{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T16:16:03Z","timestamp":1788279363701,"version":"build-2803163510"},"reference-count":64,"publisher":"Elsevier BV","issue":"17","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["T32-GM008326C"],"award-info":[{"award-number":["T32-GM008326C"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["R35-GM142960"],"award-info":[{"award-number":["R35-GM142960"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000015","name":"U.S. Department of Energy","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000015","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000076","name":"National Science Foundation Directorate for Biological Sciences","doi-asserted-by":"publisher","award":["MCB-2046303"],"award-info":[{"award-number":["MCB-2046303"]}],"id":[{"id":"10.13039\/100000076","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006132","name":"US Department of Energy Office of Science","doi-asserted-by":"publisher","award":["DE-SC0022954"],"award-info":[{"award-number":["DE-SC0022954"]}],"id":[{"id":"10.13039\/100006132","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biophysical Journal"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.bpj.2026.07.026","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:10:40Z","timestamp":1785424240000},"page":"4796-4808","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Coupling between sterol and sphingolipid structure in ordered membrane domains"],"prefix":"10.1016","volume":"125","author":[{"given":"Israel","family":"Juarez-Contreras","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyesoo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9706-4294","authenticated-orcid":false,"given":"Itay","family":"Budin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bpj.2026.07.026_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemphyslip.2020.104984","article-title":"Bringing rafts to life: Lessons learned from lipid organization across diverse biological membranes","volume":"233","author":"Tsai","year":"2020","journal-title":"Chem. Phys. Lipids"},{"key":"10.1016\/j.bpj.2026.07.026_bib2","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.tcb.2020.01.009","article-title":"Lipid Rafts: Controversies Resolved, Mysteries Remain","volume":"30","author":"Levental","year":"2020","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.bpj.2026.07.026_bib3","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1016\/S0006-3495(01)76114-0","article-title":"Lipid rafts reconstituted in model membranes","volume":"80","author":"Dietrich","year":"2001","journal-title":"Biophys. J."},{"key":"10.1016\/j.bpj.2026.07.026_bib4","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1016\/S0006-3495(01)75803-1","article-title":"Characterization of cholesterol-sphingomyelin domains and their dynamics in bilayer membranes","volume":"81","author":"Samsonov","year":"2001","journal-title":"Biophys. J."},{"key":"10.1016\/j.bpj.2026.07.026_bib5","doi-asserted-by":"crossref","DOI":"10.1103\/PhysRevLett.89.268101","article-title":"Organization in lipid membranes containing cholesterol","volume":"89","author":"Veatch","year":"2002","journal-title":"Phys. Rev. Lett."},{"key":"10.1016\/j.bpj.2026.07.026_bib6","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2401241121","article-title":"Sterol-lipids enable large-scale, liquid-liquid phase separation in bilayer membranes of only two components","volume":"121","author":"Wilson","year":"2024","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bpj.2026.07.026_bib7","doi-asserted-by":"crossref","first-page":"3074","DOI":"10.1016\/S0006-3495(03)74726-2","article-title":"Separation of liquid phases in giant vesicles of ternary mixtures of phospholipids and cholesterol","volume":"85","author":"Veatch","year":"2003","journal-title":"Biophys. J."},{"key":"10.1016\/j.bpj.2026.07.026_bib8","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1038\/nature02013","article-title":"Imaging coexisting fluid domains in biomembrane models coupling curvature and line tension","volume":"425","author":"Baumgart","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.bpj.2026.07.026_bib9","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/0005-2736(87)90020-4","article-title":"Phase equilibria in the phosphatidylcholine-cholesterol system","volume":"905","author":"Ipsen","year":"1987","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bpj.2026.07.026_bib10","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1529\/biophysj.105.067652","article-title":"Universal behavior of membranes with sterols","volume":"90","author":"Henriksen","year":"2006","journal-title":"Biophys. J."