{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T00:09:15Z","timestamp":1778890155685,"version":"3.51.4"},"reference-count":96,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100007206","name":"Vanderbilt Institute for Clinical and Translational Research","doi-asserted-by":"publisher","award":["1- UL-1-TR000445"],"award-info":[{"award-number":["1- UL-1-TR000445"]}],"id":[{"id":"10.13039\/100007206","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000097","name":"National Center for Research Resources","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01-MH70560"],"award-info":[{"award-number":["R01-MH70560"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biological Psychiatry: Cognitive Neuroscience and Neuroimaging"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1016\/j.bpsc.2019.06.007","type":"journal-article","created":{"date-parts":[[2019,6,26]],"date-time":"2019-06-26T23:46:22Z","timestamp":1561592782000},"page":"1004-1012","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Disrupted Habituation in the Early Stage of Psychosis"],"prefix":"10.1016","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5320-4619","authenticated-orcid":false,"given":"Suzanne N.","family":"Avery","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maureen","family":"McHugo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristan","family":"Armstrong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer U.","family":"Blackford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil D.","family":"Woodward","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3601-9910","authenticated-orcid":false,"given":"Stephan","family":"Heckers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bpsc.2019.06.007_bib1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1037\/h0022681","article-title":"Habituation: A model phenomenon for the study of neuronal substrates of behavior","volume":"73","author":"Thompson","year":"1966","journal-title":"Psychol Rev"},{"key":"10.1016\/j.bpsc.2019.06.007_bib2","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.nlm.2008.09.012","article-title":"Habituation revisited: An updated and revised description of the behavioral characteristics of habituation","volume":"92","author":"Rankin","year":"2009","journal-title":"Neurobiol Learn Mem"},{"key":"10.1016\/j.bpsc.2019.06.007_bib3","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1037\/h0029810","article-title":"Habituation: A dual-process theory","volume":"77","author":"Groves","year":"1970","journal-title":"Psychol Rev"},{"key":"10.1016\/j.bpsc.2019.06.007_bib4","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1126\/science.167.3926.1740","article-title":"Habituation and dishabituation of the gill-withdrawal reflex in Aplysia","volume":"167","author":"Pinsker","year":"1970","journal-title":"Science"},{"key":"10.1016\/j.bpsc.2019.06.007_bib5","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/j.neuron.2006.01.030","article-title":"Linking implicit and explicit memory: Common encoding factors and shared representations","volume":"49","author":"Turk-Browne","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.bpsc.2019.06.007_bib6","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1016\/j.neuropsychologia.2003.11.015","article-title":"Hippocampal adaptation to face repetition in healthy elderly and mild cognitive impairment","volume":"42","author":"Johnson","year":"2004","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.bpsc.2019.06.007_bib7","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0896-6273(00)80448-1","article-title":"Priming and the brain","volume":"20","author":"Schacter","year":"1998","journal-title":"Neuron"},{"key":"10.1016\/j.bpsc.2019.06.007_bib8","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0959-4388(98)80144-X","article-title":"Properties and mechanisms of perceptual priming","volume":"8","author":"Wiggs","year":"1998","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.bpsc.2019.06.007_bib9","first-page":"16","article-title":"Babies and brains: Habituation in infant cognition and functional neuroimaging","volume":"2","author":"Turk-Browne","year":"2008","journal-title":"Front Hum Neurosci"},{"key":"10.1016\/j.bpsc.2019.06.007_bib10","doi-asserted-by":"crossref","first-page":"57","DOI":"10.2307\/1131437","article-title":"A\u00a0meta-analysis of infant habituation and recognition memory performance as predictors of later IQ","volume":"64","author":"McCall","year":"1993","journal-title":"Child Dev"},{"key":"10.1016\/j.bpsc.2019.06.007_bib11","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.neubiorev.2017.05.028","article-title":"Habituation is altered in neuropsychiatric disorders\u2014a comprehensive review with recommendations for experimental design and analysis","volume":"80","author":"McDiarmid","year":"2017","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.bpsc.2019.06.007_bib12","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1002\/bs.3830080402","article-title":"Psychological deficit in