{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T01:46:14Z","timestamp":1788399974192,"version":"build-2803163510"},"reference-count":35,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T00:00:00Z","timestamp":1731283200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biological Psychiatry: Cognitive Neuroscience and Neuroimaging"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.bpsc.2024.10.020","type":"journal-article","created":{"date-parts":[[2024,11,14]],"date-time":"2024-11-14T10:53:13Z","timestamp":1731581593000},"page":"295-303","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Increased Amygdala Activation During Symptom Provocation Predicts Response to Combined Repetitive Transcranial Magnetic Stimulation and Exposure Therapy in Obsessive-Compulsive Disorder in a Randomized Controlled Trial"],"prefix":"10.1016","volume":"10","author":[{"given":"Milan","family":"Houben","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6497-9113","authenticated-orcid":false,"given":"Tjardo S.","family":"Postma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie M.D.D.","family":"Fitzsimmons","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Vriend","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neeltje M.","family":"Batelaan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriaan W.","family":"Hoogendoorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ysbrand D.","family":"van der Werf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Odile A.","family":"van den Heuvel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bpsc.2024.10.020_bib1","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1038\/s41572-019-0102-3","article-title":"Obsessive\u2013compulsive disorder","volume":"5","author":"Stein","year":"2019","journal-title":"Nat Rev Dis Primers"},{"issue":"suppl 1","key":"10.1016\/j.bpsc.2024.10.020_bib2","first-page":"S85","article-title":"Exposure and response prevention for obsessive\u2013compulsive disorder: A review and new directions","volume":"61","author":"Hezel","year":"2019","journal-title":"Indian J Psychiatry"},{"key":"10.1016\/j.bpsc.2024.10.020_bib3","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1001\/jama.2017.2200","article-title":"Obsessive\u2013compulsive disorder: Advances in diagnosis and treatment","volume":"317","author":"Hirschtritt","year":"2017","journal-title":"JAMA"},{"key":"10.1016\/j.bpsc.2024.10.020_bib4","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/S2215-0366(16)30069-4","article-title":"Pharmacological and psychotherapeutic interventions for management of obsessive\u2013compulsive disorder in adults: A systematic review and network meta-analysis","volume":"3","author":"Skapinakis","year":"2016","journal-title":"Lancet Psychiatry"},{"key":"10.1016\/j.bpsc.2024.10.020_bib5","doi-asserted-by":"crossref","first-page":"5647","DOI":"10.2174\/0929867325666171222163645","article-title":"A\u00a0Systematic Review of Evidence-based Treatment Strategies for obsessive- compulsive Disorder Resistant to first-line Pharmacotherapy","volume":"25","author":"Albert","year":"2018","journal-title":"Curr Med Chem"},{"key":"10.1016\/j.bpsc.2024.10.020_bib6","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.jad.2022.01.048","article-title":"Repetitive transcranial magnetic stimulation for obsessive\u2013compulsive disorder: A systematic review and pairwise\/network meta-analysis","volume":"302","author":"Fitzsimmons","year":"2022","journal-title":"J\u00a0Affect Disord"},{"key":"10.1016\/j.bpsc.2024.10.020_bib7","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1016\/j.clinph.2009.08.016","article-title":"Safety, ethical considerations, and application guidelines for the use of transcranial magnetic stimulation in clinical practice and research","volume":"120","author":"Rossi","year":"2009","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.bpsc.2024.10.020_bib8","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/j.euroneuro.2015.12.005","article-title":"Brain circuitry of compulsivity","volume":"26","author":"van den Heuvel","year":"2016","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/j.bpsc.2024.10.020_bib9","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1001\/archpsyc.64.8.946","article-title":"Functional and biochemical alterations of the medial frontal cortex in obsessive\u2013compulsive disorder","volume":"64","author":"Y\u00fccel","year":"2007","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.bpsc.2024.10.020_bib10","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/j.jpsychires.2013.03.022","article-title":"Repetitive transcranial magnetic stimulation (rTMS) for obsessive\u2013compulsive disorder (OCD): An exploratory