{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T13:45:32Z","timestamp":1790862332777,"version":"4.1.0"},"reference-count":67,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["RR019478"],"award-info":[{"award-number":["RR019478"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["HD061222"],"award-info":[{"award-number":["HD061222"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["HD38985"],"award-info":[{"award-number":["HD38985"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001819","name":"International Rett Syndrome Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001819","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006464","name":"Civitan International Research Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006464","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["brainanddevelopment.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain and Development"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1016\/j.braindev.2018.03.010","type":"journal-article","created":{"date-parts":[[2018,4,12]],"date-time":"2018-04-12T20:07:30Z","timestamp":1523563650000},"page":"515-529","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":94,"title":["The course of awake breathing disturbances across the lifespan in Rett syndrome"],"prefix":"10.1016","volume":"40","author":[{"given":"Daniel C.","family":"Tarquinio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey L.","family":"Neul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gamze Kilic","family":"Berkmen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Drummond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Aronoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane B.","family":"Lane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter E.","family":"Kaufmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen J.","family":"Motil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel G.","family":"Glaze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven A.","family":"Skinner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan K.","family":"Percy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.braindev.2018.03.010_b0005","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1016\/j.ridd.2013.01.014","article-title":"Changing the perspective on early development of Rett syndrome","volume":"34","author":"Marschik","year":"2013","journal-title":"Res Dev Disabil"},{"key":"10.1016\/j.braindev.2018.03.010_b0010","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/1866-1955-6-20","article-title":"Developmental delay in Rett syndrome: data from the natural history study","volume":"6","author":"Neul","year":"2014","journal-title":"J Neurodev Disord"},{"key":"10.1016\/j.braindev.2018.03.010_b0015","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/S0387-7604(85)80040-1","article-title":"Rett syndrome \u2013 an early catecholamine and indolamine deficient disorder?","volume":"7","author":"Nomura","year":"1985","journal-title":"Brain Dev"},{"key":"10.1016\/j.braindev.2018.03.010_b0020","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1177\/08830738050200091201","article-title":"Natural history of Rett syndrome","volume":"20","author":"Nomura","year":"2005","journal-title":"J Child Neurol"},{"key":"10.1016\/j.braindev.2018.03.010_b0025","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/nrneurol.2016.186","article-title":"Clinical and biological progress over 50 years in Rett syndrome","volume":"13","author":"Leonard","year":"2017","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.braindev.2018.03.010_b0030","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1093\/brain\/aww302","article-title":"Longitudinal course of epilepsy in Rett syndrome and related disorders","volume":"140","author":"Tarquinio","year":"2017","journal-title":"Brain"},{"key":"10.1016\/j.braindev.2018.03.010_b0035","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1136\/adc.85.1.29","article-title":"Characterisation of breathing and associated central autonomic dysfunction in the Rett disorder","volume":"85","author":"Julu","year":"2001","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.braindev.2018.03.010_b0040","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1097\/MPG.0b013e31824b6159","article-title":"Gastrointestinal and nutritional problems occur frequently throughout life in girls and women with Rett syndrome","volume":"55","author":"Motil","year":"2012","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.braindev.2018.03.010_b0045","series-title":"Cerebral atrophy