schizophrenia","volume":"8","author":"Shakow","year":"1963","journal-title":"Behav Sci"},{"key":"10.1016\/j.bpsc.2019.06.007_bib13","series-title":"The Madness Within Us","author":"Freedman","year":"2010"},{"key":"10.1016\/j.bpsc.2019.06.007_bib14","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1001\/archpsyc.1996.01830120052009","article-title":"Inhibitory gating of an evoked response to repeated auditory stimuli in schizophrenic and normal subjects. Human recordings, computer simulation, and an animal model","volume":"53","author":"Freedman","year":"1996","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib15","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/0006-3223(94)91176-2","article-title":"Sensorimotor gating and habituation evoked by electro-cutaneous stimulation in schizophrenia","volume":"36","author":"Bolino","year":"1994","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib16","first-page":"131","article-title":"Gating and habituation deficits in the schizophrenia disorders","volume":"3","author":"Braff","year":"1995","journal-title":"Clin Neurosci"},{"key":"10.1016\/j.bpsc.2019.06.007_bib17","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1192\/bjp.134.1.39","article-title":"The sensory filter in schizophrenia: A study of habituation, arousal, and the dopamine hypothesis","volume":"134","author":"Horvath","year":"1979","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1469-8986.1982.tb02589.x","article-title":"Habituation of the blink reflex in normals and schizophrenic patients","volume":"19","author":"Geyer","year":"1982","journal-title":"Psychophysiology"},{"key":"10.1016\/j.bpsc.2019.06.007_bib19","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/0304-3940(92)90002-O","article-title":"Startle reflex habituation in functional psychoses: A controlled study","volume":"145","author":"Bolino","year":"1992","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.bpsc.2019.06.007_bib20","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.schres.2010.03.004","article-title":"Inhibition of the P50 cerebral evoked response to repeated auditory stimuli: Results from the Consortium on Genetics of Schizophrenia","volume":"119","author":"Olincy","year":"2010","journal-title":"Schizophr Res"},{"key":"10.1016\/j.bpsc.2019.06.007_bib21","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1038\/s41380-018-0231-1","article-title":"Memory and cognition in schizophrenia","volume":"24","author":"Guo","year":"2019","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib22","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1037\/a0014708","article-title":"Neurocognition in first-episode schizophrenia: A meta-analytic review","volume":"23","author":"Mesholam-Gately","year":"2009","journal-title":"Neuropsychology"},{"key":"10.1016\/j.bpsc.2019.06.007_bib23","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1001\/archpsyc.1991.01810310036007","article-title":"Neuropsychological function in schizophrenia. Selective impairment in memory and learning","volume":"48","author":"Saykin","year":"1991","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib24","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1016\/j.biopsych.2005.01.033","article-title":"Sustained activation of the hippocampus in response to fearful faces in schizophrenia","volume":"57","author":"Holt","year":"2005","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib25","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.schres.2013.10.017","article-title":"Reduced habituation in patients with schizophrenia","volume":"151","author":"Williams","year":"2013","journal-title":"Schizophr Res"},{"key":"10.1016\/j.bpsc.2019.06.007_bib26","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1001\/archgenpsychiatry.2011.1592","article-title":"Cognitive functioning in prodromal psychosis: A meta-analysis","volume":"69","author":"Fusar-Poli","year":"2012","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib27","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1093\/schbul\/sbm018","article-title":"Cognitive functioning in the schizophrenia prodrome","volume":"33","author":"Simon","year":"2007","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.bpsc.2019.06.007_bib28","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.schres.2018.06.049","article-title":"Impaired associative inference in the early stage of psychosis","volume":"202","author":"Armstrong","year":"2018","journal-title":"Schizophr Res"},{"key":"10.1016\/j.bpsc.2019.06.007_bib29","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.schres.2019.07.060","article-title":"Impaired relational memory in the early stage of psychosis","volume":"212","author":"Avery","year":"2019","journal-title":"Schizophr Res"},{"key":"10.1016\/j.bpsc.2019.06.007_bib30","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.biopsych.2011.09.016","article-title":"Intact relational memory and normal hippocampal structure in the early stage of