{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T23:49:32Z","timestamp":1790120972030,"version":"4.0.1"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Best Practice & Research Clinical Obstetrics & Gynaecology"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.bpobgyn.2017.09.002","type":"journal-article","created":{"date-parts":[[2017,10,4]],"date-time":"2017-10-04T04:49:54Z","timestamp":1507092594000},"page":"74-83","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":70,"special_numbering":"C","title":["High-intensity focused ultrasound therapy"],"prefix":"10.1016","volume":"46","author":[{"given":"Vincent Y.T.","family":"Cheung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bpobgyn.2017.09.002_bib1","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1085\/jgp.26.2.179","article-title":"A\u00a0new method for the generation and use of focused ultrasound in experimental biology","volume":"26","author":"Lynn","year":"1942","journal-title":"Gen Physiol"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib2","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.7863\/ultra.32.8.1353","article-title":"Sonographically guided high-intensity focused ultrasound for the management of uterine fibroids","volume":"32","author":"Cheung","year":"2013","journal-title":"J\u00a0Ultrasound Med"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib3","doi-asserted-by":"crossref","first-page":"95","DOI":"10.14366\/usg.16040","article-title":"Current status of high-intensity focused ultrasound for the management of uterine adenomyosis","volume":"36","author":"Cheung","year":"2017","journal-title":"Ultrasonography"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib4","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1055\/s-0030-1251481","article-title":"Magnetic resonance-guided focused ultrasound surgery","volume":"28","author":"Al Hilli","year":"2010","journal-title":"Semin Reprod Med"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib5","first-page":"161","article-title":"Treatment of symptomatic uterine leiomyomata with high intensity focused ultrasound: a preliminary clinical study","volume":"11","author":"Wang","year":"2002","journal-title":"Chin J Ultrasonogr"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib6","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1111\/aogs.13159","article-title":"High intensity focused ultrasound for the treatment of adenomyosis: selection criteria, efficacy, safety and fertility","volume":"96","author":"Zhang","year":"2017","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib7","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1097\/SLA.0b013e3182128a8b","article-title":"High-intensity focused ultrasound for hepatocellular carcinoma: a single-center experience","volume":"253","author":"Ng","year":"2011","journal-title":"Ann Surg"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib8","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.jmig.2017.01.010","article-title":"Pilot study of the Mirabilis system prototype for rapid noninvasive uterine myoma treatment using an ultrasound-guided volumetric shell ablation technique","volume":"24","author":"Parsons","year":"2017","journal-title":"J\u00a0Minim Invasive Gynecol"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib9","unstructured":"U.S. Food and drug administration; https\/\/www.accessdata.fda.gov\/scripts\/cdrh\/cfdocs\/cfPMA\/pma.cfm?id=P040003S006. [accessed 29 July 2017]."},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib10","first-page":"290","article-title":"The UFS-QOL, a new disease-specific symptom and health-related quality of life questionnaire for leiomyomata","volume":"99","author":"Spies","year":"2002","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib11","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/S0140-6736(95)91689-X","article-title":"Microwaves for menorrhagia: a new fast technique for endometrial ablation","volume":"346","author":"Sharp","year":"1995","journal-title":"Lancet"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib12","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1097\/01.AOG.0000275283.39475.f6","article-title":"Sustained relief of leiomyoma symptoms by using focused ultrasound surgery","volume":"110","author":"Stewart","year":"2007","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib13","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.jvir.2011.01.458","article-title":"Magnetic resonance-guided focused ultrasound of uterine leiomyomas: review of a 12-month outcome of 130 clinical patients","volume":"22","author":"Gorny","year":"2011","journal-title":"J\u00a0Vasc Interv Radiol"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib14","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.2214\/ajr.183.6.01831713","article-title":"MRI guidance of focused ultrasound therapy of uterine fibroids: early results","volume":"183","author":"Hindley","year":"2004","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib15","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1002\/uog.4099","article-title":"Clinical improvement and shrinkage of uterine fibroids after thermal ablation by magnetic resonance-guided focused ultrasound surgery","volume":"30","author":"Rabinovici","year":"2007","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib16","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.fertnstert.2005.04.072","article-title":"Clinical outcomes of focused ultrasound surgery for the treatment of uterine fibroids","volume":"85","author":"Stewart","year":"2006","journal-title":"Fertil Steril"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib17","first-page":"1","article-title":"Magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) treatment of symptomatic uterine fibroids: an evidence-based analysis","volume":"15","author":"Pron","year":"2015","journal-title":"Ont Health Technol Assess