{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T04:18:26Z","timestamp":1790396306373,"version":"4.1.0"},"reference-count":10,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain and Development"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1016\/j.braindev.2012.12.001","type":"journal-article","created":{"date-parts":[[2012,12,31]],"date-time":"2012-12-31T22:31:12Z","timestamp":1356993072000},"page":"3-9","source":"Crossref","is-referenced-by-count":19,"title":["CSF\/plasma ratios of amino acids: Reference data and transports in children"],"prefix":"10.1016","volume":"36","author":[{"given":"Tomoyuki","family":"Akiyama","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuhiro","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihito","family":"Higashikage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junko","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harumi","family":"Yoshinaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.braindev.2012.12.001_b0005","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1006\/mgme.2001.3224","article-title":"Nonketotic hyperglycinemia (glycine encephalopathy): laboratory diagnosis","volume":"74","author":"Applegarth","year":"2001","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.braindev.2012.12.001_b0010","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0009-9120(79)80084-3","article-title":"Observed range of assay values for plasma and cerebrospinal fluid amino acid levels in infants and children aged 3months to 10years","volume":"12","author":"Applegarth","year":"1979","journal-title":"Clin Biochem"},{"key":"10.1016\/j.braindev.2012.12.001_b0015","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0009-8981(89)90104-6","article-title":"Reference values for amino acids in cerebrospinal fluid of children determined using ion-exchange chromatography with fluorimetric detection","volume":"182","author":"Gerrits","year":"1989","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.braindev.2012.12.001_b0020","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1258\/000456306775141759","article-title":"Reference data for cerebrospinal fluid and the utility of amino acid measurement for the diagnosis of inborn errors of metabolism","volume":"43","author":"Jones","year":"2006","journal-title":"Ann Clin Biochem"},{"key":"10.1016\/j.braindev.2012.12.001_b0025","doi-asserted-by":"crossref","first-page":"e920","DOI":"10.1542\/peds.2007-1631","article-title":"Amino acid cerebrospinal fluid\/plasma ratios in children: influence of age, gender, and antiepileptic medication","volume":"121","author":"Scholl-Burgi","year":"2008","journal-title":"Pediatrics"},{"key":"10.1016\/j.braindev.2012.12.001_b0030","first-page":"394","article-title":"Amino acids in cerebrospinal fluid and plasma: its usefulness in the study of neuropaediatric diseases","volume":"54","author":"Jimenez","year":"2012","journal-title":"Rev Neurol"},{"key":"10.1016\/j.braindev.2012.12.001_b0035","doi-asserted-by":"crossref","first-page":"218S","DOI":"10.1093\/jn\/136.1.218S","article-title":"Structure of the blood\u2013brain barrier and its role in the transport of amino acids","volume":"136","author":"Hawkins","year":"2006","journal-title":"J Nutr"},{"key":"10.1016\/j.braindev.2012.12.001_b0040","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/2045-8118-8-3","article-title":"Molecular biology of the blood\u2013brain and the blood\u2013cerebrospinal fluid barriers: similarities and differences","volume":"8","author":"Redzic","year":"2011","journal-title":"Fluids Barriers CNS"},{"key":"10.1016\/j.braindev.2012.12.001_b0045","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0022-510X(85)90082-6","article-title":"Amino acid transport across the human blood\u2013CSF barrier. An evaluation graph for amino acid concentrations in cerebrospinal fluid","volume":"70","author":"Kruse","year":"1985","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.braindev.2012.12.001_b0050","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.braindev.2011.01.010","article-title":"Vitamin B6 treatment of intractable seizures","volume":"33","author":"Ohtahara","year":"2011","journal-title":"Brain Dev"}],"container-title":["Brain and Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0387760412003051?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0387760412003051?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,3,13]],"date-time":"2020-03-13T17:41:51Z","timestamp":1584121311000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0387760412003051"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["S0387760412003051"],"URL":"https:\/\/doi.org\/10.1016\/j.braindev.2012.12.001","relation":{},"ISSN":["0387-7604"],"issn-type":[{"value":"0387-7604","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]}}}