psychosis","volume":"71","author":"Williams","year":"2012","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib31","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1001\/archpsyc.63.4.356","article-title":"The neural basis of relational memory deficits in schizophrenia","volume":"63","author":"Ong\u00fcr","year":"2006","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib32","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1176\/ajp.153.3.321","article-title":"What are the functional consequences of neurocognitive deficits in schizophrenia?","volume":"153","author":"Green","year":"1996","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib33","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.schres.2004.09.009","article-title":"Longitudinal studies of cognition and functional outcome in schizophrenia: Implications for MATRICS","volume":"72","author":"Green","year":"2004","journal-title":"Schizophr Res"},{"key":"10.1016\/j.bpsc.2019.06.007_bib34","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1177\/070674371405900103","article-title":"Neurocognition: Clinical and functional outcomes in schizophrenia","volume":"59","author":"Lepage","year":"2014","journal-title":"Can J Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib35","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1001\/jamapsychiatry.2015.0276","article-title":"Functional and neuroanatomic specificity of episodic memory dysfunction in schizophrenia: A functional magnetic resonance imaging study of the relational and item-specific encoding task","volume":"72","author":"Ragland","year":"2015","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib36","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1002\/hipo.10189","article-title":"Hippocampal activation during transitive inference in humans","volume":"14","author":"Heckers","year":"2004","journal-title":"Hippocampus"},{"key":"10.1016\/j.bpsc.2019.06.007_bib37","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.pscychresns.2008.09.008","article-title":"The role of the hippocampus in transitive inference","volume":"172","author":"Zalesak","year":"2009","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.bpsc.2019.06.007_bib38","doi-asserted-by":"crossref","first-page":"206","DOI":"10.3109\/00048674.2010.547456","article-title":"Relational memory in first episode psychosis: Implications for progressive hippocampal dysfunction after illness onset","volume":"45","author":"Bartholomeusz","year":"2011","journal-title":"Aust N Z J Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib39","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/s41537-018-0063-7","article-title":"Diverse definitions of the early course of schizophrenia\u2014a targeted literature review","volume":"4","author":"Newton","year":"2018","journal-title":"NPJ Schizophr"},{"key":"10.1016\/j.bpsc.2019.06.007_bib40","series-title":"Structured Clinical Interview for the DSM-IV-TR Axis I Disorders, Research Version, Patient Edition (SCID-I\/P)","author":"First","year":"2002"},{"key":"10.1016\/j.bpsc.2019.06.007_bib41","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1038\/nn.2163","article-title":"Neural repetition suppression reflects fulfilled perceptual expectations","volume":"11","author":"Summerfield","year":"2008","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.bpsc.2019.06.007_bib42","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.biopsych.2010.05.035","article-title":"Eye-movement behavior reveals relational memory impairment in schizophrenia","volume":"68","author":"Williams","year":"2010","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib43","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1111\/j.1399-5618.2012.01036.x","article-title":"Relational memory in psychotic bipolar disorder","volume":"14","author":"Sheffield","year":"2012","journal-title":"Bipolar Disord"},{"key":"10.1016\/j.bpsc.2019.06.007_bib44","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/j.neuron.2009.08.025","article-title":"The eyes have it: Hippocampal activity predicts expression of memory in eye movements","volume":"63","author":"Hannula","year":"2009","journal-title":"Neuron"},{"key":"10.1016\/j.bpsc.2019.06.007_bib45","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0022-3999(63)90004-7","article-title":"Habituation of the psycho-galvanic reflex during serial tests","volume":"52","author":"Montagu","year":"1963","journal-title":"J\u00a0Psychosom Res"},{"key":"10.1016\/j.bpsc.2019.06.007_bib46","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1093\/scan\/nsw095","article-title":"Slow to warm up: The role of habituation in social fear","volume":"11","author":"Avery","year":"2016","journal-title":"Soc Cogn Affect Neurosci"},{"key":"10.1016\/j.bpsc.2019.06.007_bib47","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1176\/appi.ajp.2012.12010056","article-title":"Thalamocortical dysconnectivity in schizophrenia","volume":"169","author":"Woodward","year":"2012","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib48","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/hbm.460020402","article-title":"Statistical