{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T23:43:38Z","timestamp":1778802218703,"version":"3.51.4"},"reference-count":25,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2007,10,1]],"date-time":"2007-10-01T00:00:00Z","timestamp":1191196800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,10,1]],"date-time":"2007-10-01T00:00:00Z","timestamp":1191196800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["brachyjournal.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brachytherapy"],"published-print":{"date-parts":[[2007,10]]},"DOI":"10.1016\/j.brachy.2007.08.004","type":"journal-article","created":{"date-parts":[[2007,11,27]],"date-time":"2007-11-27T09:59:56Z","timestamp":1196157596000},"page":"298-303","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Interstitial brachytherapy for soft tissue sarcoma: A single institution experience"],"prefix":"10.1016","volume":"6","author":[{"given":"Michelle L.","family":"Mierzwa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Connie M.","family":"McCluskey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William L.","family":"Barrett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Lowy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey","family":"Sussman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joel","family":"Sorger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.brachy.2007.08.004_bib1","unstructured":"Surveillance, Epidemiology, and End Results (SEER) Program (www.seer.cancer.gov) SEER*Stat Database: Incidence\u2014SEER 9 Regs Public-Use, Nov 2002 Sub (1973\u20132000), National Cancer Institute, DCCPS, Surveillance Research Program, Cancer Statistics Branch, released April 2003, based on the November 2002 submission."},{"key":"10.1016\/j.brachy.2007.08.004_bib2","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1097\/00000658-198209000-00009","article-title":"The treatment of soft-tissue sarcomas of the extremities: Prospective randomized evaluations of (1) limb-sparing surgery plus radiation therapy compared with amputation and (2) the role of adjuvant chemotherapy","volume":"196","author":"Rosenberg","year":"1982","journal-title":"Ann Surg"},{"key":"10.1016\/j.brachy.2007.08.004_bib3","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1200\/JCO.1998.16.1.197","article-title":"Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity","volume":"16","author":"Yang","year":"1998","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.brachy.2007.08.004_bib4","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1200\/JCO.1996.14.3.859","article-title":"Long-term results of a prospective randomized trial of adjuvant brachytherapy in soft tissue sarcoma","volume":"14","author":"Pisters","year":"1996","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.brachy.2007.08.004_bib5","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.ijrobp.2003.10.048","article-title":"Soft tissue sarcomas treated with postoperative external beam radiotherapy with and without low-dose-rate brachytherapy","volume":"59","author":"Andrews","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2007.08.004_bib6","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/S0360-3016(00)00753-7","article-title":"Adjuvant radiotherapy for margin-positive high-grade soft tissue sarcoma of the extremity","volume":"48","author":"Alektiar","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2007.08.004_bib7","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/S0360-3016(03)00714-4","article-title":"Prognostic factors for disease-specific survival after first relapse of soft tissue sarcoma: Analysis of 402 patients with disease relapse after initial conservative surgery and radiotherapy","volume":"57","author":"Zagars","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2007.08.004_bib8","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1007\/s10434-001-0278-z","article-title":"Prognostic index of extremity soft tissue sarcomas with isolated local recurrence","volume":"8","author":"Ramanathan","year":"2001","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.brachy.2007.08.004_bib9","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1002\/1097-0142(19940315)73:6<1652::AID-CNCR2820730617>3.0.CO;2-X","article-title":"Influence of surgical margins on outcome in patients with preoperatively irradiated extremity soft tissue sarcomas","volume":"73","author":"Tanabe","year":"1994","journal-title":"Cancer"},{"key":"10.1016\/j.brachy.2007.08.004_bib10","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/jso.2930520405","article-title":"Preoperative radiation, surgical margins, and local control of extremity sarcomas of soft tissues","volume":"52","author":"Sadoski","year":"1993","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.brachy.2007.08.004_bib11","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1200\/JCO.1996.14.2.473","article-title":"Prognostic significance of a positive microscopic margin in high-risk extremity soft tissue sarcoma: Implications for management","volume":"14","author":"Heslin","year":"1996","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.brachy.2007.08.004_bib12","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1200\/JCO.1996.14.3.869","article-title":"Prognostic factors in adult patients with locally controlled soft tissue sarcoma: A study of 546 patients from the French Federation of Cancer Centers Sarcoma Group","volume":"14","author":"Coindre","year":"1996","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.brachy.2007.08.004_bib13","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/S0360-3016(02)04573-X","article-title":"Significance of dose in postoperative radiotherapy for soft tissue sarcoma","volume":"56","author":"Zagars","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2007.08.004_bib14","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1016\/j.ijrobp.2006.11.035","article-title":"Radiation therapy for control of soft tissue sarcomas resected with positive margins","volume":"67","author":"Delaney","year":"2007","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2007.08.004_bib15","doi-asserted-by":"crossref","first-page":"370","DOI":"10.2106\/00004623-198971030-00010","article-title":"The surgical margin in soft tissue sarcoma","volume":"71","author":"Bell","year":"1989","journal-title":"J Bone Joint Surg"},{"key":"10.1016\/j.brachy.2007.08.004_bib16","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/0360-3016(90)90011-8","article-title":"Post-operative radiotherapy in the treatment of soft tissue sarcomas","volume":"19","author":"Pao","year":"1990","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2007.08.004_bib17","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/0360-3016(93)90529-5","article-title":"Outcome and prognostic factors in soft tissue sarcoma in the adult","volume":"27","author":"Levay","year":"1993","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2007.08.004_bib18","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/j.ijrobp.2006.10.036","article-title":"Management of locally recurrent soft tissue sarcoma after prior surgery and radiation therapy","volume":"67","author":"Torres","year":"2007","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2007.08.004_bib19","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1093\/jjco\/hye050","article-title":"High dose rate interstitial brachytherapy in soft tissue sarcoma: Technical aspects and results","volume":"31","author":"Chun","year":"2001","journal-title":"Jpn J Clin Oncol"},{"key":"10.1016\/j.brachy.2007.08.004_bib20","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1245\/s10434-006-9137-2","article-title":"Perioperative interstitial brachytherapy for soft tissue sarcomas: Prognostic factors and long-term results of 155 patients","volume":"14","author":"Laskar","year":"2007","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.brachy.2007.08.004_bib21","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/0360-3016(90)90012-9","article-title":"Limb salvage in soft tissue sarcomas involving neurovascular structures using combined surgical resection and brachytherapy","volume":"19","author":"Zelefsky","year":"1990","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2007.08.004_bib22","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/BF02409051","article-title":"Wound complications after resection and immediate postoperative brachytherapy in the management of soft tissue sarcomas","volume":"3","author":"Dalton","year":"1996","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.brachy.2007.08.004_bib23","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.radonc.2004.12.020","article-title":"Late radiation morbidity following randomization to preoperative versus postoperative radiotherapy in extremity soft tissue sarcoma","volume":"75","author":"Davis","year":"2005","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.brachy.2007.08.004_bib24","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S0360-3016(96)00331-8","article-title":"The effect of combined external beam radiotherapy and brachytherapy on local control and wound complications in patients with high-grade soft tissue sarcomas of the extremity with positive microscopic margin","volume":"36","author":"Alekhteyar","year":"1996","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2007.08.004_bib25","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1245\/ASO.2005.11.004","article-title":"Pulsed dose-rate perioperative interstitial brachytherapy for soft tissue sarcomas of the extremities and skeletal muscles of the trunk","volume":"12","author":"Lazzaro","year":"2005","journal-title":"Ann Surg Oncol"}],"container-title":["Brachytherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538472107002437?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538472107002437?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T02:03:41Z","timestamp":1761530621000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1538472107002437"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,10]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,10]]}},"alternative-id":["S1538472107002437"],"URL":"https:\/\/doi.org\/10.1016\/j.brachy.2007.08.004","relation":{},"ISSN":["1538-4721"],"issn-type":[{"value":"1538-4721","type":"print"}],"subject":[],"published":{"date-parts":[[2007,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Interstitial brachytherapy for soft tissue sarcoma: A single institution experience","name":"articletitle","label":"Article Title"},{"value":"Brachytherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brachy.2007.08.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}