{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T13:18:48Z","timestamp":1788268728703,"version":"build-2803163510"},"reference-count":37,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,6,11]],"date-time":"2020-06-11T00:00:00Z","timestamp":1591833600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["brachyjournal.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brachytherapy"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.brachy.2020.06.002","type":"journal-article","created":{"date-parts":[[2020,7,7]],"date-time":"2020-07-07T17:49:40Z","timestamp":1594144180000},"page":"635-641","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Adjuvant electronic brachytherapy for endometrial carcinoma: A 4-year outcomes report"],"prefix":"10.1016","volume":"19","author":[{"given":"Gustavo R.","family":"Sarria","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Sperk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6037-0853","authenticated-orcid":false,"given":"Frederik","family":"Wenz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2205-503X","authenticated-orcid":false,"given":"Yasser","family":"Abo-Madyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank A.","family":"Giordano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Ehmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brachy.2020.06.002_bib1","doi-asserted-by":"crossref","first-page":"581","DOI":"10.5114\/jcb.2017.72607","article-title":"Current status of brachytherapy in cancer treatment - short overview","volume":"9","author":"Skowronek","year":"2017","journal-title":"J Contemp Brachytherapy"},{"key":"10.1016\/j.brachy.2020.06.002_bib2","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.ijrobp.2013.05.033","article-title":"Trends in the utilization of brachytherapy in cervical cancer in the United States","volume":"87","author":"Han","year":"2013","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2020.06.002_bib3","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.ijrobp.2013.11.011","article-title":"Curative radiation therapy for locally advanced cervical cancer: brachytherapy is NOT optional","volume":"88","author":"Tanderup","year":"2014","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2020.06.002_bib4","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.ijrobp.2017.09.004","article-title":"Evaluation of delivery costs for external beam radiation therapy and brachytherapy for locally advanced cervical cancer using time-driven activity-based costing","volume":"100","author":"Bauer-Nilsen","year":"2018","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2020.06.002_bib5","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.brachy.2018.12.002","article-title":"Understanding the underutilization of cervical brachytherapy for locally advanced cervical cancer","volume":"18","author":"Ma","year":"2019","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2020.06.002_bib6","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1016\/j.brachy.2017.04.235","article-title":"A national survey of HDR source knowledge among practicing radiation oncologists and residents: Establishing a willingness-to-pay threshold for cobalt-60 usage","volume":"16","author":"Mailhot Vega","year":"2017","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2020.06.002_bib7","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.brachy.2014.11.004","article-title":"Current state of brachytherapy teaching in Canada: A national survey of radiation oncologists, residents, and fellows","volume":"14","author":"Gaudet","year":"2015","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2020.06.002_bib8","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.brachy.2015.09.012","article-title":"Vaginal brachytherapy for postoperative endometrial cancer: 2014 Survey of the American Brachytherapy Society","volume":"15","author":"Harkenrider","year":"2016","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2020.06.002_bib9","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.brachy.2016.06.012","article-title":"Trends in the utilization of adjuvant vaginal brachytherapy in women with early-stage endometrial carcinoma: Results of an updated period analysis of SEER data","volume":"15","author":"Modh","year":"2016","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2020.06.002_bib10","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.ijrobp.2011.05.052","article-title":"Trends in the utilization of adjuvant vaginal cuff brachytherapy and\/or external beam radiation treatment in stage I and II endometrial cancer: A surveillance, epidemiology, and end-results study","volume":"83","author":"Patel","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2020.06.002_bib11","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1038\/s41416-018-0310-8","article-title":"Ten-year results of the PORTEC-2 trial for