{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T13:22:27Z","timestamp":1762521747172,"version":"build-2065373602"},"reference-count":60,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Dundee University Medical School","award":["AT27"],"award-info":[{"award-number":["AT27"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biological Psychiatry: Cognitive Neuroscience and Neuroimaging"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.bpsc.2020.09.010","type":"journal-article","created":{"date-parts":[[2020,9,16]],"date-time":"2020-09-16T12:14:12Z","timestamp":1600258452000},"page":"126-134","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Alcohol Binge Drinking: Negative and Positive Valence System Abnormalities"],"prefix":"10.1016","volume":"6","author":[{"given":"Serenella","family":"Tolomeo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1688-1653","authenticated-orcid":false,"given":"Jennifer A.","family":"Macfarlane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex","family":"Baldacchino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George F.","family":"Koob","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9822-8753","authenticated-orcid":false,"given":"J. Douglas","family":"Steele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bpsc.2020.09.010_bib2","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/S2215-0366(18)30337-7","article-title":"The global burden of disease attributable to alcohol and drug use in 195 countries and territories, 1990\u20132016: A systematic analysis for the Global Burden of Disease Study 2016","volume":"5","author":"Degenhardt","year":"2018","journal-title":"Lancet Psychiatry"},{"key":"10.1016\/j.bpsc.2020.09.010_bib3","unstructured":"WHO. Alcohol. Available at: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/alcohol. Accessed April 1, 2020."},{"key":"10.1016\/j.bpsc.2020.09.010_bib4","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/npp.2009.110","article-title":"Neurocircuitry of addiction","volume":"35","author":"Koob","year":"2010","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bpsc.2020.09.010_bib5","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/S2215-0366(16)00104-8","article-title":"Neurobiology of addiction: A neurocircuitry analysis","volume":"3","author":"Koob","year":"2016","journal-title":"Lancet Psychiatry"},{"key":"10.1016\/j.bpsc.2020.09.010_bib6","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0893-133X(00)00195-0","article-title":"Drug addiction, dysregulation of reward, and allostasis","volume":"24","author":"Koob","year":"2001","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bpsc.2020.09.010_bib7","doi-asserted-by":"crossref","first-page":"95","DOI":"10.35946\/arcr.v38.1.12","article-title":"Drinking over the lifespan: Focus on early adolescents and youth","volume":"38","author":"Windle","year":"2016","journal-title":"Alcohol Res"},{"key":"10.1016\/j.bpsc.2020.09.010_bib8","doi-asserted-by":"crossref","first-page":"5623683","DOI":"10.1155\/2018\/5623683","article-title":"Neurobiological effects of binge drinking help in its detection and differential diagnosis from alcohol dependence","volume":"2018","author":"Waszkiewicz","year":"2018","journal-title":"Disease Markers"},{"key":"10.1016\/j.bpsc.2020.09.010_bib9","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1126\/science.282.5387.298","article-title":"Transition from moderate to excessive drug intake: Change in hedonic set point","volume":"282","author":"Ahmed","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.bpsc.2020.09.010_bib10","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.neubiorev.2018.09.008","article-title":"Addiction and stress: An allostatic view","volume":"106","author":"Koob","year":"2019","journal-title":"Neurosci Biobehav Rev"},{"issue":"Suppl 1","key":"10.1016\/j.bpsc.2020.09.010_bib11","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.neuropharm.2008.05.022","article-title":"Imaging dopamine\u2019s role in drug abuse and addiction","volume":"56","author":"Volkow","year":"2009","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.bpsc.2020.09.010_bib12","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1126\/science.aay1186","article-title":"A\u00a0cortical-brainstem circuit predicts and governs compulsive alcohol drinking","volume":"366","author":"Siciliano","year":"2019","journal-title":"Science"},{"key":"10.1016\/j.bpsc.2020.09.010_bib13","series-title":"Encyclopedia of Clinical Psychology","article-title":"NIMH Research Domain Criteria (RDoC)","author":"Sanislow","year":"2015"},{"key":"10.1016\/j.bpsc.2020.09.010_bib14","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1176\/appi.ajp.2018.18030357","article-title":"Neurofunctional domains derived from deep behavioral phenotyping in alcohol use