Ser"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib18","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.fertnstert.2015.11.014","article-title":"PROMISe trial: a pilot, randomized, placebo-controlled trial of magnetic resonance guided focused ultrasound for uterine fibroids","volume":"105","author":"Jacoby","year":"2016","journal-title":"Fertil Steril"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib19","doi-asserted-by":"crossref","first-page":"280","DOI":"10.3109\/02656736.2014.996790","article-title":"Ultrasound-guided high intensity focused ultrasound for the treatment of gynaecological diseases: a review of safety and efficacy","volume":"31","author":"Zhang","year":"2015","journal-title":"Int J Hyperth"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib20","doi-asserted-by":"crossref","first-page":"3624","DOI":"10.1016\/j.ejrad.2011.05.036","article-title":"Feasibility of MRI-guided high intensity focused ultrasound treatment for adenomyosis","volume":"81","author":"Fan","year":"2012","journal-title":"Eur J Radiol"},{"issue":"9 Pt 1","key":"10.1016\/j.bpobgyn.2017.09.002_bib21","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/S1051-0443(07)61769-2","article-title":"Quality improvement guidelines for the reporting and archiving of interventional radiology procedures","volume":"13","author":"Omary","year":"2002","journal-title":"J\u00a0Vasc Interv Radiol"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib22","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.fertnstert.2009.02.083","article-title":"What factors currently limit magnetic resonance-guided focused ultrasound of leiomyomas? a survey conducted at the first international symposium devoted to clinical magnetic resonance-guided focused ultrasound","volume":"94","author":"Taran","year":"2010","journal-title":"Fertil Steril"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib23","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/j.ultsonch.2015.05.031","article-title":"Safety of ultrasound-guided ultrasound ablation for uterine fibroids and adenomyosis: a review of 9988 cases","volume":"27","author":"Chen","year":"2015","journal-title":"Ultrason Sonochem"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib24","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1177\/1933719113497289","article-title":"Magnetic resonance-guided focused ultrasound myomectomy: safety, efficacy, subsequent fertility and quality-of-life improvements, a systematic review","volume":"21","author":"Gizzo","year":"2014","journal-title":"Reprod Sci"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib25","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1097\/RLI.0b013e3182806904","article-title":"Magnetic resonance imaging-guided focused ultrasound treatment of symptomatic uterine fibroids: impact of technology advancement on ablation volumes in 115 patients","volume":"48","author":"Trumm","year":"2013","journal-title":"Invest Radiol"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib26","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.ultsonch.2015.05.033","article-title":"Ultrasound-guided high-intensity focused ultrasound treatment for uterine fibroid & adenomyosis: a single center experience from the Republic of Korea","volume":"27","author":"Lee","year":"2015","journal-title":"Ultrason Sonochem"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib27","article-title":"Evaluation of high-intensity focused ultrasound ablation for uterine fibroids: an IDEAL prospective exploration study","author":"Chen","year":"2017","journal-title":"BJOG"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib28","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1111\/j.1471-0528.2005.00696.x","article-title":"The association of hysterectomy and menopause: a prospective cohort study","volume":"112","author":"Farquhar","year":"2005","journal-title":"BJOG"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib29","doi-asserted-by":"crossref","first-page":"1996","DOI":"10.1093\/humrep\/dem105","article-title":"Loss of ovarian reserve after uterine artery embolization: a randomized comparison with hysterectomy","volume":"22","author":"Hehenkamp","year":"2007","journal-title":"Hum Reprod"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib30","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0015-0282(02)03164-3","article-title":"Ovarian reserve after uterine artery embolization for leiomyomata","volume":"78","author":"Tulandi","year":"2002","journal-title":"Fertil Steril"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib31","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.jogc.2016.02.006","article-title":"Ovarian reserve after ultrasound-guided high-intensity focused ultrasound for uterine fibroids: preliminary experience","volume":"38","author":"Cheung","year":"2016","journal-title":"J\u00a0Obstet Gynaecol Can"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib32","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1002\/uog.7435","article-title":"Magnetic resonance-guided focused ultrasound (MRgFUS) compared with abdominal hysterectomy for treatment of uterine leiomyomas","volume":"34","author":"Taran","year":"2009","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib33","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1007\/s00270-013-0582-6","article-title":"Midterm results after uterine artery embolization versus MR-guided high-intensity focused ultrasound treatment for symptomatic uterine fibroids","volume":"36","author":"Froeling","year":"2013","journal-title":"Cardiovasc Interv Radiol"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib34","doi-asserted-by":"crossref","first-page":"2265","DOI":"10.1016\/j.ejrad.2013.08.045","article-title":"Outcome of uterine artery embolization versus MR-guided high-intensity focused ultrasound treatment for uterine fibroids: long-term