{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,26]],"date-time":"2025-07-26T09:11:29Z","timestamp":1753521089940},"reference-count":96,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Best Practice &amp; Research Clinical Obstetrics &amp; Gynaecology"],"published-print":{"date-parts":[[2010,2]]},"DOI":"10.1016\/j.bpobgyn.2009.08.002","type":"journal-article","created":{"date-parts":[[2009,10,28]],"date-time":"2009-10-28T04:26:22Z","timestamp":1256703982000},"page":"3-18","source":"Crossref","is-referenced-by-count":2,"title":["Cancer genetics and reproduction"],"prefix":"10.1016","volume":"24","author":[{"given":"Helen","family":"Hanson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shirley","family":"Hodgson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.bpobgyn.2009.08.002_bib1","first-page":"77","article-title":"Heredity and human cancer","volume":"77","author":"Knudson","year":"1974","journal-title":"Am J Pathol"},{"issue":"5182","key":"10.1016\/j.bpobgyn.2009.08.002_bib2","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1126\/science.7545954","article-title":"A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1","volume":"266","author":"Miki","year":"1994","journal-title":"Science"},{"issue":"6559","key":"10.1016\/j.bpobgyn.2009.08.002_bib3","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1038\/378789a0","article-title":"Identification of the breast cancer susceptibility gene BRCA2","volume":"378","author":"Wooster","year":"1995","journal-title":"Nature"},{"issue":"4985","key":"10.1016\/j.bpobgyn.2009.08.002_bib4","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1126\/science.1978757","article-title":"Germ Line P53 mutations in a familial syndrome of breast-cancer, sarcomas, and other neoplasms","volume":"250","author":"Malkin","year":"1990","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.bpobgyn.2009.08.002_bib5","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1038\/ng1959","article-title":"PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene","volume":"39","author":"Rahman","year":"2007","journal-title":"Nat Genet"},{"issue":"11","key":"10.1016\/j.bpobgyn.2009.08.002_bib6","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1038\/ng1902","article-title":"Truncating mutations in the fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles","volume":"38","author":"Seal","year":"2006","journal-title":"Nat Genet"},{"issue":"1","key":"10.1016\/j.bpobgyn.2009.08.002_bib7","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/ng879","article-title":"Low-penetrance susceptibility to breast cancer due to CHEK2 (\u2217)1100delC in noncarriers of BRCA1 or BRCA2 mutations","volume":"31","author":"Meijers-Heijboer","year":"2002","journal-title":"Nat Genet"},{"issue":"7148","key":"10.1016\/j.bpobgyn.2009.08.002_bib8","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1038\/nature05887","article-title":"Genome-wide association study identifies novel breast cancer susceptibility loci","volume":"447","author":"Easton","year":"2007","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.bpobgyn.2009.08.002_bib9","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/ng.90","article-title":"Multiple newly identified loci associated with prostate cancer susceptibility","volume":"40","author":"Eeles","year":"2008","journal-title":"Nat Genet"},{"issue":"3","key":"10.1016\/j.bpobgyn.2009.08.002_bib10","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1038\/ng.91","article-title":"Multiple loci identified in a genome-wide association study of prostate cancer","volume":"40","author":"Thomas","year":"2008","journal-title":"Nat Genet"},{"issue":"4","key":"10.1016\/j.bpobgyn.2009.08.002_bib11","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/S0002-9378(98)70476-4","article-title":"BRCA1, BRCA2, and hereditary nonpolyposis colorectal cancer gene mutations in an unselected ovarian cancer population: relationship to family history and implications for genetic