},{"key":"10.1016\/j.bpj.2026.07.026_bib11","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1194\/jlr.M003467","article-title":"Comparison of the liquid-ordered bilayer phases containing cholesterol or 7-dehydrocholesterol in modeling Smith-Lemli-Opitz syndrome","volume":"51","author":"Staneva","year":"2010","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bpj.2026.07.026_bib12","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/S0163-7827(01)00020-0","article-title":"Cholesterol interactions with phospholipids in membranes","volume":"41","author":"Ohvo-Rekil\u00e4","year":"2002","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.bpj.2026.07.026_bib13","doi-asserted-by":"crossref","first-page":"33540","DOI":"10.1074\/jbc.M104776200","volume":"276","author":"Xu","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bpj.2026.07.026_bib14","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1021\/bi992543v","article-title":"The effect of sterol structure on membrane lipid domains reveals how cholesterol can induce lipid domain formation","volume":"39","author":"Xu","year":"2000","journal-title":"Biochemistry"},{"key":"10.1016\/j.bpj.2026.07.026_bib15","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.adu7190","article-title":"Structural dissection of ergosterol metabolism reveals a pathway optimized for membrane phase separation","volume":"11","author":"Juarez-Contreras","year":"2025","journal-title":"Sci. Adv."},{"key":"10.1016\/j.bpj.2026.07.026_bib16","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1529\/biophysj.104.049635","article-title":"Sterol structure determines miscibility versus melting transitions in lipid vesicles","volume":"89","author":"Beattie","year":"2005","journal-title":"Biophys. J."},{"key":"10.1016\/j.bpj.2026.07.026_bib17","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1016\/j.bpj.2017.04.052","article-title":"Miscibility transition temperature scales with growth temperature in a zebrafish cell line","volume":"113","author":"Burns","year":"2017","journal-title":"Biophys. J."},{"key":"10.1016\/j.bpj.2026.07.026_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2023.105496","article-title":"Intracellular sphingolipid sorting drives membrane phase separation in the yeast vacuole","volume":"300","author":"Kim","year":"2024","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bpj.2026.07.026_bib19","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.chembiol.2025.12.006","article-title":"1-deoxysphingolipids dysregulate membrane properties and cargo trafficking in the early secretory pathway","volume":"33","author":"Tsai","year":"2026","journal-title":"Cell Chem. Biol."},{"key":"10.1016\/j.bpj.2026.07.026_bib20","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.1073\/pnas.0811700106","article-title":"Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry","volume":"106","author":"Ejsing","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bpj.2026.07.026_bib21","doi-asserted-by":"crossref","first-page":"5010","DOI":"10.1038\/s41467-025-60423-y","article-title":"Mechanisms of aureobasidin A inhibition and drug resistance in a fungal IPC synthase complex","volume":"16","author":"Wu","year":"2025","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bpj.2026.07.026_bib22","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2024.1409085","article-title":"Insights into the role of sterol metabolism in antifungal drug resistance: a mini-review","volume":"15","author":"Tanwar","year":"2024","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.bpj.2026.07.026_bib23","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0006-3495(84)84007-2","article-title":"Mattress model of lipid-protein interactions in membranes","volume":"46","author":"Mouritsen","year":"1984","journal-title":"Biophys. J."},{"key":"10.1016\/j.bpj.2026.07.026_bib24","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0005-2736(84)90562-5","article-title":"Interdigitated hydrocarbon chain packing causes the biphasic transition behavior in lipid\/alcohol suspensions","volume":"773","author":"Simon","year":"1984","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bpj.2026.07.026_bib25","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1016\/S0006-3495(99)77369-8","article-title":"A microscopic interaction model of maximum solubility of cholesterol in lipid bilayers","volume":"76","author":"Huang","year":"1999","journal-title":"Biophys. J."