{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T07:12:32Z","timestamp":1791875552192,"version":"4.3.4"},"reference-count":32,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","brainanddevelopment.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain and Development"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.braindev.2016.04.011","type":"journal-article","created":{"date-parts":[[2016,9,9]],"date-time":"2016-09-09T17:31:57Z","timestamp":1473442317000},"page":"915-927","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":67,"title":["Reversible splenial lesion syndrome in children: Retrospective study and summary of case series"],"prefix":"10.1016","volume":"38","author":[{"given":"Wen-Xiong","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Sheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si-Da","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si-Hui","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan-Yuan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Hong","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Jing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai-Sheng","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-Ci","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-Ning","family":"Mai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.braindev.2016.04.011_b0005","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1212\/01.WNL.0000144274.12174.CB","article-title":"Clinically mild encephalitis\/encephalopathy with a reversible splenial lesion","volume":"63","author":"Tada","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.braindev.2016.04.011_b0010","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.braindev.2009.02.012","article-title":"Two newly proposed infectious encephalitis\/encephalopathy syndromes","volume":"31","author":"Takanashi","year":"2009","journal-title":"Brain Dev"},{"key":"10.1016\/j.braindev.2016.04.011_b0015","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1111\/j.1552-6569.2008.00279.x","article-title":"Reversible splenial lesion syndrome (RESLES): what\u2019s in a name?","volume":"21","author":"Garcia-Monco","year":"2011","journal-title":"J Neuroimaging"},{"key":"10.1016\/j.braindev.2016.04.011_b0020","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.jns.2010.02.013","article-title":"Differences in the time course of splenial and white matter lesions in clinically mild encephalitis\/encephalopathy with a reversible splenial lesion (MERS)","volume":"292","author":"Takanashi","year":"2010","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.braindev.2016.04.011_b0025","first-page":"714","article-title":"Rating scales and assessment instruments for use in pediatric psychopharmacology research","volume":"21","year":"1985","journal-title":"Psychopharmacol Bull"},{"key":"10.1016\/j.braindev.2016.04.011_b0030","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.braindev.2013.05.007","article-title":"Clinico-radiological spectrum of reversible splenial lesions in children","volume":"36","author":"Kashiwagi","year":"2014","journal-title":"Brain Dev"},{"key":"10.1016\/j.braindev.2016.04.011_b0035","first-page":"852","article-title":"The clinical characteristics of children with splenium of corpus callosum solitary lesions displayed on MRI (in Chinese)","volume":"47","author":"Li","year":"2014","journal-title":"Chin J Neurol"},{"key":"10.1016\/j.braindev.2016.04.011_b0040","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.ejpn.2015.01.011","article-title":"Mild encephalopathy with reversible splenial lesion: an important differential of encephalitis","volume":"19","author":"Ka","year":"2015","journal-title":"Eur J Paediatr Neurol"},{"key":"10.1016\/j.braindev.2016.04.011_b0045","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.braindev.2011.07.012","article-title":"Epidemiology of acute encephalopathy in Japan, with emphasis on the association of viruses and syndromes","volume":"34","author":"Hoshino","year":"2012","journal-title":"Brain Dev"},{"key":"10.1016\/j.braindev.2016.04.011_b0050","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s00234-006-0080-5","article-title":"Transient splenium lesions in presurgical epilepsy patients: incidence and pathogenesis","volume":"48","author":"Nelles","year":"2006","journal-title":"Neuroradiology"},{"key":"10.1016\/j.braindev.2016.04.011_b0055","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.pediatrneurol.2012.11.007","article-title":"Mild encephalopathy with splenial lesion and parainfluenza virus infection","volume":"48","author":"Abenhaim Halpern","year":"2013","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.braindev.2016.04.011_b0060","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.pediatrneurol.2015.06.016","article-title":"Pediatric hemorrhagic brainstem encephalitis associated with HHV-7 infection","volume":"53","author":"Fay","year":"2015","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.braindev.2016.04.011_b0065","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.pediatrneurol.2014.05.021","article-title":"Clinically mild encephalitis\/encephalopathy with a reversible splenial lesion caused by human parvovirus b19 infection: a case of two brothers with hereditary spherocytosis","volume":"51","author":"Suzuki","year":"2014","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.braindev.2016.04.011_b0070","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.cyto.2011.01.006","article-title":"Serum and cerebrospinal fluid cytokine profile of patients with 2009 pandemic H1N1 influenza virus-associated encephalopathy","volume":"54","author":"Hasegawa","year":"2011","journal-title":"Cytokine"},{"key":"10.1016\/j.braindev.2016.04.011_b0075","first-page":"67","article-title":"Mild encephalitis\/encephalopathy with a reversible splenial lesion in children","volume":"66","author":"Liptai","year":"2013","journal-title":"Ideggyogy Sz"},{"key":"10.1016\/j.braindev.2016.04.011_b0080","first-page":"836","article-title":"Widening spectrum of a reversible