{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T06:20:03Z","timestamp":1778826003540,"version":"3.51.4"},"reference-count":31,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100007210","name":"Varian Medical Systems","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007210","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["brachyjournal.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brachytherapy"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.brachy.2019.05.009","type":"journal-article","created":{"date-parts":[[2019,6,24]],"date-time":"2019-06-24T17:43:44Z","timestamp":1561398224000},"page":"675-682","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["A surrogate urethra for real-time planning of high-dose-rate prostate brachytherapy"],"prefix":"10.1016","volume":"18","author":[{"given":"Heather","family":"Halperin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Hilts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juanita","family":"Crook","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deidre","family":"Batchelar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Tisseverasinghe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Audrey","family":"Tetreault-LaFlamme","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francois","family":"Bachand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.brachy.2019.05.009_bib1","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.brachy.2011.09.008","article-title":"American Brachytherapy Society consensus guidelines for high-dose-rate","volume":"11","author":"Yamada","year":"2012","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2019.05.009_bib2","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.brachy.2011.07.009","article-title":"Urethra low-dose tunnels: validation of and class solution for generating urethra-sparing dose plans using inverse planning simulated annealing for prostate high-dose-rate brachytherapy","volume":"11","author":"Cunha","year":"2012","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2019.05.009_bib3","doi-asserted-by":"crossref","first-page":"51","DOI":"10.5489\/cuaj.218","article-title":"Canadian prostate brachytherapy in 2012","volume":"7","author":"Keyes","year":"2013","journal-title":"Can Urol Assoc J"},{"key":"10.1016\/j.brachy.2019.05.009_bib4","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1016\/j.ijrobp.2005.10.005","article-title":"Anatomy-based inverse optimization in high-dose-rate brachytherapy combined with hypofractionated external beam radiotherapy for localized prostate cancer","volume":"64","author":"Akimoto","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2019.05.009_bib5","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1017\/S1460396913000265","article-title":"Treatment planning comparison between high dose rate and intensity-modulated radiation therapy for prostate cancer as a means of boost dose","volume":"13","author":"Bose","year":"2014","journal-title":"J Radiother Pract"},{"key":"10.1016\/j.brachy.2019.05.009_bib6","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.ijrobp.2008.11.006","article-title":"Genitourinary toxicity after high-dose-rate (HDR) brachytherapy combined with hypofractionated external beam radiotherapy for localized prostate cancer","volume":"75","author":"Ishiyama","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2019.05.009_bib7","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S1538-4721(02)00101-0","article-title":"LDR vs. HDR brachytherapy for localized prostate cancer: the view from radiobiological models","volume":"1","author":"King","year":"2002","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2019.05.009_bib8","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1016\/j.ijrobp.2004.02.055","article-title":"Inverse planning for HDR prostate brachytherapy used to boost dominant intraprostatic lesions defined by magnetic resonance spectroscopy imaging","volume":"59","author":"Pouliot","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2019.05.009_bib9","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.brachy.2014.05.006","article-title":"Ultrasound-planned high-dose-rate prostate brachytherapy: dose painting to the dominant intraprostatic lesion","volume":"13","author":"Crook","year":"2014","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2019.05.009_bib10","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.brachy.2016.11.005","article-title":"Results of multiparametric transrectal ultrasound-based focal high-dose-rate dose escalation combined with supplementary external beam irradiation in intermediate- and high-risk localized prostate cancer patients","volume":"16","author":"Kov\u00e1cs","year":"2017","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2019.05.009_bib11","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1038\/nrurol.2017.76","article-title":"The evolution of brachytherapy for prostate cancer","volume":"14","author":"Zaorsky","year":"2017","journal-title":"Nat Rev Urol"},{"key":"10.1016\/j.brachy.2019.05.009_bib12","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1016\/j.ijrobp.2004.08.014","article-title":"High-dose-rate intensity-modulated brachytherapy with external beam radiotherapy for prostate cancer: California endocurie therapy\u2019s 10-year results","volume":"61","author":"Demanes","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2019.05.009_bib13","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.prro.2013.02.011","article-title":"Dosimetric analysis of radiation therapy oncology group 0321: the importance of urethral dose","volume":"4","author":"Hsu","year":"2014","journal-title":"Pract Radiat Oncol"},{"key":"10.1016\/j.brachy.2019.05.009_bib14","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.ijrobp.2004.11.041","volume":"63","author":"Akimoto","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2019.05.009_bib15","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.ijrobp.2005.02.015","article-title":"Genitourinary