disorder","volume":"176","author":"Kwako","year":"2019","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.bpsc.2020.09.010_bib15","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1001\/jamapsychiatry.2016.3084","article-title":"Disruption of reward processing in addiction: An image-based meta-analysis of functional magnetic resonance imaging studies","volume":"74","author":"Luijten","year":"2017","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.bpsc.2020.09.010_bib16","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.conb.2013.03.011","article-title":"Negative reinforcement in drug addiction: The darkness within","volume":"23","author":"Koob","year":"2013","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.bpsc.2020.09.010_bib17","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1038\/nature05051","article-title":"Dopamine-dependent prediction errors underpin reward-seeking behaviour in humans","volume":"442","author":"Pessiglione","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.bpsc.2020.09.010_bib18","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1038\/npp.2013.289","article-title":"Abnormal brain activity during a reward and loss task in opiate-dependent patients receiving methadone maintenance therapy","volume":"39","author":"Gradin","year":"2014","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bpsc.2020.09.010_bib19","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1093\/brain\/awr059","article-title":"Expected value and prediction error abnormalities in depression and schizophrenia","volume":"134","author":"Gradin","year":"2011","journal-title":"Brain"},{"key":"10.1016\/j.bpsc.2020.09.010_bib20","doi-asserted-by":"crossref","first-page":"2539","DOI":"10.1073\/pnas.1416639112","article-title":"Belief about nicotine selectively modulates value and reward prediction error signals in smokers","volume":"112","author":"Gu","year":"2015","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"Pt B","key":"10.1016\/j.bpsc.2020.09.010_bib21","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.neuropharm.2013.05.024","article-title":"Addiction as a stress surfeit disorder","volume":"76","author":"Koob","year":"2014","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.bpsc.2020.09.010_bib22","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.pnmrs.2011.06.001","article-title":"In\u00a0vivo magnetic resonance spectroscopy of GABA: A methodological review","volume":"60","author":"Puts","year":"2012","journal-title":"Prog Nucl Magn Reson Spectrosc"},{"key":"10.1016\/j.bpsc.2020.09.010_bib23","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1038\/nn.3140","article-title":"A\u00a0mechanism for value-guided choice based on the excitation-inhibition balance in prefrontal cortex","volume":"15","author":"Jocham","year":"2012","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.bpsc.2020.09.010_bib24","doi-asserted-by":"crossref","first-page":"18120","DOI":"10.1073\/pnas.1109322108","article-title":"Transformation of stimulus value signals into motor commands during simple choice","volume":"108","author":"Hare","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.bpsc.2020.09.010_bib25","doi-asserted-by":"crossref","first-page":"13524","DOI":"10.1523\/JNEUROSCI.2469-09.2009","article-title":"Human reinforcement learning subdivides structured action spaces by learning effector-specific values","volume":"29","author":"Gershman","year":"2009","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.bpsc.2020.09.010_bib26","doi-asserted-by":"crossref","first-page":"2766","DOI":"10.1093\/brain\/awv177","article-title":"Failure of hippocampal deactivation during loss events in treatment-resistant depression","volume":"138","author":"Johnston","year":"2015","journal-title":"Brain"},{"year":"1999","series-title":"The Brain and Emotion","author":"Rolls","key":"10.1016\/j.bpsc.2020.09.010_bib27"},{"year":"1979","series-title":"Cognitive Theory of Depression","author":"Beck","key":"10.1016\/j.bpsc.2020.09.010_bib28"},{"key":"10.1016\/j.bpsc.2020.09.010_bib29","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1146\/annurev.psych.59.103006.093548","article-title":"Addiction and the brain antireward system","volume":"59","author":"Koob","year":"2008","journal-title":"Annu Rev Psychol"},{"year":"2000","series-title":"The Neuropsychology of Anxiety: An Enquiry into the Functions of the Septo-Hippocampal System","author":"Gray","key":"10.1016\/j.bpsc.2020.09.010_bib30"},{"key":"10.1016\/j.bpsc.2020.09.010_bib32","first-page":"75","article-title":"Distinct prefrontal cortex activity associated with item memory and source memory for visual shapes","volume":"17","author":"Slotnick","year":"2003","journal-title":"Brain Res"},{"key":"10.1016\/j.bpsc.2020.09.010_bib33","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1093\/scan\/nsm006","article-title":"Region of