associated with hyperammonaemia","author":"Rett","year":"1977"},{"key":"10.1016\/j.braindev.2018.03.010_b0050","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1002\/ana.410140412","article-title":"A progressive syndrome of autism, dementia, ataxia, and loss of purposeful hand use in girls: Rett's syndrome: report of 35 cases","volume":"14","author":"Hagberg","year":"1983","journal-title":"Ann Neurol"},{"key":"10.1016\/j.braindev.2018.03.010_b0055","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/S0387-7604(85)80039-5","article-title":"Abnormal breathing in the Rett syndrome","volume":"7","author":"Lugaresi","year":"1985","journal-title":"Brain Dev"},{"key":"10.1016\/j.braindev.2018.03.010_b0060","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.pediatrneurol.2015.06.003","article-title":"The changing face of survival in Rett syndrome and MECP2-related disorders","volume":"53","author":"Tarquinio","year":"2015","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.braindev.2018.03.010_b0065","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1203\/01.pdr.0000203157.31924.4a","article-title":"Separate respiratory phenotypes in methyl-CpG-binding protein 2 (Mecp2) deficient mice","volume":"59","author":"Bissonnette","year":"2006","journal-title":"Pediatr Res"},{"issue":"Suppl 1","key":"10.1016\/j.braindev.2018.03.010_b0070","first-page":"71","article-title":"Rett syndrome: analysis of deaths in the British survey","volume":"6","author":"Kerr","year":"1997","journal-title":"Eur Child Adolesc Psychiatry"},{"key":"10.1016\/j.braindev.2018.03.010_b0075","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1203\/01.pdr.0000238302.84552.d0","article-title":"Autonomic nervous system dysregulation: breathing and heart rate perturbation during wakefulness in young girls with Rett syndrome","volume":"60","author":"Weese-Mayer","year":"2006","journal-title":"Pediatr Res"},{"key":"10.1016\/j.braindev.2018.03.010_b0080","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1136\/adc.80.4.384","article-title":"Recent insights into hyperventilation from the study of Rett syndrome","volume":"80","author":"Kerr","year":"1999","journal-title":"Arch Dis Child"},{"issue":"Suppl","key":"10.1016\/j.braindev.2018.03.010_b0085","first-page":"S43","article-title":"A review of the respiratory disorder in the Rett syndrome","volume":"14","author":"Kerr","year":"1992","journal-title":"Brain Dev"},{"key":"10.1016\/j.braindev.2018.03.010_b0090","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.resp.2013.06.022","article-title":"Breathing challenges in Rett syndrome: lessons learned from humans and animal models","volume":"189","author":"Ramirez","year":"2013","journal-title":"Respir Physiol Neurobiol"},{"key":"10.1016\/j.braindev.2018.03.010_b0095","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s12263-012-0285-7","article-title":"Partial rescue of Rett syndrome by omega-3 polyunsaturated fatty acids (PUFAs) oil","volume":"7","author":"De Felice","year":"2012","journal-title":"Genes Nutr"},{"issue":"Suppl 1","key":"10.1016\/j.braindev.2018.03.010_b0100","first-page":"47","article-title":"Functional evidence of brain stem immaturity in Rett syndrome","volume":"6","author":"Julu","year":"1997","journal-title":"Eur Child Adolesc Psychiatry"},{"key":"10.1016\/j.braindev.2018.03.010_b0105","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1002\/ana.410210410","article-title":"Rett's syndrome: characterization of respiratory patterns and sleep","volume":"21","author":"Glaze","year":"1987","journal-title":"Ann Neurol"},{"key":"10.1016\/j.braindev.2018.03.010_b0110","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1002\/ppul.20866","article-title":"Autonomic dysregulation in young girls with Rett syndrome during nighttime in-home recordings","volume":"43","author":"Weese-Mayer","year":"2008","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.braindev.2018.03.010_b0115","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/s10072-009-0108-9","article-title":"Central sleep apnoea in Rett syndrome","volume":"30","author":"d'Orsi","year":"2009","journal-title":"Neurol Sci"},{"key":"10.1016\/j.braindev.2018.03.010_b0120","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/S0022-3476(94)70196-2","article-title":"Polysomnographic characteristics of patients with Rett syndrome","volume":"125","author":"Marcus","year":"1994","journal-title":"J Pediatr"},{"key":"10.1016\/j.braindev.2018.03.010_b0125","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.pediatrneurol.2007.06.009","article-title":"Disturbances