given":"Joana","family":"Mota","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiago","family":"Ribeiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Cristina","family":"Conti Bellocchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicol\u00f2","family":"De Pretis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Frulloni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne","family":"Lopes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sokol","family":"Sina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jahnvi","family":"Dhar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayanta","family":"Samanta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilherme","family":"Macedo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filipe","family":"Vilas-Boas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4560-8741","authenticated-orcid":false,"given":"Stefano Francesco","family":"Crin\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bpg.2025.102058_bib1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.pan.2023.12.009","article-title":"International evidence-based Kyoto guidelines for the management of intraductal papillary mucinous neoplasm of the pancreas","volume":"24","author":"Ohtsuka","year":"2024","journal-title":"Pancreatology"},{"key":"10.1016\/j.bpg.2025.102058_bib2","first-page":"375","article-title":"Diagnosis and management of cystic lesions of the pancreas","volume":"6","author":"Brugge","year":"2015","journal-title":"J Gastrointest Oncol"},{"key":"10.1016\/j.bpg.2025.102058_bib3","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1056\/NEJMra2309041","article-title":"Pancreatic cysts","volume":"391","author":"Gonda","year":"2024","journal-title":"N Engl J Med"},{"key":"10.1016\/j.bpg.2025.102058_bib4","doi-asserted-by":"crossref","DOI":"10.3390\/cancers16244268","article-title":"Advances for managing pancreatic cystic lesions: integrating imaging and AI innovations","volume":"16","author":"Seyithanoglu","year":"2024","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.bpg.2025.102058_bib5","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1016\/j.cgh.2024.02.018","article-title":"Global prevalence of pancreatic cystic lesions in the general population on magnetic resonance imaging: a systematic review and meta-analysis","volume":"22","author":"Vilela","year":"2024","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.bpg.2025.102058_bib6","doi-asserted-by":"crossref","DOI":"10.3748\/wjg.v31.i1.101082","article-title":"Endoscopic techniques for the diagnosis of pancreatic cystic lesions","volume":"31","author":"Singh","year":"2025","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.bpg.2025.102058_bib7","article-title":"Diagnosis and management of pancreatic cysts: a comprehensive review of the literature","volume":"13","author":"Singh","year":"2023","journal-title":"Diagnostics (Basel)"},{"key":"10.1016\/j.bpg.2025.102058_bib8","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1055\/a-1915-1812","article-title":"Wet-suction versus slow-pull technique for endoscopic ultrasound-guided fine-needle biopsy: a multicenter, randomized, crossover trial","volume":"55","author":"Crino","year":"2023","journal-title":"Endoscopy"},{"key":"10.1016\/j.bpg.2025.102058_bib9","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.gie.2023.01.024","article-title":"Comparative diagnostic performance of different techniques for EUS-guided fine-needle biopsy sampling of solid pancreatic masses: a network meta-analysis","volume":"97","author":"Facciorusso","year":"2023","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2025.102058_bib10","doi-asserted-by":"crossref","first-page":"458","DOI":"10.4103\/EUS-D-22-00026","article-title":"Comparison between EUS-guided fine-needle biopsy with or without rapid on-site evaluation for tissue sampling of solid pancreatic lesions: a systematic review and meta-analysis","volume":"11","author":"Facciorusso","year":"2022","journal-title":"Endosc Ultrasound"},{"key":"10.1016\/j.bpg.2025.102058_bib11","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1016\/j.surg.2023.07.016","article-title":"Pancreatic cystic neoplasms: still high rates of preoperative misdiagnosis in the guidelines and endoscopic ultrasound era","volume":"174","author":"Salvia","year":"2023","journal-title":"Surgery"},{"key":"10.1016\/j.bpg.2025.102058_bib12","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1111\/den.13626","article-title":"Diagnostic performance of endoscopic ultrasound through-the-needle