{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:51:16Z","timestamp":1786985476658,"version":"build-2736575974"},"reference-count":30,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["brachyjournal.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brachytherapy"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.brachy.2019.04.272","type":"journal-article","created":{"date-parts":[[2019,5,31]],"date-time":"2019-05-31T08:45:33Z","timestamp":1559292333000},"page":"620-626","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Detection of air gaps around the cylinder by postinsertion computed tomography in vaginal cuff brachytherapy: A prospective series, systematic review, and meta-analysis"],"prefix":"10.1016","volume":"18","author":[{"given":"Lucas Gomes","family":"Sapienza","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew Stephen","family":"Ning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ant\u00f4nio C\u00e1ssio de Assis","family":"Pellizzon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anuja","family":"Jhingran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann H.","family":"Klopp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilie L.","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marisa A.","family":"Kollmeier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vin\u00edcius Fernando","family":"Calsavara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naira dos Santos","family":"Gutierrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rubens","family":"Chojniak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Jos\u00e9 Leite","family":"Gomes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glauco","family":"Baiocchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brachy.2019.04.272_bib1","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/S0140-6736(09)62163-2","article-title":"Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): An open-label, non-inferiority, randomised trial","volume":"375","author":"Nout","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.brachy.2019.04.272_bib2","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1038\/s41416-018-0310-8","article-title":"Ten-year results of the PORTEC-2 trial for high-intermediate risk endometrial carcinoma: Improving patient selection for adjuvant therapy","volume":"119","author":"Wortman","year":"2018","journal-title":"Br J Cancer"},{"key":"10.1016\/j.brachy.2019.04.272_bib3","doi-asserted-by":"crossref","first-page":"e8384","DOI":"10.1097\/MD.0000000000008384","article-title":"Comparison of chemoradiotherapy with and without brachytherapy as adjuvant therapy after radical surgery in early-stage cervical cancer with poor prognostic factors: An observational study","volume":"96","author":"Lan","year":"2017","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.brachy.2019.04.272_bib4","doi-asserted-by":"crossref","first-page":"809","DOI":"10.2214\/ajr.135.4.809","article-title":"CT for intracavitary radiotherapy planning","volume":"135","author":"Lee","year":"1980","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.brachy.2019.04.272_bib5","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0167-8140(92)90372-2","article-title":"Dosimetry of intracavitary placements for uterine and cervical carcinoma: Results of orthogonal film, TLD, and CT-assisted techniques","volume":"24","author":"Kapp","year":"1992","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.brachy.2019.04.272_bib6","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.brachy.2008.07.004","article-title":"Brachytherapy in endometrial cancer: Quantification of air gaps around vaginal cylinder","volume":"7","author":"Cameron","year":"2008","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2019.04.272_bib7","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.brachy.2005.02.002","article-title":"Vaginal lymphatic channel location and its implication for intracavitary brachytherapy radiation treatment","volume":"4","author":"Choo","year":"2005","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2019.04.272_bib8","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.brachy.2011.08.005","article-title":"American Brachytherapy Society consensus guidelines for adjuvant vaginal cuff brachytherapy after hysterectomy","volume":"11","author":"Small","year":"2012","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2019.04.272_bib9","doi-asserted-by":"crossref","first-page":"e1000097","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred reporting items for systematic reviews and meta-analysis: The PRIMA statement","volume":"6","author":"Moher","year":"2009","journal-title":"PLoS Med"},{"key":"10.1016\/j.brachy.2019.04.272_bib10","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/S0140-6736(07)61602-X","article-title":"The strengthening the reporting of observational studies in epidemiology (STROBE) statement: Guidelines for reporting observational studies","volume":"370","author":"von Elm","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.brachy.2019.04.272_bib11","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1136\/jech-2013-203104","article-title":"Meta-analysis of prevalence","volume":"67","author":"Barendregt","year":"2013","journal-title":"J Epidemiol Community Health"},{"key":"10.1016\/j.brachy.2019.04.272_bib12","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1001\/jama.295.6.676","article-title":"Comparison of two methods to detect publication bias in meta-analysis","volume":"295","author":"Peters","year":"2006","journal-title":"JAMA"},{"key":"10.1016\/j.brachy.2019.04.272_bib13","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.ijrobp.2009.11.004","article-title":"Dosimetric effects of air pockets around high-dose rate brachytherapy vaginal cylinders","volume":"78","author":"Richardson","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2019.04.272_bib14","doi-asserted-by":"crossref","first-page":"20120428","DOI":"10.1259\/bjr.20120428","article-title":"Vaginal vault brachytherapy in endometrial cancer: Verifying target coverage with image-guided applicator