{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T06:28:08Z","timestamp":1790144888206,"version":"4.0.1"},"reference-count":48,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,1,12]],"date-time":"2021-01-12T00:00:00Z","timestamp":1610409600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000833","name":"Rosetrees Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000833","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000887","name":"Huntington's Disease Society of America","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000887","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003068","name":"\u00c9cole Sup\u00e9rieure de Physique et de Chimie Industrielles de la Ville de Paris","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003068","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005725","name":"CHDI Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003135","name":"Fondation Fyssen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003135","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009670","name":"National Alliance for Research on Schizophrenia and Depression","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009670","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012091","name":"NIHR Clinical Research Network Thames Valley and South Midlands","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012091","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["200181\/Z\/15\/Z"],"award-info":[{"award-number":["200181\/Z\/15\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["203147\/Z\/16\/Z"],"award-info":[{"award-number":["203147\/Z\/16\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012616","name":"Fondation Schlumberger pour l\u2019Education et la Recherche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012616","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/N02401X\/1"],"award-info":[{"award-number":["MR\/N02401X\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000874","name":"Brain and Behavior Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000874","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017510","name":"UK Dementia Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100017510","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biological Psychiatry: Cognitive Neuroscience and Neuroimaging"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.bpsc.2020.12.015","type":"journal-article","created":{"date-parts":[[2021,1,14]],"date-time":"2021-01-14T17:21:13Z","timestamp":1610644873000},"page":"910-918","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Aberrant Striatal Value Representation in Huntington's Disease Gene Carriers 25 Years Before Onset"],"prefix":"10.1016","volume":"6","author":[{"given":"Akshay","family":"Nair","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eileanoir B.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Gregory","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Osborne-Crowley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6470-7169","authenticated-orcid":false,"given":"Paul","family":"Zeun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1832-106X","authenticated-orcid":false,"given":"Rachael I.","family":"Scahill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Lowe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0971-8361","authenticated-orcid":false,"given":"Marina","family":"Papoutsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Palminteri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robb B.","family":"Rutledge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9623-7007","authenticated-orcid":false,"given":"Geraint","family":"Rees","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah J.","family":"Tabrizi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bpsc.2020.12.015_bib1","series-title":"Polyglutamine Disorders. Advances in Experimental Medicine and Biology, vol. 1049","first-page":"1","article-title":"Clinical features of Huntington\u2019s Disease","author":"Ghosh","year":"2018"},{"key":"10.1016\/j.bpsc.2020.12.015_bib2","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1136\/jnnp-2013-307343","article-title":"Neuropsychiatric symptoms in a European Huntington\u2019s disease cohort (REGISTRY)","volume":"85","author":"Duijn","year":"2014","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.bpsc.2020.12.015_bib3","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/0092-8674(93)90585-E","article-title":"A\u00a0novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington\u2019s disease chromosomes","volume":"72","author":"MacDonald","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.bpsc.2020.12.015_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/nrdp.2015.5","article-title":"Huntington