meta-analysis of randomized and sham-controlled trials","volume":"47","author":"Berlim","year":"2013","journal-title":"J\u00a0Psychiatr Res"},{"key":"10.1016\/j.bpsc.2024.10.020_bib11","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1017\/S0033291713002766","article-title":"Predicting response to cognitive behavioral therapy in contamination-based obsessive\u2013compulsive disorder from\u00a0functional magnetic resonance imaging","volume":"44","author":"Olatunji","year":"2014","journal-title":"Psychol Med"},{"key":"10.1016\/j.bpsc.2024.10.020_bib12","doi-asserted-by":"crossref","first-page":"3387","DOI":"10.1017\/S0033291721005444","article-title":"Neural predictors of cognitive-behavior therapy outcome in anxiety-related disorders: A meta-analysis of task-based fMRI studies","volume":"53","author":"Pic\u00f3-P\u00e9rez","year":"2023","journal-title":"Psychol Med"},{"key":"10.1016\/j.bpsc.2024.10.020_bib13","first-page":"678","article-title":"Transcranial magnetic stimulation\u2013induced plasticity improving cognitive control in obsessive-compulsive disorder, Part I: Clinical and neuroimaging outcomes from a randomized trial","volume":"97","author":"Fitzsimmons","year":"2025","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.bpsc.2024.10.020_bib14","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1016\/j.neubiorev.2011.12.014","article-title":"Neural and cellular mechanisms of fear and extinction memory formation","volume":"36","author":"Orsini","year":"2012","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.bpsc.2024.10.020_bib15","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1176\/appi.ajp.2012.12010073","article-title":"Presupplementary motor area hyperactivity during response inhibition: A candidate endophenotype of obsessive-compulsive disorder","volume":"169","author":"de Wit","year":"2012","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.bpsc.2024.10.020_bib16","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1001\/archpsyc.1989.01810110048007","article-title":"The Yale-Brown Obsessive Compulsive Scale. I. Development, use, and reliability","volume":"46","author":"Goodman","year":"1989","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.bpsc.2024.10.020_bib17","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0028-3932(71)90067-4","article-title":"The assessment and analysis of handedness: The Edinburgh inventory","volume":"9","author":"Oldfield","year":"1971","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.bpsc.2024.10.020_bib18","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1001\/archpsyc.1961.01710120031004","article-title":"An inventory for measuring depression","volume":"4","author":"Beck","year":"1961","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.bpsc.2024.10.020_bib19","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1037\/0022-006X.56.6.893","article-title":"An inventory for measuring clinical anxiety: Psychometric properties","volume":"56","author":"Beck","year":"1988","journal-title":"J\u00a0Consult Clin Psychol"},{"key":"10.1016\/j.bpsc.2024.10.020_bib20","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1037\/0022-3514.85.2.348","article-title":"Individual differences in two emotion regulation processes: Implications for affect, relationships, and well-being","volume":"85","author":"Gross","year":"2003","journal-title":"J\u00a0Pers Soc Psychol"},{"key":"10.1016\/j.bpsc.2024.10.020_bib21","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1002\/wps.20299","article-title":"Towards an international expert consensus for defining treatment response, remission, recovery and relapse in obsessive\u2013compulsive disorder","volume":"15","author":"Mataix-Cols","year":"2016","journal-title":"World Psychiatry"},{"key":"10.1016\/j.bpsc.2024.10.020_bib22","first-page":"61","article-title":"Effectiveness and predictors of response to 1-Hz repetitive transcranial magnetic stimulation in patients with obsessive-compulsive disorder","volume":"35","author":"Singh","year":"2019","journal-title":"J\u00a0ECT"},{"key":"10.1016\/j.bpsc.2024.10.020_bib23","doi-asserted-by":"crossref","first-page":"4583","DOI":"10.1038\/s41380-020-01007-8","article-title":"Toward a neurocircuit-based taxonomy to guide treatment of obsessive\u2013compulsive disorder","volume":"26","author":"Shephard","year":"2021","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.bpsc.2024.10.020_bib24","doi-asserted-by":"crossref","first-page":"3059","DOI":"10.1017\/S0033291715001026","article-title":"Emotion regulation before and after transcranial magnetic stimulation in obsessive compulsive disorder","volume":"45","author":"de Wit","year":"2015","journal-title":"Psychol