high-intermediate risk endometrial carcinoma: Improving patient selection for adjuvant therapy","volume":"119","author":"Wortman","year":"2018","journal-title":"Br J Cancer"},{"key":"10.1016\/j.brachy.2020.06.002_bib12","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.ijrobp.2015.08.023","article-title":"Long-term impact of endometrial cancer diagnosis and treatment on health-related quality of life and cancer survivorship: Results from the randomized PORTEC-2 trial","volume":"93","author":"de Boer","year":"2015","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2020.06.002_bib13","doi-asserted-by":"crossref","first-page":"503","DOI":"10.5114\/jcb.2018.79928","article-title":"Cost in perspective: Direct assessment of American market acceptability of Co-60 in gynecologic high-dose-rate brachytherapy and contrast with experience abroad","volume":"10","author":"Mailhot Vega","year":"2018","journal-title":"J Contemp Brachytherapy"},{"key":"10.1016\/j.brachy.2020.06.002_bib14","doi-asserted-by":"crossref","first-page":"S37","DOI":"10.1016\/j.brachy.2015.02.250","article-title":"Cost-benefit analysis of Co-60 HDR after loaders in management of gynecological malignancies: What constitutes an acceptable shielding cost?","volume":"14","author":"Vega","year":"2015","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2020.06.002_bib15","doi-asserted-by":"crossref","first-page":"20150002","DOI":"10.1259\/bjr.20150002","article-title":"Electronic brachytherapy\u2013current status and future directions","volume":"88","author":"Eaton","year":"2015","journal-title":"Br J Radiol"},{"key":"10.1016\/j.brachy.2020.06.002_bib16","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/j.ijrobp.2012.08.005","article-title":"Relative Biologic Effectiveness (RBE) of 50 kV X-rays measured in a phantom for intraoperative tumor-bed irradiation","volume":"85","author":"Liu","year":"2013","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2020.06.002_bib18","series-title":"AJCC Cancer Staging Handbook","first-page":"403","author":"Edge","year":"2010"},{"key":"10.1016\/j.brachy.2020.06.002_bib19","doi-asserted-by":"crossref","first-page":"197","DOI":"10.2147\/OTT.S13593","article-title":"Use of electronic brachytherapy to deliver postsurgical adjuvant radiation therapy for endometrial cancer: a retrospective multicenter study","volume":"3","author":"Dooley","year":"2010","journal-title":"OncoTargets Ther"},{"key":"10.1016\/j.brachy.2020.06.002_bib20","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.brachy.2012.04.003","article-title":"Electronic brachytherapy for postsurgical adjuvant vaginal cuff irradiation therapy in endometrial and cervical cancer: a retrospective study","volume":"12","author":"Kamrava","year":"2013","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2020.06.002_bib21","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/1748-717X-5-67","article-title":"Prospective multi-center trial utilizing electronic brachytherapy for the treatment of endometrial cancer","volume":"5","author":"Dickler","year":"2010","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.brachy.2020.06.002_bib22","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.brachy.2018.10.006","article-title":"The American Brachytherapy Society consensus statement for electronic brachytherapy","volume":"18","author":"Tom","year":"2019","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2020.06.002_bib23","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1016\/j.ijrobp.2009.01.082","article-title":"A novel device for intravaginal electronic brachytherapy","volume":"74","author":"Schneider","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2020.06.002_bib24","doi-asserted-by":"crossref","first-page":"20150449","DOI":"10.1259\/bjr.20150449","article-title":"Dosimetric comparison of brachytherapy sources for high-dose-rate treatment of endometrial cancer: (192)Ir, (60)Co and an electronic brachytherapy source","volume":"89","author":"Mobit","year":"2016","journal-title":"Br J Radiol"},{"key":"10.1016\/j.brachy.2020.06.002_bib25","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.brachy.2008.05.003","article-title":"A dosimetric comparison of Xoft Axxent Electronic Brachytherapy and iridium-192 high-dose-rate brachytherapy in the treatment of endometrial cancer","volume":"7","author":"Dickler","year":"2008","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2020.06.002_bib26","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.brachy.2011.08.004","article-title":"A comparison of the biological effective dose of 50-kV electronic brachytherapy with (192)Ir high-dose-rate brachytherapy for vaginal cuff irradiation","volume":"11","author":"Rava","year":"2012","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2020.06.002_bib27","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.brachy.2011.08.005","article-title":"American