parametric maps in functional imaging: A general linear approach","volume":"2","author":"Friston","year":"1995","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.bpsc.2019.06.007_bib49","first-page":"85","article-title":"Characterizing spatially varying performance to improve multi-atlas multi-label segmentation","volume":"22","author":"Asman","year":"2011","journal-title":"Inf Process Med Imaging"},{"key":"10.1016\/j.bpsc.2019.06.007_bib50","first-page":"90341E","article-title":"Statistical label fusion with hierarchical performance models","volume":"9034","author":"Asman","year":"2014","journal-title":"Proc SPIE Int Soc Opt Eng"},{"key":"10.1016\/j.bpsc.2019.06.007_bib51","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.tics.2013.03.005","article-title":"Long-axis specialization of the human hippocampus","volume":"17","author":"Poppenk","year":"2013","journal-title":"Trends Cogn Sci"},{"key":"10.1016\/j.bpsc.2019.06.007_bib52","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1038\/nrn3785","article-title":"Functional organization of the hippocampal longitudinal axis","volume":"15","author":"Strange","year":"2014","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.bpsc.2019.06.007_bib53","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/s11065-009-9114-1","article-title":"Neurobiological markers of illness onset in psychosis and schizophrenia: The search for a moving target","volume":"19","author":"Pantelis","year":"2009","journal-title":"Neuropsychol Rev"},{"key":"10.1016\/j.bpsc.2019.06.007_bib54","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1016\/j.neubiorev.2012.07.012","article-title":"Multimodal meta-analysis of structural and functional brain changes in first episode psychosis and the effects of antipsychotic medication","volume":"36","author":"Radua","year":"2012","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.bpsc.2019.06.007_bib55","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.schres.2016.08.020","article-title":"Dopamine, fronto-striato-thalamic circuits and risk for psychosis","volume":"180","author":"Dandash","year":"2017","journal-title":"Schizophr Res"},{"key":"10.1016\/j.bpsc.2019.06.007_bib56","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1162\/jocn.2009.21229","article-title":"A\u00a0multimodal neural network recruited by expertise with musical notation","volume":"22","author":"Wong","year":"2010","journal-title":"J\u00a0Cogn Neurosci"},{"key":"10.1016\/j.bpsc.2019.06.007_bib57","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.tics.2005.11.006","article-title":"Repetition and the brain: Neural models of stimulus-specific effects","volume":"10","author":"Grill-Spector","year":"2006","journal-title":"Trends Cogn Sci"},{"key":"10.1016\/j.bpsc.2019.06.007_bib58","article-title":"Region of interest analysis using an SPM toolbox [abstract] Presented at the 8th International Conference on Functional Mapping of the Human Brain, June 2\u20136, 2002, Sendai, Japan","volume":"16","author":"Brett","year":"2002","journal-title":"Neuroimage"},{"key":"10.1016\/j.bpsc.2019.06.007_bib59","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.neuroimage.2014.09.059","article-title":"Amygdala habituation: A reliable fMRI phenotype","volume":"103","author":"Plichta","year":"2014","journal-title":"Neuroimage"},{"key":"10.1016\/j.bpsc.2019.06.007_bib60","author":"Preacher"},{"key":"10.1016\/j.bpsc.2019.06.007_bib61","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.eurpsy.2017.06.006","article-title":"Volumetric and morphological characteristics of the hippocampus are associated with progression to schizophrenia in patients with first-episode psychosis","volume":"45","author":"Sauras","year":"2017","journal-title":"Eur Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib62","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1038\/npp.2017.5","article-title":"Progressive decline in hippocampal CA1 volume in individuals at ultra-high-risk for psychosis who do not remit: findings from the Longitudinal Youth at Risk Study","volume":"42","author":"Ho","year":"2017","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bpsc.2019.06.007_bib63","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1007\/s007020200073","article-title":"Hippocampal neurons in schizophrenia","volume":"109","author":"Heckers","year":"2002","journal-title":"J\u00a0Neural Transm"},{"key":"10.1016\/j.bpsc.2019.06.007_bib64","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1101\/lm.029728.112","article-title":"Hippocampal networks habituate as novelty accumulates","volume":"20","author":"Murty","year":"2013","journal-title":"Learn Mem"},{"key":"10.1016\/j.bpsc.2019.06.007_bib65","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1093\/cercor\/bhm104","article-title":"Activating the medial temporal lobe during oddity judgment for faces and scenes","volume":"18","author":"Lee","year":"2008","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.bpsc.2019.06.007_bib66","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1152\/jn.91323.2008","article-title":"Responses