{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T05:02:24Z","timestamp":1761541344989,"version":"build-2065373602"},"reference-count":25,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["brachyjournal.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brachytherapy"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.brachy.2016.08.006","type":"journal-article","created":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T18:51:30Z","timestamp":1475347890000},"page":"832-838","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["The dosimetric impact of air in vaginal vault brachytherapy"],"prefix":"10.1016","volume":"15","author":[{"given":"\u00c1ine","family":"Maxwell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niluja","family":"Thiruthaneeswaran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4322-4517","authenticated-orcid":false,"given":"Gerry","family":"Lowe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Wills","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samadara","family":"Sripali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter J.","family":"Hoskin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.brachy.2016.08.006_bib1","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1158\/1055-9965.EPI-04-0871","article-title":"Endometrial cancer incidence trends in Europe: Underlying determinants and prospects for prevention","volume":"14","author":"Bray","year":"2005","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.brachy.2016.08.006_bib2","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1038\/bjc.2011.68","article-title":"Differential trends in the rising incidence of endometrial cancer by type: Data from a UK population-based registry from 1994 to 2006","volume":"104","author":"Evans","year":"2011","journal-title":"Br J Cancer"},{"key":"10.1016\/j.brachy.2016.08.006_bib3","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/j.1471-0528.2011.03201.x","article-title":"Cancer of the body of the uterus: Trends in mortality and incidence in England, 1985-2008","volume":"119","author":"Duncan","year":"2012","journal-title":"BJOG"},{"key":"10.1016\/j.brachy.2016.08.006_bib4","doi-asserted-by":"crossref","first-page":"e631","DOI":"10.1016\/j.ijrobp.2011.04.013","article-title":"Fifteen-year radiotherapy outcomes of the randomized PORTEC-1 trial for endometrial carcinoma","volume":"81","author":"Creutzberg","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2016.08.006_bib5","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/j.ygyno.2003.11.048","article-title":"A phase III trial of surgery with or without adjunctive external pelvic radiation therapy in intermediate risk endometrial adenocarcinoma: A Gynecologic Oncology Group study","volume":"92","author":"Keys","year":"2004","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.brachy.2016.08.006_bib6","first-page":"CD003916","article-title":"Adjuvant radiotherapy for stage I endometrial cancer","author":"Kong","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.brachy.2016.08.006_bib7","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/S0140-6736(09)62163-2","article-title":"Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): An open-label, non-inferiority, randomised trial","volume":"375","author":"Nout","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.brachy.2016.08.006_bib8","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.brachy.2005.02.002","article-title":"Vaginal lymphatic channel location and its implication for intracavitary brachytherapy radiation treatment","volume":"4","author":"Choo","year":"2005","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2016.08.006_bib9","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.brachy.2011.08.005","article-title":"American Brachytherapy Society consensus guidelines for adjuvant vaginal cuff brachytherapy after hysterectomy","volume":"11","author":"Small","year":"2012","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2016.08.006_bib10","unstructured":"Hoskin PJ, Nout R, Hellebust T, J\u00fcrgenliemk-Schulz I, van Limbergen E, Haie Meder C, Potter R. Endometrial cancer In: ESTRO Handbook of Brachytherapy, Second Edition. Available at: http:\/\/www.estro.org\/search?q=GEC-ESTRO+Handbook+endometrial+cancer&type=Guideline."