testing","volume":"178","author":"Rubin","year":"1998","journal-title":"Am J Obstet Gynecol"},{"issue":"5","key":"10.1016\/j.bpobgyn.2009.08.002_bib12","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1086\/375033","article-title":"Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies","volume":"72","author":"Antoniou","year":"2003","journal-title":"Am J Hum Genet"},{"issue":"17","key":"10.1016\/j.bpobgyn.2009.08.002_bib13","doi-asserted-by":"crossref","first-page":"2260","DOI":"10.1001\/jama.283.17.2260","article-title":"Clinicopathologic features of BRCA-linked and sporadic ovarian cancer","volume":"283","author":"Boyd","year":"2000","journal-title":"J Am Med Assoc"},{"issue":"1 Pt 2","key":"10.1016\/j.bpobgyn.2009.08.002_bib14","doi-asserted-by":"crossref","first-page":"S8","DOI":"10.1006\/gyno.2002.6674","article-title":"Specific keynote: hereditary ovarian cancer: what we know","volume":"88","author":"Boyd","year":"2003","journal-title":"Gynecol Oncol"},{"issue":"3","key":"10.1016\/j.bpobgyn.2009.08.002_bib15","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1086\/301749","article-title":"Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium","volume":"62","author":"Ford","year":"1998","journal-title":"Am J Hum Genet"},{"issue":"3","key":"10.1016\/j.bpobgyn.2009.08.002_bib16","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1086\/318787","article-title":"Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer","volume":"68","author":"Risch","year":"2001","journal-title":"Am J Hum Genet"},{"issue":"2","key":"10.1016\/j.bpobgyn.2009.08.002_bib17","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1006\/gyno.2001.6279","article-title":"The clinical features of ovarian cancer in hereditary nonpolyposis colorectal cancer","volume":"82","author":"Watson","year":"2001","journal-title":"Gynecol Oncol"},{"issue":"2","key":"10.1016\/j.bpobgyn.2009.08.002_bib18","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1002\/(SICI)1097-0215(19990412)81:2<214::AID-IJC8>3.0.CO;2-L","article-title":"Cancer risk in mutation carriers of DNA-mismatch repair genes","volume":"81","author":"Aarnio","year":"1999","journal-title":"Int J Cancer"},{"issue":"4","key":"10.1016\/j.bpobgyn.2009.08.002_bib19","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1053\/gast.1996.v110.pm8612988","article-title":"Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis","volume":"110","author":"Vasen","year":"1996","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.bpobgyn.2009.08.002_bib20","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1023\/A:1011590617833","article-title":"Cancer risk in mismatch repair gene mutation carriers","volume":"1","author":"Watson","year":"2001","journal-title":"Fam Cancer"},{"issue":"43","key":"10.1016\/j.bpobgyn.2009.08.002_bib21","doi-asserted-by":"crossref","first-page":"5864","DOI":"10.1038\/sj.onc.1209874","article-title":"The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability","volume":"25","author":"Gudmundsdottir","year":"2006","journal-title":"Oncogene"},{"issue":"4","key":"10.1016\/j.bpobgyn.2009.08.002_bib22","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1086\/302583","article-title":"The contribution of germline BRCA1 and BRCA2 mutations to familial ovarian cancer: no evidence for other ovarian cancer-susceptibility genes","volume":"65","author":"Gayther","year":"1999","journal-title":"Am J Hum Genet"},{"issue":"12","key":"10.1016\/j.bpobgyn.2009.08.002_bib23","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1002\/humu.20599","article-title":"Contribution of BRCA1 and BRCA2 mutations to inherited ovarian cancer","volume":"28","author":"Ramus","year":"2007","journal-title":"Hum Mutat"},{"issue":"16","key":"10.1016\/j.bpobgyn.2009.08.002_bib24","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1056\/NEJM199704173361602","article-title":"Contribution of BRCA1 mutations to ovarian cancer","volume":"336","author":"Stratton","year":"1997","journal-title":"N Engl J