microforceps biopsy of pancreatic cystic lesions: systematic review with meta-analysis","volume":"32","author":"Tacelli","year":"2020","journal-title":"Dig Endosc"},{"key":"10.1016\/j.bpg.2025.102058_bib13","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1159\/000430290","article-title":"EUS-guided FNA for diagnosis of pancreatic cystic lesions: a meta-analysis","volume":"36","author":"Wang","year":"2015","journal-title":"Cellular Physiology and Biochemistry"},{"key":"10.1016\/j.bpg.2025.102058_bib14","doi-asserted-by":"crossref","DOI":"10.1136\/bmjgast-2023-001184","article-title":"EUS-guided through the needle microbiopsy: a useful adjunct in the investigation of pancreatic cystic lesions","volume":"10","author":"Ahmed","year":"2023","journal-title":"BMJ Open Gastroenterol"},{"key":"10.1016\/j.bpg.2025.102058_bib15","doi-asserted-by":"crossref","first-page":"e131","DOI":"10.1097\/MCG.0000000000001507","article-title":"Intracystic glucose levels in differentiating mucinous from nonmucinous pancreatic cysts: a systematic review and meta-analysis","volume":"56","author":"Mohan","year":"2022","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.bpg.2025.102058_bib16","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1038\/s41395-018-0124-6","article-title":"Beyond pancreatic cyst epithelium: evidence of ovarian-like stroma in EUS-guided through-the-needle micro-forceps biopsy specimens","volume":"113","author":"Crin\u00f2","year":"2018","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.bpg.2025.102058_bib17","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1055\/a-1831-5385","article-title":"Predictors of adverse events after endoscopic ultrasound-guided through-the-needle biopsy of pancreatic cysts: a recursive partitioning analysis","volume":"54","author":"Facciorusso","year":"2022","journal-title":"Endoscopy"},{"key":"10.1016\/j.bpg.2025.102058_bib18","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/j.gie.2019.05.009","article-title":"Association between macroscopically visible tissue samples and diagnostic accuracy of EUS-guided through-the-needle microforceps biopsy sampling of pancreatic cystic lesions","volume":"90","author":"Crino","year":"2019","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2025.102058_bib19","article-title":"Endoscopic ultrasound-guided through-the-needle biopsy: a narrative review of the technique and its emerging role in pancreatic cyst diagnosis","volume":"14","author":"Vilas-Boas","year":"2024","journal-title":"Diagnostics (Basel)"},{"key":"10.1016\/j.bpg.2025.102058_bib20","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1055\/a-2524-2596","article-title":"Endoscopic ultrasound-guided tissue sampling: European society of gastrointestinal endoscopy (ESGE) technical and technology review","volume":"57","author":"Facciorusso","year":"2025","journal-title":"Endoscopy"},{"key":"10.1016\/j.bpg.2025.102058_bib21","doi-asserted-by":"crossref","DOI":"10.1093\/ajcp\/aqaf050","article-title":"Endoscopic ultrasound-guided pancreatic core-needle\/microforceps biopsy is a valuable diagnostic tool for pancreatic lesions: experience from a large academic institution","author":"Shafi","year":"2025","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.bpg.2025.102058_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.cgh.2015.08.038","article-title":"Association between advances in high-resolution cross-section imaging technologies and increase in prevalence of pancreatic cysts from 2005 to 2014","volume":"14","author":"Moris","year":"2016","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.bpg.2025.102058_bib23","doi-asserted-by":"crossref","DOI":"10.3390\/cancers16061183","article-title":"Molecular pathology of pancreatic cystic lesions with a focus on malignant progression","volume":"16","author":"Hu","year":"2024","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.bpg.2025.102058_bib24","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1001\/jama.2021.13027","article-title":"Pancreatic cancer: a review","volume":"326","author":"Park","year":"2021","journal-title":"JAMA"},{"key":"10.1016\/j.bpg.2025.102058_bib25","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1016\/j.surg.2018.07.014","article-title":"Surgical overtreatment of pancreatic intraductal papillary mucinous neoplasms: do the 2017 international consensus guidelines improve clinical decision making?","volume":"164","author":"Sharib","year":"2018","journal-title":"Surgery"},{"key":"10.1016\/j.bpg.2025.102058_bib26","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.pan.2020.01.006","article-title":"Psychological