results","volume":"82","author":"Froeling","year":"2013","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib35","doi-asserted-by":"crossref","first-page":"2649","DOI":"10.1007\/s00330-014-3295-6","article-title":"Volumetric MR-guided high-intensity focused ultrasound versus uterine artery embolisation for treatment of symptomatic uterine fibroids: comparison of symptom improvement and reintervention rates","volume":"24","author":"Ikink","year":"2014","journal-title":"Eur Radiol"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib36","doi-asserted-by":"crossref","first-page":"500.e1","DOI":"10.1016\/j.ajog.2016.12.177","article-title":"Periprocedural outcomes comparing fibroid embolization and focused ultrasound: a randomized controlled trial and comprehensive cohort analysis","volume":"216","author":"Barnard","year":"2017","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib37","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3109\/02656736.2013.775672","article-title":"The effect of high-intensity focused ultrasound treatment on immune function in patients with uterine fibroids","volume":"29","author":"Wang","year":"2013","journal-title":"Int J Hyperth"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib38","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1007\/s00404-013-2775-2","article-title":"Effect of high-intensity focused ultrasound on sexual function in the treatment of uterine fibroids: comparison to conventional myomectomy","volume":"288","author":"Wang","year":"2013","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib39","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.jmig.2013.09.004","article-title":"Ultrasound-guided high-intensity focused ultrasound vs laparoscopic myomectomy for symptomatic uterine myomas","volume":"21","author":"Wang","year":"2014","journal-title":"J\u00a0Minim Invasive Gynecol"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib40","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1007\/s00270-010-9909-8","article-title":"A\u00a0comparative study of fibroid ablation rates using radio frequency or high-intensity focused ultrasound","volume":"33","author":"Meng","year":"2010","journal-title":"Cardiovasc Interv Radiol"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib41","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1016\/j.fertnstert.2011.06.062","article-title":"Comparing focused ultrasound and uterine artery embolization for uterine fibroids-rationale and design of the Fibroid Interventions: reducing symptoms today and tomorrow (FIRSTT) trial","volume":"96","author":"Bouwsma","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib42","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.fertnstert.2008.10.001","article-title":"Pregnancy outcome after magnetic resonance-guided focused ultrasound surgery (MRgFUS) for conservative treatment of uterine fibroids","volume":"93","author":"Rabinovici","year":"2010","journal-title":"Fertil Steril"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib43","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1097\/GCO.0000000000000070","article-title":"Reproductive impact of MRI-guided focused ultrasound surgery for fibroids: a systematic review of the evidence","volume":"26","author":"Clark","year":"2014","journal-title":"Curr Opin Obstet Gynecol"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib44","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.ijgo.2012.01.011","article-title":"Outcome of unintended pregnancy after ultrasound-guided high-intensity focused ultrasound ablation of uterine fibroids","volume":"117","author":"Qin","year":"2012","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib45","first-page":"845","article-title":"Pregnancy outcomes and symptom improvement of patients with adenomyosis treated with high intensity focused ultrasound ablation","volume":"51","author":"Zhou","year":"2016","journal-title":"Zhonghua Fu Chan Ke Za Zhi"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib46","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1111\/j.1447-0756.2010.01344.x","article-title":"Successful in\u00a0vitro fertilization pregnancy following magnetic resonance-guided focused ultrasound surgery for uterine fibroids","volume":"37","author":"Zaher","year":"2011","journal-title":"J\u00a0Obstet Gynaecol Res"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib47","doi-asserted-by":"crossref","first-page":"e9","DOI":"10.1016\/j.fertnstert.2011.04.056","article-title":"Magnetic resonance-guided focused ultrasound surgery for leiomyoma-associated infertility","volume":"96","author":"Bouwsma","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.bpobgyn.2017.09.002_bib48","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1093\/humrep\/dei458","article-title":"Pregnancy and live birth after focused ultrasound surgery for symptomatic focal adenomyosis: a case report","volume":"21","author":"Ricabinovi","year":"2006","journal-title":"Hum Reprod"}],"container-title":["Best Practice & Research Clinical Obstetrics & Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521693417301359?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521693417301359?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,27]],"date-time":"2018-08-27T00:34:57Z","timestamp":1535330097000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521693417301359"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":48,"alternative-id":["S1521693417301359"],"URL":"https:\/\/doi.org\/10.1016\/j.bpobgyn.2017.09.002","relation":{},"ISSN":["1521-6934"],"issn-type":[{"value":"1521-6934","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High-intensity focused ultrasound therapy","name":"articletitle","label":"Article Title"},{"value":"Best Practice & Research Clinical Obstetrics & Gynaecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bpobgyn.2017.09.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}