Med"},{"issue":"12","key":"10.1016\/j.bpobgyn.2009.08.002_bib25","doi-asserted-by":"crossref","first-page":"2807","DOI":"10.1002\/cncr.21536","article-title":"BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases","volume":"104","author":"Pal","year":"2005","journal-title":"Cancer"},{"issue":"1","key":"10.1016\/j.bpobgyn.2009.08.002_bib26","first-page":"265","article-title":"Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium","volume":"56","author":"Easton","year":"1995","journal-title":"Am J Hum Genet"},{"issue":"15","key":"10.1016\/j.bpobgyn.2009.08.002_bib27","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1093\/jnci\/91.15.1310","article-title":"Cancer risks in BRCA2 mutation carriers. The breast cancer linkage consortium","volume":"91","year":"1999","journal-title":"J Natl Cancer Inst"},{"issue":"1","key":"10.1016\/j.bpobgyn.2009.08.002_bib28","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/ng0197-103","article-title":"Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene","volume":"15","author":"Gayther","year":"1997","journal-title":"Nat Genet"},{"issue":"4","key":"10.1016\/j.bpobgyn.2009.08.002_bib30","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/j.ajhg.2008.02.008","article-title":"Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers","volume":"82","author":"Antoniou","year":"2008","journal-title":"Am J Hum Genet"},{"issue":"2","key":"10.1016\/j.bpobgyn.2009.08.002_bib31","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1006\/gyno.1997.4844","article-title":"High frequency of BRCA1 and BRCA2 germline mutations in Ashkenazi Jewish ovarian cancer patients, regardless of family history","volume":"67","author":"Beller","year":"1997","journal-title":"Gynecol Oncol"},{"issue":"3","key":"10.1016\/j.bpobgyn.2009.08.002_bib32","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1056\/NEJM199601183340302","article-title":"Germ-line BRCA1 mutations in Jewish and non-Jewish women with early-onset breast cancer","volume":"334","author":"Fitzgerald","year":"1996","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.bpobgyn.2009.08.002_bib33","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1038\/ng0596-126","article-title":"Recurrent BRCA2 6174delT mutations in Ashkenazi Jewish women affected by breast cancer","volume":"13","author":"Neuhausen","year":"1996","journal-title":"Nat Genet"},{"issue":"20","key":"10.1016\/j.bpobgyn.2009.08.002_bib34","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1056\/NEJM199705153362001","article-title":"The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews","volume":"336","author":"Struewing","year":"1997","journal-title":"N Engl J Med"},{"issue":"Suppl. 6","key":"10.1016\/j.bpobgyn.2009.08.002_bib35","doi-asserted-by":"crossref","first-page":"vi93","DOI":"10.1093\/annonc\/mdm234","article-title":"Founder mutations in BRCA1 and BRCA2 genes","volume":"18","author":"Ferla","year":"2007","journal-title":"Ann Oncol"},{"issue":"19","key":"10.1016\/j.bpobgyn.2009.08.002_bib36","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1056\/NEJM199611073351901","article-title":"Clinical and pathological features of ovarian cancer in women with germ-line mutations of BRCA1","volume":"335","author":"Rubin","year":"1996","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.bpobgyn.2009.08.002_bib37","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1097\/01.pgp.0000101083.35393.cd","article-title":"Histopathology, FIGO stage, and BRCA mutation status of ovarian cancers from the Gilda Radner Familial Ovarian Cancer Registry","volume":"23","author":"Werness","year":"2004","journal-title":"Int J Gynecol Pathol"},{"issue":"22","key":"10.1016\/j.bpobgyn.2009.08.002_bib38","doi-asserted-by":"crossref","first-page":"4222","DOI":"10.1200\/JCO.2003.04.131","article-title":"Fallopian tube and primary peritoneal carcinomas associated with BRCA mutations","volume":"21","author":"Levine","year":"2003","journal-title":"J\u00a0Clin Oncol"},{"issue":"6","key":"10.1016\/j.bpobgyn.2009.08.002_bib39","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1086\/302671","article-title":"The