},{"key":"10.1016\/j.brachy.2016.08.006_bib11","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1016\/j.ijrobp.2011.04.014","article-title":"External pelvic and vaginal irradiation versus vaginal irradiation alone as postoperative therapy in medium-risk endometrial carcinoma\u2013a prospective randomized study","volume":"82","author":"Sorbe","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2016.08.006_bib12","doi-asserted-by":"crossref","first-page":"135","DOI":"10.5114\/jcb.2012.30679","article-title":"Dosimetry and toxicity outcomes in postoperative high-dose-rate intracavitary brachytherapy for endometrial carcinoma","volume":"4","author":"Donnelly","year":"2012","journal-title":"J Contemp Brachytherapy"},{"key":"10.1016\/j.brachy.2016.08.006_bib13","doi-asserted-by":"crossref","first-page":"357","DOI":"10.5114\/jcb.2015.54952","article-title":"Bladder (ICRU) dose point does not predict urinary acute toxicity in adjuvant isolated vaginal vault high-dose-rate brachytherapy for intermediate-risk endometrial cancer","volume":"7","author":"Sapienza","year":"2015","journal-title":"J Contemp Brachytherapy"},{"key":"10.1016\/j.brachy.2016.08.006_bib14","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.brachy.2011.12.009","article-title":"Is there any advantage to three-dimensional planning for vaginal cuff brachytherapy?","volume":"11","author":"Kim","year":"2012","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2016.08.006_bib15","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.brachy.2008.07.004","article-title":"Brachytherapy in endometrial cancer: Quantification of air gaps around a vaginal cylinder","volume":"7","author":"Cameron","year":"2008","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2016.08.006_bib16","doi-asserted-by":"crossref","first-page":"20140694","DOI":"10.1259\/bjr.20140694","article-title":"The impact of air pockets around the vaginal cylinder on vaginal vault brachytherapy","volume":"88","author":"Onal","year":"2015","journal-title":"Br J Radiol"},{"key":"10.1016\/j.brachy.2016.08.006_bib17","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.ijrobp.2009.11.004","article-title":"Dosimetric effects of air pockets around high-dose rate brachytherapy vaginal cylinders","volume":"78","author":"Richardson","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2016.08.006_bib18","doi-asserted-by":"crossref","first-page":"271","DOI":"10.5114\/jcb.2014.45436","article-title":"Assessment of air pockets in high-dose-rate vaginal cuff brachytherapy using cylindrical applicators","volume":"6","author":"Hassouna","year":"2014","journal-title":"J Contemp Brachytherapy"},{"key":"10.1016\/j.brachy.2016.08.006_bib19","doi-asserted-by":"crossref","first-page":"20120428","DOI":"10.1259\/bjr.20120428","article-title":"Vaginal vault brachytherapy in endometrial cancer: Verifying target coverage with image-guided applicator placement","volume":"86","author":"Humphrey","year":"2013","journal-title":"Br J Radiol"},{"key":"10.1016\/j.brachy.2016.08.006_bib20","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1118\/1.597458","article-title":"Dosimetry of interstitial brachytherapy sources: Recommendations of the AAPM radiation therapy Committee Task Group No. 43. American Association of Physicists in Medicine","volume":"22","author":"Nath","year":"1995","journal-title":"Med Phys"},{"key":"10.1016\/j.brachy.2016.08.006_bib21","unstructured":"Ma Y. ALGEBRA2 [computer program: cited 2015 15 September]. Available at: https:\/\/bitbucket.org\/physmed\/algebra2\/overview."},{"key":"10.1016\/j.brachy.2016.08.006_bib22","doi-asserted-by":"crossref","first-page":"3273","DOI":"10.1088\/0031-9155\/57\/11\/3273","article-title":"ALGEBRA: ALgorithm for the heterogeneous dosimetry based on GEANT4 for BRAchytherapy","volume":"57","author":"Afsharpour","year":"2012","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.brachy.2016.08.006_bib23","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1093\/humrep\/del022","article-title":"Baseline dimensions of the human vagina","volume":"21","author":"Barnhart","year":"2006","journal-title":"Hum Reprod"},{"key":"10.1016\/j.brachy.2016.08.006_bib24","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.radonc.2015.06.016","article-title":"Can we shorten the overall treatment time in postoperative brachytherapy of endometrial carcinoma? Comparison of two brachytherapy schedules","volume":"116","author":"Rovirosa","year":"2015","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.brachy.2016.08.006_bib25","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1016\/j.ijrobp.2004.12.079","article-title":"Intravaginal high-dose-rate brachytherapy for stage I endometrial cancer: A randomized study of two dose-per-fraction levels","volume":"62","author":"Sorbe","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["Brachytherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538472116305359?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538472116305359?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T02:11:05Z","timestamp":1761531065000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1538472116305359"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["S1538472116305359"],"URL":"https:\/\/doi.org\/10.1016\/j.brachy.2016.08.006","relation":{},"ISSN":["1538-4721"],"issn-type":[{"type":"print","value":"1538-4721"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The dosimetric impact of air in vaginal vault brachytherapy","name":"articletitle","label":"Article Title"},{"value":"Brachytherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brachy.2016.08.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}