interest analysis for fMRI","volume":"2","author":"Poldrack","year":"2007","journal-title":"Soc Cogn Affect Neurosci"},{"key":"10.1016\/j.bpsc.2020.09.010_bib34","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.neuroimage.2012.12.004","article-title":"Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA","volume":"86","author":"Mullins","year":"2014","journal-title":"Neuroimage"},{"key":"10.1016\/j.bpsc.2020.09.010_bib35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/jmrb.1994.1048","article-title":"WET, a T1- and B1-insensitive water-suppression method for in\u00a0vivo localized 1H NMR spectroscopy","volume":"104","author":"Ogg","year":"1994","journal-title":"J\u00a0Magn Reson B"},{"key":"10.1016\/j.bpsc.2020.09.010_bib36","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1038\/nrn3119","article-title":"Dysfunction of the prefrontal cortex in addiction: Neuroimaging findings and clinical implications","volume":"12","author":"Goldstein","year":"2011","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.bpsc.2020.09.010_bib37","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1177\/0269881113503508","article-title":"The origins of \u20185-HT and mechanisms of defence\u2019 by Deakin and Graeff: A personal perspective","volume":"27","author":"Deakin","year":"2013","journal-title":"J\u00a0Psychopharmacol"},{"key":"10.1016\/j.bpsc.2020.09.010_bib38","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1038\/nrn2994","article-title":"The integration of negative affect, pain and cognitive control in the cingulate cortex","volume":"12","author":"Shackman","year":"2011","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.bpsc.2020.09.010_bib39","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/j.biopsych.2007.07.019","article-title":"Anterior cingulotomy for major depression: Clinical outcome and relationship to lesion characteristics","volume":"63","author":"Steele","year":"2008","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.bpsc.2020.09.010_bib40","doi-asserted-by":"crossref","first-page":"1844","DOI":"10.1093\/brain\/aww069","article-title":"A\u00a0causal role for the anterior mid-cingulate cortex in negative affect and cognitive control","volume":"139","author":"Tolomeo","year":"2016","journal-title":"Brain"},{"key":"10.1016\/j.bpsc.2020.09.010_bib41","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1093\/nsr\/nwz207","article-title":"Neurosurgical treatment for addiction: Lessons from an untold story in China and a path forward","volume":"7","author":"Ma","year":"2020","journal-title":"Natl Sci Rev"},{"key":"10.1016\/j.bpsc.2020.09.010_bib42","doi-asserted-by":"crossref","first-page":"E883","DOI":"10.1227\/NEU.0000000000001248","article-title":"Anterior cingulate implant for alcohol dependence: Case report","volume":"78","author":"De Ridder","year":"2016","journal-title":"Neurosurgery"},{"key":"10.1016\/j.bpsc.2020.09.010_bib43","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/0005-7967(90)90157-E","article-title":"Substance abuse and panic-related anxiety: A critical review","volume":"28","author":"Cox","year":"1990","journal-title":"Behav Res Ther"},{"key":"10.1016\/j.bpsc.2020.09.010_bib44","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1093\/alcalc\/agg055","article-title":"Changes in plasma noradrenaline and serotonin levels and craving during alcohol withdrawal","volume":"38","author":"Patkar","year":"2003","journal-title":"Alcohol Alcohol"},{"key":"10.1016\/j.bpsc.2020.09.010_bib45","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1176\/ajp.155.11.1544","article-title":"Reduced central serotonin transporters in alcoholism","volume":"155","author":"Heinz","year":"1998","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.bpsc.2020.09.010_bib46","doi-asserted-by":"crossref","first-page":"7761","DOI":"10.1523\/JNEUROSCI.0483-18.2018","article-title":"Central amygdala circuits mediate hyperalgesia in alcohol-dependent rats","volume":"38","author":"Avegno","year":"2018","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.bpsc.2020.09.010_bib47","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.tins.2019.03.004","article-title":"Periaqueductal gray sheds light on dark areas of psychopathology","volume":"42","author":"George","year":"2019","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.bpsc.2020.09.010_bib48","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.pscychresns.2017.03.001","article-title":"Gender dimorphism of brain reward system volumes in alcoholism","volume":"263","author":"Sawyer","year":"2017","journal-title":"Psychiatry Res Neuroimaging"},{"key":"10.1016\/j.bpsc.2020.09.010_bib49","doi-asserted-by":"crossref","first-page":"2367","DOI":"10.1093\/brain\/awm150","article-title":"Blunted response to feedback information in depressive