distress in patients under surveillance for intraductal papillary mucinous neoplasms of the pancreas: the \"Sword of Damocles\" effect calls for an integrated medical and psychological approach a prospective analysis","volume":"20","author":"Marinelli","year":"2020","journal-title":"Pancreatology"},{"key":"10.1016\/j.bpg.2025.102058_bib27","article-title":"Deep learning for automatic differentiation of mucinous versus non-mucinous pancreatic cystic lesions: a pilot study","volume":"12","author":"Vilas-Boas","year":"2022","journal-title":"Diagnostics (Basel)"},{"key":"10.1016\/j.bpg.2025.102058_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.pan.2025.05.011","article-title":"Towards automating risk stratification of intraductal papillary mucinous neoplasms: artificial intelligence advances beyond human expertise with confocal laser endomicroscopy","author":"Krishna","year":"2025","journal-title":"Pancreatology"},{"key":"10.1016\/j.bpg.2025.102058_bib29","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.3390\/diagnostics14151587","article-title":"Endoscopic ultrasound-guided through-the-needle biopsy: a narrative review of the technique and its emerging role in pancreatic cyst diagnosis","volume":"14","author":"Vilas-Boas","year":"2024","journal-title":"Diagnostics"},{"key":"10.1016\/j.bpg.2025.102058_bib30","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1055\/a-1611-5091","article-title":"Endoscopic tissue sampling - part 1: upper gastrointestinal and hepatopancreatobiliary tracts. European society of gastrointestinal endoscopy (ESGE) guideline","volume":"53","author":"Pouw","year":"2021","journal-title":"Endoscopy"},{"key":"10.1016\/j.bpg.2025.102058_bib31","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.gie.2021.09.035","article-title":"Efficacy and safety of EUS-guided through-the-needle microforceps biopsy sampling in categorizing the type of pancreatic cystic lesions","volume":"95","author":"Cho","year":"2022","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2025.102058_bib32","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.gie.2020.05.009","article-title":"Time to standardize through-the-needle biopsy specimen handling","volume":"92","author":"Crin\u00f3","year":"2020","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2025.102058_bib33","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1097\/eus.0000000000000091","article-title":"Value of EUS-guided through-the-needle biopsy in the diagnosis of pancreatic cystic neoplasms: an 8-year experience","volume":"13","author":"Cheng","year":"2024","journal-title":"Endosc Ultrasound"},{"key":"10.1016\/j.bpg.2025.102058_bib34","doi-asserted-by":"crossref","first-page":"531","DOI":"10.4253\/wjge.v11.i11.531","article-title":"Endoscopic ultrasound-through-the-needle biopsy in pancreatic cystic lesions: a large single center experience","volume":"11","author":"Hashimoto","year":"2019","journal-title":"World J Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2025.102058_bib35","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/j.gie.2017.12.025","article-title":"Technical feasibility, diagnostic yield, and safety of microforceps biopsies during EUS evaluation of pancreatic cystic lesions (with video)","volume":"87","author":"Mittal","year":"2018","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2025.102058_bib36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.gie.2020.01.038","article-title":"Diagnostic yield of EUS-guided through-the-needle biopsy in pancreatic cysts: a meta-analysis","volume":"92","author":"Facciorusso","year":"2020","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2025.102058_bib37","doi-asserted-by":"crossref","first-page":"E656","DOI":"10.1055\/a-1119-6543","article-title":"Diagnostic yield of EUS-guided through-the-needle microforceps biopsy versus EUS-FNA of pancreatic cystic lesions: a systematic review and meta-analysis","volume":"8","author":"Westerveld","year":"2020","journal-title":"Endosc Int Open"},{"key":"10.1016\/j.bpg.2025.102058_bib38","doi-asserted-by":"crossref","first-page":"E1280","DOI":"10.1055\/a-1194-4085","article-title":"Endoscopic ultrasound-guided through-the-needle microforceps biopsy improves diagnostic yield for pancreatic cystic lesions: a systematic review and meta-analysis","volume":"8","author":"McCarty","year":"2020","journal-title":"Endosc Int