Brachytherapy Society consensus guidelines for adjuvant vaginal cuff brachytherapy after hysterectomy","volume":"11","author":"Small","year":"2012","journal-title":"Brachytherapy"},{"key":"10.1016\/j.brachy.2020.06.002_bib28","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1016\/j.ijrobp.2004.12.079","article-title":"Intravaginal high-dose-rate brachytherapy for stage I endometrial cancer: A randomized study of two dose-per-fraction levels","volume":"62","author":"Sorbe","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2020.06.002_bib29","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1016\/j.ijrobp.2011.04.014","article-title":"External pelvic and vaginal irradiation versus vaginal irradiation alone as postoperative therapy in medium-risk endometrial carcinoma\u2013a prospective randomized study","volume":"82","author":"Sorbe","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2020.06.002_bib30","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/S0140-6736(09)62163-2","article-title":"Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): An open-label, non-inferiority, randomised trial","volume":"375","author":"Nout","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.brachy.2020.06.002_bib31","doi-asserted-by":"crossref","first-page":"559","DOI":"10.5114\/jcb.2018.79713","article-title":"Vaginal toxicity after high-dose-rate endovaginal brachytherapy: 20 years of results","volume":"10","author":"Delishaj","year":"2018","journal-title":"J Contemp Brachytherapy"},{"key":"10.1016\/j.brachy.2020.06.002_bib32","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.ijrobp.2006.09.004","article-title":"Comparison of high-dose-rate and low-dose-rate brachytherapy in the treatment of endometrial carcinoma","volume":"67","author":"Fayed","year":"2007","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2020.06.002_bib33","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1007\/s000660050039","article-title":"Die postoperative Strahlentherapie beim Endometriumkarzinom Eine retrospektive Analyse von 541 Patienten","volume":"175","author":"H\u00e4nsgen","year":"1999","journal-title":"Strahlenther Onkol"},{"key":"10.1016\/j.brachy.2020.06.002_bib34","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1007\/s12094-015-1463-z","article-title":"Vaginal-cuff control and toxicity results of a daily HDR brachytherapy schedule in endometrial cancer patients","volume":"18","author":"Rios","year":"2016","journal-title":"Clin Transl Oncol"},{"key":"10.1016\/j.brachy.2020.06.002_bib35","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/S0360-3016(98)00292-2","article-title":"High-dose-rate brachytherapy alone post-hysterectomy for endometrial cancer","volume":"42","author":"MacLeod","year":"1998","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2020.06.002_bib36","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/S0360-3016(00)01464-4","article-title":"Late reactions after postoperative high-dose-rate intravaginal brachytherapy for endometrial cancer: a comparison of standardized and individualized target volumes","volume":"49","author":"Onsrud","year":"2001","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.brachy.2020.06.002_bib37","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1097\/IGC.0b013e3182481611","article-title":"Sexual function after intracavitary vaginal brachytherapy for early-stage endometrial carcinoma","volume":"22","author":"Quick","year":"2012","journal-title":"Int J Gynecol Cancer"},{"key":"10.1016\/j.brachy.2020.06.002_bib38","doi-asserted-by":"crossref","first-page":"3547","DOI":"10.1200\/JCO.2008.20.2424","article-title":"Quality of life after pelvic radiotherapy or vaginal brachytherapy for endometrial cancer: first results of the randomized PORTEC-2 trial","volume":"27","author":"Nout","year":"2009","journal-title":"J Clin Oncol"}],"container-title":["Brachytherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538472120301203?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538472120301203?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T02:15:50Z","timestamp":1761531350000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1538472120301203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":37,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["S1538472120301203"],"URL":"https:\/\/doi.org\/10.1016\/j.brachy.2020.06.002","relation":{},"ISSN":["1538-4721"],"issn-type":[{"value":"1538-4721","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adjuvant electronic brachytherapy for endometrial carcinoma: A 4-year outcomes report","name":"articletitle","label":"Article Title"},{"value":"Brachytherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brachy.2020.06.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier Inc. on behalf of American Brachytherapy Society.","name":"copyright","label":"Copyright"}]}}