in cardiorespiratory function during day and night in Rett syndrome","volume":"37","author":"Rohdin","year":"2007","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.braindev.2018.03.010_b0130","series-title":"Rett Clinics Conference Call","article-title":"Breathless: quantifying and qualifying breathing dysfunction in Rett syndrome","author":"Tarquinio","year":"2014"},{"key":"10.1016\/j.braindev.2018.03.010_b0135","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.braindev.2012.04.004","article-title":"Treating hypoxia in a feeble breather with Rett syndrome","volume":"35","author":"Julu","year":"2013","journal-title":"Brain Dev"},{"key":"10.1016\/j.braindev.2018.03.010_b0140","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.braindev.2006.04.010","article-title":"Management of a severe forceful breather with Rett syndrome using carbogen","volume":"28","author":"Smeets","year":"2006","journal-title":"Brain Dev"},{"key":"10.1016\/j.braindev.2018.03.010_b0145","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.braindev.2004.09.011","article-title":"Buspirone in Rett syndrome respiratory dysfunction","volume":"27","author":"Andaku","year":"2005","journal-title":"Brain Dev"},{"key":"10.1016\/j.braindev.2018.03.010_b0150","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.pediatrneurol.2011.12.003","article-title":"Use of buspirone and fluoxetine for breathing problems in Rett syndrome","volume":"46","author":"Gokben","year":"2012","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.braindev.2018.03.010_b0155","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1002\/ana.410350415","article-title":"Rett syndrome: controlled study of an oral opiate antagonist, naltrexone","volume":"35","author":"Percy","year":"1994","journal-title":"Ann Neurol"},{"key":"10.1016\/j.braindev.2018.03.010_b0160","doi-asserted-by":"crossref","first-page":"4596","DOI":"10.1073\/pnas.1311141111","article-title":"Safety, pharmacokinetics, and preliminary assessment of efficacy of mecasermin (recombinant human IGF-1) for the treatment of Rett syndrome","volume":"111","author":"Khwaja","year":"2014","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.braindev.2018.03.010_b0165","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1212\/WNL.0b013e3181d6b852","article-title":"Epilepsy and the natural history of Rett syndrome","volume":"74","author":"Glaze","year":"2010","journal-title":"Neurology"},{"key":"10.1016\/j.braindev.2018.03.010_b0170","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1212\/WNL.0b013e31826e9a70","article-title":"Growth failure and outcome in Rett syndrome: specific growth references","volume":"79","author":"Tarquinio","year":"2012","journal-title":"Neurology"},{"key":"10.1016\/j.braindev.2018.03.010_b0175","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1053\/ejpn.2002.0612","article-title":"An update on clinically applicable diagnostic criteria in Rett syndrome. comments to Rett syndrome clinical criteria consensus panel satellite to european paediatric neurology society meeting, baden baden, Germany, 11 September 2001","volume":"6","author":"Hagberg","year":"2002","journal-title":"Eur J Paediatr Neurol"},{"key":"10.1016\/j.braindev.2018.03.010_b0180","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1002\/ana.22154","article-title":"Rett syndrome diagnostic criteria: lessons from the natural history study","volume":"68","author":"Percy","year":"2010","journal-title":"Ann Neurol"},{"issue":"585\u201391","key":"10.1016\/j.braindev.2018.03.010_b0185","first-page":"e2","article-title":"Age of diagnosis in Rett syndrome: patterns of recognition among diagnosticians and risk factors for late diagnosis","volume":"52","author":"Tarquinio","year":"2015","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.braindev.2018.03.010_b0190","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/mds.870050303","article-title":"Rett syndrome and associated movement disorders","volume":"5","author":"FitzGerald","year":"1990","journal-title":"Mov Disord"},{"key":"10.1016\/j.braindev.2018.03.010_b0195","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1212\/01.wnl.0000291011.54508.aa","article-title":"Specific mutations in methyl-CpG-binding protein 2 confer different severity in Rett syndrome","volume":"70","author":"Neul","year":"2008","journal-title":"Neurology"},{"key":"10.1016\/j.braindev.2018.03.010_b0200","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0002-8223(00)00021-3","article-title":"Descriptive anthropometric reference data for older