Open"},{"key":"10.1016\/j.bpg.2025.102058_bib39","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s12029-023-00949-w","article-title":"Value of endoscopic ultrasound-guided through-the-needle biopsy in pancreatic cystic lesions. A systematic review and meta-analysis","volume":"55","author":"Gopakumar","year":"2024","journal-title":"J Gastrointest Cancer"},{"key":"10.1016\/j.bpg.2025.102058_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.prp.2021.153368","article-title":"Diagnostic accuracy of EUS-guided through-the-needle-biopsies and simultaneously obtained fine needle aspiration for cytology from pancreatic cysts: a systematic review and meta-analysis","volume":"220","author":"Rift","year":"2021","journal-title":"Pathol Res Pract"},{"key":"10.1016\/j.bpg.2025.102058_bib41","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.gie.2009.10.027","article-title":"A lexicon for endoscopic adverse events: report of an ASGE workshop","volume":"71","author":"Cotton","year":"2010","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2025.102058_bib42","doi-asserted-by":"crossref","DOI":"10.1111\/den.15060","article-title":"World endoscopy organization guidelines on endoscopic retrograde cholangiopancreatography biliary cannulation and sphincterotomy techniques","author":"Crin\u00f2","year":"2025","journal-title":"Dig Endosc"},{"key":"10.1016\/j.bpg.2025.102058_bib43","doi-asserted-by":"crossref","first-page":"220","DOI":"10.4103\/eus.eus_12_20","article-title":"EUS-guided through-the-needle microbiopsy of pancreatic cysts: technical aspects (with video)","volume":"9","author":"Kovacevic","year":"2020","journal-title":"Endosc Ultrasound"},{"key":"10.1016\/j.bpg.2025.102058_bib44","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1080\/17474124.2020.1797486","article-title":"Use of antibiotic prophylaxis is not needed for endoscopic ultrasound-guided fine-needle aspiration of pancreatic cysts: a meta-analysis","volume":"14","author":"Facciorusso","year":"2020","journal-title":"Expet Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.bpg.2025.102058_bib45","article-title":"Impact of antibiotic prophylaxis on infection rate after endoscopic ultrasound through-the-needle biopsy of pancreatic cysts: a propensity score-matched study","volume":"12","author":"Facciorusso","year":"2022","journal-title":"Diagnostics (Basel)"},{"key":"10.1016\/j.bpg.2025.102058_bib46","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1016\/j.gie.2010.08.036","article-title":"Direct intracystic biopsy and pancreatic cystoscopy through a 19-gauge needle EUS (with videos)","volume":"72","author":"Aparicio","year":"2010","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2025.102058_bib47","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1097\/eus.0000000000000062","article-title":"EUS-guided through-the-needle microforceps biopsy for pancreatic cysts: why no widespread adoption?","volume":"13","author":"Moond","year":"2024","journal-title":"Endosc Ultrasound"},{"key":"10.1016\/j.bpg.2025.102058_bib48","article-title":"Endoscopic ultrasound-guided pancreatic tissue sampling: lesion assessment, needles, and techniques","volume":"60","author":"Dhar","year":"2024","journal-title":"Medicina (Kaunas)"},{"key":"10.1016\/j.bpg.2025.102058_bib49","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1016\/j.cgh.2018.11.027","article-title":"Histologic analysis of endoscopic ultrasound-guided through the needle microforceps biopsies accurately identifies mucinous pancreas cysts","volume":"17","author":"Yang","year":"2019","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.bpg.2025.102058_bib50","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1055\/a-1214-6043","article-title":"Clinical impact of endoscopic ultrasound-guided through-the-needle microbiopsy in patients with pancreatic cysts","volume":"53","author":"Kovacevic","year":"2021","journal-title":"Endoscopy"},{"key":"10.1016\/j.bpg.2025.102058_bib51","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/j.gie.2016.03.1502","article-title":"Pancreatic cyst epithelial denudation: a natural phenomenon in the absence of treatment","volume":"84","author":"G\u00f3mez","year":"2016","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2025.102058_bib52","doi-asserted-by":"crossref","first-page":"145","DOI":"10.4103\/EUS-D-21-00271","article-title":"EUS-guided through-the-needle microforceps biopsy for diagnosis of tubercular lymphadenitis mimicking pancreatic cystic lesion (with video)","volume":"12","author":"Rana","year":"2023","journal-title":"Endosc