genetic epidemiology of early-onset epithelial ovarian cancer: a population-based study","volume":"65","author":"Stratton","year":"1999","journal-title":"Am J Hum Genet"},{"issue":"9","key":"10.1016\/j.bpobgyn.2009.08.002_bib40","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1002\/cncr.11310","article-title":"Improved survival in women with BRCA-associated ovarian carcinoma","volume":"97","author":"Cass","year":"2003","journal-title":"Cancer"},{"issue":"4","key":"10.1016\/j.bpobgyn.2009.08.002_bib41","first-page":"868","article-title":"Survival in familial, BRCA1-associated, and BRCA2-associated epithelial ovarian cancer. United Kingdom Coordinating Committee for Cancer Research (UKCCCR) Familial Ovarian Cancer Study Group","volume":"59","author":"Pharoah","year":"1999","journal-title":"Cancer Res"},{"issue":"2","key":"10.1016\/j.bpobgyn.2009.08.002_bib42","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1200\/JCO.1998.16.2.397","article-title":"Survival of BRCA1 breast and ovarian cancer patients: a population-based study from southern Sweden","volume":"16","author":"Johannsson","year":"1998","journal-title":"J Clin Oncol"},{"issue":"4","key":"10.1016\/j.bpobgyn.2009.08.002_bib43","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1038\/sj.ejhg.5201584","article-title":"Phenotypic and genotypic heterogeneity in the Lynch syndrome: diagnostic, surveillance and management implications","volume":"14","author":"Lynch","year":"2006","journal-title":"Eur J Hum Genet"},{"issue":"6","key":"10.1016\/j.bpobgyn.2009.08.002_bib44","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/S0016-5085(99)70510-X","article-title":"New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC","volume":"116","author":"Vasen","year":"1999","journal-title":"Gastroenterology"},{"issue":"5","key":"10.1016\/j.bpobgyn.2009.08.002_bib45","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1007\/BF02053699","article-title":"The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC)","volume":"34","author":"Vasen","year":"1991","journal-title":"Dis Colon Rectum"},{"issue":"6","key":"10.1016\/j.bpobgyn.2009.08.002_bib46","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1200\/JCO.2003.04.060","article-title":"Role of DNA mismatch repair defects in the pathogenesis of human cancer","volume":"21","author":"Peltomaki","year":"2003","journal-title":"J Clin Oncol"},{"issue":"4\u20135","key":"10.1016\/j.bpobgyn.2009.08.002_bib47","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1155\/2004\/305058","article-title":"Mutations associated with HNPCC predisposition \u2013 update of ICG-HNPCC\/INSiGHT mutation database","volume":"20","author":"Peltomaki","year":"2004","journal-title":"Dis Markers"},{"issue":"2","key":"10.1016\/j.bpobgyn.2009.08.002_bib48","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1053\/j.gastro.2008.04.026","article-title":"The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations","volume":"135","author":"Senter","year":"2008","journal-title":"Gastroenterology"},{"issue":"3","key":"10.1016\/j.bpobgyn.2009.08.002_bib49","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1097\/01.AOG.0000154885.44002.ae","article-title":"Gynecologic cancer as a \u201csentinel cancer\u201d for women with hereditary nonpolyposis colorectal cancer syndrome","volume":"105","author":"Lu","year":"2005","journal-title":"Obstet Gynecol"},{"issue":"6","key":"10.1016\/j.bpobgyn.2009.08.002_bib50","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1136\/jmg.2007.048991","article-title":"Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer)","volume":"44","author":"Vasen","year":"2007","journal-title":"J Med Genet"},{"issue":"3","key":"10.1016\/j.bpobgyn.2009.08.002_bib51","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1056\/NEJMoa052627","article-title":"Prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch syndrome","volume":"354","author":"Schmeler","year":"2006","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.bpobgyn.2009.08.002_bib52","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1093\/hmg\/6.1.105","article-title":"Cancer risk associated with germline DNA mismatch repair gene mutations","volume":"6","author":"Dunlop","year":"1997","journal-title":"Hum Mol Genet"},{"issue":"2","key":"10.1016\/j.bpobgyn.2009.08.002_bib53","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s10689-007-9164-6","article-title":"Gene-related cancer spectrum in families with hereditary non-polyposis colorectal cancer (HNPCC)","volume":"7","author":"Geary","year":"2008","journal-title":"Fam Cancer"},{"issue":"2","key":"10.1016\/j.bpobgyn.2009.08.002_bib54","first-page":"97","article-title":"A common MSH2 mutation in English and North American HNPCC families: origin, phenotypic expression, and sex specific differences in colorectal cancer","volume":"36","author":"Froggatt","year":"1999","journal-title":"J Med Genet"},{"issue":"6","key":"10.1016\/j.bpobgyn.2009.08.002_bib55","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1136\/jmg.2004.024299","article-title":"Risk of colorectal and endometrial cancer for carriers of mutations of the hMLH1 and hMSH2 gene: correction for ascertainment","volume":"42","author":"Quehenberger","year":"2005","journal-title":"Journal of Medical Genetics"},{"issue":"1","key":"10.1016\/j.bpobgyn.2009.08.002_bib56","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1002\/ijc.2910460108","article-title":"The tumour spectrum in hereditary non-polyposis colorectal cancer: a study of 24 kindreds in the Netherlands","volume":"46","author":"Vasen","year":"1990","journal-title":"Int J Cancer"},{"issue":"2","key":"10.1016\/j.bpobgyn.2009.08.002_bib57","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1038\/13773","article-title":"Familial endometrial cancer in female carriers of MSH6 germline mutations","volume":"23","author":"Wijnen","year":"1999","journal-title":"Nat Genet"},{"issue":"1","key":"10.1016\/j.bpobgyn.2009.08.002_bib58","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1053\/j.gastro.2004.03.068","article-title":"Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance","volume":"127","author":"Hendriks","year":"2004","journal-title":"Gastroenterology"},{"issue":"33","key":"10.1016\/j.bpobgyn.2009.08.002_bib59","doi-asserted-by":"crossref","first-page":"5158","DOI":"10.1200\/JCO.2007.10.8597","article-title":"Prospective determination of prevalence of Lynch syndrome in young women with endometrial cancer","volume":"25","author":"Lu","year":"2007","journal-title":"J Clin Onc"},{"issue":"23","key":"10.1016\/j.bpobgyn.2009.08.002_bib60","doi-asserted-by":"crossref","first-page":"4364","DOI":"10.1200\/JCO.2003.04.094","article-title":"Toward new strategies to select young endometrial cancer patients for mismatch repair gene mutation analysis","volume":"21","author":"Berends","year":"2003","journal-title":"Am J Clin Oncol"},{"issue":"5","key":"10.1016\/j.bpobgyn.2009.08.002_bib61","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1093\/hmg\/8.5.823","article-title":"Mismatch repair gene defects contribute to the genetic basis of double primary cancers of the colorectum and endometrium","volume":"8","author":"Millar","year":"1999","journal-title":"Hum Mol Genet"},{"issue":"2","key":"10.1016\/j.bpobgyn.2009.08.002_bib62","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.ygyno.2004.05.006","article-title":"Synchronous primary cancers of the endometrium and ovary: a single institution review of 84 cases","volume":"94","author":"Soliman","year":"2004","journal-title":"Gynecol Oncol"},{"issue":"1","key":"10.1016\/j.bpobgyn.2009.08.002_bib63","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1097\/00003081-199803000-00023","article-title":"Familial endometrial adenocarcinoma","volume":"41","author":"Sandles","year":"1998","journal-title":"Clin Obstet Gynecol"},{"issue":"21","key":"10.1016\/j.bpobgyn.2009.08.002_bib64","doi-asserted-by":"crossref","first-page":"4609","DOI":"10.1200\/JCO.2005.06.055","article-title":"Molecular