{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:51:11Z","timestamp":1786985471391,"version":"build-2736575974"},"reference-count":17,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["brachyjournal.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brachytherapy"],"published-print":{"date-parts":[[2015,5]]},"DOI":"10.1016\/j.brachy.2014.12.002","type":"journal-article","created":{"date-parts":[[2015,1,13]],"date-time":"2015-01-13T22:23:43Z","timestamp":1421187823000},"page":"401-404","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["A Phase I study of high-dose-rate intraluminal brachytherapy as palliative treatment in extrahepatic biliary tract cancer"],"prefix":"10.1016","volume":"14","author":[{"given":"Gian Carlo","family":"Mattiucci","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"Autorino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Tringali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Perri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Balducci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Deodato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Antonietta","family":"Gambacorta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanna","family":"Mantini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Tagliaferri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimiliano","family":"Mutignani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessio Giuseppe","family":"Morganti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brachy.2014.12.002_bib1","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/jso.2930460303","article-title":"Carcinoma of the extrahepatic bile ducts","volume":"46","author":"Chao","year":"1991","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.brachy.2014.12.002_bib2","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1002\/(SICI)1096-9098(199803)67:3<203::AID-JSO12>3.0.CO;2-2","article-title":"Biliary tree malignancies","volume":"67","author":"Erickson","year":"1998","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.brachy.2014.12.002_bib3","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s005350050355","article-title":"Diagnosis and non-surgical treatment of bile duct carcinoma developments in the past decade","volume":"35","author":"Tamada","year":"2000","journal-title":"J Gastroenterol"},{"key":"10.1016\/j.brachy.2014.12.002_bib4","first-page":"631","article-title":"Intraluminal brachytherapy and selfexpandable stents in nonresectable biliary malignancies\u2014the question of long-term palliation","volume":"48","author":"Bruha","year":"2001","journal-title":"Hepatogastroenterology"},{"key":"10.1016\/j.brachy.2014.12.002_bib5","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1148\/radiology.200.3.8756921","article-title":"Malignant biliary duct obstruction: Long-term experience with Gianturco stents and combined modality radiation therapy","volume":"200","author":"Eschelman","year":"1996","journal-title":"Radiology"},{"key":"10.1016\/j.brachy.2014.12.002_bib6","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/0360-3016(95)02132-9","article-title":"The role of radiotherapy in the management of extrahepatic bile duct cancer: An analyses of 145 consecutive patients treated with intraluminal and\/or external beam radiotherapy","volume":"34","author":"Kamada","year":"1996","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2014.12.002_bib7","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1097\/01.COC.0000026833.73428.1F","article-title":"Cholangiocarcinoma: The impact of tumor location and treatment strategy on outcome","volume":"26","author":"Heron","year":"2003","journal-title":"Am J Clin Oncol"},{"key":"10.1016\/j.brachy.2014.12.002_bib8","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1002\/1097-0142(19860201)57:3<536::AID-CNCR2820570322>3.0.CO;2-L","article-title":"Intraluminal radiation therapy in the management of malignant biliary obstruction","volume":"57","author":"Molt","year":"1986","journal-title":"Cancer"},{"key":"10.1016\/j.brachy.2014.12.002_bib9","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/0360-3016(90)90453-Q","article-title":"Combined modality therapy of extrahepatic biliary system cancer","volume":"18","author":"Minsky","year":"1990","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2014.12.002_bib10","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1148\/127.3.767","article-title":"Radiotherapy of carcinomas of the extrahepatic biliary system","volume":"127","author":"Pilepich","year":"1978","journal-title":"Radiology"},{"key":"10.1016\/j.brachy.2014.12.002_bib11","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1016\/S0360-3016(00)00792-6","article-title":"Interstitial high-dose-rate brachytherapy boost: The feasibility and cosmetic outcome of a fractionated outpatient delivery scheme","volume":"48","author":"Manning","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2014.12.002_bib12","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1055\/s-2007-1010295","article-title":"Plastic endoprothesis versus metal stents in the palliative treatment of malignant hilar biliary obstruction. A prospective and randomized trial","volume":"25","author":"Wagner","year":"1993","journal-title":"Endoscopy"},{"key":"10.1016\/j.brachy.2014.12.002_bib13","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1111\/j.1478-3231.2006.01439.x","article-title":"Endoscopic intraluminal brachytherapy and metal stent in malignant hilar biliary obstruction: A pilot study","volume":"27","author":"Singh","year":"2007","journal-title":"Liver Int"},{"key":"10.1016\/j.brachy.2014.12.002_bib14","first-page":"1567","article-title":"Clinical value of brachytherapy of malignant biliary obstruction after implanting expandable metallic biliary endoprothesis","volume":"23","author":"Zhang","year":"2004","journal-title":"Ai Zheng"},{"key":"10.1016\/j.brachy.2014.12.002_bib15","doi-asserted-by":"crossref","first-page":"3506","DOI":"10.3748\/wjg.v10.i23.3506","article-title":"HDR-192Ir intraluminal brachytherapy in treatment of malignant obstructive jaundice","volume":"10","author":"Chen","year":"2004","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.brachy.2014.12.002_bib16","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/0360-3016(94)90576-2","article-title":"Combined external radiotherapy and intraluminal high dose rate brachytherapy on bile duct carcinomas","volume":"29","author":"Frits","year":"1994","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2014.12.002_bib17","first-page":"200","article-title":"Intraluminal brachytherapy with metallic stenting in the palliative treatment of malignant obstruction of the bile duct","volume":"23","author":"Kocak","year":"2005","journal-title":"Radiat Med"}],"container-title":["Brachytherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538472114007089?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538472114007089?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T02:09:35Z","timestamp":1761530975000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1538472114007089"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["S1538472114007089"],"URL":"https:\/\/doi.org\/10.1016\/j.brachy.2014.12.002","relation":{},"ISSN":["1538-4721"],"issn-type":[{"value":"1538-4721","type":"print"}],"subject":[],"published":{"date-parts":[[2015,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Phase I study of high-dose-rate intraluminal brachytherapy as palliative treatment in extrahepatic biliary tract cancer","name":"articletitle","label":"Article Title"},{"value":"Brachytherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brachy.2014.12.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}