of human medial temporal lobe neurons are modulated by stimulus repetition","volume":"103","author":"Pedreira","year":"2010","journal-title":"J\u00a0Neurophysiol"},{"key":"10.1016\/j.bpsc.2019.06.007_bib67","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1176\/appi.ajp.2012.12040490","article-title":"Social and nonsocial cognition in bipolar disorder and schizophrenia: Relative levels of impairment","volume":"170","author":"Lee","year":"2013","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib68","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1038\/nrn4005","article-title":"Social cognition in schizophrenia","volume":"16","author":"Green","year":"2015","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.bpsc.2019.06.007_bib69","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1162\/jocn.2007.19.10.1690","article-title":"Rapid onset relational memory effects are evident in eye movement behavior, but not in hippocampal amnesia","volume":"19","author":"Hannula","year":"2007","journal-title":"J\u00a0Cogn Neurosci"},{"key":"10.1016\/j.bpsc.2019.06.007_bib70","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.neuron.2013.02.011","article-title":"Imaging patients with psychosis and a mouse model establishes a spreading pattern of hippocampal dysfunction and implicates glutamate as a driver","volume":"78","author":"Schobel","year":"2013","journal-title":"Neuron"},{"key":"10.1016\/j.bpsc.2019.06.007_bib71","doi-asserted-by":"crossref","first-page":"103","DOI":"10.3389\/fnint.2013.00103","article-title":"Longterm-habituation of the startle response in mice is stimulus modality, but not context specific","volume":"7","author":"Pilz","year":"2014","journal-title":"Front Integr Neurosci"},{"key":"10.1016\/j.bpsc.2019.06.007_bib72","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.nlm.2008.07.011","article-title":"Habituation: A history","volume":"92","author":"Thompson","year":"2009","journal-title":"Neurobiol Learn Mem"},{"key":"10.1016\/j.bpsc.2019.06.007_bib73","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1152\/jn.90479.2008","article-title":"Neurobiology of a simple memory","volume":"100","author":"Wilson","year":"2008","journal-title":"J\u00a0Neurophysiol"},{"key":"10.1016\/j.bpsc.2019.06.007_bib74","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.nlm.2008.08.004","article-title":"Behavioral and genetic characterization of habituation using Caenorhabditis elegans","volume":"92","author":"Giles","year":"2009","journal-title":"Neurobiol Learn Mem"},{"key":"10.1016\/j.bpsc.2019.06.007_bib75","doi-asserted-by":"crossref","first-page":"419","DOI":"10.3389\/fnint.2014.00097","article-title":"Habituation mechanisms and their importance for cognitive function","volume":"8","author":"Schmid","year":"2015","journal-title":"Front Integr Neurosci"},{"key":"10.1016\/j.bpsc.2019.06.007_bib76","doi-asserted-by":"crossref","first-page":"14711","DOI":"10.1073\/pnas.1111230108","article-title":"Olfactory habituation: Fresh insights from flies","volume":"108","author":"Glanzman","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.bpsc.2019.06.007_bib77","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.nlm.2009.03.005","article-title":"Habituation in Aplysia: The Cheshire Cat of neurobiology","volume":"92","author":"Glanzman","year":"2009","journal-title":"Neurobiol Learn Mem"},{"key":"10.1016\/j.bpsc.2019.06.007_bib78","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1016\/j.neuron.2014.04.035","article-title":"Network plasticity in adaptive filtering and behavioral habituation","volume":"82","author":"Ramaswami","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.bpsc.2019.06.007_bib79","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1146\/annurev.ph.25.030163.002553","article-title":"Higher nervous functions; the orienting reflex","volume":"25","author":"Sokolov","year":"1963","journal-title":"Annu Rev Physiol"},{"key":"10.1016\/j.bpsc.2019.06.007_bib80","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/S0896-6273(00)80315-3","article-title":"Single neuron activity in human hippocampus and amygdala during recognition of faces and objects","volume":"18","author":"Fried","year":"1997","journal-title":"Neuron"},{"key":"10.1016\/j.bpsc.2019.06.007_bib81","doi-asserted-by":"crossref","first-page":"8378","DOI":"10.1073\/pnas.072194099","article-title":"Single-neuron correlates of subjective vision in the human medial temporal lobe","volume":"99","author":"Kreiman","year":"2002","journal-title":"Proc Natl Acad Sci U\u00a0S A"},{"key":"10.1016\/j.bpsc.2019.06.007_bib82","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1038\/78868","article-title":"Category-specific visual responses of single neurons in the human medial temporal lobe","volume":"3","author":"Kreiman","year":"2000","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.bpsc.2019.06.007_bib83","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0896-6273(00)00019-2","article-title":"Effects of visual