analysis of familial endometrial carcinoma: a manifestation of hereditary nonpolyposis colorectal cancer or a separate syndrome?","volume":"23","author":"Ollikainen","year":"2005","journal-title":"J Clin Oncol"},{"issue":"6","key":"10.1016\/j.bpobgyn.2009.08.002_bib65","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1053\/gast.2000.20228","article-title":"Very high risk of cancer in familial Peutz-Jeghers syndrome","volume":"119","author":"Giardiello","year":"2000","journal-title":"Gastroenterology"},{"issue":"10","key":"10.1016\/j.bpobgyn.2009.08.002_bib66","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.1158\/1078-0432.CCR-06-0083","article-title":"Frequency and spectrum of cancers in the Peutz-Jeghers syndrome","volume":"12","author":"Hearle","year":"2006","journal-title":"Clin Cancer Res"},{"issue":"7","key":"10.1016\/j.bpobgyn.2009.08.002_bib67","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1053\/j.gastro.2004.03.014","article-title":"Relative frequency and morphology of cancers in STK11 mutation carriers","volume":"126","author":"Lim","year":"2004","journal-title":"Gastroenterology"},{"issue":"7","key":"10.1016\/j.bpobgyn.2009.08.002_bib68","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1002\/1097-0142(19821001)50:7<1384::AID-CNCR2820500726>3.0.CO;2-5","article-title":"Ovarian sex cord tumor with annular tubules: review of 74 cases including 27 with Peutz-Jeghers syndrome and four with adenoma malignum of the cervix","volume":"50","author":"Young","year":"1982","journal-title":"Cancer"},{"issue":"6","key":"10.1016\/j.bpobgyn.2009.08.002_bib69","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1136\/jmg.30.6.460","article-title":"Complications of the naevoid basal cell carcinoma syndrome: results of a population based study","volume":"30","author":"Evans","year":"1993","journal-title":"J Med Genet"},{"issue":"5","key":"10.1016\/j.bpobgyn.2009.08.002_bib70","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1053\/j.seminoncol.2007.07.009","article-title":"Cowden syndrome","volume":"34","author":"Gustafson","year":"2007","journal-title":"Semin Oncol"},{"issue":"5","key":"10.1016\/j.bpobgyn.2009.08.002_bib71","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1186\/bcr1750","article-title":"Breast cancer risk-assessment models","volume":"9","author":"Evans","year":"2007","journal-title":"Breast Cancer Res"},{"issue":"7","key":"10.1016\/j.bpobgyn.2009.08.002_bib72","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1136\/jmg.2007.056556","article-title":"Predicting the likelihood of carrying a BRCA1 or BRCA2 mutation: validation of BOADICEA, BRCAPRO, IBIS, Myriad and the Manchester scoring system using data from UK genetics clinics","volume":"45","author":"Antoniou","year":"2008","journal-title":"J Med Genet"},{"issue":"8","key":"10.1016\/j.bpobgyn.2009.08.002_bib73","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1038\/sj.bjc.6604305","article-title":"The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions","volume":"98","author":"Antoniou","year":"2008","journal-title":"Br J Cancer"},{"issue":"22","key":"10.1016\/j.bpobgyn.2009.08.002_bib74","first-page":"5248","article-title":"A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer","volume":"58","author":"Boland","year":"1998","journal-title":"Cancer Res"},{"issue":"23","key":"10.1016\/j.bpobgyn.2009.08.002_bib75","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1093\/jnci\/89.23.1758","article-title":"A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: meeting highlights and Bethesda guidelines","volume":"89","author":"Rodriguez-Bigas","year":"1997","journal-title":"J Natl Cancer Inst"},{"issue":"11","key":"10.1016\/j.bpobgyn.2009.08.002_bib76","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1056\/NEJM198703123161102","article-title":"The reduction in risk of ovarian cancer associated with oral-contraceptive use. The cancer and steroid hormone study of the centers for disease control and the