illness","volume":"130","author":"Steele","year":"2007","journal-title":"Brain"},{"key":"10.1016\/j.bpsc.2020.09.010_bib50","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1093\/brain\/awn136","article-title":"Abnormal temporal difference reward-learning signals in major depression","volume":"131","author":"Kumar","year":"2008","journal-title":"Brain"},{"key":"10.1016\/j.bpsc.2020.09.010_bib51","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1093\/brain\/awaa106","article-title":"Blunted medial prefrontal cortico-limbic reward-related effective connectivity and depression","volume":"143","author":"Rupprechter","year":"2020","journal-title":"Brain"},{"key":"10.1016\/j.bpsc.2020.09.010_bib52","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0132958","article-title":"Structural MRI-based predictions in patients with treatment-refractory depression (TRD)","volume":"10","author":"Johnston","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.bpsc.2020.09.010_bib53","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1007\/s11920-013-0352-9","article-title":"The long-term impact of early adversity on late-life psychiatric disorders","volume":"15","author":"Gershon","year":"2013","journal-title":"Curr Psychiatry Rep"},{"key":"10.1016\/j.bpsc.2020.09.010_bib54","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1038\/s41398-017-0032-3","article-title":"Early-life adversity and cortisol response to social stress: Aa meta-analysis","volume":"7","author":"Bunea","year":"2017","journal-title":"Transl Psychiatry"},{"key":"10.1016\/j.bpsc.2020.09.010_bib55","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s00406-017-0775-0","article-title":"Understanding gene x early adversity interactions: Possibilities for insight in the biology of psychiatric disorders","volume":"267","author":"Binder","year":"2017","journal-title":"Eur Arch Psychiatry Clin Neurosci"},{"key":"10.1016\/j.bpsc.2020.09.010_bib56","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1176\/appi.ajp.2013.12091257","article-title":"Reduced neural tracking of prediction error in substance-dependent individuals","volume":"170","author":"Tanabe","year":"2013","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.bpsc.2020.09.010_bib57","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1037\/h0036128","article-title":"An opponent-process theory of motivation. I. Temporal dynamics of affect","volume":"81","author":"Solomon","year":"1974","journal-title":"Psychol Rev"},{"key":"10.1016\/j.bpsc.2020.09.010_bib58","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1037\/0003-066X.35.8.691","article-title":"The opponent-process theory of acquired motivation\u2014the costs of pleasure and the benefits of pain","volume":"35","author":"Solomon","year":"1980","journal-title":"Am Psychol"},{"key":"10.1016\/j.bpsc.2020.09.010_bib59","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1097\/01.ALC.0000057122.36127.C2","article-title":"Alcoholism: Allostasis and beyond","volume":"27","author":"Koob","year":"2003","journal-title":"Alcohol Clin Exp Res"},{"key":"10.1016\/j.bpsc.2020.09.010_bib60","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.bbr.2013.07.011","article-title":"Alterations in affective behavior during the time course of alcohol hangover","volume":"253","author":"Karadayian","year":"2013","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.bpsc.2020.09.010_bib61","doi-asserted-by":"crossref","first-page":"72","DOI":"10.3389\/fpsyt.2013.00072","article-title":"Addiction is a reward deficit and stress surfeit disorder","volume":"4","author":"Koob","year":"2013","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.bpsc.2020.09.010_bib62","series-title":"Neurobiology of Addiction, Volume 1: Introduction to Addiction: Addiction, Animal Models, and Theories","article-title":"What is addiction?","author":"Koob","year":"2019"}],"container-title":["Biological Psychiatry: Cognitive Neuroscience and Neuroimaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451902220302792?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451902220302792?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T13:14:31Z","timestamp":1762521271000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2451902220302792"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":60,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["S2451902220302792"],"URL":"https:\/\/doi.org\/10.1016\/j.bpsc.2020.09.010","relation":{},"ISSN":["2451-9022"],"issn-type":[{"type":"print","value":"2451-9022"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Alcohol Binge Drinking: Negative and Positive Valence System Abnormalities","name":"articletitle","label":"Article Title"},{"value":"Biological Psychiatry: Cognitive Neuroscience and Neuroimaging","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bpsc.2020.09.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}