Ultrasound"},{"key":"10.1016\/j.bpg.2025.102058_bib53","article-title":"Peritoneal adenocarcinoma diagnosed by endoscopic ultrasound-guided through-the-needle biopsy","volume":"56","author":"Gong","year":"2024","journal-title":"Endoscopy"},{"key":"10.1016\/j.bpg.2025.102058_bib54","article-title":"Rare pancreatic\/peripancreatic cystic lesions can be accurately characterized by EUS with through-the-needle Biopsy-A unique pictorial essay with clinical and histopathological correlations","volume":"13","author":"Conti Bellocchi","year":"2023","journal-title":"Diagnostics (Basel)"},{"key":"10.1016\/j.bpg.2025.102058_bib55","doi-asserted-by":"crossref","first-page":"695","DOI":"10.3390\/medicina60050695","article-title":"Revolutionizing the pancreatic tumor diagnosis: emerging trends in imaging technologies: a systematic review","volume":"60","author":"\u0218olea","year":"2024","journal-title":"Medicina"},{"key":"10.1016\/j.bpg.2025.102058_bib56","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.dld.2020.06.038","article-title":"Differential diagnosis of pancreatic cysts: a prospective study on the role of intra-cystic glucose concentration","volume":"52","author":"Ribaldone","year":"2020","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.bpg.2025.102058_bib57","article-title":"Genomic alterations in pancreatic cystic neoplasms: from molecular characterization to precision clinical management-conventional review","author":"Yang","year":"2025","journal-title":"Int J Surg"},{"key":"10.1016\/j.bpg.2025.102058_bib58","doi-asserted-by":"crossref","first-page":"434","DOI":"10.5946\/ce.2023.157","article-title":"Endoscopic ultrasound-guided needle-based confocal laser endomicroscopy for pancreatic cystic lesions: current status and future prospects","volume":"57","author":"Wu","year":"2024","journal-title":"Clin Endosc"},{"key":"10.1016\/j.bpg.2025.102058_bib59","doi-asserted-by":"crossref","DOI":"10.3390\/jcm14113825","article-title":"Endoscopic ultrasound-guided pancreatic cystic fluid biochemical and genetic analysis for the differentiation between mucinous and non-mucinous pancreatic cystic lesions","volume":"14","author":"Bruni","year":"2025","journal-title":"J Clin Med"},{"key":"10.1016\/j.bpg.2025.102058_bib60","doi-asserted-by":"crossref","DOI":"10.1053\/j.gastro.2022.09.028","article-title":"Prospective, multi-institutional, real-time next-generation sequencing of pancreatic cyst fluid reveals diverse genomic alterations that improve the clinical management of pancreatic cysts","volume":"164","author":"Paniccia","year":"2023","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bpg.2025.102058_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.gie.2025.01.005","article-title":"Clinical utility of incorporating next-generation sequencing results in the management algorithm of pancreatic cysts","volume":"102","author":"Jones","year":"2025","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2025.102058_bib62","doi-asserted-by":"crossref","DOI":"10.1016\/j.gie.2022.08.008","article-title":"Targeted next-generation sequencing of EUS-guided through-the-needle-biopsy sampling from pancreatic cystic lesions","volume":"97","author":"Rift","year":"2023","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2025.102058_bib63","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1111\/his.13949","article-title":"Next-generation sequencing of endoscopic ultrasound guided microbiopsies from pancreatic cystic neoplasms","volume":"75","author":"Vestrup Rift","year":"2019","journal-title":"Histopathology"},{"key":"10.1016\/j.bpg.2025.102058_bib64","doi-asserted-by":"crossref","first-page":"E983","DOI":"10.1055\/a-2163-8805","article-title":"Next-generation sequencing of pancreatic cyst wall specimens obtained using micro-forceps for improving diagnostic accuracy","volume":"11","author":"Astbury","year":"2023","journal-title":"Endosc Int Open"},{"key":"10.1016\/j.bpg.2025.102058_bib65","doi-asserted-by":"crossref","first-page":"2811","DOI":"10.1007\/s10620-023-07904-6","article-title":"Pancreatic cancer biomarkers: oncogenic mutations, tissue and liquid biopsies, and Radiomics-A review","volume":"68","author":"Amaral","year":"2023","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.bpg.2025.102058_bib66","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.giec.2023.03.009","article-title":"Blood-based biomarkers in the diagnosis and risk stratification of pancreatic cysts","volume":"33","author":"Peller","year":"2023","journal-title":"Gastrointest Endosc Clin N