National Institute of Child Health and Human Development","volume":"316","year":"1987","journal-title":"N Engl J Med"},{"issue":"7","key":"10.1016\/j.bpobgyn.2009.08.002_bib77","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1056\/NEJM199808133390702","article-title":"Oral contraceptives and the risk of hereditary ovarian cancer. Hereditary ovarian cancer clinical study Group","volume":"339","author":"Narod","year":"1998","journal-title":"N Engl J Med"},{"issue":"4","key":"10.1016\/j.bpobgyn.2009.08.002_bib78","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1056\/NEJM200107263450401","article-title":"Parity, oral contraceptives, and the risk of ovarian cancer among carriers and noncarriers of a BRCA1 or BRCA2 mutation","volume":"345","author":"Modan","year":"2001","journal-title":"N Engl J Med"},{"issue":"9017","key":"10.1016\/j.bpobgyn.2009.08.002_bib79","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1016\/S0140-6736(96)90806-5","article-title":"Breast cancer and hormonal contraceptives: collaborative reanalysis of individual data on 53\u2008297 women with breast cancer and 100\u2008239 women without breast cancer from 54 epidemiological studies. Collaborative Group on Hormonal Factors in Breast Cancer","volume":"347","year":"1996","journal-title":"Lancet"},{"issue":"23","key":"10.1016\/j.bpobgyn.2009.08.002_bib80","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1093\/jnci\/94.23.1773","article-title":"Oral contraceptives and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers","volume":"94","author":"Narod","year":"2002","journal-title":"J\u00a0Natl Cancer Inst"},{"issue":"21","key":"10.1016\/j.bpobgyn.2009.08.002_bib81","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1056\/NEJMoa012158","article-title":"Prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations","volume":"346","author":"Rebbeck","year":"2002","journal-title":"N Engl J\u00a0Med"},{"issue":"5645","key":"10.1016\/j.bpobgyn.2009.08.002_bib82","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1126\/science.1088759","article-title":"Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2","volume":"302","author":"King","year":"2003","journal-title":"Science"},{"issue":"17","key":"10.1016\/j.bpobgyn.2009.08.002_bib83","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1093\/jnci\/91.17.1475","article-title":"Breast cancer risk after bilateral prophylactic oophorectomy in BRCA1 mutation carriers","volume":"91","author":"Rebbeck","year":"1999","journal-title":"J Natl Cancer Inst"},{"issue":"3","key":"10.1016\/j.bpobgyn.2009.08.002_bib84","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1001\/jama.288.3.321","article-title":"Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the women's health initiative randomized controlled trial","volume":"288","author":"Rossouw","year":"2002","journal-title":"J Am Med Assoc"},{"issue":"31","key":"10.1016\/j.bpobgyn.2009.08.002_bib85","doi-asserted-by":"crossref","first-page":"7804","DOI":"10.1200\/JCO.2004.00.8151","article-title":"Effect of short-term hormone replacement therapy on breast cancer risk reduction after bilateral prophylactic oophorectomy in BRCA1 and BRCA2 mutation carriers: the PROSE Study Group","volume":"23","author":"Rebbeck","year":"2005","journal-title":"J Clin Oncol"},{"issue":"6","key":"10.1016\/j.bpobgyn.2009.08.002_bib86","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1200\/JCO.2004.06.090","article-title":"Hormone replacement therapy and life expectancy after prophylactic oophorectomy in women with BRCA1\/2 mutations: a decision analysis","volume":"22","author":"Armstrong","year":"2004","journal-title":"J Clin Oncol"},{"issue":"9","key":"10.1016\/j.bpobgyn.2009.08.002_bib87","doi-asserted-by":"crossref","first-page":"2751","DOI":"10.1002\/1097-0142(19930501)71:9<2751::AID-CNCR2820710911>3.0.CO;2-J","article-title":"Primary peritoneal carcinoma after prophylactic oophorectomy in women with a family history of ovarian-cancer - a report of the