{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T23:23:44Z","timestamp":1790378624647,"version":"4.1.0"},"reference-count":94,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2007,10,1]],"date-time":"2007-10-01T00:00:00Z","timestamp":1191196800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Best Practice & Research Clinical Obstetrics & Gynaecology"],"published-print":{"date-parts":[[2007,10]]},"DOI":"10.1016\/j.bpobgyn.2007.03.003","type":"journal-article","created":{"date-parts":[[2007,4,19]],"date-time":"2007-04-19T11:35:48Z","timestamp":1176982548000},"page":"807-819","source":"Crossref","is-referenced-by-count":21,"title":["Myometrial function in prematurity"],"prefix":"10.1016","volume":"21","author":[{"given":"Andrew M.","family":"Blanks","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anatoly","family":"Shmygol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Thornton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bpobgyn.2007.03.003_bib1","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1007\/BF00668731","article-title":"Structure of the human uterus wall","volume":"205","author":"Goerttler","year":"1968","journal-title":"Arch Gynakol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib2","first-page":"461","article-title":"Arrangement of smooth muscle in the human uterus","volume":"64","author":"Wetzstein","year":"1970","journal-title":"Verh Anat Ges"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib3","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1002\/ar.a.20274","article-title":"Three-dimensional fiber architecture of the nonpregnant human uterus determined ex vivo using magnetic resonance diffusion tensor imaging","volume":"288","author":"Weiss","year":"2006","journal-title":"Anat Rec A Discov Mol Cell Evol Biol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/aja.1001860102","article-title":"Histologic, morphometric, and immunocytochemical analysis of myometrial development in rats and mice: I. Normal development","volume":"186","author":"Brody","year":"1989","journal-title":"Am J Anat"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib5","first-page":"94","article-title":"Three-dimensional structure of the smooth muscle in the term-pregnant human uterus","volume":"93","author":"Young","year":"1999","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib6","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1172\/JCI116564","article-title":"Contractile elements and myosin light chain phosphorylation in myometrial tissue from nonpregnant and pregnant women","volume":"92","author":"Word","year":"1993","journal-title":"J Clin Invest"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib7","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0162-0134(86)80093-9","article-title":"Crystal structure of calmodulin","volume":"28","author":"Kretsinger","year":"1986","journal-title":"J Inorg Biochem"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib8","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1113\/jphysiol.1973.sp010301","article-title":"Excitation\u2013contraction coupling in voltage clamped uterine smooth muscle","volume":"233","author":"Mironneau","year":"1973","journal-title":"J Physiol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib9","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1016\/S0002-9378(99)70390-X","article-title":"Contractile activity, membrane potential, and cytoplasmic calcium in human uterine smooth muscle in the third trimester of pregnancy and during labor","volume":"181","author":"Parkington","year":"1999","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib10","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1111\/j.1469-7793.1998.803bg.x","article-title":"Properties of voltage-activated [Ca2+]i transients in single smooth muscle cells isolated from pregnant rat uterus","volume":"511","author":"Shmigol","year":"1998","journal-title":"J Physiol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib11","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1111\/j.1469-7793.1999.0769p.x","article-title":"Voltage-gated K+ currents in freshly isolated myocytes of the pregnant human myometrium","volume":"518","author":"Knock","year":"1999","journal-title":"J Physiol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib12","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/j.1469-7793.1999.229af.x","article-title":"Hyperpolarization and slowing of the rate of contraction in human uterus in pregnancy by prostaglandins E2 and f2alpha: involvement of the Na+ pump","volume":"514","author":"Parkington","year":"1999","journal-title":"J Physiol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib13","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1113\/eph8602181","article-title":"Potassium channels in the human myometrium","volume":"86","author":"Khan","year":"2001","journal-title":"Exp Physiol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib14","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/S0002-9378(97)70465-4","article-title":"Oxytocin enhances action potentials in pregnant human myometrium \u2013 a study with