{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T03:31:18Z","timestamp":1784086278279,"version":"3.55.0"},"reference-count":7,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T00:00:00Z","timestamp":1590969600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["brainanddevelopment.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain and Development"],"published-print":{"date-parts":[[2020,6]]},"DOI":"10.1016\/j.braindev.2020.03.003","type":"journal-article","created":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T17:29:26Z","timestamp":1585762166000},"page":"473-476","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Improvement of epilepsy with lacosamide in a patient with ring chromosome 20 syndrome"],"prefix":"10.1016","volume":"42","author":[{"given":"Takahiro","family":"Tayama","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuo","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aya","family":"Goji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiro","family":"Toda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoji","family":"Kagami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.braindev.2020.03.003_b0005","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1136\/jmg.9.3.377","article-title":"A ring-20 chromosome","volume":"9","author":"Atkins","year":"1972","journal-title":"J Med Genet"},{"key":"10.1016\/j.braindev.2020.03.003_b0010","series-title":"Epileptic syndromes in infancy, childhood and adolescence","first-page":"545","article-title":"Epilepsies and chromosomal disorders","author":"Genton","year":"2012"},{"key":"10.1016\/j.braindev.2020.03.003_b0015","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.eplepsyres.2016.10.004","article-title":"Epilepsy in ring chromosome 20 syndrome","volume":"128","author":"Vignoli","year":"2016","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.braindev.2020.03.003_b0020","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1093\/brain\/120.6.939","article-title":"Ring chromosome 20 and nonconvulsive status epilepticus. A new epileptic syndrome","volume":"120","author":"Inoue","year":"1997","journal-title":"Brain"},{"key":"10.1016\/j.braindev.2020.03.003_b0025","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1177\/1550059415593428","article-title":"Significant improvements of EEG and clinical findings with oral lacosamide in a patient with ring chromosome 20","volume":"47","author":"Onder","year":"2016","journal-title":"Clin EEG Neurosci"},{"key":"10.1016\/j.braindev.2020.03.003_b0030","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.seizure.2012.10.004","article-title":"Efficacy of intravenous lacosamide as an add-on treatment in refractory status epilepticus: a multicentric prospective study","volume":"22","author":"Miro","year":"2013","journal-title":"Seizure"},{"key":"10.1016\/j.braindev.2020.03.003_b0035","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.eplepsyres.2016.12.015","article-title":"Lacosamide for uncontrolled primary generalized tonic-clonic seizures: an open-label pilot study with 59-week extension","volume":"130","author":"Wechsler","year":"2017","journal-title":"Epilepsy Res"}],"container-title":["Brain and Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0387760420301091?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0387760420301091?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T19:48:35Z","timestamp":1759952915000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0387760420301091"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6]]},"references-count":7,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["S0387760420301091"],"URL":"https:\/\/doi.org\/10.1016\/j.braindev.2020.03.003","relation":{},"ISSN":["0387-7604"],"issn-type":[{"value":"0387-7604","type":"print"}],"subject":[],"published":{"date-parts":[[2020,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Improvement of epilepsy with lacosamide in a patient with ring chromosome 20 syndrome","name":"articletitle","label":"Article Title"},{"value":"Brain and Development","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.braindev.2020.03.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}