Gilda-Radner-Familial-Ovarian-Cancer-Registry","volume":"71","author":"Piver","year":"1993","journal-title":"Cancer"},{"issue":"1","key":"10.1016\/j.bpobgyn.2009.08.002_bib88","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3121\/cmr.2007.702","article-title":"Lessons from BRCA: the tubal fimbria emerges as an origin for pelvic serous cancer","volume":"5","author":"Crum","year":"2007","journal-title":"Clin Med Res"},{"issue":"2","key":"10.1016\/j.bpobgyn.2009.08.002_bib89","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1097\/01.pas.0000180854.28831.77","article-title":"The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome","volume":"30","author":"Medeiros","year":"2006","journal-title":"Am J Surg Pathol"},{"issue":"5","key":"10.1016\/j.bpobgyn.2009.08.002_bib90","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1016\/S0029-7844(03)00699-9","article-title":"Unexpected endometrial cancer at prophylactic hysterectomy in a woman with hereditary nonpolyposis colon cancer","volume":"102","author":"Chung","year":"2003","journal-title":"Obstet Gynecol"},{"issue":"18","key":"10.1016\/j.bpobgyn.2009.08.002_bib91","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1093\/jnci\/dji281","article-title":"Risk of ovarian cancer in BRCA1 and BRCA2 mutation negative hereditary breast cancer families","volume":"97","author":"Kauff","year":"2005","journal-title":"J Natl Cancer Inst"},{"issue":"1","key":"10.1016\/j.bpobgyn.2009.08.002_bib92","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1038\/ng853","article-title":"Polygenic susceptibility to breast cancer and implications for prevention","volume":"31","author":"Pharoah","year":"2002","journal-title":"Nat Genet"},{"issue":"2","key":"10.1016\/j.bpobgyn.2009.08.002_bib93","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.bpobgyn.2005.10.017","article-title":"Familial ovarian cancer screening","volume":"20","author":"Rosenthal","year":"2006","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"issue":"6","key":"10.1016\/j.bpobgyn.2009.08.002_bib94","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1002\/cncr.10380","article-title":"The outcome of endometrial carcinoma surveillance by ultrasound scan in women at risk of hereditary nonpolyposis colorectal carcinoma and familial colorectal carcinoma","volume":"94","author":"Dove-Edwin","year":"2002","journal-title":"Cancer"},{"issue":"1","key":"10.1016\/j.bpobgyn.2009.08.002_bib95","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/S0090-8258(03)00371-8","article-title":"Gynecologic screening in hereditary nonpolyposis colorectal cancer","volume":"91","author":"Rijcken","year":"2003","journal-title":"Gynecol Oncol"},{"issue":"4","key":"10.1016\/j.bpobgyn.2009.08.002_bib96","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1002\/ijc.22446","article-title":"Surveillance for endometrial cancer in hereditary nonpolyposis colorectal cancer syndrome","volume":"120","author":"Renkonen-Sinisalo","year":"2007","journal-title":"Int J Cancer"},{"issue":"12","key":"10.1016\/j.bpobgyn.2009.08.002_bib97","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1038\/ncponc1002","article-title":"Prophylactic surgery prevents endometrial and ovarian cancer in Lynch syndrome","volume":"4","author":"Lynch","year":"2007","journal-title":"Nat Clin Pract Oncol"}],"container-title":["Best Practice &amp; Research Clinical Obstetrics &amp; Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521693409001035?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521693409001035?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T08:05:22Z","timestamp":1558598722000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521693409001035"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2]]},"references-count":96,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["S1521693409001035"],"URL":"https:\/\/doi.org\/10.1016\/j.bpobgyn.2009.08.002","relation":{},"ISSN":["1521-6934"],"issn-type":[{"value":"1521-6934","type":"print"}],"subject":[],"published":{"date-parts":[[2010,2]]}}}