microelectrodes","volume":"177","author":"Nakao","year":"1997","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib15","first-page":"1207","article-title":"Contributions of inwardly rectifying K+ currents to repolarization assessed using mathematical models of human ventricular myocytes","volume":"364","author":"Fink","year":"2006","journal-title":"Philosophic Trans"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib16","doi-asserted-by":"crossref","first-page":"197","DOI":"10.2170\/jjphysiol.28.197","article-title":"Electrophysiological comparison between the longitudinal and circular muscles of the rat uterus during the estrous cycle and pregnancy","volume":"28","author":"Osa","year":"1978","journal-title":"Jpn J Physiol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib17","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1113\/jphysiol.1988.sp017066","article-title":"Induction of prolonged excitability in myometrium of pregnant guinea-pigs by prostaglandin F2 alpha","volume":"399","author":"Coleman","year":"1988","journal-title":"J Physiol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib18","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/0002-9378(94)90288-7","article-title":"Chloride and monovalent ion-selective cation currents activated by oxytocin in pregnant rat myometrial cells","volume":"171","author":"Arnaudeau","year":"1994","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib19","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1007\/s00424-003-1224-7","article-title":"Electrophysiological characterization and functional importance of calcium-activated chloride channel in rat uterine myocytes","volume":"448","author":"Jones","year":"2004","journal-title":"Pflugers Arch"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib20","doi-asserted-by":"crossref","first-page":"123","DOI":"10.2170\/jjphysiol.27.123","article-title":"Effects of ions and drugs on the negative afterpotential in the longitudinal muscle of pregnant rat myometrium","volume":"27","author":"Osa","year":"1977","journal-title":"Jpn J Physiol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib21","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1038\/384078a0","article-title":"K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current","volume":"384","author":"Barhanin","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib22","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1056\/NEJM199910073411504","article-title":"Molecular diagnosis of the inherited long-QT syndrome in a woman who died after near-drowning","volume":"341","author":"Ackerman","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib23","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1113\/jphysiol.1988.sp017065","article-title":"Gestational changes in the utilization of intracellularly stored calcium in the myometrium of guinea-pigs","volume":"399","author":"Coleman","year":"1988","journal-title":"J Physiol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib24","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1111\/j.1469-7793.2000.00785.x","article-title":"Changes in the mechanisms involved in uterine contractions during pregnancy in guinea-pigs","volume":"523","author":"Coleman","year":"2000","journal-title":"J Physiol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib25","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/S0002-9378(99)70580-6","article-title":"Intracellular calcium stores and agonist-induced contractions in isolated human myometrium","volume":"181","author":"Luckas","year":"1999","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib26","first-page":"201","article-title":"Pharmacomechanical coupling: the role of calcium, G-proteins, kinases and phosphatases","volume":"134","author":"Somlyo","year":"1999","journal-title":"Rev Physiol Biochem Pharmacol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib27","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1007\/s004240100668","article-title":"The effects of inhibiting Rho-associated kinase with Y-27632 on force and intracellular calcium in human myometrium","volume":"443","author":"Kupittayanant","year":"2001","journal-title":"Pflugers Arch"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib28","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/S0002-9378(03)00925-6","article-title":"Effect of an oxytocin receptor antagonist and rho kinase inhibitor on the [Ca++]i sensitivity of human myometrium","volume":"190","author":"Woodcock","year":"2004","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib29","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1016\/j.ajog.2006.03.099","article-title":"Prostaglandin F(2alpha) increases the sensitivity of the contractile proteins to Ca(2+) in human myometrium","volume":"195","author":"Woodcock","year":"2006","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib30","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1126\/science.273.5272.245","article-title":"Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)","volume":"273","author":"Kimura","year":"1996","journal-title":"Science"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib31","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1006\/bbrc.2000.2290","article-title":"Up-regulation