{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T20:11:35Z","timestamp":1784232695733,"version":"3.55.0"},"reference-count":17,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["brachyjournal.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brachytherapy"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.brachy.2022.06.004","type":"journal-article","created":{"date-parts":[[2022,8,13]],"date-time":"2022-08-13T07:32:54Z","timestamp":1660375974000},"page":"764-768","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Radical trachelectomy and adjuvant vaginal brachytherapy to preserve fertility in pediatric cervical adenocarcinoma"],"prefix":"10.1016","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1789-0391","authenticated-orcid":false,"given":"Ryan J.","family":"Hutten","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3931-3314","authenticated-orcid":false,"given":"Jordan B.","family":"Fenlon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8455-2018","authenticated-orcid":false,"given":"Adam C.","family":"Kessel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krystal M.","family":"Straessler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y. Jessica","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David K.","family":"Gaffney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gita","family":"Suneja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Zempolich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsay M.","family":"Burt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.brachy.2022.06.004_bib0001","doi-asserted-by":"crossref","first-page":"e191","DOI":"10.1016\/S2214-109X(19)30482-6","article-title":"Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis","volume":"8","author":"Arbyn","year":"2020","journal-title":"Lancet Glob Health"},{"key":"10.1016\/j.brachy.2022.06.004_bib0002","doi-asserted-by":"crossref","first-page":"e18646","DOI":"10.1097\/MD.0000000000018646","article-title":"Fertility-preserving local excision under a hysteroscope with combined chemotherapy in a 6-year-old child with clear cell adenocarcinoma of the cervix: a case report and review of the literature","volume":"99","author":"Su","year":"2020","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.brachy.2022.06.004_bib0003","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1159\/000356685","article-title":"Successful treatment of a young patient with locally advanced clear cell adenocarcinoma of the uterine cervix undergoing chemoradiation followed by radical surgery","volume":"77","author":"Ferrandina","year":"2014","journal-title":"Gynecol Obstet Invest"},{"key":"10.1016\/j.brachy.2022.06.004_bib0004","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1006\/gyno.1999.5700","article-title":"Clear cell carcinoma of the uterine cervix: pathology and prognosis in surgically treated stage IB-IIB disease in women not exposed in utero to diethylstilbestrol","volume":"76","author":"Reich","year":"2000","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.brachy.2022.06.004_bib0005","doi-asserted-by":"crossref","first-page":"111","DOI":"10.2147\/OTT.S53204","article-title":"Clear cell carcinoma of the uterine cervix: clinical characteristics and feasibility of fertility-preserving treatment","volume":"7","author":"Jiang","year":"2014","journal-title":"Onco Targets Ther"},{"key":"10.1016\/j.brachy.2022.06.004_bib0006","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/S0002-9440(10)64619-6","article-title":"Prevalence of human papillomavirus DNA in different histological subtypes of cervical adenocarcinoma","volume":"157","author":"Pirog","year":"2000","journal-title":"Am J Pathol"},{"key":"10.1016\/j.brachy.2022.06.004_bib0007","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.ygyno.2011.05.010","article-title":"Neoadjuvant chemotherapy and vaginal radical trachelectomy for fertility-sparing treatment in women affected by cervical cancer (FIGO stage IB-IIA1)","volume":"122","author":"Marchiole","year":"2011","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.brachy.2022.06.004_bib0008","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/j.ygyno.2006.05.044","article-title":"Fertility-sparing radical abdominal trachelectomy for cervical carcinoma: technique and review of the literature","volume":"103","author":"Abu-Rustum","year":"2006","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.brachy.2022.06.004_bib0009","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1006\/gyno.1999.5387","article-title":"A randomized trial of pelvic radiation therapy versus no further therapy in selected patients with stage IB carcinoma of the cervix after radical hysterectomy and pelvic lymphadenectomy: a Gynecologic Oncology Group Study","volume":"73","author":"Sedlis","year":"1999","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.brachy.2022.06.004_bib0010","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1200\/JCO.2000.18.8.1606","article-title":"Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix","volume":"18","author":"Peters","year":"2000","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.brachy.2022.06.004_bib0011","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.ygyno.2004.05.032","article-title":"Vaginal radical trachelectomy: an oncologically safe fertility-preserving surgery. An updated series of 72 cases and review of the literature","volume":"94","author":"M-CR","year":"2004","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.brachy.2022.06.004_bib0012","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.ygyno.2008.07.014","article-title":"Oncologic outcome of fertility-sparing radical trachelectomy versus radical hysterectomy for stage IB1 cervical carcinoma","volume":"111","author":"Diaz","year":"2008","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.brachy.2022.06.004_bib0013","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1016\/j.jpedsurg.2011.05.003","article-title":"Vaginal tumors in childhood: the experience of St. Jude Children's Research Hospital","volume":"46","author":"Fernandez-Pineda","year":"2011","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.brachy.2022.06.004_bib0014","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/pbc.20113","article-title":"Adenocarcinoma of the cervix and vagina in pediatric patients","volume":"43","author":"McNall","year":"2004","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.brachy.2022.06.004_bib0015","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/9465375","article-title":"Primary clear cell adenocarcinoma of the cervix: a clinical analysis of 18 cases without exposure to diethylstilbestrol","volume":"2019","author":"Wang","year":"2019","journal-title":"Obstet Gynecol Int"},{"key":"10.1016\/j.brachy.2022.06.004_bib0016","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1038\/s41416-018-0310-8","article-title":"Ten-year results of the PORTEC-2 trial for high-intermediate risk endometrial carcinoma: improving patient selection for adjuvant therapy","volume":"119","author":"Wortman","year":"2018","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.brachy.2022.06.004_bib0017","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1016\/j.ijrobp.2008.12.016","article-title":"Impact of radiotherapy on fertility, pregnancy, and neonatal outcomes in female cancer patients","volume":"73","author":"Wo","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["Brachytherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538472122001106?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1538472122001106?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T02:17:58Z","timestamp":1761531478000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1538472122001106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["S1538472122001106"],"URL":"https:\/\/doi.org\/10.1016\/j.brachy.2022.06.004","relation":{},"ISSN":["1538-4721"],"issn-type":[{"value":"1538-4721","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Radical trachelectomy and adjuvant vaginal brachytherapy to preserve fertility in pediatric cervical adenocarcinoma","name":"articletitle","label":"Article Title"},{"value":"Brachytherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.brachy.2022.06.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}