toxicity after high dose rate (HDR) brachytherapy combined with hypofractionated external-beam radiation therapy for localized prostate cancer: second analysis to determine the correlation between the urethral dose in HDR brachytherapy","volume":"63","author":"Akimoto","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2019.05.009_bib16","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1046\/j.1440-1673.2002.01091.x","article-title":"Dose distribution and morbidity after high dose rate brachytherapy for prostate cancer: influence of V150 and V200 parameters","volume":"46","author":"Duchesne","year":"2002","journal-title":"Australas Radiol"},{"key":"10.1016\/j.brachy.2019.05.009_bib17","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.radonc.2013.05.002","article-title":"GEC\/ESTRO recommendations on high dose rate afterloading brachytherapy for localised prostate cancer: an update","volume":"107","author":"Hoskin","year":"2013","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.brachy.2019.05.009_bib18","series-title":"Basic and advanced techniques in prostate brachytherapy","author":"Dicker","year":"2005"},{"key":"10.1016\/j.brachy.2019.05.009_bib19","first-page":"251","article-title":"Function of seminal vesicles and their role on male fertility","volume":"3","author":"Gonzales","year":"2001","journal-title":"Asian J Androl"},{"key":"10.1016\/j.brachy.2019.05.009_bib20","doi-asserted-by":"crossref","first-page":"728539","DOI":"10.1155\/2014\/728539","article-title":"Anatomic imaging of the prostate","volume":"2014","author":"Bhavsar","year":"2014","journal-title":"Biomed Res Int"},{"key":"10.1016\/j.brachy.2019.05.009_bib21","doi-asserted-by":"crossref","first-page":"53","DOI":"10.2307\/2981392","article-title":"The elementary statistics of majority voting","volume":"1","author":"Penrose","year":"1946","journal-title":"J R Stat Soc"},{"key":"10.1016\/j.brachy.2019.05.009_bib22","doi-asserted-by":"crossref","first-page":"297","DOI":"10.2307\/1932409","article-title":"Measures of the amount of ecologic association between species","volume":"26","author":"Dice","year":"1945","journal-title":"Ecology"},{"key":"10.1016\/j.brachy.2019.05.009_bib23","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1007\/s00066-011-0027-6","article-title":"Critical discussion of evaluation parameters for inter-observer variability in target definition for radiation therapy","volume":"188","author":"Fotina","year":"2012","journal-title":"Strahlenther Onkol"},{"key":"10.1016\/j.brachy.2019.05.009_bib24","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1259\/bjr.20140732","article-title":"Evaluation and optimization of the parameters used in multiple-atlas-based segmentation of prostate cancers in radiation therapy","volume":"89","author":"Wong","year":"2016","journal-title":"Br J Radiol"},{"key":"10.1016\/j.brachy.2019.05.009_bib25","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.neuroimage.2017.03.010","article-title":"Spinal cord grey matter segmentation challenge","volume":"152","author":"Prados","year":"2017","journal-title":"Neuroimage"},{"key":"10.1016\/j.brachy.2019.05.009_bib26","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1136\/bmj.308.6943.1552","article-title":"Diagnostic tests 1: sensitivity and specificity","volume":"308","author":"Altman","year":"1994","journal-title":"BMJ"},{"key":"10.1016\/j.brachy.2019.05.009_bib27","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1214\/aoms\/1177729885","article-title":"Sample criteria for testing outlying observations","volume":"21","author":"Grubbs","year":"1950","journal-title":"Ann Math Stat"},{"key":"10.1016\/j.brachy.2019.05.009_bib28","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1016\/S0360-3016(02)03054-7","article-title":"Urethral and periurethral dosimetry in prostate brachytherapy: is there a convenient surrogate?","volume":"15","author":"Bucci","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2019.05.009_bib29","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.clon.2016.04.041","article-title":"Acute and late genitourinary toxicity after 72 Gy of conventionally fractionated conformal radiotherapy for localized prostate cancer: impact of individual and clinical parameters","volume":"28","author":"Stankovic","year":"2016","journal-title":"Clin Oncol"},{"key":"10.1016\/j.brachy.2019.05.009_bib30","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.brachy.2017.10.015","article-title":"Dosimetric impact of inter-observer catheter reconstruction variability in ultrasound-based high-dose-rate prostate brachytherapy","volume":"17","author":"Nicolae","year":"2017","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2019.05.009_bib31","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.radonc.2009.11.003","article-title":"I-125 seed planning: an alternative method of urethra definition","volume":"94","author":"Anderson","year":"2010","journal-title":"Radiother Oncol"}],"container-title":["Brachytherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S153847211930100X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S153847211930100X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T02:15:04Z","timestamp":1761531304000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S153847211930100X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["S153847211930100X"],"URL":"https:\/\/doi.org\/10.1016\/j.brachy.2019.05.009","relation":{},"ISSN":["1538-4721"],"issn-type":[{"value":"1538-4721","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A surrogate urethra for real-time planning of high-dose-rate prostate brachytherapy","name":"articletitle","label":"Article Title"},{"value":"Brachytherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brachy.2019.05.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown Copyright \u00a9 2019 Published by Elsevier Inc. on behalf of American Brachytherapy Society. All rights reserved.","name":"copyright","label":"Copyright"}]}}