of p21- and RhoA-activated protein kinases in human pregnant myometrium","volume":"269","author":"Moore","year":"2000","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib32","doi-asserted-by":"crossref","first-page":"9897","DOI":"10.1074\/jbc.275.14.9897","article-title":"Agonists trigger G protein-mediated activation of the CPI-17 inhibitor phosphoprotein of myosin light chain phosphatase to enhance vascular smooth muscle contractility","volume":"275","author":"Kitazawa","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib33","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1038\/sj.bjp.0705552","article-title":"Possible role of the protein kinase C\/CPI-17 pathway in the augmented contraction of human myometrium after gestation","volume":"140","author":"Ozaki","year":"2003","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib34","first-page":"436","article-title":"Control of myometrial contractility: role and regulation of gap junctions","volume":"10","author":"Garfield","year":"1988","journal-title":"Oxford Rev Reproduct Biol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib35","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1126\/science.929182","article-title":"Gap junctions: their presence and necessity in myometrium during parturition","volume":"198","author":"Garfield","year":"1977","journal-title":"Science"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib36","doi-asserted-by":"crossref","first-page":"C168","DOI":"10.1152\/ajpcell.1978.235.5.C168","article-title":"Possible role of gap junctions in activation of myometrium during parturition","volume":"235","author":"Garfield","year":"1978","journal-title":"Am J Physiol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib37","doi-asserted-by":"crossref","first-page":"C130","DOI":"10.1152\/ajpcell.1989.256.1.C130","article-title":"Improved propagation in myometrium associated with gap junctions during parturition","volume":"256","author":"Miller","year":"1989","journal-title":"Am J Physiol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib38","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1095\/biolreprod46.3.358","article-title":"Effects of antiprogesterones on myometrial cell-to-cell coupling in pregnant guinea pigs","volume":"46","author":"Sakai","year":"1992","journal-title":"Biol Reprod"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib39","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1139\/y92-045","article-title":"Intracellular cyclic AMP concentration modulates gap junction permeability in parturient rat myometrium","volume":"70","author":"Sakai","year":"1992","journal-title":"Can J Physiol Pharmacol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib40","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1016\/S0002-9378(11)91699-8","article-title":"Studies of connexin 43 and cell-to-cell coupling in cultured human uterine smooth muscle","volume":"167","author":"Sakai","year":"1992","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib41","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/S0002-9378(11)91432-X","article-title":"Modulation of cell-to-cell coupling between myometrial cells of the human uterus during pregnancy","volume":"167","author":"Sakai","year":"1992","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib42","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1085\/jgp.80.3.353","article-title":"Improved electrical coupling in uterine smooth muscle is associated with increased numbers of gap junctions at parturition","volume":"80","author":"Sims","year":"1982","journal-title":"J Gen Physiol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib43","doi-asserted-by":"crossref","first-page":"C411","DOI":"10.1152\/ajpcell.1986.251.3.C411","article-title":"Evidence for physiological regulation of myometrial gap junction permeability","volume":"251","author":"Cole","year":"1986","journal-title":"Am J Physiol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib44","doi-asserted-by":"crossref","first-page":"C20","DOI":"10.1152\/ajpcell.1985.249.1.C20","article-title":"Gap junctions and direct intercellular communication between rat uterine smooth muscle cells","volume":"249","author":"Cole","year":"1985","journal-title":"Am J Physiol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib45","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1016\/S0006-3495(96)79332-3","article-title":"Voltage-clamp studies of gap junctions between uterine muscle cells during term and preterm labor","volume":"71","author":"Miyoshi","year":"1996","journal-title":"Biophys J"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib46","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/S0002-9378(98)70443-0","article-title":"Gap junction currents in cultured muscle cells from human myometrium","volume":"178","author":"Miyoshi","year":"1998","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib47","doi-asserted-by":"crossref","first-page":"C1559","DOI":"10.1152\/ajpcell.2001.281.5.C1559","article-title":"Heterotypic gap junction channel formation between heteromeric and homomeric Cx40 and Cx43 