splenial lesion with transiently reduced diffusion","volume":"27","author":"Takanashi","year":"2006","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.braindev.2016.04.011_b0085","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1111\/j.1442-200X.2010.03221.x","article-title":"Rotavirus encephalitis and cerebellitis with reversible magnetic resonance signal changes","volume":"53","author":"Mori","year":"2011","journal-title":"Pediatr Int"},{"key":"10.1016\/j.braindev.2016.04.011_b0090","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s10156-012-0421-8","article-title":"A 4-year-old girl with clinically mild encephalopathy with a reversible splenial lesion associated with rotavirus infection","volume":"19","author":"Fuchigami","year":"2013","journal-title":"J Infect Chemother"},{"key":"10.1016\/j.braindev.2016.04.011_b0095","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1007\/s00381-015-2646-1","article-title":"Transient lesion in the splenium of the corpus callosum due to rotavirus infection","volume":"31","author":"Mazur-Melewska","year":"2015","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.braindev.2016.04.011_b0100","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1177\/0883073807307083","article-title":"Rotavirus-induced seizures in childhood","volume":"22","author":"DiFazio","year":"2007","journal-title":"J Child Neurol"},{"key":"10.1016\/j.braindev.2016.04.011_b0105","first-page":"449","article-title":"Recurrence of transient splenial lesions in a child with \u201cbenign convulsions with gastroenteritis\u201d (in Japanese)","volume":"42","author":"Morioka","year":"2010","journal-title":"No To Hattatsu"},{"key":"10.1016\/j.braindev.2016.04.011_b0110","doi-asserted-by":"crossref","first-page":"213","DOI":"10.3348\/jksr.2011.64.3.213","article-title":"Recurrent clinically mild encephalitis\/encephalopathy with a reversible splenial lesion (MERS) on diffusion weighted imaging: a case report","volume":"64","author":"Hong","year":"2011","journal-title":"J Korean Soc Radiol"},{"key":"10.1016\/j.braindev.2016.04.011_b0115","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.jns.2009.12.004","article-title":"Sisters with clinically mild encephalopathy with a reversible splenial lesion (MERS)-like features; familial MERS?","volume":"290","author":"Imamura","year":"2010","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.braindev.2016.04.011_b0120","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.pediatrneurol.2012.10.003","article-title":"Expanding the spectrum of MERS type 2 lesions, a particular form of encephalitis","volume":"48","author":"Notebaert","year":"2013","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.braindev.2016.04.011_b0125","series-title":"Proceedings of the 34th annual meeting of the American Society of Neuroradiology","article-title":"Transient splenial edema in epilepsy: MR imaging evaluation","author":"Chason","year":"1996"},{"key":"10.1016\/j.braindev.2016.04.011_b0130","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1017\/S0317167100004261","article-title":"Transient edematous lesions of the splenium in epileptic patients","volume":"32","author":"Carrara","year":"2005","journal-title":"Can J Neurol Sci"},{"key":"10.1016\/j.braindev.2016.04.011_b0135","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1111\/j.1528-1167.2005.00256.x","article-title":"Reversible cytotoxic edema in the splenium of the corpus callosum related to antiepileptic treatment: report of two cases and literature review","volume":"46","author":"Prilipko","year":"2005","journal-title":"Epilepsia"},{"key":"10.1016\/j.braindev.2016.04.011_b0140","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.3174\/ajnr.A2131","article-title":"Clinical and radiological features of rotavirus cerebellitis","volume":"31","author":"Takanashi","year":"2010","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.braindev.2016.04.011_b0145","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.braindev.2008.04.002","article-title":"Encephalopathy with a reversible splenial lesion is associated with hyponatremia","volume":"31","author":"Takanashi","year":"2009","journal-title":"Brain Dev"},{"key":"10.1016\/j.braindev.2016.04.011_b0150","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1001\/archneur.62.3.433","article-title":"Clinical implications of splenium magnetic resonance imaging signal changes","volume":"62","author":"Doherty","year":"2005","journal-title":"Arch Neurol"},{"key":"10.1016\/j.braindev.2016.04.011_b0155","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.braindev.2011.04.004","article-title":"Oxidative stress in patients with clinically mild encephalitis\/encephalopathy with a reversible splenial lesion (MERS)","volume":"34","author":"Miyata","year":"2012","journal-title":"Brain Dev"},{"key":"10.1016\/j.braindev.2016.04.011_b0160","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1007\/s00234-007-0235-z","article-title":"Reversible focal splenial lesions","volume":"49","author":"Gallucci","year":"2007","journal-title":"Neuroradiology"}],"container-title":["Brain and Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0387760416300535?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0387760416300535?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,8]],"date-time":"2018-09-08T16:51:30Z","timestamp":1536425490000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0387760416300535"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":32,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["S0387760416300535"],"URL":"https:\/\/doi.org\/10.1016\/j.braindev.2016.04.011","relation":{},"ISSN":["0387-7604"],"issn-type":[{"value":"0387-7604","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Reversible splenial lesion syndrome in children: Retrospective study and summary of case series","name":"articletitle","label":"Article Title"},{"value":"Brain and Development","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.braindev.2016.04.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}