experience on the representation of objects in the prefrontal cortex","volume":"27","author":"Rainer","year":"2000","journal-title":"Neuron"},{"key":"10.1016\/j.bpsc.2019.06.007_bib84","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/BF00229353","article-title":"The effects of stimulus novelty and familiarity on neuronal activity in the amygdala of monkeys performing recognition memory tasks","volume":"93","author":"Wilson","year":"1993","journal-title":"Exp Brain Res"},{"key":"10.1016\/j.bpsc.2019.06.007_bib85","doi-asserted-by":"crossref","first-page":"9222","DOI":"10.1523\/JNEUROSCI.1076-17.2017","article-title":"Dedicated hippocampal inhibitory networks for locomotion and immobility","volume":"37","author":"Arriaga","year":"2017","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.bpsc.2019.06.007_bib86","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.schres.2014.09.041","article-title":"GABAergic mechanisms of hippocampal hyperactivity in schizophrenia","volume":"167","author":"Heckers","year":"2015","journal-title":"Schizophr Res"},{"key":"10.1016\/j.bpsc.2019.06.007_bib87","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1001\/archpsyc.57.7.637","article-title":"Schizophrenia as a disorder of developmentally reduced synaptic connectivity","volume":"57","author":"McGlashan","year":"2000","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib88","first-page":"423","article-title":"Hippocampal network modularity is associated with relational memory dysfunction in schizophrenia","volume":"3","author":"Avery","year":"2018","journal-title":"Biol Psychiatry Cogn Neurosci Neuroimaging"},{"key":"10.1016\/j.bpsc.2019.06.007_bib89","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1093\/schbul\/sbm071","article-title":"Inefficient face detection in schizophrenia","volume":"34","author":"Chen","year":"2008","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.bpsc.2019.06.007_bib90","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1038\/mp.2014.91","article-title":"What causes aberrant salience in schizophrenia? A role for impaired short-term habituation and the GRIA1 (GluA1) AMPA receptor subunit","volume":"19","author":"Barkus","year":"2014","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib91","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1176\/appi.ajp.160.1.13","article-title":"Psychosis as a state of aberrant salience: A framework linking biology, phenomenology, and pharmacology in schizophrenia","volume":"160","author":"Kapur","year":"2003","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.bpsc.2019.06.007_bib92","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0166-4328(89)80123-8","article-title":"Adrenocorticoid receptor binding in the rat hippocampus: Strain-dependent covariations with arousal and habituation to novelty","volume":"33","author":"Patacchioli","year":"1989","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.bpsc.2019.06.007_bib93","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.neubiorev.2006.03.006","article-title":"Habituation in rodents: A review of behavior, neurobiology, and genetics","volume":"30","author":"Leussis","year":"2006","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.bpsc.2019.06.007_bib94","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1152\/jn.00679.2016","article-title":"Neural circuits: A circuit for saccadic suppression in the primate brain","volume":"117","author":"Berman","year":"2017","journal-title":"J\u00a0Neurophysiol"},{"key":"10.1016\/j.bpsc.2019.06.007_bib95","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/j.conb.2013.02.001","article-title":"Role of the basal ganglia in the control of sleep and wakefulness","volume":"23","author":"Lazarus","year":"2013","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.bpsc.2019.06.007_bib96","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1176\/ajp.156.9.1358","article-title":"Memory impairment in schizophrenia: A meta-analysis","volume":"156","author":"Aleman","year":"1999","journal-title":"Am J Psychiatry"}],"container-title":["Biological Psychiatry: Cognitive Neuroscience and Neuroimaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451902219301727?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451902219301727?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T23:31:58Z","timestamp":1778887918000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2451902219301727"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":96,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["S2451902219301727"],"URL":"https:\/\/doi.org\/10.1016\/j.bpsc.2019.06.007","relation":{},"ISSN":["2451-9022"],"issn-type":[{"value":"2451-9022","type":"print"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Disrupted Habituation in the Early Stage of Psychosis","name":"articletitle","label":"Article Title"},{"value":"Biological Psychiatry: Cognitive Neuroscience and Neuroimaging","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bpsc.2019.06.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}