},{"key":"10.1016\/j.bpj.2026.07.026_bib26","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1016\/j.bbamem.2006.05.020","article-title":"Sphingolipids and the formation of sterol-enriched ordered membrane domains","volume":"1758","author":"Ramstedt","year":"2006","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bpj.2026.07.026_bib27","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/S0006-3495(99)77254-1","article-title":"Interaction of cholesterol with sphingomyelins and acyl-chain-matched phosphatidylcholines: a comparative study of the effect of the chain length","volume":"76","author":"Ramstedt","year":"1999","journal-title":"Biophys. J."},{"key":"10.1016\/j.bpj.2026.07.026_bib28","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1083\/jcb.17.3.609","article-title":"FINE STRUCTURE IN FROZEN-ETCHED YEAST CELLS","volume":"17","author":"Moor","year":"1963","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bpj.2026.07.026_bib29","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1083\/jcb.201301039","article-title":"Direct imaging reveals stable, micrometer-scale lipid domains that segregate proteins in live cells","volume":"202","author":"Toulmay","year":"2013","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bpj.2026.07.026_bib30","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.21690","article-title":"AMPK and vacuole-associated Atg14p orchestrate \u03bc-lipophagy for energy production and long-term survival under glucose starvation","volume":"6","author":"Seo","year":"2017","journal-title":"eLife"},{"key":"10.1016\/j.bpj.2026.07.026_bib31","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.25960","article-title":"Niemann-Pick type C proteins promote microautophagy by expanding raft-like membrane domains in the yeast vacuole","volume":"6","author":"Tsuji","year":"2017","journal-title":"eLife"},{"key":"10.1016\/j.bpj.2026.07.026_bib32","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1016\/j.bpj.2017.09.029","article-title":"Hallmarks of Reversible Separation of Living, Unperturbed Cell Membranes into Two Liquid Phases","volume":"113","author":"Rayermann","year":"2017","journal-title":"Biophys. J."},{"key":"10.1016\/j.bpj.2026.07.026_bib33","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2116007119","article-title":"Yeast cells actively tune their membranes to phase separate at temperatures that scale with growth temperatures","volume":"119","author":"Leveille","year":"2022","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bpj.2026.07.026_bib34","doi-asserted-by":"crossref","first-page":"47","DOI":"10.3109\/10409238309102790","article-title":"Sterol structure and membrane function","volume":"14","author":"Bloch","year":"1983","journal-title":"CRC Crit. Rev. Biochem."},{"key":"10.1016\/j.bpj.2026.07.026_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2026.111370","article-title":"Transport of sphingolipids by yeast Npc2 supports phase separation of the vacuole membrane","volume":"302","author":"Kim","year":"2026","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bpj.2026.07.026_bib36","doi-asserted-by":"crossref","first-page":"30224","DOI":"10.1074\/jbc.M110.123554","article-title":"Yeast lipids can phase-separate into micrometer-scale membrane domains","volume":"285","author":"Klose","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bpj.2026.07.026_bib37","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.ymben.2011.06.006","article-title":"A stable yeast strain efficiently producing cholesterol instead of ergosterol is functional for tryptophan uptake, but not weak organic acid resistance","volume":"13","author":"Souza","year":"2011","journal-title":"Metab. Eng."},{"key":"10.1016\/j.bpj.2026.07.026_bib38","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/bs.mie.2024.02.015","article-title":"Using the yeast vacuole as a system to test the lipidic drivers of membrane heterogeneity in living cells","volume":"700","author":"Kim","year":"2024","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.bpj.2026.07.026_bib39","doi-asserted-by":"crossref","DOI":"10.21769\/BioProtoc.2527","article-title":"Sterol analysis in Kluyveromyces lactis","volume":"7","author":"Gbelska","year":"2017","journal-title":"Bio. Protoc."