Americans","volume":"100","author":"Kuczmarski","year":"2000","journal-title":"J Am Diet Assoc"},{"key":"10.1016\/j.braindev.2018.03.010_b0205","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1002\/(SICI)1097-0258(19980228)17:4<407::AID-SIM742>3.0.CO;2-L","article-title":"British 1990 growth reference centiles for weight, height, body mass index and head circumference fitted by maximum penalized likelihood","volume":"17","author":"Cole","year":"1998","journal-title":"Stat Med"},{"key":"10.1016\/j.braindev.2018.03.010_b0210","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1097\/MPG.0b013e31829e0b65","article-title":"Assessment and management of nutrition and growth in Rett syndrome","volume":"57","author":"Leonard","year":"2013","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.braindev.2018.03.010_b0215","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1136\/jmedgenet-2013-102113","article-title":"Methyl-CpG-binding protein 2 (MECP2) mutation type is associated with disease severity in Rett syndrome","volume":"51","author":"Cuddapah","year":"2014","journal-title":"J Med Genet"},{"key":"10.1016\/j.braindev.2018.03.010_b0220","series-title":"SAS Institute Inc. version 9.4 ed.","author":"SAS Institute Inc.","year":"2016"},{"key":"10.1016\/j.braindev.2018.03.010_b0225","series-title":"IBM SPSS Statistics for Windows. version 22.0 ed.","author":"IBM Corp.","year":"2013"},{"key":"10.1016\/j.braindev.2018.03.010_b0230","series-title":"ArcMap Editor. version 10.1 ed.","author":"Esri Inc.","year":"2012"},{"key":"10.1016\/j.braindev.2018.03.010_b0235","series-title":"Address Coder. version 10.1 ed.","author":"Esri Inc.","year":"2014"},{"key":"10.1016\/j.braindev.2018.03.010_b0240","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/j.pediatrneurol.2014.08.013","article-title":"Pubertal development in rett syndrome deviates from typical females","volume":"51","author":"Killian","year":"2014","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.braindev.2018.03.010_b0245","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.tins.2015.12.008","article-title":"Rett syndrome: crossing the threshold to clinical translation","volume":"39","author":"Katz","year":"2016","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.braindev.2018.03.010_b0250","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1177\/088307380101600512","article-title":"Progressive cardiac dysautonomia observed in patients affected by classic Rett syndrome and not in the preserved speech variant","volume":"16","author":"Guideri","year":"2001","journal-title":"J Child Neurol"},{"key":"10.1016\/j.braindev.2018.03.010_b0255","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1136\/adc.77.5.463c","article-title":"Immaturity of medullary cardiorespiratory neurones leading to inappropriate autonomic reactions as a likely cause of sudden death in Rett's syndrome","volume":"77","author":"Julu","year":"1997","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.braindev.2018.03.010_b0260","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1038\/85906","article-title":"Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice","volume":"27","author":"Chen","year":"2001","journal-title":"Nat Genet"},{"key":"10.1016\/j.braindev.2018.03.010_b0265","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1038\/85899","article-title":"A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome","volume":"27","author":"Guy","year":"2001","journal-title":"Nat Genet"},{"key":"10.1016\/j.braindev.2018.03.010_b0270","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1126\/science.1138389","article-title":"Reversal of neurological defects in a mouse model of Rett syndrome","volume":"315","author":"Guy","year":"2007","journal-title":"Science"},{"key":"10.1016\/j.braindev.2018.03.010_b0275","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.resp.2009.04.017","article-title":"Breathing disorders in Rett syndrome: progressive neurochemical dysfunction in the respiratory network after birth","volume":"168","author":"Katz","year":"2009","journal-title":"Respir Physiol Neurobiol"},{"key":"10.1016\/j.braindev.2018.03.010_b0280","doi-asserted-by":"crossref","first-page":"10911","DOI":"10.1523\/JNEUROSCI.1810-06.2006","article-title":"Dysregulation of brain-derived neurotrophic factor expression and neurosecretory function in Mecp2 null mice","volume":"26","author":"Wang","year":"2006","journal-title":"J Neurosci"},{"key":"10.1016\/j.braindev.2018.03.010_b0285","doi-asserted-by":"crossref","first-page":"10912","DOI":"10.1523\/JNEUROSCI.1869-07.2007","article-title":"Brain-derived