{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T05:25:07Z","timestamp":1766467507657,"version":"build-2065373602"},"reference-count":19,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["brainanddevelopment.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain and Development"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.braindev.2020.12.003","type":"journal-article","created":{"date-parts":[[2021,1,8]],"date-time":"2021-01-08T18:44:35Z","timestamp":1610131475000},"page":"538-547","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Malaysian outcome of acute necrotising encephalopathy of childhood"],"prefix":"10.1016","volume":"43","author":[{"given":"Choong Yi","family":"Fong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mon Thandar","family":"Saw","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Limin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei Kang","family":"Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lai Choo","family":"Ong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chin Seng","family":"Gan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.braindev.2020.12.003_b0005","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0387-7604(96)00063-0","article-title":"Acute necrotizing encephalopathy in childhood: a novel form of acute encephalopathy prevalent in Japan and Taiwan","volume":"19","author":"Mizuguchi","year":"1997","journal-title":"Brain Dev"},{"key":"10.1016\/j.braindev.2020.12.003_b0010","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1136\/jnnp.58.5.555","article-title":"Acute necrotizing encephalopathy of childhood: a new syndrome presenting with multifocal, symmetric brain lesions","volume":"58","author":"Mizuguchi","year":"1995","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"6","key":"10.1016\/j.braindev.2020.12.003_b0015","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.pediatrneurol.2011.09.007","article-title":"Cytokine storm of acute necrotizing encephalopathy","volume":"45","author":"Kansagra","year":"2011","journal-title":"Pediatr Neurol"},{"doi-asserted-by":"crossref","unstructured":"Okumura A, Abe S, Kidokoro H, Mizuguchi M. Acute necrotizing encephalopathy: a comparison between influenza and non- influenza cases. Microbiol Immunol 2009; 53: 277\u201380.","key":"10.1016\/j.braindev.2020.12.003_b0020","DOI":"10.1111\/j.1348-0421.2009.00124.x"},{"doi-asserted-by":"crossref","unstructured":"Okumura A, Mizuguchi M, Kidokoro H. Outcome of acute necrotizing encephalopathy in relation to treatment with corticosteroids and gammaglobulin. Brain Dev 2009; 31: 221\u20137.","key":"10.1016\/j.braindev.2020.12.003_b0025","DOI":"10.1016\/j.braindev.2008.03.005"},{"issue":"10","key":"10.1016\/j.braindev.2020.12.003_b0030","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1177\/0883073820927915","article-title":"Presentation and outcome of acute necrotizing encephalopathy of childhood: a 10-year single-center retrospective study from Hong Kong","volume":"35","author":"Chow","year":"2020","journal-title":"J Child Neurol"},{"issue":"07","key":"10.1016\/j.braindev.2020.12.003_b0035","doi-asserted-by":"crossref","first-page":"649","DOI":"10.29271\/jcpsp.2019.07.649","article-title":"Acute Necrotizing Encephalopathy","volume":"29","author":"Jan","year":"2019","journal-title":"J Coll Physicians Surg Pak"},{"issue":"3","key":"10.1016\/j.braindev.2020.12.003_b0040","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.braindev.2014.05.007","article-title":"A severity score for acute necrotizing encephalopathy","volume":"37","author":"Yamamoto","year":"2015","journal-title":"Brain and Development"},{"issue":"3","key":"10.1016\/j.braindev.2020.12.003_b0045","doi-asserted-by":"crossref","first-page":"449","DOI":"10.3346\/jkms.2010.25.3.449","article-title":"Clinical spectrum and prognostic factors of acute necrotizing encephalopathy in children","volume":"25","author":"Seo","year":"2010","journal-title":"J Korean Med Sci"},{"issue":"3","key":"10.1016\/j.braindev.2020.12.003_b0050","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3348\/kjr.2004.5.3.171","article-title":"Acute necrotizing encephalopathy in korean infants and children: imaging findings and diverse clinical outcome","volume":"5","author":"Kim","year":"2004","journal-title":"Korean J Radiol"},{"key":"10.1016\/j.braindev.2020.12.003_b0055","doi-asserted-by":"crossref","first-page":"264","DOI":"10.3345\/kjp.2014.57.6.264","article-title":"Clinical outcome of acute necrotising encephalopathy in related to involving the brain stem of single institution in Korea","volume":"57","author":"Lee","year":"2014","journal-title":"Korean J Pediatr"},{"issue":"10","key":"10.1016\/j.braindev.2020.12.003_b0060","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1016\/j.braindev.2019.07.007","article-title":"Neuropsychological outcomes of childhood acute necrotizing encephalopathy","volume":"41","author":"Williams","year":"2019","journal-title":"Brain and Development"},{"key":"10.1016\/j.braindev.2020.12.003_b0065","first-page":"1919","article-title":"Acute necrotizing encephalopathy of childhood: correlation of MR findings and clinical outcome","volume":"27","author":"Wong","year":"2006","journal-title":"AJNR Am J Neuroradiol"},{"issue":"10","key":"10.1016\/j.braindev.2020.12.003_b0070","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1016\/j.braindev.2016.05.002","article-title":"Serial outcomes in acute necrotising encephalopathy of childhood: A medium and long term study","volume":"38","author":"Lim","year":"2016","journal-title":"Brain and Development"},{"issue":"6","key":"10.1016\/j.braindev.2020.12.003_b0075","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1089\/neu.2011.2272","article-title":"Validity of a Pediatric Version of the Glasgow Outcome Scale\u2013Extended","volume":"29","author":"Beers","year":"2012","journal-title":"J Neurotrauma"},{"key":"10.1016\/j.braindev.2020.12.003_b0080","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/S0022-3476(05)82544-2","article-title":"Assessing the outcome of paediatric intensive care","volume":"121","author":"Fiser","year":"1992","journal-title":"J Pediatr"},{"key":"10.1016\/j.braindev.2020.12.003_b0085","doi-asserted-by":"crossref","first-page":"2616","DOI":"10.1097\/00003246-200007000-00072","article-title":"Relationship of pediatric overall performance category and pediatric cerebral performance category scores at pediatric intensive care unit discharge with outcome measures collected at hospital discharge and 1- and 6-month follow-up assessments","volume":"28","author":"Fiser","year":"2000","journal-title":"Crit Care Med"},{"issue":"7","key":"10.1016\/j.braindev.2020.12.003_b0090","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1001\/jamapediatrics.2013.5316","article-title":"Relationship Between the Functional Status Scale and the Pediatric Overall Performance Category and Pediatric Cerebral Performance Category Scales","volume":"168","author":"Pollack","year":"2014","journal-title":"JAMA Pediatr"},{"key":"10.1016\/j.braindev.2020.12.003_b0095","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.pediatrneurol.2019.04.009","article-title":"Favorable outcomes with early interleukin 6 receptor blockade in severe acute necrotizing encephalopathy of childhood","volume":"98","author":"Koh","year":"2019","journal-title":"Pediatr Neurol"}],"container-title":["Brain and Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0387760420303272?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0387760420303272?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T19:49:12Z","timestamp":1759952952000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0387760420303272"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["S0387760420303272"],"URL":"https:\/\/doi.org\/10.1016\/j.braindev.2020.12.003","relation":{},"ISSN":["0387-7604"],"issn-type":[{"type":"print","value":"0387-7604"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Malaysian outcome of acute necrotising encephalopathy of childhood","name":"articletitle","label":"Article Title"},{"value":"Brain and Development","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.braindev.2020.12.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Japanese Society of Child Neurology Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}