},{"key":"10.1016\/j.bpj.2026.07.026_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbamem.2021.183794","article-title":"Broad lipid phase transitions in mammalian cell membranes measured by Laurdan fluorescence spectroscopy","volume":"1864","author":"F\u00e4rber","year":"2022","journal-title":"Biochim. Biophys. Acta. Biomembr."},{"key":"10.1016\/j.bpj.2026.07.026_bib41","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/j.bpj.2023.01.009","article-title":"Remodeling of yeast vacuole membrane lipidomes from the log (one phase) to stationary stage (two phases)","volume":"122","author":"Reinhard","year":"2023","journal-title":"Biophys. J."},{"key":"10.1016\/j.bpj.2026.07.026_bib42","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/BF00718783","article-title":"Membrane lipid domains and dynamics as detected by Laurdan fluorescence","volume":"5","author":"Parasassi","year":"1995","journal-title":"J. Fluoresc."},{"key":"10.1016\/j.bpj.2026.07.026_bib43","doi-asserted-by":"crossref","first-page":"4414","DOI":"10.1091\/mbc.e02-02-0116","article-title":"A specific structural requirement for ergosterol in long-chain fatty acid synthesis mutants important for maintaining raft domains in yeast","volume":"13","author":"Eisenkolb","year":"2002","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.bpj.2026.07.026_bib44","doi-asserted-by":"crossref","first-page":"3299","DOI":"10.1194\/jlr.M009449","article-title":"Lipidomics reveals a remarkable diversity of lipids in human plasma","volume":"51","author":"Quehenberger","year":"2010","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bpj.2026.07.026_bib45","doi-asserted-by":"crossref","first-page":"2696","DOI":"10.1016\/j.bpj.2008.12.3922","article-title":"Membrane fluidity and lipid order in ternary giant unilamellar vesicles using a new bodipy-cholesterol derivative","volume":"96","author":"Ariola","year":"2009","journal-title":"Biophys. J."},{"key":"10.1016\/j.bpj.2026.07.026_bib46","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1016\/j.bpj.2013.02.024","article-title":"Phase diagram and tie-line determination for the ternary mixture DOPC\/eSM\/cholesterol","volume":"104","author":"Bezlyepkina","year":"2013","journal-title":"Biophys. J."},{"key":"10.1016\/j.bpj.2026.07.026_bib47","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0005-2736(95)00117-L","article-title":"Molecular order and dynamics of phosphatidylcholine bilayer membranes in the presence of cholesterol, ergosterol and lanosterol: a comparative study using 2H-13C- and 31P-NMR spectroscopy","volume":"1238","author":"Urbina","year":"1995","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bpj.2026.07.026_bib48","doi-asserted-by":"crossref","first-page":"4745","DOI":"10.1021\/acs.jpclett.4c00385","article-title":"Nonstereotypical distribution and effect of ergosterol in lipid membranes","volume":"15","author":"Qian","year":"2024","journal-title":"J. Phys. Chem. Lett."},{"key":"10.1016\/j.bpj.2026.07.026_bib49","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.bpj.2011.12.038","article-title":"Role of unsaturated lipid and ergosterol in ethanol tolerance of model yeast biomembranes","volume":"102","author":"Vanegas","year":"2012","journal-title":"Biophys. J."},{"key":"10.1016\/j.bpj.2026.07.026_bib50","doi-asserted-by":"crossref","first-page":"6161","DOI":"10.1021\/acs.jpcb.9b03413","article-title":"Ergosterol-induced ordered phase in ternary lipid mixture systems of unsaturated and saturated phospholipid membranes","volume":"123","author":"Bui","year":"2019","journal-title":"J. Phys. Chem. B"},{"key":"10.1016\/j.bpj.2026.07.026_bib51","doi-asserted-by":"crossref","DOI":"10.1103\/PhysRevLett.94.148101","article-title":"Miscibility phase diagrams of giant vesicles containing sphingomyelin","volume":"94","author":"Veatch","year":"2005","journal-title":"Phys. Rev. Lett."},{"key":"10.1016\/j.bpj.2026.07.026_bib52","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1016\/S0006-3495(90)82637-0","article-title":"Phase fluctuation in phospholipid membranes revealed by Laurdan fluorescence","volume":"57","author":"Parasassi","year":"1990","journal-title":"Biophys. J."},{"key":"10.1016\/j.bpj.2026.07.026_bib53","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1023\/A:1020528716621","article-title":"Laurdan and Prodan as Polarity-Sensitive Fluorescent Membrane Probes","volume":"8","author":"Parasassi","year":"1998","journal-title":"J. Fluoresc."