{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:00:50Z","timestamp":1791043250521,"version":"4.1.0"},"reference-count":10,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain and Development"],"published-print":{"date-parts":[[2012,10]]},"DOI":"10.1016\/j.braindev.2011.12.010","type":"journal-article","created":{"date-parts":[[2012,1,24]],"date-time":"2012-01-24T14:54:47Z","timestamp":1327416887000},"page":"776-779","source":"Crossref","is-referenced-by-count":13,"title":["Novel AGTR2 missense mutation in a Japanese boy with severe mental retardation, pervasive developmental disorder, and epilepsy"],"prefix":"10.1016","volume":"34","author":[{"given":"Eri","family":"Takeshita","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiji","family":"Nakagawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsutoshi","family":"Nakatani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-ichi","family":"Goto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.braindev.2011.12.010_b0005","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1038\/ng.367","article-title":"A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation","volume":"41","author":"Tarpey","year":"2009","journal-title":"Nat Genet"},{"key":"10.1016\/j.braindev.2011.12.010_b0010","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1126\/science.1072191","article-title":"AGTR2 mutations in X-linked mental retardation","volume":"296","author":"Vervoort","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.braindev.2011.12.010_b0015","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1136\/jmg.40.5.357","article-title":"Rare polymorphic variants of the AGTR2 gene in boys with non-specific mental retardation","volume":"40","author":"Bienvenu","year":"2003","journal-title":"J Med Genet"},{"key":"10.1016\/j.braindev.2011.12.010_b0020","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s00439-003-1048-8","article-title":"Identification of two AGTR2 mutations in male patients with non-syndromic mental retardation","volume":"114","author":"Ylisaukko-oja","year":"2004","journal-title":"Hum Genet"},{"key":"10.1016\/j.braindev.2011.12.010_b0025","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1038\/377748a0","article-title":"Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor","volume":"377","author":"Ichiki","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.braindev.2011.12.010_b0030","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1007\/s00109-008-0316-4","article-title":"Impaired spatial memory and altered dendritic spine morphology in angiotensin II type 2 receptor-deficient mice","volume":"86","author":"Maul","year":"2008","journal-title":"J Mol Med"},{"key":"10.1016\/j.braindev.2011.12.010_b0035","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1007\/s00439-003-1076-4","article-title":"The assertion that a G21V mutation in AGTR2 causes mental retardation is not supported by other studies","volume":"114","author":"Erdmann","year":"2004","journal-title":"Hum Genet"},{"key":"10.1016\/j.braindev.2011.12.010_b0040","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1002\/ajmg.a.31022","article-title":"Sequence variations in AGTR2 are unlikely to be associated with X-linked mental retardation","volume":"139","author":"Huang","year":"2005","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.braindev.2011.12.010_b0045","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1006\/bbrc.1999.1405","article-title":"Role of Arg182 in the second extracellular loop of angiotensin II receptor AT2 in ligand binding","volume":"263","author":"Kurfis","year":"1999","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.braindev.2011.12.010_b0050","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s00246-003-0662-5","article-title":"Polymorphism of angiotensin-1 converting enzyme gene and Kawasaki disease","volume":"25","author":"Wu","year":"2004","journal-title":"Pediatr Cardiol"}],"container-title":["Brain and Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0387760411003688?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0387760411003688?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,12,26]],"date-time":"2021-12-26T21:18:34Z","timestamp":1640553514000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0387760411003688"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":10,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["S0387760411003688"],"URL":"https:\/\/doi.org\/10.1016\/j.braindev.2011.12.010","relation":{},"ISSN":["0387-7604"],"issn-type":[{"value":"0387-7604","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10]]}}}