neurotrophic factor expression and respiratory function improve after ampakine treatment in a mouse model of Rett syndrome","volume":"27","author":"Ogier","year":"2007","journal-title":"J Neurosci"},{"key":"10.1016\/j.braindev.2018.03.010_b0290","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1523\/JNEUROSCI.0865-11.2012","article-title":"A TrkB small molecule partial agonist rescues TrkB phosphorylation deficits and improves respiratory function in a mouse model of Rett syndrome","volume":"32","author":"Schmid","year":"2012","journal-title":"J Neurosci"},{"key":"10.1016\/j.braindev.2018.03.010_b0295","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.resp.2007.08.009","article-title":"Oral treatment with desipramine improves breathing and life span in Rett syndrome mouse model","volume":"160","author":"Zanella","year":"2008","journal-title":"Respir Physiol Neurobiol"},{"key":"10.1016\/j.braindev.2018.03.010_b0300","doi-asserted-by":"crossref","first-page":"18208","DOI":"10.1073\/pnas.1012104107","article-title":"Correction of respiratory disorders in a mouse model of Rett syndrome","volume":"107","author":"Abdala","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.braindev.2018.03.010_b0305","doi-asserted-by":"crossref","first-page":"13860","DOI":"10.1523\/JNEUROSCI.2159-12.2012","article-title":"Brain activity mapping in Mecp2 mutant mice reveals functional deficits in forebrain circuits, including key nodes in the default mode network, that are reversed with ketamine treatment","volume":"32","author":"Kron","year":"2012","journal-title":"J Neurosci"},{"issue":"Suppl 1","key":"10.1016\/j.braindev.2018.03.010_b0310","doi-asserted-by":"crossref","first-page":"S240","DOI":"10.1016\/S0387-7604(01)00341-2","article-title":"A case of effective gastrostomy for severe abdominal distention due to breathing dysfunction of Rett's syndrome: a treatment of autonomic disorder","volume":"23","author":"Anzai","year":"2001","journal-title":"Brain Dev"},{"key":"10.1016\/j.braindev.2018.03.010_b0315","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1002\/ajmg.1320250525","article-title":"Therapeutic effects of a ketogenic diet in Rett syndrome","volume":"25","author":"Haas","year":"1986","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.braindev.2018.03.010_b0320","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1177\/088307380401900804","article-title":"Effect of topiramate on seizures and respiratory dysrhythmia in Rett syndrome","volume":"19","author":"Goyal","year":"2004","journal-title":"J Child Neurol"},{"key":"10.1016\/j.braindev.2018.03.010_b0325","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1002\/(SICI)1096-8628(19980123)75:3<273::AID-AJMG9>3.0.CO;2-R","article-title":"Mental retardation, \u201ccoarse\u201d face, and hyperbreathing: confirmation of the Pitt-Hopkins syndrome","volume":"75","author":"Van Balkom","year":"1998","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.braindev.2018.03.010_b0330","unstructured":"Parisi M, Glass I. Joubert Syndrome. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Mefford HC, et al., editors. GeneReviews(R). Seattle (WA); 1993."},{"key":"10.1016\/j.braindev.2018.03.010_b0335","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1177\/0883073811429859","article-title":"Respiratory disturbances in rett syndrome: don't forget to evaluate upper airway obstruction","volume":"27","author":"Hagebeuk","year":"2012","journal-title":"J Child Neurol"}],"container-title":["Brain and Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0387760418301062?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0387760418301062?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T19:48:31Z","timestamp":1759952911000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0387760418301062"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":67,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["S0387760418301062"],"URL":"https:\/\/doi.org\/10.1016\/j.braindev.2018.03.010","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.733059037.793586474","asserted-by":"object"}]},"ISSN":["0387-7604"],"issn-type":[{"value":"0387-7604","type":"print"}],"subject":[],"published":{"date-parts":[[2018,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The course of awake breathing disturbances across the lifespan in Rett syndrome","name":"articletitle","label":"Article Title"},{"value":"Brain and Development","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.braindev.2018.03.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}