placement","volume":"85","author":"Humphrey","year":"2013","journal-title":"Br J Radiol"},{"key":"10.1016\/j.brachy.2019.04.272_bib15","first-page":"S725","article-title":"Quantification of air gaps using CT in vaginal vault brachytherapy","volume":"49","author":"Zahra","year":"2013","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.brachy.2019.04.272_bib16","doi-asserted-by":"crossref","first-page":"271","DOI":"10.5114\/jcb.2014.45436","article-title":"Assessment of air pockets in high-dose-rate vaginal cuff brachytherapy using cylindrical applicators","volume":"6","author":"Hassouna","year":"2014","journal-title":"J Contemp Brachytherapy"},{"key":"10.1016\/j.brachy.2019.04.272_bib17","doi-asserted-by":"crossref","first-page":"20140694","DOI":"10.1259\/bjr.20140694","article-title":"The impact of air pockets around the vaginal cylinder on vaginal vault brachytherapy","volume":"88","author":"Onal","year":"2015","journal-title":"Br J Radiol"},{"key":"10.1016\/j.brachy.2019.04.272_bib18","doi-asserted-by":"crossref","first-page":"E271","DOI":"10.1016\/j.ijrobp.2015.07.1231","article-title":"Assessment of air cavities in high-dose-rate vaginal cuff brachytherapy using cylindrical and balloon-type applicators","volume":"93","author":"Jiang","year":"2015","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2019.04.272_bib19","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.brachy.2016.08.006","article-title":"The dosimetric impact of air in vaginal vault brachytherapy","volume":"15","author":"Maxwell","year":"2016","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2019.04.272_bib20","doi-asserted-by":"crossref","first-page":"S978","DOI":"10.1016\/S0167-8140(17)32143-6","article-title":"EP-1781: Statistical and dosimetric analysis of air gaps in vaginal cuff brachytherapy","volume":"123","author":"Abdollahi","year":"2017","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.brachy.2019.04.272_bib21","doi-asserted-by":"crossref","first-page":"28074","DOI":"10.1038\/srep28074","article-title":"Volumetric (3D) bladder dose parameters are more reproducible than point (2D) dose parameters in vaginal vault high-dose-rate brachytherapy","volume":"6","author":"Sapienza","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.brachy.2019.04.272_bib22","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.ijrobp.2008.01.041","article-title":"Prospective clinical trial of bladder filling and three-dimensional dosimetry in high-dose-rate vaginal cuff brachytherapy","volume":"72","author":"Stewart","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2019.04.272_bib23","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.prro.2012.10.002","article-title":"Dosimetric and cost comparison of first fraction imaging versus fractional re-imaging on critical organ dose in vaginal cuff brachytherapy","volume":"3","author":"Corso","year":"2013","journal-title":"Pract Radiat Oncol"},{"key":"10.1016\/j.brachy.2019.04.272_bib24","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1259\/bjr.75.891.750234","article-title":"The influence of applicator angle on dosimetry in vaginal vault brachytherapy","volume":"75","author":"Hoskin","year":"2002","journal-title":"Br J Radiol"},{"key":"10.1016\/j.brachy.2019.04.272_bib25","doi-asserted-by":"crossref","first-page":"e75","DOI":"10.1016\/j.ijrobp.2011.11.029","article-title":"Comparison of 2D and 3D imaging and treatment planning for postoperative vaginal apex high-dose rate brachytherapy for endometrial cancer","volume":"83","author":"Russo","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2019.04.272_bib26","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1016\/j.ijrobp.2011.08.023","article-title":"Image-based 3D treatment planning for vaginal cylinder brachytherapy: Dosimetric effects of bladder filling on organ at risk","volume":"83","author":"Hung","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2019.04.272_bib27","doi-asserted-by":"crossref","first-page":"357","DOI":"10.5114\/jcb.2015.54952","article-title":"Bladder (ICRU) dose point does not predict urinary acute toxicity in adjuvant isolated vaginal vault high-dose-rate brachytherapy for intermediate-risk endometrial cancer","volume":"7","author":"Sapienza","year":"2015","journal-title":"J Contemp Brachytherapy"},{"key":"10.1016\/j.brachy.2019.04.272_bib28","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.brachy.2015.02.391","article-title":"Dosimetric analysis of rectal filling on rectal doses during vaginal cuff brachytherapy","volume":"14","author":"Sabater","year":"2015","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2019.04.272_bib29","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.brachy.2007.03.005","article-title":"An analysis of simulation for adjuvant intracavitary high-dose-rate brachytherapy in early-stage endometrial cancer","volume":"6","author":"Barney","year":"2007","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2019.04.272_bib30","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.brachy.2013.09.007","article-title":"Evaluating adjacent organ radiation doses from postoperative intracavitary vaginal vault brachytherapy for endometrial cancer","volume":"13","author":"Caon","year":"2014","journal-title":"Brachytherapy"}],"container-title":["Brachytherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S153847211930025X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S153847211930025X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T02:15:07Z","timestamp":1761531307000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S153847211930025X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["S153847211930025X"],"URL":"https:\/\/doi.org\/10.1016\/j.brachy.2019.04.272","relation":{},"ISSN":["1538-4721"],"issn-type":[{"value":"1538-4721","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Detection of air gaps around the cylinder by postinsertion computed tomography in vaginal cuff brachytherapy: A prospective series, systematic review, and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Brachytherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brachy.2019.04.272","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}