Am"},{"key":"10.1016\/j.bpg.2025.102058_bib67","doi-asserted-by":"crossref","DOI":"10.3390\/cancers13040769","article-title":"Multi-omic biomarkers as potential tools for the characterisation of pancreatic cystic lesions and cancer: innovative patient data integration","volume":"13","author":"Kane","year":"2021","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.bpg.2025.102058_bib68","doi-asserted-by":"crossref","DOI":"10.1097\/MPA.0000000000002276","article-title":"Poor adherence to Most recent guidelines on pancreatic cysts management: an ongoing problem","volume":"53","author":"Zouridis","year":"2024","journal-title":"Pancreas"},{"key":"10.1016\/j.bpg.2025.102058_bib69","doi-asserted-by":"crossref","first-page":"3668","DOI":"10.1245\/s10434-014-3739-x","article-title":"Role of a multidisciplinary clinic in the management of patients with pancreatic cysts: a single-center cohort study","volume":"21","author":"Lennon","year":"2014","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.bpg.2025.102058_bib70","doi-asserted-by":"crossref","first-page":"243","DOI":"10.14309\/ajg.0000000000002088","article-title":"Comparative performance of endoscopic ultrasound-based techniques in patients with pancreatic cystic lesions: a network meta-analysis","volume":"118","author":"Li","year":"2023","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.bpg.2025.102058_bib71","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.path.2024.04.007","article-title":"Pancreas fine needle aspiration: current and future impact on patient care","volume":"17","author":"Kwan","year":"2024","journal-title":"Surg Pathol Clin"},{"key":"10.1016\/j.bpg.2025.102058_bib72","article-title":"Diagnostic yield of endoscopic ultrasound-guided fine-needle aspiration-based cytology for distinguishing malignant and benign pancreatic cystic lesions: a systematic review and meta-analysis","volume":"20","author":"Ding","year":"2025","journal-title":"PLoS One"},{"key":"10.1016\/j.bpg.2025.102058_bib73","first-page":"235","article-title":"EUS-guided needle-based confocal laser endomicroscopy: a novel technique with emerging applications","volume":"11","author":"Bhutani","year":"2015","journal-title":"Gastroenterol Hepatol (N Y)"},{"key":"10.1016\/j.bpg.2025.102058_bib74","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1080\/13645706.2021.1888750","article-title":"Needle-based confocal laser endomicroscopy for diagnosis of pancreatic cystic lesions: a meta-analysis","volume":"31","author":"Wang","year":"2022","journal-title":"Minim Invasive Ther Allied Technol"},{"key":"10.1016\/j.bpg.2025.102058_bib75","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/j.gie.2019.07.011","article-title":"Interobserver agreement among expert pathologists on through-the-needle microforceps biopsy samples for evaluation of pancreatic cystic lesions","volume":"90","author":"Larghi","year":"2019","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.bpg.2025.102058_bib76","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/j.dld.2023.05.015","article-title":"A new tool for rapid evaluation of endoscopic ultrasound through the needle biopsy in pancreatic cystic neoplasm","volume":"55","author":"Stigliano","year":"2023","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.bpg.2025.102058_bib77","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1055\/a-1243-0545","article-title":"Through-the-needle microforceps biopsy: a powerful tool but for selected patients","volume":"53","author":"Crin\u00f2","year":"2021","journal-title":"Endoscopy"}],"container-title":["Best Practice & Research Clinical Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S152169182500085X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S152169182500085X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T19:41:36Z","timestamp":1779306096000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S152169182500085X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":77,"alternative-id":["S152169182500085X"],"URL":"https:\/\/doi.org\/10.1016\/j.bpg.2025.102058","relation":{},"ISSN":["1521-6918"],"issn-type":[{"value":"1521-6918","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Endoscopic ultrasound through-the-needle biopsy of pancreatic cystic neoplasms: Update on indications, safety profile, and research directions","name":"articletitle","label":"Article Title"},{"value":"Best Practice & Research Clinical Gastroenterology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bpg.2025.102058","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"102058"}}