Med"},{"key":"10.1016\/j.bpsc.2024.10.020_bib25","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1162\/jocn.2009.21309","article-title":"Semantic processing in the anterior temporal lobes: A meta-analysis of the functional neuroimaging literature","volume":"22","author":"Visser","year":"2010","journal-title":"J\u00a0Cogn Neurosci"},{"key":"10.1016\/j.bpsc.2024.10.020_bib26","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.neubiorev.2007.12.002","article-title":"The role of the amygdala in emotional processing: A quantitative meta-analysis of functional neuroimaging studies","volume":"32","author":"Sergerie","year":"2008","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.bpsc.2024.10.020_bib27","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.tics.2011.11.003","article-title":"Obsessive\u2013compulsive disorder: Beyond segregated cortico-striatal pathways","volume":"16","author":"Milad","year":"2012","journal-title":"Trends Cogn Sci"},{"key":"10.1016\/j.bpsc.2024.10.020_bib28","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.psc.2006.02.006","article-title":"Common and distinct neural correlates of obsessive\u2013compulsive and related disorders","volume":"29","author":"Mataix-Cols","year":"2006","journal-title":"Psychiatr Clin North Am"},{"key":"10.1016\/j.bpsc.2024.10.020_bib29","doi-asserted-by":"crossref","first-page":"2871","DOI":"10.1073\/pnas.1400335111","article-title":"Coming to terms with fear","volume":"111","author":"LeDoux","year":"2014","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.bpsc.2024.10.020_bib30","first-page":"688","article-title":"Transcranial magnetic stimulation\u2013induced plasticity improving cognitive control in obsessive-compulsive disorder, Part II: Task-based neural predictors of treatment response","volume":"97","author":"Postma","year":"2025","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.bpsc.2024.10.020_bib31","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1037\/0033-2909.99.1.20","article-title":"Emotional processing of fear: Exposure to corrective information","volume":"99","author":"Foa","year":"1986","journal-title":"Psychol Bull"},{"key":"10.1016\/j.bpsc.2024.10.020_bib32","series-title":"Current Controversies in the Anxiety Disorders","first-page":"214","article-title":"Mechanisms of change in exposure therapy","author":"Foa","year":"1996"},{"key":"10.1016\/j.bpsc.2024.10.020_bib33","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1016\/j.neuroimage.2003.08.011","article-title":"Contributions of stimulus valence and arousal to visual activation during emotional perception","volume":"20","author":"Mour\u00e3o-Miranda","year":"2003","journal-title":"Neuroimage"},{"key":"10.1016\/j.bpsc.2024.10.020_bib34","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1016\/j.clinph.2004.02.005","article-title":"Long-lasting increase in corticospinal excitability after 1800 pulses of subthreshold 5 Hz repetitive TMS to the primary motor cortex","volume":"115","author":"Peinemann","year":"2004","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.bpsc.2024.10.020_bib35","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1212\/WNL.57.3.449","article-title":"Decreased corticospinal excitability after subthreshold 1 Hz rTMS over lateral premotor cortex","volume":"57","author":"Gerschlager","year":"2001","journal-title":"Neurology"}],"updated-by":[{"DOI":"10.1016\/j.bpsc.2025.01.009","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000}}],"container-title":["Biological Psychiatry: Cognitive Neuroscience and Neuroimaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451902224003379?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451902224003379?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T02:28:23Z","timestamp":1741228103000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2451902224003379"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":35,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S2451902224003379"],"URL":"https:\/\/doi.org\/10.1016\/j.bpsc.2024.10.020","relation":{},"ISSN":["2451-9022"],"issn-type":[{"value":"2451-9022","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Increased Amygdala Activation During Symptom Provocation Predicts Response to Combined Repetitive Transcranial Magnetic Stimulation and Exposure Therapy in Obsessive-Compulsive Disorder in a Randomized Controlled Trial","name":"articletitle","label":"Article Title"},{"value":"Biological Psychiatry: Cognitive Neuroscience and Neuroimaging","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bpsc.2024.10.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Society of Biological Psychiatry. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}