connexons","volume":"281","author":"Cottrell","year":"2001","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib48","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/S0002-9378(11)91453-7","article-title":"An immunochemical and immunocytologic study of the increase in myometrial gap junctions (and connexin 43) in rats and humans during pregnancy","volume":"167","author":"Tabb","year":"1992","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib49","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1210\/endo.137.5.8612484","article-title":"Connexin-26 and connexin-43 are differentially expressed and regulated in the rat myometrium throughout late pregnancy and with the onset of labor","volume":"137","author":"Orsino","year":"1996","journal-title":"Endocrinology"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib50","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0171-9335(98)80040-X","article-title":"Identification of two further gap-junctional proteins, connexin40 and connexin45, in human myometrial smooth muscle cells at term","volume":"75","author":"Kilarski","year":"1998","journal-title":"Eur J Cell Biol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib51","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1002\/jemt.1126","article-title":"Multiple connexins localized to individual gap-junctional plaques in human myometrial smooth muscle","volume":"54","author":"Kilarski","year":"2001","journal-title":"Microsc Res Tech"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib52","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1242\/jcs.02892","article-title":"Ablation of connexin43 in uterine smooth muscle cells of the mouse causes delayed parturition","volume":"119","author":"Doring","year":"2006","journal-title":"J Cell Sci"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib53","doi-asserted-by":"crossref","first-page":"2380","DOI":"10.1210\/endo.132.6.8389279","article-title":"Increased expression of connexin-43 in the rat myometrium during labor is associated with an increase in the plasma estrogen:progesterone ratio","volume":"132","author":"Lye","year":"1993","journal-title":"Endocrinology"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib54","doi-asserted-by":"crossref","first-page":"5398","DOI":"10.1210\/endo.138.12.5624","article-title":"Expression of connexin-43 and connexin-26 in the rat myometrium during pregnancy and labor is differentially regulated by mechanical and hormonal signals","volume":"138","author":"Ou","year":"1997","journal-title":"Endocrinology"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib55","first-page":"1705","article-title":"The differential expression of myometrial connexin-43, cyclooxygenase-1 and -2, and Gs alpha proteins in the upper and lower segments of the human uterus during pregnancy and labor","volume":"84","author":"Sparey","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"issue":"supplement 20","key":"10.1016\/j.bpobgyn.2007.03.003_bib56","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/S1470-0328(03)00024-7","article-title":"The role of oxytocin in parturition","volume":"110","author":"Blanks","year":"2003","journal-title":"BJOG"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib57","first-page":"2098","article-title":"Multiple G proteins and phospholipase C isoforms in human myometrial cells: implication for oxytocin action","volume":"81","author":"Phaneuf","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib58","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0898-6568(97)00097-1","article-title":"Evidence for the involvement of several intracellular domains in the coupling of oxytocin receptor to G alpha(q\/11)","volume":"10","author":"Qian","year":"1998","journal-title":"Cell Signal"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib59","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1210\/endo.136.4.7895660","article-title":"Oxytocin stimulates myometrial guanosine triphosphatase and phospholipase-C activities via coupling to G alpha q\/11","volume":"136","author":"Ku","year":"1995","journal-title":"Endocrinology"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib60","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/BF00374751","article-title":"Oxytocin mobilizes calcium from a unique heparin-sensitive and thapsigargin-sensitive store in single myometrial cells from pregnant rats","volume":"428","author":"Arnaudeau","year":"1994","journal-title":"Pflugers Arch"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib61","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1042\/bj3150739","article-title":"Oxytocin receptor couples to the 80 kDa Gh alpha family protein in human myometrium","volume":"315","author":"Baek","year":"1996","journal-title":"Biochem J"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib62","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1038\/312315a0","article-title":"Inositol trisphosphate, a novel second messenger in cellular signal transduction","volume":"312","author":"Berridge","year":"1984","journal-title":"Nature"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib63","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.ceca.2004.02.001","article-title":"Stimulation of intracellular Ca2+ oscillations by diacylglycerol in human myometrial cells","volume":"36","author":"Shlykov","year":"2004","journal-title":"Cell Calcium"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib64","first-page":"2104","article-title":"Fluprostenol activates phospholipase C and Ca2+ mobilization in human myometrial cells","volume":"81","author":"Carrasco","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib65","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1016\/S0002-9378(88)80182-0","article-title":"A role for phosphoinositide hydrolysis in human uterine smooth muscle during parturition","volume":"159","author":"Schrey","year":"1988","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib66","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0090-6980(93)90052-9","article-title":"Prostaglandin F2 alpha stimulates inositol phosphate production in human pregnant myometrium","volume":"45","author":"Maka","year":"1993","journal-title":"Prostaglandins"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib67","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1210\/jcem-71-5-1243","article-title":"Regulation of intracellular free calcium in human myometrial cells by prostaglandin F2 alpha: comparison with oxytocin","volume":"71","author":"Molnar","year":"1990","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib68","doi-asserted-by":"crossref","first-page":"2632","DOI":"10.1016\/S0021-9258(17)41991-0","article-title":"Cloning and expression of a cDNA for the human prostanoid FP receptor","volume":"269","author":"Abramovitz","year":"1994","journal-title":"J Biol Chem"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib69","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1093\/molehr\/gah158","article-title":"Identification and localization of prostaglandin E2 receptors in upper and lower segment human myometrium during pregnancy","volume":"11","author":"Astle","year":"2005","journal-title":"Mol Hum Reprod"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib70","first-page":"205","article-title":"International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes","volume":"46","author":"Coleman","year":"1994","journal-title":"Pharmacol Rev"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib71","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0005-2760(95)00146-4","article-title":"Molecular mechanisms of diverse actions of prostanoid receptors","volume":"1259","author":"Negishi","year":"1995","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib72","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1111\/j.1432-1033.1995.tb20223.x","article-title":"Splice variants of the human EP3 receptor for prostaglandin E2","volume":"228","author":"Schmid","year":"1995","journal-title":"Eur J Biochem"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib73","doi-asserted-by":"crossref","first-page":"26767","DOI":"10.1016\/S0021-9258(19)74379-8","article-title":"Cloning and expression of a cDNA for the human prostaglandin E receptor EP1 subtype","volume":"268","author":"Funk","year":"1993","journal-title":"J Biol Chem"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib74","first-page":"869","article-title":"Molecular cloning and expression of multiple isoforms of human prostaglandin E receptor EP3 subtype generated by alternative messenger RNA splicing: multiple second messenger systems and tissue-specific distributions","volume":"48","author":"Kotani","year":"1995","journal-title":"Mol Pharmacol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib75","doi-asserted-by":"crossref","first-page":"11873","DOI":"10.1016\/S0021-9258(17)32654-6","article-title":"Cloning, functional expression, and characterization of the human prostaglandin E2 receptor EP2 subtype","volume":"269","author":"Bastien","year":"1994","journal-title":"J Biol Chem"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib76","first-page":"213","article-title":"Cloning of a novel human prostaglandin receptor with characteristics of the pharmacologically defined EP2 subtype","volume":"46","author":"Regan","year":"1994","journal-title":"Mol Pharmacol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib77","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1006\/bbrc.1997.7397","article-title":"The prostaglandin E2 and F2 alpha receptor genes are expressed in human myometrium and are down-regulated during pregnancy","volume":"238","author":"Matsumoto","year":"1997","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib78","first-page":"89","article-title":"Prostaglandin receptors in lower segment myometrium during gestation and labor","volume":"93","author":"Brodt-Eppley","year":"1999","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib79","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0952-3278(03)00113-3","article-title":"Expression of prostanoid receptors in human lower segment pregnant myometrium","volume":"69","author":"Leonhardt","year":"2003","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib80","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/S1071-5576(03)00007-8","article-title":"EP3-2 receptor mRNA expression is reduced and EP3-6 receptor mRNA expression is increased in gravid human