disease","volume":"1","author":"Bates","year":"2015","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.bpsc.2020.12.015_bib5","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1002\/ajmg.b.30992","article-title":"CAG-repeat length and the age of onset in Huntington disease (HD): A review and validation study of statistical approaches","volume":"153B","author":"Langbehn","year":"2010","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"10.1016\/j.bpsc.2020.12.015_bib6","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S1474-4422(10)70276-3","article-title":"Biological and clinical changes in premanifest and early stage Huntington\u2019s disease in the TRACK-HD study: The 12-month longitudinal analysis","volume":"10","author":"Tabrizi","year":"2011","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.bpsc.2020.12.015_bib7","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1038\/nrneurol.2014.24","article-title":"Huntington disease: Natural history, biomarkers and prospects for therapeutics","volume":"10","author":"Ross","year":"2014","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.bpsc.2020.12.015_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1037\/a0020937","article-title":"Neurocognitive signs in prodromal Huntington disease","volume":"25","author":"Stout","year":"2011","journal-title":"Neuropsychology"},{"key":"10.1016\/j.bpsc.2020.12.015_bib9","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1056\/NEJMoa1900907","article-title":"Targeting Huntingtin expression in patients with Huntington\u2019s disease","volume":"380","author":"Tabrizi","year":"2019","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.bpsc.2020.12.015_bib10","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/S1474-4422(17)30280-6","article-title":"Therapies targeting DNA and RNA in Huntington\u2019s disease","volume":"16","author":"Wild","year":"2017","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.bpsc.2020.12.015_bib11","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1007\/s11910-011-0215-x","article-title":"Cognitive impairment in Huntington disease: Diagnosis and treatment","volume":"11","author":"Paulsen","year":"2011","journal-title":"Curr Neurol Neurosci Rep"},{"key":"10.1016\/j.bpsc.2020.12.015_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2741\/S355","article-title":"A\u00a0review of cognition in Huntington\u2019s disease","volume":"5","author":"Dumas","year":"2013","journal-title":"Front Biosci (Schol Ed)"},{"key":"10.1016\/j.bpsc.2020.12.015_bib13","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1093\/arclin\/acx086","article-title":"The neuropsychology of Huntington\u2019s disease","volume":"32","author":"Snowden","year":"2017","journal-title":"Arch Clin Neuropsychol"},{"key":"10.1016\/j.bpsc.2020.12.015_bib14","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/7854_2014_354","article-title":"The neuropathology of Huntington\u2019s disease","volume":"22","author":"Waldvogel","year":"2015","journal-title":"Curr Top Behav Neurosci"},{"key":"10.1016\/j.bpsc.2020.12.015_bib15","doi-asserted-by":"crossref","first-page":"301","DOI":"10.4329\/wjr.v6.i6.301","article-title":"Neuroimaging in Huntington\u2019s disease","volume":"6","author":"Niccolini","year":"2014","journal-title":"World J Radiol"},{"key":"10.1016\/j.bpsc.2020.12.015_bib16","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1038\/nn.3743","article-title":"Direct and indirect pathways of basal ganglia: A critical reappraisal","volume":"17","author":"Calabresi","year":"2014","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.bpsc.2020.12.015_bib17","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3389\/fnana.2011.00059","article-title":"Basal ganglia disorders associated with imbalances in the striatal striosome and matrix compartments","volume":"5","author":"Crittenden","year":"2011","journal-title":"Front Neuroanat"},{"key":"10.1016\/j.bpsc.2020.12.015_bib18","doi-asserted-by":"crossref","first-page":"a021691","DOI":"10.1101\/cshperspect.a021691","article-title":"The striatum: Where skills and habits meet","volume":"7","author":"Graybiel","year":"2015","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"10.1016\/j.bpsc.2020.12.015_bib19","series-title":"Neurobiology of Sensation and Reward. Frontiers in Neuroscience","first-page":"235","article-title":"Neuroanatomy of reward: A view from the ventral striatum","author":"Haber","year":"2011"},{"key":"10.1016\/j.bpsc.2020.12.015_bib20","doi-asserted-by":"crossref","first-page":"7","DOI":"10.31887\/DCNS.2016.18.1\/shaber","article-title":"Corticostriatal circuitry","volume":"18","author":"Haber","year":"2016","journal-title":"Dialogues Clin Neurosci"},{"key":"10.1016\/j.bpsc.2020.12.015_bib21","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1007\/s11065-018-9385-5","article-title":"The neural substrate of reward anticipation in health: A meta-analysis of fMRI findings in the monetary incentive delay task [published correction appears in Neuropsychol Rev 28:507\u2013508]","volume":"28","author":"Wilson","year":"2018","journal-title":"Neuropsychol Rev"},{"key":"10.1016\/j.bpsc.2020.12.015_bib22","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1007\/s11682-016-9660-0","article-title":"Reversal learning reveals cognitive deficits and altered prediction error encoding in the ventral striatum in Huntington\u2019s disease","volume":"11","author":"Nickchen","year":"2016","journal-title":"Brain Imaging Behav"},{"key":"10.1016\/j.bpsc.2020.12.015_bib23","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/j.neuron.2012.10.017","article-title":"Critical roles for anterior insula and dorsal striatum in punishment-based avoidance learning","volume":"76","author":"Palminteri","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.bpsc.2020.12.015_bib24","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.expneurol.2012.02.003","article-title":"Altered ventral striatal activation during reward and punishment processing in premanifest Huntington\u2019s disease: A functional magnetic resonance study","volume":"235","author":"Enzi","year":"2012","journal-title":"Exp Neurol"},{"key":"10.1016\/j.bpsc.2020.12.015_bib25","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1080\/13554794.2013.873063","article-title":"Reward processing in neurodegenerative disease","volume":"21","author":"Perry","year":"2015","journal-title":"Neurocase"},{"key":"10.1016\/j.bpsc.2020.12.015_bib26","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1017\/S1355617715001241","article-title":"The allure of high-risk rewards in Huntington\u2019s disease","volume":"22","author":"van Wouwe","year":"2016","journal-title":"J\u00a0Int Neuropsychol Soc"},{"key":"10.1016\/j.bpsc.2020.12.015_bib27","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.nlm.2014.05.002","article-title":"A\u00a0universal role of the ventral striatum in reward-based learning: Evidence from human studies","volume":"114","author":"Daniel","year":"2014","journal-title":"Neurobiol Learn Mem"},{"key":"10.1016\/j.bpsc.2020.12.015_bib28","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1016\/j.neubiorev.2010.12.012","article-title":"Common and distinct networks underlying reward valence and processing stages: A meta-analysis of functional neuroimaging studies","volume":"35","author":"Liu","year":"2011","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.bpsc.2020.12.015_bib29","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1038\/nature05051","article-title":"Dopamine-dependent prediction errors underpin reward-seeking behaviour in humans","volume":"442","author":"Pessiglione","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.bpsc.2020.12.015_bib30","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0893-6080(02)00047-3","article-title":"Actor-critic models of the basal ganglia: New anatomical and computational perspectives","volume":"15","author":"Joel","year":"2002","journal-title":"Neural Netw"},{"key":"10.1016\/j.bpsc.2020.12.015_bib31","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1037\/a0037015","article-title":"Opponent actor learning (OpAL): Modeling interactive effects of striatal dopamine on reinforcement learning and choice incentive","volume":"121","author":"Collins","year":"2014","journal-title":"Psychol Rev"},{"key":"10.1016\/j.bpsc.2020.12.015_bib32","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.12029","article-title":"A\u00a0cholinergic feedback circuit to regulate striatal population uncertainty and optimize reinforcement learning","volume":"4","author":"Franklin","year":"2015","journal-title":"Elife"},{"key":"10.1016\/j.bpsc.2020.12.015_bib33","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1002\/ana.410310412","article-title":"Preferential loss of striato-external pallidal projection neurons in presymptomatic Huntington\u2019s disease","volume":"31","author":"Albin","year":"1992","journal-title":"Ann Neurol"},{"key":"10.1016\/j.bpsc.2020.12.015_bib34","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.jchemneu.2004.02.005","article-title":"Differential loss of striatal projection systems in Huntington\u2019s disease: A quantitative immunohistochemical study","volume":"27","author":"Deng","year":"2004","journal-title":"J\u00a0Chem Neuroanat"},{"key":"10.1016\/j.bpsc.2020.12.015_bib35","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1038\/nature17400","article-title":"Nucleus accumbens D2R cells signal prior outcomes and control risky decision-making","volume":"531","author":"Zalocusky","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.bpsc.2020.12.015_bib36","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.neuron.2010.05.011","article-title":"Distinct roles of synaptic transmission