},{"key":"10.1016\/j.bpj.2026.07.026_bib54","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0009-3084(79)90102-6","article-title":"A spin label study of the effects of sterols on egg lecithin bilayers","volume":"23","author":"Semer","year":"1979","journal-title":"Chem. Phys. Lipids"},{"key":"10.1016\/j.bpj.2026.07.026_bib55","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.1016\/j.bpj.2016.03.042","article-title":"Mixing Temperatures of Bilayers Not Simply Related to Thickness Differences between Lo and Ld Phases","volume":"110","author":"Bleecker","year":"2016","journal-title":"Biophys. J."},{"key":"10.1016\/j.bpj.2026.07.026_bib56","doi-asserted-by":"crossref","first-page":"5882","DOI":"10.1039\/c0sm00373e","article-title":"Solubility limits of cholesterol, lanosterol, ergosterol, stigmasterol, and \u03b2-sitosterol in electroformed lipid vesicles","volume":"6","author":"Stevens","year":"2010","journal-title":"Soft Matter"},{"key":"10.1016\/j.bpj.2026.07.026_bib57","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.1016\/j.bpj.2016.04.003","article-title":"Comparative Study of the Condensing Effects of Ergosterol and Cholesterol","volume":"110","author":"Hung","year":"2016","journal-title":"Biophys. J."},{"key":"10.1016\/j.bpj.2026.07.026_bib58","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1529\/biophysj.106.097345","article-title":"Ergosterol in POPC membranes: physical properties and comparison with structurally similar sterols","volume":"92","author":"Hsueh","year":"2007","journal-title":"Biophys. J."},{"key":"10.1016\/j.bpj.2026.07.026_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbamem.2024.184385","article-title":"A molecular mechanism for how pressure induces interdigitation of phospholipid bilayer membranes","volume":"1866","author":"Goto","year":"2024","journal-title":"Biochim. Biophys. Acta. Biomembr."},{"key":"10.1016\/j.bpj.2026.07.026_bib60","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1016\/j.bbamem.2008.01.015","article-title":"Protein modulation of lipids, and vice-versa, in membranes","volume":"1778","author":"Marsh","year":"2008","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bpj.2026.07.026_bib61","doi-asserted-by":"crossref","first-page":"1940","DOI":"10.1016\/j.bbamem.2011.04.004","article-title":"Effect of hydrophobic mismatch and interdigitation on sterol\/sphingomyelin interaction in ternary bilayer membranes","volume":"1808","author":"Jaikishan","year":"2011","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bpj.2026.07.026_bib62","doi-asserted-by":"crossref","first-page":"2586","DOI":"10.1016\/j.cell.2025.02.034","article-title":"Cell membranes sustain phospholipid imbalance via cholesterol asymmetry","volume":"188","author":"Doktorova","year":"2025","journal-title":"Cell"},{"key":"10.1016\/j.bpj.2026.07.026_bib63","doi-asserted-by":"crossref","first-page":"3452","DOI":"10.1016\/j.bpj.2024.08.019","article-title":"Several common methods of making vesicles (except an emulsion method) capture intended lipid ratios","volume":"123","author":"Weakly","year":"2024","journal-title":"Biophys. J."},{"key":"10.1016\/j.bpj.2026.07.026_bib64","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/j.bpj.2015.12.019","article-title":"Glucosylceramide reorganizes cholesterol-containing domains in a fluid phospholipid membrane","volume":"110","author":"Varela","year":"2016","journal-title":"Biophys. J."}],"container-title":["Biophysical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006349526005370?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006349526005370?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T15:21:08Z","timestamp":1788276068000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006349526005370"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":64,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["S0006349526005370"],"URL":"https:\/\/doi.org\/10.1016\/j.bpj.2026.07.026","relation":{},"ISSN":["0006-3495"],"issn-type":[{"value":"0006-3495","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Coupling between sterol and sphingolipid structure in ordered membrane domains","name":"articletitle","label":"Article Title"},{"value":"Biophysical Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bpj.2026.07.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc. on behalf of Biophysical Society.","name":"copyright","label":"Copyright"}]}}