myometrium","volume":"10","author":"Wing","year":"2003","journal-title":"J Soc Gynecol Investig"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib81","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1016\/S0002-9378(98)70022-5","article-title":"Regional variations in contractile responses to prostaglandins and prostanoid receptor messenger ribonucleic acid in pregnant baboon uterus","volume":"179","author":"Smith","year":"1998","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib82","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1111\/j.1476-5381.1993.tb12832.x","article-title":"In vitro characterization of prostanoid receptors on human myometrium at term pregnancy","volume":"108","author":"Senior","year":"1993","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib83","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1093\/molehr\/gal005","article-title":"Anti-inflammatory and relaxatory effects of prostaglandin E2 in myometrial smooth muscle","volume":"12","author":"Slater","year":"2006","journal-title":"Mol Hum Reprod"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib84","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1113\/eph8602179","article-title":"Hormones and calcium: mechanisms controlling uterine smooth muscle contractile activity. The Litchfield Lecture","volume":"86","author":"Sanborn","year":"2001","journal-title":"Exp Physiol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib85","first-page":"514","article-title":"Endocrine and paracrine regulation of birth at term and preterm","volume":"21","author":"Challis","year":"2000","journal-title":"Endocr Rev"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib86","first-page":"435","article-title":"Parturition: activation of stimulatory pathways or loss of uterine quiescence?","volume":"395","author":"Lopez Bernal","year":"1995","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib87","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/BF01753559","article-title":"Myosin light chain phosphorylation in intact rat uterine smooth muscle. Role of calcium and cyclic AMP","volume":"7","author":"Dokhac","year":"1986","journal-title":"J Muscle Res Cell Motil"},{"issue":"supplement 20","key":"10.1016\/j.bpobgyn.2007.03.003_bib88","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1046\/j.1471-0528.2003.00023.x","article-title":"Mechanisms of labour \u2013 biochemical aspects","volume":"110","author":"Lopez Bernal","year":"2003","journal-title":"BJOG"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib89","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1677\/joe.0.1640021","article-title":"Adenylyl cyclase isoforms in pregnant and non-pregnant human myometrium","volume":"164","author":"Price","year":"2000","journal-title":"J Endocrinol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib90","doi-asserted-by":"crossref","first-page":"C976","DOI":"10.1152\/ajpcell.1993.265.4.C976","article-title":"Calcium-activated K+ channels as modulators of human myometrial contractile activity","volume":"265","author":"Anwer","year":"1993","journal-title":"Am J Physiol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib91","doi-asserted-by":"crossref","first-page":"C1049","DOI":"10.1152\/ajpcell.1992.263.5.C1049","article-title":"Ca(2+)-activated K+ channels in pregnant rat myometrium: modulation by a beta-adrenergic agent","volume":"263","author":"Anwer","year":"1992","journal-title":"Am J Physiol"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib92","doi-asserted-by":"crossref","first-page":"18023","DOI":"10.1074\/jbc.273.29.18023","article-title":"Phosphorylation of serine 1105 by protein kinase A inhibits phospholipase Cbeta3 stimulation by Galphaq","volume":"273","author":"Yue","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib93","doi-asserted-by":"crossref","first-page":"2265","DOI":"10.1210\/endo.139.5.5963","article-title":"Evidence for inhibition by protein kinase A of receptor\/G alpha(q)\/phospholipase C (PLC) coupling by a mechanism not involving PLCbeta2","volume":"139","author":"Dodge","year":"1998","journal-title":"Endocrinology"},{"key":"10.1016\/j.bpobgyn.2007.03.003_bib94","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/BF01076564","article-title":"Phosphorylation and partial sequence of pregnant sheep myometrium myosin light chain kinase","volume":"149\u2013150","author":"Pato","year":"1995","journal-title":"Mol Cell Biochem"}],"container-title":["Best Practice & Research Clinical Obstetrics & Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521693407000454?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521693407000454?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,2,13]],"date-time":"2024-02-13T13:56:29Z","timestamp":1707832589000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521693407000454"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,10]]},"references-count":94,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007,10]]}},"alternative-id":["S1521693407000454"],"URL":"https:\/\/doi.org\/10.1016\/j.bpobgyn.2007.03.003","relation":{},"ISSN":["1521-6934"],"issn-type":[{"value":"1521-6934","type":"print"}],"subject":[],"published":{"date-parts":[[2007,10]]}}}