in direct and indirect striatal pathways to reward and aversive behavior","volume":"66","author":"Hikida","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.bpsc.2020.12.015_bib37","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1073\/pnas.1220358110","article-title":"Pathway-specific modulation of nucleus accumbens in reward and aversive behavior via selective transmitter receptors","volume":"110","author":"Hikida","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.bpsc.2020.12.015_bib38","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/S1474-4422(20)30143-5","article-title":"Biological and clinical characteristics of gene carriers far from predicted onset in the Huntington\u2019s Disease Young Adult Study (HD-YAS): A cross-sectional analysis","volume":"19","author":"Scahill","year":"2020","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.bpsc.2020.12.015_bib39","series-title":"Reinforcement Learning: An Introduction, 2nd ed","author":"Sutton","year":"2012"},{"key":"10.1016\/j.bpsc.2020.12.015_bib40","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.neuroimage.2006.07.029","article-title":"Optimal EPI parameters for reduction of susceptibility-induced BOLD sensitivity losses: A whole-brain analysis at 3 T and 1.5 T","volume":"33","author":"Weiskopf","year":"2006","journal-title":"Neuroimage"},{"key":"10.1016\/j.bpsc.2020.12.015_bib41","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1093\/brain\/awx025","article-title":"Neural mechanisms of reinforcement learning in unmedicated patients with major depressive disorder","volume":"140","author":"Rothkirch","year":"2017","journal-title":"Brain"},{"key":"10.1016\/j.bpsc.2020.12.015_bib42","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1004237","article-title":"Is model fitting necessary for model-based fMRI?","volume":"11","author":"Wilson","year":"2015","journal-title":"PLoS Comput Biol"},{"key":"10.1016\/j.bpsc.2020.12.015_bib43","doi-asserted-by":"crossref","first-page":"12860","DOI":"10.1523\/JNEUROSCI.2496-07.2007","article-title":"Reinforcement Learning signals in the human striatum distinguish learners from nonlearners during reward-based decision making","volume":"27","author":"Schonberg","year":"2007","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.bpsc.2020.12.015_bib44","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1038\/nn.3842","article-title":"Mind matters: Placebo enhances reward learning in Parkinson\u2019s disease","volume":"17","author":"Schmidt","year":"2014","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.bpsc.2020.12.015_bib45","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.bbr.2015.10.001","article-title":"Social cognition in\u00a0Huntington\u2019s disease: A meta-analysis","volume":"297","author":"Bora","year":"2016","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.bpsc.2020.12.015_bib46","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.neubiorev.2011.06.002","article-title":"Emotion recognition in Huntington\u2019s disease: A systematic review","volume":"36","author":"Henley","year":"2012","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.bpsc.2020.12.015_bib47","doi-asserted-by":"crossref","first-page":"114","DOI":"10.3389\/fnins.2013.00114","article-title":"Dopamine imbalance in Huntington\u2019s disease: A mechanism for the lack of behavioral flexibility","volume":"7","author":"Chen","year":"2013","journal-title":"Front Neurosci"},{"key":"10.1016\/j.bpsc.2020.12.015_bib48","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.neuron.2009.12.027","article-title":"Mechanisms underlying dopamine-mediated reward bias in compulsive behaviors","volume":"65","author":"Voon","year":"2011","journal-title":"Neuron"}],"container-title":["Biological Psychiatry: Cognitive Neuroscience and Neuroimaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451902221000045?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451902221000045?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T13:15:34Z","timestamp":1762521334000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2451902221000045"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":48,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["S2451902221000045"],"URL":"https:\/\/doi.org\/10.1016\/j.bpsc.2020.12.015","relation":{},"ISSN":["2451-9022"],"issn-type":[{"value":"2451-9022","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aberrant Striatal Value Representation in Huntington's Disease Gene Carriers 25 Years Before Onset","name":"articletitle","label":"Article Title"},{"value":"Biological Psychiatry: Cognitive Neuroscience and Neuroimaging","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bpsc.2020.12.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Society of Biological Psychiatry. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}